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    FGF9 fibroblast growth factor 9 [ Homo sapiens (human) ]

    Gene ID: 2254, updated on 6-May-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Upregulation of FGF9 and NOVA1 in cancer-associated fibroblasts promotes cell proliferation, invasion and migration of triple negative breast cancer.

    Upregulation of FGF9 and NOVA1 in cancer-associated fibroblasts promotes cell proliferation, invasion and migration of triple negative breast cancer.
    Zhang B, Liu Y, Yu J, Lin X.

    05/3/2024
    FGF9 Promotes Expression of HAS2 in Palatal Elevation via the Wnt/beta-Catenin/TCF7L2 Pathway.

    FGF9 Promotes Expression of HAS2 in Palatal Elevation via the Wnt/β-Catenin/TCF7L2 Pathway.
    Sun Y, Ying X, Li R, Weng M, Shi J, Chen Z., Free PMC Article

    11/19/2022
    Fibroblast growth factor-9 expression in airway epithelial cells amplifies the type I interferon response and alters influenza A virus pathogenesis.

    Fibroblast growth factor-9 expression in airway epithelial cells amplifies the type I interferon response and alters influenza A virus pathogenesis.
    Hiller BE, Yin Y, Perng YC, de Araujo Castro Í, Fox LE, Locke MC, Monte KJ, López CB, Ornitz DM, Lenschow DJ., Free PMC Article

    07/2/2022
    Downregulated exosome-associated gene FGF9 as a novel diagnostic and prognostic target for ovarian cancer and its underlying roles in immune regulation.

    Downregulated exosome-associated gene FGF9 as a novel diagnostic and prognostic target for ovarian cancer and its underlying roles in immune regulation.
    Xu Z, Cai Y, Liu W, Kang F, He Q, Hong Q, Zhang W, Li J, Yan Y, Peng J., Free PMC Article

    04/30/2022
    Upregulation of FGF9 in Lung Adenocarcinoma Transdifferentiation to Small Cell Lung Cancer.

    Upregulation of FGF9 in Lung Adenocarcinoma Transdifferentiation to Small Cell Lung Cancer.
    Ishioka K, Yasuda H, Hamamoto J, Terai H, Emoto K, Kim TJ, Hirose S, Kamatani T, Mimaki S, Arai D, Ohgino K, Tani T, Masuzawa K, Manabe T, Shinozaki T, Mitsuishi A, Ebisudani T, Fukushima T, Ozaki M, Ikemura S, Kawada I, Naoki K, Nakamura M, Ohtsuka T, Asamura H, Tsuchihara K, Hayashi Y, Hegab AE, Kobayashi SS, Kohno T, Watanabe H, Ornitz DM, Betsuyaku T, Soejima K, Fukunaga K.

    01/29/2022
    miR4865p suppresses gastric cancer cell growth and migration through downregulation of fibroblast growth factor 9.

    miR‑486‑5p suppresses gastric cancer cell growth and migration through downregulation of fibroblast growth factor 9.
    Wei W, Liu C, Yao R, Tan Q, Wang Q, Tian H., Free PMC Article

    01/22/2022
    A novel heterozygous variant in FGF9 associated with previously unreported features of multiple synostosis syndrome 3.

    A novel heterozygous variant in FGF9 associated with previously unreported features of multiple synostosis syndrome 3.
    Thuresson AC, Croft B, Hailer YD, Liminga G, Arvidsson CG, Harley VR, Stattin EL., Free PMC Article

    11/27/2021
    Identification of the third FGF9 variant in a girl with multiple synostosis-comparison of the genotype:phenotype of FGF9 variants in humans and mice.

    Identification of the third FGF9 variant in a girl with multiple synostosis-comparison of the genotype:phenotype of FGF9 variants in humans and mice.
    Sentchordi-Montané L, Diaz-Gonzalez F, Cátedra-Vallés EV, Heath KE.

    11/27/2021
    Downregulation of miR-499a-5p Predicts a Poor Prognosis of Patients With Non-Small Cell Lung Cancer and Restrains the Tumorigenesis by Targeting Fibroblast Growth Factor 9.

    Downregulation of miR-499a-5p Predicts a Poor Prognosis of Patients With Non-Small Cell Lung Cancer and Restrains the Tumorigenesis by Targeting Fibroblast Growth Factor 9.
    Zhao L, Jiang P, Zheng H, Chen P, Yang M., Free PMC Article

    11/6/2021
    Fgf9 Negatively Regulates Bone Mass by Inhibiting Osteogenesis and Promoting Osteoclastogenesis Via MAPK and PI3K/AKT Signaling.

    Fgf9 Negatively Regulates Bone Mass by Inhibiting Osteogenesis and Promoting Osteoclastogenesis Via MAPK and PI3K/AKT Signaling.
    Tang L, Wu M, Lu S, Zhang H, Shen Y, Shen C, Liang H, Ge H, Ding X, Wang Z.

    09/18/2021
    Effect of lentivirus-mediated miR-182 targeting FGF9 on hallux valgus.

    Effect of lentivirus-mediated miR-182 targeting FGF9 on hallux valgus.
    Zhang WL, Zhao DY, Zhao W, Cui Y, Li Q, Zhang ZY., Free PMC Article

    09/18/2021
    DJ-1 promotes epithelial-to-mesenchymal transition via enhancing FGF9 expression in colorectal cancer.

    DJ-1 promotes epithelial-to-mesenchymal transition via enhancing FGF9 expression in colorectal cancer.
    Li L, Zhang C, Li Y, Zhang Y, Lei Y., Free PMC Article

    08/28/2021
    Expression and function of FGF9 in the hypertrophied ligamentum flavum of lumbar spinal stenosis patients.

    Expression and function of FGF9 in the hypertrophied ligamentum flavum of lumbar spinal stenosis patients.
    Habibi H, Suzuki A, Hayashi K, Salimi H, Terai H, Hori Y, Tamai K, Orita K, Ohyama S, Yabu A, Maruf MH, Nakamura H.

    08/7/2021
    The long noncoding RNA LINC01140/miR-140-5p/FGF9 axis modulates bladder cancer cell aggressiveness and macrophage M2 polarization.

    The long noncoding RNA LINC01140/miR-140-5p/FGF9 axis modulates bladder cancer cell aggressiveness and macrophage M2 polarization.
    Wu S, Xu R, Zhu X, He H, Zhang J, Zeng Q, Wang Y, Zhao X., Free PMC Article

    05/29/2021
    The correlation between adiponectin and FGF9 in depression disorder.

    The correlation between adiponectin and FGF9 in depression disorder.
    Wang XQ, Li WH, Tang YH, Wu LF, Zeng GR, Wang YH, Cheng ZN, Jiang DJ.

    05/29/2021
    circCCND1 Regulates Oxidative Stress and FGF9 to Enhance Chemoresistance of Non-Small Cell Lung Cancer via Sponging miR-187-3p.

    circCCND1 Regulates Oxidative Stress and FGF9 to Enhance Chemoresistance of Non-Small Cell Lung Cancer via Sponging miR-187-3p.
    Geng J, Yang K.

    05/15/2021
    miR-140-5p targeted FGF9 and inhibited the cell growth of laryngeal squamous cell carcinoma.

    miR-140-5p targeted FGF9 and inhibited the cell growth of laryngeal squamous cell carcinoma.
    Wang Y, Huang Q, Li F.

    02/27/2021
    FGF9 promotes mouse spermatogonial stem cell proliferation mediated by p38 MAPK signalling.

    FGF9 promotes mouse spermatogonial stem cell proliferation mediated by p38 MAPK signalling.
    Yang F, Whelan EC, Guan X, Deng B, Wang S, Sun J, Avarbock MR, Wu X, Brinster RL., Free PMC Article

    01/23/2021
    Fibroblast Growth Factor 9 is expressed by activated hepatic stellate cells and promotes progression of hepatocellular carcinoma.

    Fibroblast Growth Factor 9 is expressed by activated hepatic stellate cells and promotes progression of hepatocellular carcinoma.
    Seitz T, Freese K, Dietrich P, Thasler WE, Bosserhoff A, Hellerbrand C., Free PMC Article

    11/28/2020
    MiR-187 suppresses non-small-cell lung cancer cell proliferation by targeting FGF9.

    MiR-187 suppresses non-small-cell lung cancer cell proliferation by targeting FGF9.
    Liang Z, Xu J, Ma Z, Li G, Zhu W., Free PMC Article

    10/3/2020
    Fibroblast growth factor 9 (FGF9) inhibits myogenic differentiation of C2C12 and human muscle cells.

    Fibroblast growth factor 9 (FGF9) inhibits myogenic differentiation of C2C12 and human muscle cells.
    Huang J, Wang K, Shiflett LA, Brotto L, Bonewald LF, Wacker MJ, Dallas SL, Brotto M., Free PMC Article

    08/22/2020
    This study shows that adipose-derived FGF9 play as an inhibitory role in the browning of white adipocytes.

    FGF9 inhibits browning program of white adipocytes and associates with human obesity.
    Sun Y, Wang R, Zhao S, Li W, Liu W, Tang L, Wang Z, Wang W, Liu R, Ning G, Wang J, Hong J.

    06/20/2020
    FGF9 acts in concert with VSX2 to promote NR differentiation in hiPSC-OVs and has potential to be used to manipulate early retinogenesis and mitigate ocular defects caused by functional loss of VSX2 activity

    The Role of FGF9 in the Production of Neural Retina and RPE in a Pluripotent Stem Cell Model of Early Human Retinal Development.
    Gamm DM, Clark E, Capowski EE, Singh R., Free PMC Article

    03/21/2020
    FGF9-induced ovarian cancer cell invasion involves VEGFA/VEGFR2 augmentation by virtue of ETS1 upregulation and metabolic reprogramming.

    FGF9-induced ovarian cancer cell invasion involves VEGF-A/VEGFR2 augmentation by virtue of ETS1 upregulation and metabolic reprogramming.
    Bhattacharya R, Ray Chaudhuri S, Roy SS.

    10/12/2019
    MiR-219a-5p plays a crucial role in the development of acquired drug resistance to DDP in NSCLC cells by targeting FGF9.

    MiR-219a-5p enhances cisplatin sensitivity of human non-small cell lung cancer by targeting FGF9.
    Rao C, Miao X, Zhao G, Zhang C, Shen H, Dong C, Yang M.

    08/31/2019
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