| MicroRNA-92a-CPEB3 axis protects neurons against inflammatory neurodegeneration. | MicroRNA-92a-CPEB3 axis protects neurons against inflammatory neurodegeneration.
Winkler I, Engler JB, Vieira V, Bauer S, Liu YH, Di Liberto G, Grochowska KM, Wagner I, Bier J, Bal LC, Rothammer N, Meurs N, Egervari K, Schattling B, Salinas G, Kreutz MR, Huang YS, Pless O, Merkler D, Friese MA., Free PMC Article | 03/13/2024 |
| Phase separation modulates the functional amyloid assembly of human CPEB3. | Phase separation modulates the functional amyloid assembly of human CPEB3.
Ramírez de Mingo D, López-García P, Vaquero ME, Hervás R, Laurents DV, Carrión-Vázquez M. | 01/3/2024 |
| CPEB3, an RNA-Binding Protein, Modulates the Behavior of Endometriosis-Derived Stromal Cells via Regulating CXCL12. | CPEB3, an RNA-Binding Protein, Modulates the Behavior of Endometriosis-Derived Stromal Cells via Regulating CXCL12.
Wang J, Wu H, Wang X, Zhao X, Sun L, Cheng Y, Jiang X, Li J, Zhang G. | 06/18/2022 |
| Conformational dynamics in the disordered region of human CPEB3 linked to memory consolidation. | Conformational dynamics in the disordered region of human CPEB3 linked to memory consolidation.
Ramírez de Mingo D, Pantoja-Uceda D, Hervás R, Carrión-Vázquez M, Laurents DV., Free PMC Article | 06/11/2022 |
| CPEB3 overexpression caused by miR-106b-5p inhibition inhibits esophageal carcinoma in-vitro progression and metastasis. | CPEB3 overexpression caused by miR-106b-5p inhibition inhibits esophageal carcinoma in-vitro progression and metastasis.
Wang H, Peng D, Gan M, He Z, Kuang Y. | 05/7/2022 |
| MiR-20b-5p promotes hepatocellular carcinoma cell proliferation, migration and invasion by down-regulating CPEB3. | MiR-20b-5p promotes hepatocellular carcinoma cell proliferation, migration and invasion by down-regulating CPEB3.
Li Z, Wu L, Tan W, Zhang K, Lin Q, Zhu J, Tu C, Lv X, Jiang C. | 01/15/2022 |
| LINC00641 hinders the progression of cervical cancer by targeting miR-378a-3p/CPEB3. | LINC00641 hinders the progression of cervical cancer by targeting miR-378a-3p/CPEB3.
Zhang Y, Yu R, Li L. | 08/28/2021 |
| Decreased Expression of CPEB3 Predicts a Poor Prognosis in Patients with Melanoma: A Study Based on TCGA Data. | Decreased Expression of CPEB3 Predicts a Poor Prognosis in Patients with Melanoma: A Study Based on TCGA Data.
Zhang X, Liang Y., Free PMC Article | 05/29/2021 |
| CPEB3-mediated MTDH mRNA translational suppression restrains hepatocellular carcinoma progression. | CPEB3-mediated MTDH mRNA translational suppression restrains hepatocellular carcinoma progression.
Zhang H, Zou C, Qiu Z, E F, Li Q, Chen M, Wang D, Tan Q, Yin W, Matunda C, Wang H, Zhang Y, Zhan C, Wang C, Wu Y, Xuan X, Wang Y, Zou C, Lv G, Gao X., Free PMC Article | 05/15/2021 |
| linc00968 inhibits the tumorigenesis and metastasis of lung adenocarcinoma via serving as a ceRNA against miR-9-5p and increasing CPEB3. | linc00968 inhibits the tumorigenesis and metastasis of lung adenocarcinoma via serving as a ceRNA against miR-9-5p and increasing CPEB3.
Tang H, Han X, Feng Y, Hao Y., Free PMC Article | 05/1/2021 |
| CPEB3 functions as a tumor suppressor in colorectal cancer via JAK/STAT signaling. | CPEB3 functions as a tumor suppressor in colorectal cancer via JAK/STAT signaling.
Fang Y, Zhong Q, Wang Y, Gu C, Liu S, Li A, Yan Q., Free PMC Article | 04/24/2021 |
| CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling. | CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling.
Zhong Q, Fang Y, Lai Q, Wang S, He C, Li A, Liu S, Yan Q., Free PMC Article | 04/3/2021 |
| MiR-224 Executes a Tumor Accelerative Role during Hepatocellular Carcinoma Malignancy by Targeting Cytoplasmic Polyadenylation Element-Binding Protein 3. | MiR-224 Executes a Tumor Accelerative Role during Hepatocellular Carcinoma Malignancy by Targeting Cytoplasmic Polyadenylation Element-Binding Protein 3.
Miao K, Liu SD, Huang WX, Dong H. | 02/6/2021 |
| miRNA-301b-3p accelerates migration and invasion of high-grade ovarian serous tumor via targeting CPEB3/EGFR axis. | miRNA-301b-3p accelerates migration and invasion of high-grade ovarian serous tumor via targeting CPEB3/EGFR axis.
Liu F, Zhang G, Lv S, Wen X, Liu P. | 09/19/2020 |
| NFE2L1 and NFE2L3 Complementarily Maintain Basal Proteasome Activity in Cancer Cells through CPEB3-Mediated Translational Repression. | NFE2L1 and NFE2L3 Complementarily Maintain Basal Proteasome Activity in Cancer Cells through CPEB3-Mediated Translational Repression.
Waku T, Katayama H, Hiraoka M, Hatanaka A, Nakamura N, Tanaka Y, Tamura N, Watanabe A, Kobayashi A., Free PMC Article | 08/22/2020 |
| Here, we performed deep mutational scanning of self-cleaving CPEB3 ribozyme by error-prone PCR and showed that a library of <5 x 104 single-to-triple mutants is sufficient to infer 25 of 26 base pairs including non-nested, nonhelical, and noncanonical base pairs with both sensitivity and precision at 96%. | Accurate inference of the full base-pairing structure of RNA by deep mutational scanning and covariation-induced deviation of activity.
Zhang Z, Xiong P, Zhang T, Wang J, Zhan J, Zhou Y., Free PMC Article | 03/21/2020 |
| SUMO1P3 was upregulated in colorectal cancer tissues and cells and bore prognostic significance. SUMO1P3 epigenetically silenced CPEB3 through EZH2. SUMO1P3 regulated proliferation and apoptosis through CPEB3. | LncRNA SUMO1P3 promotes proliferation and inhibits apoptosis in colorectal cancer by epigenetically silencing CPEB3.
Lin H, Guo Q, Lu S, Chen J, Li X, Gong M, Tang L, Wen J. | 12/28/2019 |
| Overexpression of miR-452-3p promoted cell proliferation and mobility and suppressed apoptosis. MiR-452-3p enhanced EGFR and phosphorylated AKT (pAKT) expression but inhibited p21 expression level. MiR-452-3p promoted hepatocellular carcinoma (HCC)cell proliferation and mobility by directly targeting the CPEB3/EGFR axis | Mir-452-3p: A Potential Tumor Promoter That Targets the CPEB3/EGFR Axis in Human Hepatocellular Carcinoma.
Tang H, Zhang J, Yu Z, Ye L, Li K, Ding F, Feng X, Meng W., Free PMC Article | 11/3/2018 |
| Data show that the expression of cytoplasmic polyadenylation element binding protein 3 (CPEB3) positively correlated with tumor progression and malignancy but negatively correlated with protein phosphorylation in the alternatively spliced region. | Altered splicing leads to reduced activation of CPEB3 in high-grade gliomas.
Skubal M, Gielen GH, Waha A, Gessi M, Kaczmarczyk L, Seifert G, Freihoff D, Freihoff J, Pietsch T, Simon M, Theis M, Steinhäuser C, Waha A., Free PMC Article | 01/20/2018 |
| Expression of miR-26a and miR-29a was significantly down regulated in leukoplakia and cancer tissues but up regulated in lichen planus tissues. Expression of target genes such as, ADAMTS7, ATP1B1, COL4A2, CPEB3, CDK6, DNMT3a and PI3KR1 was significantly down regulated in at least two of three disease types with respect to normal tissues. | MicroRNA and target gene expression based clustering of oral cancer, precancer and normal tissues.
Roy R, Singh R, Chattopadhyay E, Ray A, Sarkar N, Aich R, Paul RR, Pal M, Roy B. | 01/28/2017 |
| Data show that EGF receptor (EGFR) is involved in the microRNA miR-107 pathogenesis of hepatocellular carcinoma (HCC) through cytoplasmic polyadenylation element binding protein 3 (CPEB3). | MicroRNA-107: a novel promoter of tumor progression that targets the CPEB3/EGFR axis in human hepatocellular carcinoma.
Zou CD, Zhao WM, Wang XN, Li Q, Huang H, Cheng WP, Jin JF, Zhang H, Wu MJ, Tai S, Zou CX, Gao X., Free PMC Article | 11/5/2016 |
| Data suggest that the RNA recognition motif (RRM) domain of CPEB3 (as a soluble peptide fragment) exhibits protein conformation distinct from those of the canonical RRM domain. | Novel RNA recognition motif domain in the cytoplasmic polyadenylation element binding protein 3.
Tsuda K, Kuwasako K, Nagata T, Takahashi M, Kigawa T, Kobayashi N, Güntert P, Shirouzu M, Yokoyama S, Muto Y. | 10/31/2015 |
| cleavage of CPEB3 by NMDA-activated calpain 2 accounts for the activity-related translation of CPEB3-targeted RNAs | Calpain 2 activated through N-methyl-D-aspartic acid receptor signaling cleaves CPEB3 and abrogates CPEB3-repressed translation in neurons.
Wang CF, Huang YS., Free PMC Article | 10/20/2012 |
| Together, these results indicate that Tob mediates the recruitment of Caf1 to the target of CPEB3 and elicits deadenylation and decay of the mRNA. | Anti-proliferative protein Tob negatively regulates CPEB3 target by recruiting Caf1 deadenylase.
Hosoda N, Funakoshi Y, Hirasawa M, Yamagishi R, Asano Y, Miyagawa R, Ogami K, Tsujimoto M, Hoshino S., Free PMC Article | 06/18/2011 |
| Secondary structure determination and native gel analyses reveal that the cleaved population of the CPEB3 ribozyme has a single, secondary structure that closely resembles the HDV ribozyme | The human HDV-like CPEB3 ribozyme is intrinsically fast-reacting.
Chadalavada DM, Gratton EA, Bevilacqua PC., Free PMC Article | 07/26/2010 |