| The GWAS SNP rs80207740 modulates erythrocyte traits via allele-specific binding of IKZF1 and targeting XPO7 gene. | The GWAS SNP rs80207740 modulates erythrocyte traits via allele-specific binding of IKZF1 and targeting XPO7 gene.
Hu X, Wang J, Yang K, Fan H, Wu J, Ren J, Han G, Li J, Xue Z, Liu X, Lv X. | 08/6/2024 |
| CRISPR-based screening identifies XPO7 as a positive regulator of senescence. | CRISPR-based screening identifies XPO7 as a positive regulator of senescence.
Li LZ, Yang K, Jing Y, Fan Y, Jiang X, Wang S, Liu GH, Qu J, Ma S, Zhang W., Free PMC Article | 08/2/2023 |
| Exportin XPO7 acts as an oncogenic factor in prostate cancer via upregulation of TCF3. | Exportin XPO7 acts as an oncogenic factor in prostate cancer via upregulation of TCF3.
Lin Y, Zhan M, Xu B. | 08/1/2023 |
| XPO7 is a tumor suppressor regulating p21(CIP1)-dependent senescence. | XPO7 is a tumor suppressor regulating p21(CIP1)-dependent senescence.
Innes AJ, Sun B, Wagner V, Brookes S, McHugh D, Pombo J, Porreca RM, Dharmalingam G, Vernia S, Zuber J, Vannier JB, García-Escudero R, Gil J., Free PMC Article | 09/11/2021 |
| This establishes Xpo7 as a broad-spectrum bidirectional transporter and paves the way for a much deeper analysis of exportin and importin function in the future. | Xpo7 is a broad-spectrum exportin and a nuclear import receptor.
Aksu M, Pleiner T, Karaca S, Kappert C, Dehne HJ, Seibel K, Urlaub H, Bohnsack MT, Görlich D., Free PMC Article | 05/25/2019 |
| Knockdown of exportins 4, 5, and 7 altered thyroid hormone receptor shuttling dynamics, and when exportins 5 and 7 were overexpressed, TR distribution shifted toward the cytosol. | Multiple exportins influence thyroid hormone receptor localization.
Subramanian KS, Dziedzic RC, Nelson HN, Stern ME, Roggero VR, Bondzi C, Allison LA., Free PMC Article | 03/26/2016 |
| Human oligodendrogliomas cells stably expressing mutant XPO7 showed altered cell proliferation. | Tumor-specific mutations in low-frequency genes affect their functional properties.
Erdem-Eraslan L, Heijsman D, de Wit M, Kremer A, Sacchetti A, van der Spek PJ, Sillevis Smitt PA, French PJ., Free PMC Article | 02/6/2016 |
| RAN nucleo-cytoplasmic transport and mitotic spindle assembly partners XPO7 and TPX2 have roles in serous epithelial ovarian cancer | RAN nucleo-cytoplasmic transport and mitotic spindle assembly partners XPO7 and TPX2 are new prognostic biomarkers in serous epithelial ovarian cancer.
Cáceres-Gorriti KY, Carmona E, Barrès V, Rahimi K, Létourneau IJ, Tonin PN, Provencher D, Mes-Masson AM., Free PMC Article | 01/16/2016 |
| Knockdown of XPO7 reduced the amount of nuclear p65 following TNF stimulation. XPO7 binding to p65 is NLS independent | KPNB1, XPO7 and IPO8 mediate the translocation ofNF-κB/p65 into the nucleus.
Liang P, Zhang H, Wang G, Li S, Cong S, Luo Y, Zhang B. | 06/28/2014 |
| These biochemical and functional data reveal RANBP16 and RANBP17 as novel regulators of E2A protein action, and demonstrate specific interaction of E12 with RANBP17. | Identification of RANBP16 and RANBP17 as novel interaction partners for the bHLH transcription factor E12.
Lee JH, Zhou S, Smas CM., Free PMC Article | 02/26/2011 |
| STRADalpha facilitates nuclear export of LKB1 by serving as an adaptor between LKB1 and exportins CRM1 and exportin7. | STRADalpha regulates LKB1 localization by blocking access to importin-alpha, and by association with Crm1 and exportin-7.
Dorfman J, Macara IG., Free PMC Article | 01/21/2010 |
| Exportin 7-dependent nuclear export signals differ fundamentally from the leucine-rich, CRM1-dependent ones | Exportin 7 defines a novel general nuclear export pathway.
Mingot JM, Bohnsack MT, Jäkle U, Görlich D., Free PMC Article | 01/21/2010 |