| Signals from the TAFA4-PTEN-PU.1 axis alleviate nasal allergy by modulating the expression of FcepsilonRI in mast cells. | Signals from the TAFA4-PTEN-PU.1 axis alleviate nasal allergy by modulating the expression of FcεRI in mast cells.
Zhou C, Li M, Liu Y, Wang X, Zhang S, Guan L, Hong J, Zhou W, Wu G, Diao W, Huang Q, Yang P., Free PMC Article | 03/11/2023 |
| The Crosstalk between FcepsilonRI and Sphingosine Signaling in Allergic Inflammation. | The Crosstalk between FcεRI and Sphingosine Signaling in Allergic Inflammation.
Jo H, Shim K, Jeoung D., Free PMC Article | 12/10/2022 |
| FcER1: A Novel Molecule Implicated in the Progression of Human Diabetic Kidney Disease. | FcER1: A Novel Molecule Implicated in the Progression of Human Diabetic Kidney Disease.
Sur S, Nguyen M, Boada P, Sigdel TK, Sollinger H, Sarwal MM., Free PMC Article | 02/19/2022 |
| Genetic association study of CTLA4 and FCepsilonRIalpha polymorphisms in asthmatic patients in the southwestern region of Iran. | Genetic association study of CTLA4 and FCεRIα polymorphisms in asthmatic patients in the southwestern region of Iran.
Roshanizadeh Z, Ghandil P, Khodadadi A, Tavakol H, Kambiz AA, Ghadiri A. | 01/15/2022 |
| Inverse association of FCER1A allergy variant in monocytes and plasmacytoid dendritic cells. | Inverse association of FCER1A allergy variant in monocytes and plasmacytoid dendritic cells.
Andiappan AK, Puan KJ, Lee B, Yeow PT, Yusof N, Merid SK, Kumar D, Lum J, Foo S, Koh G, Poidinger M, Zolezzi F, eQTLGen Consortium, BIOS Consortium, Wang Y, Melén E, Rotzschke O. | 11/22/2021 |
| Interaction between functional polymorphisms in FCER1A and TLR2 and the severity of atopic dermatitis. | Interaction between functional polymorphisms in FCER1A and TLR2 and the severity of atopic dermatitis.
Potaczek DP, Przytulska-Szczerbik A, Bazan-Socha S, Nastałek M, Wojas-Pelc A, Okumura K, Nishiyama C, Jurczyszyn A, Undas A, Wypasek E. | 08/28/2021 |
| Prediction of prognostic signatures in triple-negative breast cancer based on the differential expression analysis via NanoString nCounter immune panel. | Prediction of prognostic signatures in triple-negative breast cancer based on the differential expression analysis via NanoString nCounter immune panel.
Lim GB, Kim YA, Seo JH, Lee HJ, Gong G, Park SH., Free PMC Article | 04/24/2021 |
| FcepsilonRI Signaling in the Modulation of Allergic Response: Role of Mast Cell-Derived Exosomes. | FcεRI Signaling in the Modulation of Allergic Response: Role of Mast Cell-Derived Exosomes.
Lecce M, Molfetta R, Milito ND, Santoni A, Paolini R., Free PMC Article | 02/20/2021 |
| Relevance of the Basophil High-Affinity IgE Receptor in Chronic Urticaria: Clinical Experience from a Tertiary Care Institution. | Relevance of the Basophil High-Affinity IgE Receptor in Chronic Urticaria: Clinical Experience from a Tertiary Care Institution.
Deza G, March-Rodríguez A, Sánchez S, Ribas-Llauradó C, Soto D, Pujol RM, Gimeno R, Giménez-Arnau AM. | 08/22/2020 |
| FCER1A (rs7549785) and possibly POLR3G (rs7712322) are shown to be associated with peginterferon alfa-2a response in adult patients with chronic hepatitis B. | Genetic variation in FCER1A predicts peginterferon alfa-2a-induced hepatitis B surface antigen clearance in East Asian patients with chronic hepatitis B.
Wei L, Pavlovic V, Bansal AT, Chen X, Foster GR, He H, Kao JH, Lampertico P, Liaw YF, Motoc A, Papatheodoridis GV, Piratvisuth T, Plesniak R, Wat C. | 07/25/2020 |
| Circulating IgG to FcepsilonRIa was detected in 52.5% of CSU patients, including 83.3% of ASST-positive patients and 78.3% of APST-positive patients. Circulating IgG to FcepsilonRIa involved in the pathogenic mechanisms of CSU. | Assessment of circulating FCεRIa in Chronic Spontaneous Urticaria patients and its correlation with clinical and immunological variables.
Baioumy SA, Esawy MM, Shabana MA. | 06/15/2019 |
| Patient stratification revealed a significant association (P < 0.05) of rs2427827 SNP with high IgE level Chronic Rhinosinusitis with Nasal Polyposis (CRSwNP) patients. Nonetheless, we found no SNP associated with low serum IgE level patients. SNP (rs2427827) in the FcvarepsilonR1alpha gene region and high IgE levels may confer susceptibility to CRSwNP in north Indian population. | FcɛR1α gene polymorphism shows association with high IgE and anti-FcɛR1α in Chronic Rhinosinusitis with Nasal Polyposis.
Dar SA, Rai G, Ansari MA, Akhter N, Gupta N, Sharma S, Haque S, Ramachandran VG, Wahid M, Rudramurthy SM, Chakrabarti A, Das S. | 12/22/2018 |
| Data show that each IgE Fc is targeted by two single-domain antibodies (sdabs) having an epitope largely distinct from the FcepsilonRI binding site but overlapping significantly with the CD23-binding site. | Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction.
Jabs F, Plum M, Laursen NS, Jensen RK, Mølgaard B, Miehe M, Mandolesi M, Rauber MM, Pfützner W, Jakob T, Möbs C, Andersen GR, Spillner E., Free PMC Article | 03/10/2018 |
| Autoreactive CD4(+) T cells that target FcepsilonRIalpha were detected in most subjects with chronic spontaneous urticaria, with a cytokine secretion profile more typical of a TH1-cell response. Our findings suggest that measurement of T-cell as well as autoantibody responses to FcepsilonRIalpha could improve diagnostic accuracy in subjects with chronic spontaneous urticaria . | Autoreactive T cells in chronic spontaneous urticaria target the IgE Fc receptor Iα subunit.
Auyeung P, Mittag D, Hodgkin PD, Harrison LC. | 07/1/2017 |
| Our results suggest that IL13 rs20541, IL4 rs2243250, ADRB2 rs1042713, and FCER1B rs569108, four SNPs with significant sole effect on asthma, interact to confer a higher risk for the disease in Chinese Han children. | Four-locus gene interaction between IL13, IL4, FCER1B, and ADRB2 for asthma in Chinese Han children.
Hua L, Zuo XB, Bao YX, Liu QH, Li JY, Lv J, Fang DZ, Lin Q, Bao J, Ji RX. | 12/17/2016 |
| F-AFE containing anti-allergic phytochemicals, including arctigenin, inhibited the activation of the FceRI receptor induced by the antigenIgE complex | Inhibitory effect of fermented Arctium lappa fruit extract on the IgE-mediated allergic response in RBL‑2H3 cells.
Yoo JM, Yang JH, Yang HJ, Cho WK, Ma JY. | 10/29/2016 |
| IgG2 and IgG3 are involved in recruiting CD32 to inhibit activation of FcepsilonRI in human basophils. | Parameters determining the efficacy of CD32 to inhibit activation of FcεRI in human basophils.
MacGlashan D Jr, Hamilton RG., Free PMC Article | 09/3/2016 |
| Asthmatics with reduced lung function had a higher frequency of Lin(-) CD34(hi) CD117(int/hi) Fc epsilon RI(+) blood mast cell progenitors than asthmatics with normal lung function. | Lin- CD34hi CD117int/hi FcεRI+ cells in human blood constitute a rare population of mast cell progenitors.
Dahlin JS, Malinovschi A, Öhrvik H, Sandelin M, Janson C, Alving K, Hallgren J., Free PMC Article | 06/28/2016 |
| SNPs of FcepsilonR1alpha promoter region may be used as disease markers for IgE-mediated allergic inflammation caused by Dermatophagoides pteronyssinus. | An Exploratory Pilot Study of Genetic Marker for IgE-Mediated Allergic Diseases with Expressions of FcεR1α and Cε.
Liao EC, Chang CY, Hsieh CW, Yu SJ, Yin SC, Tsai JJ., Free PMC Article | 04/30/2016 |
| FcepsilonRI alpha-chain is an activating platelet endothelium aggregation receptor 1 (PEAR1) ligand. | A Human Platelet Receptor Protein Microarray Identifies the High Affinity Immunoglobulin E Receptor Subunit α (FcεR1α) as an Activating Platelet Endothelium Aggregation Receptor 1 (PEAR1) Ligand.
Sun Y, Vandenbriele C, Kauskot A, Verhamme P, Hoylaerts MF, Wright GJ., Free PMC Article | 02/6/2016 |
| Tetraspanin CD151 Is a Negative Regulator of FcepsilonRI-Mediated Mast Cell Activation | Tetraspanin CD151 Is a Negative Regulator of FcεRI-Mediated Mast Cell Activation.
Abdala-Valencia H, Bryce PJ, Schleimer RP, Wechsler JB, Loffredo LF, Cook-Mills JM, Hsu CL, Berdnikovs S., Free PMC Article | 11/28/2015 |
| These data suggest that rs2298805 might be associated with risk for Chronic urticaria and the therapeutic efficacy of nonsedating H1-antihistamines in Chinese patients | Association of FCER1A genetic polymorphisms with risk for chronic spontaneous urticaria and efficacy of nonsedating H1-antihistamines in Chinese patients.
Guo A, Zhu W, Zhang C, Wen S, Chen X, Chen M, Zhang J, Su J, Chen W, Zhao Y, Yan S, He Y, Liu Z, Zhou H, Chen X, Li J. | 11/14/2015 |
| FCER2 polymorphism rs3760687 affects moderately elevated total serum IgE levels, especially in the absence of homozygosity for the risk allele of FCER1A SNP rs2427837. | A role of FCER1A and FCER2 polymorphisms in IgE regulation.
Sharma V, Michel S, Gaertner V, Franke A, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Frischer T, Genuneit J, Potaczek DP, Kabesch M. | 09/13/2014 |
| Data indicate that antigen (Ag) targeting to FcepsilonRI inhibits the development of Ag-specific T cell immunity and induces T cell tolerance. | Antigen-conjugated human IgE induces antigen-specific T cell tolerance in a humanized mouse model.
Baravalle G, Greer AM, LaFlam TN, Shin JS., Free PMC Article | 06/14/2014 |
| FCER1A expressing dendritic cells and monocytes but not basophils, significantly contribute to serum hIgE clearance. | Serum IgE clearance is facilitated by human FcεRI internalization.
Greer AM, Wu N, Putnam AL, Woodruff PG, Wolters P, Kinet JP, Shin JS., Free PMC Article | 05/10/2014 |