| Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3' UTR of FAIM2. | Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3' UTR of FAIM2.
Littleton SH, Trang KB, Volpe CM, Cook K, DeBruyne N, Maguire JA, Weidekamp MA, Hodge KM, Boehm K, Lu S, Chesi A, Bradfield JP, Pippin JA, Anderson SA, Wells AD, Pahl MC, Grant SFA., Free PMC Article | 05/29/2024 |
| miR-127-5p regulates FAIM2-mediated cell apoptosis and participates in cerebral ischemia-reperfusion injury. | miR-127-5p regulates FAIM2-mediated cell apoptosis and participates in cerebral ischemia-reperfusion injury.
Hu T, Lin Y. | 03/14/2024 |
| FAIM2 is correlated with metastasis of medulloblastoma through bioinformatics analysis. | FAIM2 is correlated with metastasis of medulloblastoma through bioinformatics analysis.
Zhou X, Zhao H., Free PMC Article | 10/20/2023 |
| Antiapoptotic Protein FAIM2 is targeted by miR-3202, and DUX4 via TRIM21, leading to cell death and defective myogenesis. | Antiapoptotic Protein FAIM2 is targeted by miR-3202, and DUX4 via TRIM21, leading to cell death and defective myogenesis.
Soliman HAN, Toso EA, Darwish IE, Ali SM, Kyba M., Free PMC Article | 04/30/2022 |
| SNHG7 and FAIM2 are up-regulated and co-expressed in colorectal adenocarcinoma tissues.", trans "SNHG7 a FAIM2 jsou ve tkani kolorektalniho karcinomu up-regulovany a koexprimovany. | SNHG7 and FAIM2 are up-regulated and co-expressed in colorectal adenocarcinoma tissues.
Ziaee F, Hajjari M, Kazeminezhad RS, Behmanesh M. | 10/23/2021 |
| Analysis of Polymorphisms rs7093069-IL-2RA, rs7138803-FAIM2, and rs1748033-PADI4 in the Group of Adolescents With Autoimmune Thyroid Diseases. | Analysis of Polymorphisms rs7093069-IL-2RA, rs7138803-FAIM2, and rs1748033-PADI4 in the Group of Adolescents With Autoimmune Thyroid Diseases.
Sawicka B, Borysewicz-Sańczyk H, Wawrusiewicz-Kurylonek N, Aversa T, Corica D, Gościk J, Krętowski A, Waśniewska M, Bossowski A., Free PMC Article | 05/29/2021 |
| Interstitial serum albumin empowers osteosarcoma cells with FAIM2 transcription to obtain viability via dedifferentiation. | Interstitial serum albumin empowers osteosarcoma cells with FAIM2 transcription to obtain viability via dedifferentiation.
Pan Y, Zhang Y, Tang W, Zhang Y. | 12/5/2020 |
| Genome-wide investigation of DNA methylation in congenital adrenal hyperplasia. | Genome-wide investigation of DNA methylation in congenital adrenal hyperplasia.
Karlsson L, Barbaro M, Ewing E, Gomez-Cabrero D, Lajic S. | 11/21/2020 |
| Loci near TMEM18 (rs6548238), CDKAL1 (rs7754840), and FAIM2 (rs7138803) may be associated with obesity-related indicators, and loci near TMEM18 (rs6548238) and FAIM2 (rs7138803) may increase susceptibility of concurrent type 2 diabetes associated with obesity. | Obesity-related loci in TMEM18, CDKAL1 and FAIM2 are associated with obesity and type 2 diabetes in Chinese Han patients.
Kang J, Guan RC, Zhao Y, Chen Y., Free PMC Article | 05/9/2020 |
| DCST1-AS1 up-regulates the expression of FAIM2 by up-regulating the expression of miR-1254, ultimately promoting the proliferation of hepatocellular carcinoma cells. | LncRNA DCST1-AS1 functions as a competing endogenous RNA to regulate FAIM2 expression by sponging miR-1254 in hepatocellular carcinoma.
Chen J, Wu D, Zhang Y, Yang Y, Duan Y, An Y. | 11/23/2019 |
| Faim2 up-regulation may contribute to the neuroprotective effects of low-dose erythropoietin in transient brain ischemia | Faim2 contributes to neuroprotection by erythropoietin in transient brain ischemia.
Komnig D, Gertz K, Habib P, Nolte KW, Meyer T, Brockmann MA, Endres M, Rathkolb B, Hrabě de Angelis M, German Mouse Clinic Consortium, Schulz JB, Falkenburger BH, Reich A. | 05/11/2019 |
| results suggest that high level miR-3202 in T lymphocytes may protect epithelial cells through targeting FAIM2. MiR-3202 might be used as a notable biomarker of chronic obstructive pulmonary disease . | MiR-3202 protects smokers from chronic obstructive pulmonary disease through inhibiting FAIM2: An in vivo and in vitro study.
Shen W, Liu J, Fan M, Wang S, Zhang Y, Wen L, Wang R, Wei W, Li N, Zhang Y, Zhao G. | 10/6/2018 |
| that miR-193b is indispensible for the competitive endogenous RNA role of SNHG7 in FAIM2-supported tumourigenesis of lung cancer | miR-193b availability is antagonized by LncRNA-SNHG7 for FAIM2-induced tumour progression in non-small cell lung cancer.
She K, Yan H, Huang J, Zhou H, He J., Free PMC Article | 01/27/2018 |
| our research showed that lncRNA-SNHG7 promotes the proliferation, migration and invasion, and inhibits apoptosis of lung cancer cells by enhancing the FAIM2 expression, suggesting that lncRNA-SNHG7 as a key regulator of gene expression, may be a promising therapeutic strategy for the treatment of lung cancer | lncRNA-SNHG7 promotes the proliferation, migration and invasion and inhibits apoptosis of lung cancer cells by enhancing the FAIM2 expression.
She K, Huang J, Zhou H, Huang T, Chen G, He J. | 03/18/2017 |
| FAIM2 expression is significantly downregulated in human masticatory mucosa during wound healing | Human gingiva transcriptome during wound healing.
Wang Y, Tatakis DN. | 03/22/2017 |
| The interaction of TRIM21 and LFG was analyzed by co-immunoprecipitation. To examine changes in regulatory processes, western blot analyses, real-time PCR, activity of apoptotic process and flow cytometric analyses were carried out. | TRIM21, a negative modulator of LFG in breast carcinoma MDA-MB-231 cells in vitro.
Müller J, Maurer V, Reimers K, Vogt PM, Bucan V., Free PMC Article | 08/6/2016 |
| There are significant differences in the associations of the FAIM2 promoter methylation with sedentary behaviour and physical activity between obese and lean children. | Influence of lifestyle on the FAIM2 promoter methylation between obese and lean children: a cohort study.
Wu L, Zhao X, Shen Y, Huang G, Zhang M, Yan Y, Hou D, Meng L, Liu J, Cheng H, Mi J., Free PMC Article | 01/16/2016 |
| Methylation levels of the FAIM2 promoter are significantly associated with obesity and are independently associated with dyslipidaemia and its components in Chinese children. | Promoter methylation of fas apoptotic inhibitory molecule 2 gene is associated with obesity and dyslipidaemia in Chinese children.
Wu L, Zhao X, Shen Y, Zhang MX, Yan Y, Hou D, Meng L, Liu J, Cheng H, Mi J. | 01/16/2016 |
| Low KRT13 mRNA expression is associated with oral squamous cell carcinoma. | KRT13, FAIM2 and CYP2W1 mRNA expression in oral squamous cell carcinoma patients with risk habits.
Hartanto FK, Karen-Ng LP, Vincent-Chong VK, Ismail SM, Mustafa WM, Abraham MT, Tay KK, Zain RB. | 12/12/2015 |
| These results suggest that the TMBIM family has comparable functions in the maintenance of intracellular Ca(2) homeostasis in a wide variety of tissues | The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA²⁺-filling state.
Lisak DA, Schacht T, Enders V, Habicht J, Kiviluoto S, Schneider J, Henke N, Bultynck G, Methner A. | 10/3/2015 |
| Results indicated that FAIM2 beta-isoform is strongly expressed in breast tumour tissues. Fas sensitivity was reduced in the MCF10A breast cells expressing the FAIM2 beta-isoform. | Role of lifeguard β-isoform in the development of breast cancer.
Dastagir N, Lazaridis A, Dastagir K, Reimers K, Vogt PM, Bucan V., Free PMC Article | 06/6/2015 |
| This study highlighted the importance of two candidate genes, SH2B1 and FAIM2, in the risk of overweight/obesity. | Meta-analyses between 18 candidate genetic markers and overweight/obesity.
Tang L, Ye H, Hong Q, Chen F, Wang Q, Xu L, Bu S, Liu Q, Ye M, Wang DW, Mai Y, Duan S., Free PMC Article | 09/6/2014 |
| A polymorphism in FAIM2 is associated with higher myocardial infarction risk in type-2 diabetes mellitus subjects. | Novel association of the obesity risk-allele near Fas Apoptotic Inhibitory Molecule 2 (FAIM2) gene with heart rate and study of its effects on myocardial infarction in diabetic participants of the PREDIMED trial.
Corella D, Sorlí JV, González JI, Ortega C, Fitó M, Bulló M, Martínez-González MA, Ros E, Arós F, Lapetra J, Gómez-Gracia E, Serra-Majem L, Ruiz-Gutierrez V, Fiol M, Coltell O, Vinyoles E, Pintó X, Martí A, Saiz C, Ordovás JM, Estruch R., Free PMC Article | 08/30/2014 |
| The rs7138803 variant of FAIM2 was found to exert no effect on obesity in a Chinese Han population. | Common rs7138803 variant of FAIM2 and obesity in Han Chinese.
Li C, Qiu X, Yang N, Gao J, Rong Y, Xiong C, Zheng F., Free PMC Article | 04/26/2014 |
| Faim2 is physiologically expressed in brain in bacterial meningitis. | Modulation of hippocampal neuroplasticity by Fas/CD95 regulatory protein 2 (Faim2) in the course of bacterial meningitis.
Tauber SC, Harms K, Falkenburger B, Weis J, Sellhaus B, Nau R, Schulz JB, Reich A., Free PMC Article | 03/1/2014 |