| [High expression of Circ-PALLD in heart failure is transcriptionally regulated by the transcription factor GATA4]. | [High expression of Circ-PALLD in heart failure is transcriptionally regulated by the transcription factor GATA4].
Huang Z, Zeng Z, Li J, Cai R, He W, Hu S., Free PMC Article | 09/20/2023 |
| Palladin promotes cancer stem cell-like properties in lung cancer by activating Wnt/Beta-Catenin signaling. | Palladin promotes cancer stem cell-like properties in lung cancer by activating Wnt/Β-Catenin signaling.
Shu X, Chen M, Liu SY, Yu L, Sun LX, Sun LC, Ran YL., Free PMC Article | 03/2/2023 |
| Different Extracellular beta-Amyloid (1-42) Aggregates Differentially Impair Neural Cell Adhesion and Neurite Outgrowth through Differential Induction of Scaffold Palladin. | Different Extracellular β-Amyloid (1-42) Aggregates Differentially Impair Neural Cell Adhesion and Neurite Outgrowth through Differential Induction of Scaffold Palladin.
Zhang T, Song C, Li H, Zheng Y, Zhang Y., Free PMC Article | 01/21/2023 |
| PALLD mutation in a European family conveys a stromal predisposition for familial pancreatic cancer. | PALLD mutation in a European family conveys a stromal predisposition for familial pancreatic cancer.
Liotta L, Lange S, Maurer HC, Olive KP, Braren R, Pfarr N, Burger S, Muckenhuber A, Jesinghaus M, Steiger K, Weichert W, Friess H, Schmid R, Algül H, Jost PJ, Ramser J, Fischer C, Quante AS, Reichert M, Quante M., Free PMC Article | 12/11/2021 |
| Palladin isoforms 3 and 4 regulate cancer-associated fibroblast pro-tumor functions in pancreatic ductal adenocarcinoma. | Palladin isoforms 3 and 4 regulate cancer-associated fibroblast pro-tumor functions in pancreatic ductal adenocarcinoma.
Alexander JI, Vendramini-Costa DB, Francescone R, Luong T, Franco-Barraza J, Shah N, Gardiner JC, Nicolas E, Raghavan KS, Cukierman E., Free PMC Article | 12/4/2021 |
| Expression of palladin is associated with disease progression in metastatic high-grade serous carcinoma. | Expression of palladin is associated with disease progression in metastatic high-grade serous carcinoma.
Davidson B, Bock AJ, Holth A, Nymoen DA. | 08/14/2021 |
| Taken together, this study demonstrates that palladin plays an important role in themorphology and dynamic behavior of podocytes in vivo and in vitro. | The Role of Palladin in Podocytes.
Artelt N, Ludwig TA, Rogge H, Kavvadas P, Siegerist F, Blumenthal A, van den Brandt J, Otey CA, Bang ML, Amann K, Chadjichristos CE, Chatziantoniou C, Endlich K, Endlich N., Free PMC Article | 09/14/2019 |
| findings revealed that Palladin regulates spindle orientation and mitotic progression mainly through the AKT1-GSK3beta pathway. | Palladin is a novel microtubule-associated protein responsible for spindle orientation.
Zhang X, Chen X, Liu J, Xu X, Zhang Y, Ruan Z, Xie Y, Huang Q, Yin T, Chen Z, Chen S., Free PMC Article | 06/29/2019 |
| Collectively, our results demonstrate that palladin can functionally replace the Arp2/3 complex during bacterial actin-based cellular entry and intracellular motility of Listeria monocytogenes. | Palladin Compensates for the Arp2/3 Complex and Supports Actin Structures during Listeria Infections.
Dhanda AS, Vogl AW, Albraiki SE, Otey CA, Beck MR, Guttman JA., Free PMC Article | 01/12/2019 |
| Twist1 appears to require both palladin and collagen alpha1(VI) as downstream effectors for its prometastatic effects, which could be future therapeutic targets in cancer metastasis. | Twist1-induced activation of human fibroblasts promotes matrix stiffness by upregulating palladin and collagen α1(VI).
García-Palmero I, Torres S, Bartolomé RA, Peláez-García A, Larriba MJ, Lopez-Lucendo M, Peña C, Escudero-Paniagua B, Muñoz A, Casal JI. | 09/2/2017 |
| Palladin role in the vascular smooth muscle cell differentiation and gene expression | Redox-Sensitive Regulation of Myocardin-Related Transcription Factor (MRTF-A) Phosphorylation via Palladin in Vascular Smooth Muscle Cell Differentiation Marker Gene Expression.
Lee M, San Martín A, Valdivia A, Martin-Garrido A, Griendling KK., Free PMC Article | 09/3/2016 |
| stromal palladin expression is a surrogate indicator of the treatment effect after chemoradiation therapy. | Stromal Palladin Expression Is an Independent Prognostic Factor in Pancreatic Ductal Adenocarcinoma.
Sato D, Tsuchikawa T, Mitsuhashi T, Hatanaka Y, Marukawa K, Morooka A, Nakamura T, Shichinohe T, Matsuno Y, Hirano S., Free PMC Article | 09/3/2016 |
| Study identified the actin-associated protein palladin as a key node in signaling pathways that result in fibroblast activation in the increased tissue stiffness of a tumor microenvironment | Palladin mediates stiffness-induced fibroblast activation in the tumor microenvironment.
McLane JS, Ligon LA., Free PMC Article | 04/23/2016 |
| Palladin interacts with MT1-MMP to promote tumor cell invasion in breast carcinoma. | Actin-associated protein palladin promotes tumor cell invasion by linking extracellular matrix degradation to cell cytoskeleton.
von Nandelstadh P, Gucciardo E, Lohi J, Li R, Sugiyama N, Carpen O, Lehti K., Free PMC Article | 05/30/2015 |
| palladin functions as a dynamic scaffolding protein that promotes the assembly of dorsal stress fibers by recruiting VASP to these structures. | Palladin promotes assembly of non-contractile dorsal stress fibers through VASP recruitment.
Gateva G, Tojkander S, Koho S, Carpen O, Lappalainen P. | 12/20/2014 |
| Palladin seems to regulate podosome and invodopodia formation through Rho GTPases. [Review] | Palladin regulation of the actin structures needed for cancer invasion.
Najm P, El-Sibai M., Free PMC Article | 12/6/2014 |
| A model whereby palladin-activated fibroblasts facilitate stromal-dependent metastasis and outgrowth of tumorigenic epithelium. | Arousal of cancer-associated stroma: overexpression of palladin activates fibroblasts to promote tumor invasion.
Brentnall TA, Lai LA, Coleman J, Bronner MP, Pan S, Chen R., Free PMC Article | 06/9/2012 |
| results indicate that palladin phosphorylation by ERK has an anti-migratory function, possibly by modulating interactions with molecules that regulate cell migration | Role of palladin phosphorylation by extracellular signal-regulated kinase in cell migration.
Asano E, Maeda M, Hasegawa H, Ito S, Hyodo T, Yuan H, Takahashi M, Hamaguchi M, Senga T., Free PMC Article | 05/26/2012 |
| Observations support the belief that stromal palladin assessments have clinical relevance thus validating the use of these 3D cultures to study both progressive RCC-associated stroma and stroma-dependent mechanisms affecting tumorigenesis. | Elevated expression of stromal palladin predicts poor clinical outcome in renal cell carcinoma.
Gupta V, Bassi DE, Simons JD, Devarajan K, Al-Saleem T, Uzzo RG, Cukierman E., Free PMC Article | 12/3/2011 |
| Palladin may identify primary pancreatic endocrine neoplasms with a propensity to metastasize to the liver | Palladin is a marker of liver metastasis in primary pancreatic endocrine carcinomas.
Henderson-Jackson EB, Helm J, Strosberg J, Nasir NA, Yeatman TJ, Kvols LK, Coppola D, Nasir A. | 10/22/2011 |
| these results suggested that palladin played a specific role in modulating the subcellular localization of the cytoplasmic ILKAP and promoting the ILKAP-induced apoptosis. | Palladin is a novel binding partner of ILKAP in eukaryotic cells.
Zhou W, Cui S, Han S, Cheng B, Zheng Y, Zhang Y. | 10/15/2011 |
| The A-allele of PALLD rs7439293 was not associated with progressive carotid atherosclerosis | Polymorphism of the palladin gene and cardiovascular outcome in patients with atherosclerosis.
Hoke M, Schillinger M, Dick P, Exner M, Koppensteiner R, Minar E, Mlekusch W, Schlager O, Wagner O, Mannhalter C. | 06/25/2011 |
| upregulation of 85-90 kDa palladin isoform may play a role in the establishment of the tumor-associated fibroblasts phenotype, and thus in the formation of a desmoplastic tumor microenvironment | Isoform-specific upregulation of palladin in human and murine pancreas tumors.
Goicoechea SM, Bednarski B, Stack C, Cowan DW, Volmar K, Thorne L, Cukierman E, Rustgi AK, Brentnall T, Hwang RF, McCulloch CA, Yeh JJ, Bentrem DJ, Hochwald SN, Hingorani SR, Kim HJ, Otey CA., Free PMC Article | 06/18/2011 |
| Akt signaling regulates the stability of palladin | Akt2 regulates expression of the actin-bundling protein palladin.
Chin YR, Toker A., Free PMC Article | 01/8/2011 |
| Palladin is an integral component of adherens junctions and plays a role in the localization of E-cadherin to the junctions. The loss of palladin may be an integral part of EMT, an early step in the metastatic spread of colon carcinoma. | Palladin, an actin-associated protein, is required for adherens junction formation and intercellular adhesion in HCT116 colorectal cancer cells.
Tay PN, Tan P, Lan Y, Leung CH, Laban M, Tan TC, Ni H, Manikandan J, Rashid SB, Yan B, Yap CT, Lim LH, Lim YC, Hooi SC. | 01/1/2011 |