| Variants in FOXC1 and FOXC2 identified in patients with conotruncal heart defects. | Variants in FOXC1 and FOXC2 identified in patients with conotruncal heart defects.
Wei W, Li B, Li F, Sun K, Jiang X, Xu R. | 06/3/2024 |
| The role of transcription factor FOXA1/C2/M1/O3/P1/Q1 in breast cancer. | The role of transcription factor FOXA1/C2/M1/O3/P1/Q1 in breast cancer.
Yuan H, Liang Y, Hu S, Chen J, You J, Jiang J, Luo M, Zeng M., Free PMC Article | 04/17/2024 |
| Up-regulation of microRNA-183 reduces FOXO1 expression in gastric cancer patients with Helicobacter pylori infection. | Up-regulation of microRNA-183 reduces FOXO1 expression in gastric cancer patients with Helicobacter pylori infection.
Qi C, Liu L, Wang J, Jin Y. | 11/22/2023 |
| FOXC2-AS1/FOXC2 axis mediates matrix stiffness-induced trans-differentiation of hepatic stellate cells into fibrosis-promoting myofibroblasts. | FOXC2-AS1/FOXC2 axis mediates matrix stiffness-induced trans-differentiation of hepatic stellate cells into fibrosis-promoting myofibroblasts.
Sun L, Li Y, Wang H, Xiao X, Luo X, Yang R, Li J, Ma Y, Liu Q, Tu K, Shi Y., Free PMC Article | 09/19/2023 |
| Defects in vein valve PROX1/FOXC2 antithrombotic pathway in endothelial cells drive the hypercoagulable state induced by trauma and critical illness. | Defects in vein valve PROX1/FOXC2 antithrombotic pathway in endothelial cells drive the hypercoagulable state induced by trauma and critical illness.
Hoofnagle MH, Hess A, Nalugo M, Ghosh S, Hughes SW, Fuchs A, Welsh JD, Kahn ML, Bochicchio GV, Randolph GJ, Leonard JM, Turnbull IR., | 07/28/2023 |
| The FOXC2 Transcription Factor: A Master Regulator of Chemoresistance in Cancer. | The FOXC2 Transcription Factor: A Master Regulator of Chemoresistance in Cancer.
Hargadon KM, Strong EW., Free PMC Article | 02/9/2023 |
| Genetic landscape of FOXC2 mutations in lymphedema-distichiasis syndrome: Different mechanism of pathogenicity for mutations in different domains. | Genetic landscape of FOXC2 mutations in lymphedema-distichiasis syndrome: Different mechanism of pathogenicity for mutations in different domains.
Jiang L, Ren W, Xie C, Duan S, Dai C, Wei Y, Luo D, Wang T, Gong B, Liu X, Yang Z, Ye Z, Chen H, Shi Y. | 09/17/2022 |
| Forkhead box C2 is associated with insulin resistance in gestational diabetes mellitus. | Forkhead box C2 is associated with insulin resistance in gestational diabetes mellitus.
Yang J, Liu F, Li Y, Wu D, Zhang Z, Chen S, Deng M, Yang C, Yang J. | 06/11/2022 |
| Digenic Inheritance of a FOXC2 Mutation and Two PIEZO1 Mutations Underlies Congenital Lymphedema in a Multigeneration Family. | Digenic Inheritance of a FOXC2 Mutation and Two PIEZO1 Mutations Underlies Congenital Lymphedema in a Multigeneration Family.
Mustacich DJ, Lai LW, Bernas MJ, Jones JA, Myles RJ, Kuo PH, Williams WH, Witte CL, Erickson RP, Witte MH., Free PMC Article | 03/5/2022 |
| FOXC2-AS1 stabilizes FOXC2 mRNA via association with NSUN2 in gastric cancer cells. | FOXC2-AS1 stabilizes FOXC2 mRNA via association with NSUN2 in gastric cancer cells.
Yan J, Liu J, Huang Z, Huang W, Lv J. | 01/29/2022 |
| MicroRNA199a5p regulates FOXC2 to control human vascular smooth muscle cell phenotypic switch. | MicroRNA‑199a‑5p regulates FOXC2 to control human vascular smooth muscle cell phenotypic switch.
Cao Y, Cao Z, Wang W, Jie X, Li L., Free PMC Article | 12/4/2021 |
| The prognostic significance of FOXC2 gene expression in cancer: A comprehensive analysis of RNA-seq data from the cancer genome atlas. | The prognostic significance of FOXC2 gene expression in cancer: A comprehensive analysis of RNA-seq data from the cancer genome atlas.
Hargadon KM, Győrffy B, Strong EW. | 10/23/2021 |
| Super-Enhancer-Associated Transcription Factors Maintain Transcriptional Regulation in Mature Podocytes. | Super-Enhancer-Associated Transcription Factors Maintain Transcriptional Regulation in Mature Podocytes.
Yang J, Zhang D, Motojima M, Kume T, Hou Q, Pan Y, Duan A, Zhang M, Jiang S, Hou J, Shi J, Qin Z, Liu Z., Free PMC Article | 10/9/2021 |
| Circular RNA PVT1 promotes metastasis via regulating of miR-526b/FOXC2 signals in OS cells. | Circular RNA PVT1 promotes metastasis via regulating of miR-526b/FOXC2 signals in OS cells.
Yan M, Gao H, Lv Z, Liu Y, Zhao S, Gong W, Liu W., Free PMC Article | 09/11/2021 |
| Imbalance between Expression of FOXC2 and Its lncRNA in Lymphedema-Distichiasis Caused by Frameshift Mutations. | Imbalance between Expression of FOXC2 and Its lncRNA in Lymphedema-Distichiasis Caused by Frameshift Mutations.
Missaglia S, Tavian D, Michelini S, Maltese PE, Bonanomi A, Bertelli M., Free PMC Article | 08/28/2021 |
| Lymphedema distichiasis syndrome may be caused by FOXC2 promoter-enhancer dissociation and disruption of a topological associated domain. | Lymphedema distichiasis syndrome may be caused by FOXC2 promoter-enhancer dissociation and disruption of a topological associated domain.
Wallis M, Pope-Couston R, Mansour J, Amor DJ, Tang P, Stock-Myer S. | 07/3/2021 |
| MiR-1231 enhances docetaxel sensitivity to gallbladder carcinoma cells by downregulating FOXC2. | MiR-1231 enhances docetaxel sensitivity to gallbladder carcinoma cells by downregulating FOXC2.
Gong YQ, Ni JL, Fang Q, Li T. | 06/26/2021 |
| Long non-coding RNA GClnc1 knockdown suppresses progression of epithelial ovarian cancer by recruiting FOXC2 to disrupt the NOTCH1/NF-kappaB/Snail pathway. | Long non-coding RNA GClnc1 knockdown suppresses progression of epithelial ovarian cancer by recruiting FOXC2 to disrupt the NOTCH1/NF-κB/Snail pathway.
Wu D, Ke Y, Xiao R, Liu J, Li Q, Wang Y. | 06/19/2021 |
| The Effect of FOXC2-AS1 on White Adipocyte Browning and the Possible Regulatory Mechanism. | The Effect of FOXC2-AS1 on White Adipocyte Browning and the Possible Regulatory Mechanism.
Wang Y, Hua S, Cui X, Cao Y, Wen J, Chi X, Ji C, Pang L, You L., Free PMC Article | 05/22/2021 |
| LncRNA FOXC2-AS1 enhances FOXC2 mRNA stability to promote colorectal cancer progression via activation of Ca(2+)-FAK signal pathway. | LncRNA FOXC2-AS1 enhances FOXC2 mRNA stability to promote colorectal cancer progression via activation of Ca(2+)-FAK signal pathway.
Pan K, Xie Y., Free PMC Article | 04/17/2021 |
| FOXC2 Disease Mutations Identified in Lymphedema Distichiasis Patients Impair Transcriptional Activity and Cell Proliferation. | FOXC2 Disease Mutations Identified in Lymphedema Distichiasis Patients Impair Transcriptional Activity and Cell Proliferation.
Tavian D, Missaglia S, Michelini S, Maltese PE, Manara E, Mordente A, Bertelli M., Free PMC Article | 02/20/2021 |
| LncRNA FOXC2-AS1 regulated proliferation and apoptosis of vascular smooth muscle cell through targeting miR-1253/FOXF1 axis in atherosclerosis. | LncRNA FOXC2-AS1 regulated proliferation and apoptosis of vascular smooth muscle cell through targeting miR-1253/FOXF1 axis in atherosclerosis.
Wang YQ, Xu ZM, Wang XL, Zheng JK, Du Q, Yang JX, Zhang HC. | 02/13/2021 |
| Functional polymorphisms in FOXC2 gene and Epithelial ovarian Cancer susceptibility in Chinese population. | Functional polymorphisms in FOXC2 gene and Epithelial ovarian Cancer susceptibility in Chinese population.
Zhou Z, Ou X, Zou Q, Chu L, Quan X, Chen Y, Liu Y., Free PMC Article | 11/21/2020 |
| we have demonstrated that FOXC2 is strongly expressed in primary, metastatic and castration resistant prostate cancers, and is a strong predictor of outcome, of potential importance for prognostication and targeted therapy. | FOXC2 expression and epithelial-mesenchymal phenotypes are associated with castration resistance, metastasis and survival in prostate cancer.
Børretzen A, Gravdal K, Haukaas SA, Beisland C, Akslen LA, Halvorsen OJ., Free PMC Article | 07/25/2020 |
| The expression pattern of FOXC2 during podocyte differentiation seems to be affected by miR-548c-5p. | Evidence for miR-548c-5p regulation of FOXC2 transcription through a distal genomic target site in human podocytes.
Christofides A, Papagregoriou G, Dweep H, Makrides N, Gretz N, Felekkis K, Deltas C., Free PMC Article | 06/20/2020 |