| Identification of Germline FOXE1 and Somatic MAPK Pathway Gene Alterations in Patients with Malignant Struma Ovarii, Cleft Palate and Thyroid Cancer. | Identification of Germline FOXE1 and Somatic MAPK Pathway Gene Alterations in Patients with Malignant Struma Ovarii, Cleft Palate and Thyroid Cancer.
Pires C, Saramago A, Moura MM, Li J, Donato S, Marques IJ, Belo H, Machado AC, Cabrera R, Grünewald TGP, Leite V, Cavaco BM., Free PMC Article | 03/8/2024 |
| FOXE1 Contributes to the Development of Psoriasis by Regulating WNT5A. | FOXE1 Contributes to the Development of Psoriasis by Regulating WNT5A.
Liu M, Zhang G, Wang Z, Liu X, He K, Luo R, Duan Q, Bai R, Wang Y, Du W, Zheng Y, Shao Y. | 11/27/2023 |
| The high expression of FOXE1 in colorectal cancer predicts a promising prognosis: a retrospective study. | The high expression of FOXE1 in colorectal cancer predicts a promising prognosis: a retrospective study.
Liu X, Chen L, Wen F, Zheng S, Ge W. | 11/2/2023 |
| Adipocyte signaling affects thyroid-specific gene expression via down-regulation of TTF-2/FOXE1. | Adipocyte signaling affects thyroid-specific gene expression via down-regulation of TTF-2/FOXE1.
Zamboni M, Strimpakos G, Poggiogalle E, Donini LM, Civitareale D. | 01/7/2023 |
| The Effect of LL37 Antimicrobial Peptide on FOXE1 and lncRNA PTCSC 2 Genes Expression in Colorectal Cancer (CRC) and Normal Cells. | The Effect of LL37 Antimicrobial Peptide on FOXE1 and lncRNA PTCSC 2 Genes Expression in Colorectal Cancer (CRC) and Normal Cells.
Al-Darraji MN, Jasim SA, Salah Aldeen ODA, Ghasemian A, Rasheed M., Free PMC Article | 11/5/2022 |
| Genetic predisposition of SNPs in miRNA-149 (rs2292832) and FOXE1 (rs3758249) in thyroid Cancer. | Genetic predisposition of SNPs in miRNA-149 (rs2292832) and FOXE1 (rs3758249) in thyroid Cancer.
Khan R, Shaheen H, Mansoor Q, Abbasi SA, Fatima S, Ammar A, Baig RM. | 03/5/2022 |
| YY1-induced up-regulation of FOXE1 is negatively regulated by miR-129-5p and contributes to the progression of papillary thyroid microcarcinoma. | YY1-induced up-regulation of FOXE1 is negatively regulated by miR-129-5p and contributes to the progression of papillary thyroid microcarcinoma.
Li S, Zhang Z, Peng H, Xiao X. | 11/27/2021 |
| FOXE1 regulates migration and invasion in thyroid cancer cells and targets ZEB1. | FOXE1 regulates migration and invasion in thyroid cancer cells and targets ZEB1.
Morillo-Bernal J, Fernández LP, Santisteban P., Free PMC Article | 07/31/2021 |
| FOXE1 represses cell proliferation and Warburg effect by inhibiting HK2 in colorectal cancer. | FOXE1 represses cell proliferation and Warburg effect by inhibiting HK2 in colorectal cancer.
Dai W, Meng X, Mo S, Xiang W, Xu Y, Zhang L, Wang R, Li Q, Cai G., Free PMC Article | 06/12/2021 |
| Network-Based Analysis Reveals Association of FOXE1 Gene Polymorphisms in Thyroid Cancer Patients; A Case-Control Study in Southeast of Iran. | Network-Based Analysis Reveals Association of FOXE1 Gene Polymorphisms in Thyroid Cancer Patients; A Case-Control Study in Southeast of Iran.
Mehrazin A, Safarpour H, Davoudi ST, Parsamanesh N, Saeedi F, Miri-Moghaddam E., Free PMC Article | 06/12/2021 |
| A systematic review and meta-analysis on protective role of forkhead box E1 (FOXE1) polymorphisms in susceptibility to non-syndromic cleft lip/palate. | A systematic review and meta-analysis on protective role of forkhead box E1 (FOXE1) polymorphisms in susceptibility to non-syndromic cleft lip/palate.
Imani MM, Safaei M, Lopez-Jornet P, Sadeghi M. | 09/12/2020 |
| the polymorphism of FOXE1 rs10217225 was correlated with an increased risk of cleft lip with or without cleft palate, and the polymorphism of FOXE1 rs4460498 was a protective factor for non-syndromic cleft lip (Meta-Analysis) | Association between forkhead box E1 polymorphisms and risk of non-syndromic cleft lip with or without cleft palate: A meta-analysis.
Xiao WL, Jia KN, Yu G, Zhao N. | 05/30/2020 |
| MiR-524-5p targeting on FOXE1 and ITGA3 prevents thyroid cancer progression through different pathways including cell cycling and autophagy. | MicroRNA-524-5p suppresses the progression of papillary thyroid carcinoma cells via targeting on FOXE1 and ITGA3 in cell autophagy and cycling pathways.
Liu H, Chen X, Lin T, Chen X, Yan J, Jiang S., Free PMC Article | 05/30/2020 |
| Results indicate that high expression of FOXE1 may function as a tumor suppressor in the early stage of papillary thyroid cancer (PTC) and restrain the proliferation, migration and invasion of PTC by negatively regulating PDGFA expression. Thus, FOXE1 could serve as a prognostic biomarker for PTC. | FOXE1 inhibits cell proliferation, migration and invasion of papillary thyroid cancer by regulating PDGFA.
Ding Z, Ke R, Zhang Y, Fan Y, Fan J. | 05/23/2020 |
| Gli2 promoted the proliferation, migration, and invasion of TPC-1 cells by activating Wnt/beta-catenin and FOXE1 is involved in this process. | FOXE1 supports the tumor promotion of Gli2 on papillary thyroid carcinoma by the Wnt/β-catenin pathway.
Ma J, Huang X, Li Z, Shen Y, Lai J, Su Q, Zhao J, Xu J. | 05/23/2020 |
| GRHL3 SNPs interact with FAM49A, FOXE1, NTN1, and VAX1 in the pathogenesis of non-syndromic oral clefts in the Brazilian population. | Exploring GRHL3 polymorphisms and SNP-SNP interactions in the risk of non-syndromic oral clefts in the Brazilian population.
Azevedo CMS, Machado RA, Martelli-Júnior H, Reis SRA, Persuhn DC, Coletta RD, Rangel ALCA. | 01/25/2020 |
| The meta-analysis revealed that common variations of FOXE1 (rs965513, rs944289 and rs1867277) were risk factors associated with increased DTC susceptibility. | Exploration of the association between FOXE1 gene polymorphism and differentiated thyroid cancer: a meta-analysis.
Chen YH, Zhang YQ., Free PMC Article | 03/2/2019 |
| We confirmed the association of FOXE1 gene and cleft lip with or without cleft palate by a family based study. For the first time, rs1867277 was significantly associated with cleft lip with or without cleft palate | Association of SNP rs1867277 in FOXE1 Gene and Cleft Lip with or without Cleft Palate in a Han Chinese Population.
Xie L, Deng Y, Yuan Y, Tan X, Liu L, Li N, Deng C, Liu H, Dai L. | 09/29/2018 |
| Mutations of TTF2 is associated with risk of Papillary Thyroid Cancer in Chinese. Patients with Multiplendular goiter and no metastasis are more likely to suffer PTC. G/A mutation of TTF2 had a high correlation with PTC in the overall population. | Replication and Meta-Analysis of Common Gene Mutations in TTF1 and TTF2 with Papillary Thyroid Cancer.
Gao Y, Chen F, Niu S, Lin S, Li S., Free PMC Article | 05/31/2018 |
| Report that PTCSC2 binds myosin-9 (MYH9). In a bidirectional promoter shared by FOXE1 and PTCSC2, MYH9 inhibits the promoter activity in both directions. This inhibition can be reversed by PTCSC2, which acts as a suppressor. | MYH9 binds to lncRNA gene PTCSC2 and regulates FOXE1 in the 9q22 thyroid cancer risk locus.
Wang Y, He H, Li W, Phay J, Shen R, Yu L, Hancioglu B, de la Chapelle A., Free PMC Article | 04/21/2018 |
| replication confirmed at genome-wide significance the association of loci at FOXE1 with hypothyroidism, and PDE8B, CAPZB and PDE10A with serum TSH. A total of 12 SNPs seemed to explain nearly 7% of the serum TSH variation | Replication confirms the association of loci in FOXE1, PDE8B, CAPZB and PDE10A with thyroid traits: a Genetics of Diabetes Audit and Research Tayside study (GoDARTS).
Soto-Pedre E, Siddiqui MK, Doney AS, Palmer CNA, Pearson ER, Leese GP. | 03/10/2018 |
| The functional variants rs965513 and rs1867277 independently contribute to genetic predisposition to papillary thyroid carcinoma, while a contributing role of the FOXE1 poly-Ala polymorphism could not be confirmed. | Genotype Analyses in the Japanese and Belarusian Populations Reveal Independent Effects of rs965513 and rs1867277 but Do Not Support the Role of FOXE1 Polyalanine Tract Length in Conferring Risk for Papillary Thyroid Carcinoma.
Nikitski AV, Rogounovitch TI, Bychkov A, Takahashi M, Yoshiura KI, Mitsutake N, Kawaguchi T, Matsuse M, Drozd VM, Demidchik Y, Nishihara E, Hirokawa M, Miyauchi A, Rubanovich AV, Matsuda F, Yamashita S, Saenko VA. | 03/3/2018 |
| FOXE1 interacts with ELK1 on thyroid relevant gene promoters, establishing a new regulatory pathway for its role in adult thyroid function. Co-regulation of TERT suggests a mechanism by which allelic variants in/near FOXE1 are associated with thyroid cancer risk. | Thyroid transcription factor FOXE1 interacts with ETS factor ELK1 to co-regulate TERT.
Bullock M, Lim G, Li C, Choi IH, Kochhar S, Liddle C, Zhang L, Clifton-Bligh RJ., Free PMC Article | 02/24/2018 |
| In a Cuban population, differentiated thyroid cancer risk was positively and strongly associated with the number of copies in the minor allele (A) for SNP rs965513 near FOXE1 among people who consumed less iodine than the median. | FOXE1 Polymorphism Interacts with Dietary Iodine Intake in Differentiated Thyroid Cancer Risk in the Cuban Population.
Ren Y, Lence-Anta JJ, Pereda CM, Chappe M, Velasco M, Infante I, Bustillo M, Turcios S, Leufroy A, Guérin T, Noël L, Lesueur F, Maillard S, Cléro E, Xhaard C, Allodji RS, Rubino C, Rodriguez R, Ortiz RM, de Vathaire F. | 02/17/2018 |
| methylation-mediated silencing of FOXE1 expression may contribute to the progression of CRC. | Aberrant Methylation of FOXE1 Contributes to a Poor Prognosis for Patients with Colorectal Cancer.
Sugimachi K, Matsumura T, Shimamura T, Hirata H, Uchi R, Ueda M, Sakimura S, Iguchi T, Eguchi H, Masuda T, Morita K, Takenaka K, Maehara Y, Mori M, Mimori K. | 01/20/2018 |