| Preliminary exploration of SKA1 expression in lung adenocarcinoma and its clinical significance. | Preliminary exploration of SKA1 expression in lung adenocarcinoma and its clinical significance.
Zeng W, Chen Y, Liu J, An Z, Yan H, Sun T., Free PMC Article | 01/10/2024 |
| Integrated analysis of SKA1-related ceRNA network and SKA1 immunoassays in HCC: A study based on bioinformatic. | Integrated analysis of SKA1-related ceRNA network and SKA1 immunoassays in HCC: A study based on bioinformatic.
Zeng F, Xu Z, Zhuang P., Free PMC Article | 09/29/2023 |
| Hypoxia-induced lncRNA MRVI1-AS1 accelerates hepatocellular carcinoma progression by recruiting RNA-binding protein CELF2 to stabilize SKA1 mRNA. | Hypoxia-induced lncRNA MRVI1-AS1 accelerates hepatocellular carcinoma progression by recruiting RNA-binding protein CELF2 to stabilize SKA1 mRNA.
Tuo H, Liu R, Wang Y, Yang W, Liu Q., Free PMC Article | 04/5/2023 |
| Kinetochore-microtubule attachment in human cells is regulated by the interaction of a conserved motif of Ska1 with EB1. | Kinetochore-microtubule attachment in human cells is regulated by the interaction of a conserved motif of Ska1 with EB1.
Radhakrishnan RM, Kizhakkeduth ST, Nair VM, Ayyappan S, Lakshmi RB, Babu N, Prasannajith A, Umeda K, Vijayan V, Kodera N, Manna TK., Free PMC Article | 03/8/2023 |
| SKA1 is overexpressed in laryngocarcinoma and modulates cell growth via P53 signaling pathway. | SKA1 is overexpressed in laryngocarcinoma and modulates cell growth via P53 signaling pathway.
Li Z, Liu J, Peng H, Li C, Liu Y, Xie W., Free PMC Article | 03/3/2023 |
| SKA1 promotes tumor metastasis via SAFB-mediated transcription repression of DUSP6 in clear cell renal cell carcinoma. | SKA1 promotes tumor metastasis via SAFB-mediated transcription repression of DUSP6 in clear cell renal cell carcinoma.
Pu Y, Han J, Zhang M, Liu M, Abdusamat G, Liu H., Free PMC Article | 12/31/2022 |
| ETV5 overexpression promotes progression of esophageal squamous cell carcinoma by upregulating SKA1 and TRPV2. | ETV5 overexpression promotes progression of esophageal squamous cell carcinoma by upregulating SKA1 and TRPV2.
Sun MC, Fang K, Li ZX, Chu Y, Xu AP, Zhao ZY, Leng ZY, Zhang YW, Zhang ZH, Zhang L, Chen T, Xu MD., Free PMC Article | 07/23/2022 |
| miRNA-10a-5p inhibits cell metastasis in hepatocellular carcinoma via targeting SKA1. | miRNA-10a-5p inhibits cell metastasis in hepatocellular carcinoma via targeting SKA1.
Shen D, Zhao HY, Gu AD, Wu YW, Weng YH, Li SJ, Song JY, Gu XF, Qiu J, Zhao W. | 01/22/2022 |
| Circular RNA FAT atypical cadherin 1 (circFAT1)/microRNA-525-5p/spindle and kinetochore-associated complex subunit 1 (SKA1) axis regulates oxaliplatin resistance in breast cancer by activating the notch and Wnt signaling pathway. | Circular RNA FAT atypical cadherin 1 (circFAT1)/microRNA-525-5p/spindle and kinetochore-associated complex subunit 1 (SKA1) axis regulates oxaliplatin resistance in breast cancer by activating the notch and Wnt signaling pathway.
Yao Y, Li X, Cheng L, Wu X, Wu B., Free PMC Article | 11/13/2021 |
| Transcript levels of spindle and kinetochore-associated complex 1/3 as prognostic biomarkers correlated with immune infiltrates in hepatocellular carcinoma. | Transcript levels of spindle and kinetochore-associated complex 1/3 as prognostic biomarkers correlated with immune infiltrates in hepatocellular carcinoma.
Yu DC, Chen XY, Li X, Zhou HY, Yu DQ, Yu XL, Hu YC, Zhang RH, Zhang XB, Zhang K, An JD., Free PMC Article | 11/6/2021 |
| Prognostic value and functional bioinformatic analysis of spindle- and kinetochore-associated protein 1 in stage IIA esophageal squamous cell carcinoma. | Prognostic value and functional bioinformatic analysis of spindle- and kinetochore-associated protein 1 in stage IIA esophageal squamous cell carcinoma.
Hu D, Zhang M, Peng Z. | 12/5/2020 |
| SKA1 was significantly overexpressed in ESCC cells. | SKA1 overexpression is associated with the prognosis of esophageal squamous cell carcinoma and regulates cell proliferation and migration.
Hu D, Li Z, Li X, Fu H, Zhang M. | 08/1/2020 |
| our study has established the de novo MTX-resistant cell line SF-86 and identified SKA1 as a novel regulator of FPGS, playing a key role in the development of de novo MTX-resistance in osteosarcoma (OS). | SKA1 induces de novo MTX-resistance in osteosarcoma through inhibiting FPGS transcription.
Yu W, Min D, Lin F, Zheng S, Tang L, He A, Hu H, Shen Z. | 05/16/2020 |
| This study demonstrated that SKA1 enhanced pancreatic cancer aggressiveness by inhibiting G2/M arrest and regulating actin cytoskeleton organization via activating Cdc42. | SKA1 regulates actin cytoskeleton remodelling via activating Cdc42 and influences the migration of pancreatic ductal adenocarcinoma cells.
Li T, Liu X, Xu B, Wu W, Zang Y, Li J, Wei L, Qian Y, Xu H, Xie M, Wang Q, Wang L., Free PMC Article | 04/25/2020 |
| ZFAS1 promotes growth and metastasis of ccRCC via targeting miR-10a/SKA1 pathway. | Long non-coding RNA ZFAS1 promotes proliferation and metastasis of clear cell renal cell carcinoma via targeting miR-10a/SKA1 pathway.
Dong D, Mu Z, Wei N, Sun M, Wang W, Xin N, Shao Y, Zhao C. | 06/22/2019 |
| decreased neuronal cell SKA complex genes' expression levels affect neuronal cell viability and neurite development | The stress response HPA-axis hormone, glucocorticoid, reduces cellular SKA complex gene expression.
Zhao J, Zhang P, He Z, Chen S, Golden T, Li L, Li M, Wu N. | 11/3/2018 |
| High SKA1 expression is associated with early recurrence and progression in patients with NMIBC, indicating SKA1 may serve as a promising prognostic biomarker for this disease. | High expression of spindle and kinetochore- associated protein 1 predicts early recurrence and progression of non-muscle invasive bladder cancer.
Jiang S, Tian F, Wang Q, Cheng W, Wang L, Wang Y, Sun W. | 10/20/2018 |
| End-binding protein 1 (EB1) depletion results in a significant reduction of spindle and kinetochore-associated protein 1 (Ska1) recruitment onto microtubules and defects in mitotic chromosome alignment. | EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice.
Thomas GE, Bandopadhyay K, Sutradhar S, Renjith MR, Singh P, Gireesh KK, Simon S, Badarudeen B, Gupta H, Banerjee M, Paul R, Mitra J, Manna TK., Free PMC Article | 09/29/2018 |
| SKA1 might be a promising target for cancer gene therapy in human ACC. | Knockdown of SKA1 gene inhibits cell proliferation and metastasis in human adenoid cystic carcinoma.
Zhao LJ, Yang HL, Li KY, Gao YH, Dong K, Liu ZH, Wang LX, Zhang B. | 02/24/2018 |
| Results show that SKA1 expression is regulated by mir-10a. Its knockdown inhibits migration and invasion in renal cell carcinoma cells. | Regulation of spindle and kinetochore-associated protein 1 by antitumor miR-10a-5p in renal cell carcinoma.
Arai T, Okato A, Kojima S, Idichi T, Koshizuka K, Kurozumi A, Kato M, Yamazaki K, Ishida Y, Naya Y, Ichikawa T, Seki N., Free PMC Article | 10/7/2017 |
| Study indicated that hypoxia mediated downregulation of SKA1 expression increased the chemotherapy resistance in human osteosarcoma cells. | Hypoxia promotes chemotherapy resistance by down-regulating SKA1 gene expression in human osteosarcoma.
Ma Q, Zhang Y, Liu T, Jiang K, Wen Y, Fan Q, Qiu X., Free PMC Article | 09/30/2017 |
| Kinetochores mature through Ska1/ska2/Ska3 complex recruitment and this is required for improved load-bearing capacity and silencing of the spindle assembly checkpoint. | Congressing kinetochores progressively load Ska complexes to prevent force-dependent detachment.
Auckland P, Clarke NI, Royle SJ, McAinsh AD., Free PMC Article | 09/16/2017 |
| In conclusion, our findings suggest that spindle and kinetochore-associated protein 1 could serve as a potential therapeutic target in prostate cancer patients. | Overexpression of spindle and kinetochore-associated protein 1 contributes to the progression of prostate cancer.
Wang K, Sun J, Teng J, Yu Y, Zhong D, Fan Y. | 07/15/2017 |
| expression positively associated with tumor-node-metastasis stage and recurrence of salivary adenoid cystic carcinoma | Expression of SKA1 and MMP-9 in primary salivary adenoid cystic carcinoma: Correlation with tumor progression and patient prognosis.
Zhao L, Jiang L, Du P, Zhang D, Liu Z, Li K, Zhang B. | 02/18/2017 |
| Thus, the Ska complex, specifically the Ska1 C-terminal domain, recruits PP1 to kinetochores to oppose spindle checkpoint signaling kinases and promote anaphase onset. | The human SKA complex drives the metaphase-anaphase cell cycle transition by recruiting protein phosphatase 1 to kinetochores.
Sivakumar S, Janczyk PŁ, Qu Q, Brautigam CA, Stukenberg PT, Yu H, Gorbsky GJ., Free PMC Article | 01/14/2017 |