| ETV5 facilitates tumor progression in head-neck squamous cell carcinoma. | ETV5 facilitates tumor progression in head-neck squamous cell carcinoma.
Yu S, Ma Z, Chen T, Wang H, Yao Q, Li J, Cheng J. | 07/3/2024 |
| ETV5 promotes lupus pathogenesis and follicular helper T cell differentiation by inducing osteopontin expression. | ETV5 promotes lupus pathogenesis and follicular helper T cell differentiation by inducing osteopontin expression.
Park J, Lee J, Hur Y, Kim CJ, Kim HB, Um D, Kim DS, Lee JY, Park S, Park Y, Kim TK, Im SH, Kim SW, Kwok SK, Lee Y., | 06/17/2024 |
| YTHDF2 Is a Therapeutic Target for HCC by Suppressing Immune Evasion and Angiogenesis Through ETV5/PD-L1/VEGFA Axis. | YTHDF2 Is a Therapeutic Target for HCC by Suppressing Immune Evasion and Angiogenesis Through ETV5/PD-L1/VEGFA Axis.
Wen J, Xue L, Wei Y, Liang J, Jia W, Yong T, Chu L, Li H, Han S, Liao J, Chen Z, Liu Y, Liu Q, Ding Z, Liang H, Gan L, Chen X, Huang Z, Zhang B., Free PMC Article | 04/15/2024 |
| ETV5 transcriptionally activates TGFbeta1 and promotes cancer cell invasion and migration of NSCLC. | ETV5 transcriptionally activates TGFβ1 and promotes cancer cell invasion and migration of NSCLC.
Li D, Shen Y, Ren H, Wang L, Yang J, Wang Y. | 10/2/2023 |
| E26 transformation-specific transcription variant 5 in development and cancer: modification, regulation and function. | E26 transformation-specific transcription variant 5 in development and cancer: modification, regulation and function.
Wei Y, Han S, Wen J, Liao J, Liang J, Yu J, Chen X, Xiang S, Huang Z, Zhang B., Free PMC Article | 08/9/2023 |
| ETV5 overexpression promotes progression of esophageal squamous cell carcinoma by upregulating SKA1 and TRPV2. | ETV5 overexpression promotes progression of esophageal squamous cell carcinoma by upregulating SKA1 and TRPV2.
Sun MC, Fang K, Li ZX, Chu Y, Xu AP, Zhao ZY, Leng ZY, Zhang YW, Zhang ZH, Zhang L, Chen T, Xu MD., Free PMC Article | 07/23/2022 |
| Human Islet MicroRNA-200c Is Elevated in Type 2 Diabetes and Targets the Transcription Factor ETV5 to Reduce Insulin Secretion. | Human Islet MicroRNA-200c Is Elevated in Type 2 Diabetes and Targets the Transcription Factor ETV5 to Reduce Insulin Secretion.
Ofori JK, Karagiannopoulos A, Nagao M, Westholm E, Ramadan S, Wendt A, Esguerra JLS, Eliasson L., Free PMC Article | 02/26/2022 |
| Chromatin accessibility analysis identifies the transcription factor ETV5 as a suppressor of adipose tissue macrophage activation in obesity. | Chromatin accessibility analysis identifies the transcription factor ETV5 as a suppressor of adipose tissue macrophage activation in obesity.
Hu RD, Zhang W, Li L, Zuo ZQ, Ma M, Ma JF, Yin TT, Gao CY, Yang SH, Zhao ZB, Li ZJ, Qiao GB, Lian ZX, Qu K., Free PMC Article | 02/26/2022 |
| Biological and prognostic value of ETV5 in high-grade serous ovarian cancer. | Biological and prognostic value of ETV5 in high-grade serous ovarian cancer.
Zhang L, Fu R, Liu P, Wang L, Liang W, Zou H, Jia W, Tao L., Free PMC Article | 02/19/2022 |
| The role of E26 transformation-specific variant transcription factor 5 in colorectal cancer cell proliferation and cell cycle progression. | The role of E26 transformation-specific variant transcription factor 5 in colorectal cancer cell proliferation and cell cycle progression.
Peng Y, Feng H, Wang C, Song Z, Zhang Y, Liu K, Cheng X, Zhao R., Free PMC Article | 10/9/2021 |
| ETS variant transcription factor 5 and c-Myc cooperate in derepressing the human telomerase gene promoter via composite ETS/E-box motifs. | ETS variant transcription factor 5 and c-Myc cooperate in derepressing the human telomerase gene promoter via composite ETS/E-box motifs.
Zhang F, Wang S, Zhu J., Free PMC Article | 01/16/2021 |
| The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness. | The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness.
Mus LM, Lambertz I, Claeys S, Kumps C, Van Loocke W, Van Neste C, Umapathy G, Vaapil M, Bartenhagen C, Laureys G, De Wever O, Bexell D, Fischer M, Hallberg B, Schulte J, De Wilde B, Durinck K, Denecker G, De Preter K, Speleman F., Free PMC Article | 11/21/2020 |
| ETS Factor ETV5 Activates the Mutant Telomerase Reverse Transcriptase Promoter in Thyroid Cancer. | ETS Factor ETV5 Activates the Mutant Telomerase Reverse Transcriptase Promoter in Thyroid Cancer.
Bullock M, Lim G, Zhu Y, Åberg H, Kurdyukov S, Clifton-Bligh R. | 11/21/2020 |
| ETV5 links the FGFR3 and Hippo signalling pathways in bladder cancer. | ETV5 links the FGFR3 and Hippo signalling pathways in bladder cancer.
di Martino E, Alder O, Hurst CD, Knowles MA., Free PMC Article | 10/24/2020 |
| ETV5 enhanced follicular thyroid cancer cell proliferation, migration, and epithelial-mesenchymal transition through the PIK3CA signaling pathway | ETV5 overexpression contributes to tumor growth and progression of thyroid cancer through PIK3CA.
Meng D, Li Z, Ma X, Wu L, Fu L, Qin G. | 06/13/2020 |
| Study suggested that the transcription factor ETV5 could stimulate CRC malignancy and promote CRC angiogenesis by directly targeting PDGF-BB. | ETS variant 5 promotes colorectal cancer angiogenesis by targeting platelet-derived growth factor BB.
Cheng X, Jin Z, Ji X, Shen X, Feng H, Morgenlander W, Ou B, Wu H, Gao H, Ye F, Zhang Y, Peng Y, Liang J, Jiang Y, Zhang T, Qiu W, Lu X, Zhao R. | 11/2/2019 |
| exploration of the underlying mechanism demonstrated that ICAM3 not only binds to LFA-1 with its extracellular domain and structure protein ERM but also to lamellipodia with its intracellular domain which causes a tension that pulls cells apart (metastasis). | ICAM3 mediates tumor metastasis via a LFA-1-ICAM3-ERM dependent manner.
Shen W, Zhang X, Du R, Fan Y, Luo D, Bao Y, Yang W, Luo N, Luo Y, Zhao S. | 08/11/2018 |
| High Etv5 expression is associated with glioma. | Graph complexity analysis identifies an ETV5 tumor-specific network in human and murine low-grade glioma.
Pan Y, Duron C, Bush EC, Ma Y, Sims PA, Gutmann DH, Radunskaya A, Hardin J., Free PMC Article | 08/4/2018 |
| four oncogenic ETS (ERG, ETV1, ETV4, and ETV5), and no other ETS, interact with the Ewing's sarcoma breakpoint protein, EWS. | An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer.
Kedage V, Selvaraj N, Nicholas TR, Budka JA, Plotnik JP, Jerde TJ, Hollenhorst PC., Free PMC Article | 11/25/2017 |
| Novel ETV5 SNP rs7647305 is associated with childhood hypertension adjusted by obesity. | Two obesity susceptibility loci in LYPLAL1 and ETV5 independently associated with childhood hypertension in Chinese population.
Lv D, Zhou D, Zhang Y, Zhang S, Zhu YM. | 09/23/2017 |
| Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETV1, ETV4 and ETV5. | Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5.
Currie SL, Lau DKW, Doane JJ, Whitby FG, Okon M, McIntosh LP, Graves BJ., Free PMC Article | 07/22/2017 |
| the prostate cancer-related oncogenic E26 transformation-specific (ETS) transcription factors, ETV1, ETV4, and ETV5, were required for TAZ gene transcription in PC3 prostate cancer cells | ETS (E26 transformation-specific) up-regulation of the transcriptional co-activator TAZ promotes cell migration and metastasis in prostate cancer.
Liu CY, Yu T, Huang Y, Cui L, Hong W., Free PMC Article | 06/10/2017 |
| MiR-200b inhibition by transfection in MCF-7 markedly decreased miR-200b level, elevated ERM expression, and enhanced cell migration and invasion. MiR-200b overexpression in MDA-MB-231 obviously increased miR-200b level, reduced ERM expression, and weakened cell migration and invasion. | MicroRNA-200b Impacts Breast Cancer Cell Migration and Invasion by Regulating Ezrin-Radixin-Moesin.
Hong H, Yu H, Yuan J, Guo C, Cao H, Li W, Xiao C., Free PMC Article | 03/18/2017 |
| Resistin, a fat-derived secretory factor, promotes metastasis of MDA-MB-231 human breast cancer cells through ERM activation | Resistin, a fat-derived secretory factor, promotes metastasis of MDA-MB-231 human breast cancer cells through ERM activation.
Lee JO, Kim N, Lee HJ, Lee YW, Kim SJ, Park SH, Kim HS., Free PMC Article | 12/17/2016 |
| ERM proteins contribute toward accelerated CD44 shedding by MT1-MMP through ERM protein-mediated interactions between their cytoplasmic tails. | MT1-MMP recognition by ERM proteins and its implication in CD44 shedding.
Terawaki S, Kitano K, Aoyama M, Mori T, Hakoshima T. | 07/2/2016 |