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    RFTN1 raftlin, lipid raft linker 1 [ Homo sapiens (human) ]

    Gene ID: 23180, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Association between raftlin and presepsin levels with periodontal healthy and disease conditions.

    Association between raftlin and presepsin levels with periodontal healthy and disease conditions.
    Özdemir EÇ, Uzunkaya M, Gündoğar H, Kurutaş EB.

    02/29/2024
    Raftlin and 8-iso-prostaglandin F2alpha levels and gene network analysis in patients with Modic changes.

    Raftlin and 8-iso-prostaglandin F2α levels and gene network analysis in patients with Modic changes.
    Demirhan İ, Oner E, Yuksel Z, Yuksel M, Belge Kurutas E.

    06/30/2023
    Serum NOX1 and Raftlin as new potential biomarkers of Major Depressive Disorder: A study in treatment-naive first episode patients.

    Serum NOX1 and Raftlin as new potential biomarkers of Major Depressive Disorder: A study in treatment-naive first episode patients.
    Hursitoglu O, Kurutas EB, Strawbridge R, Oner E, Gungor M, Tuman TC, Uygur OF.

    12/3/2022
    Expression of Major Lipid Raft Protein Raftlin in Chronic Rhinosinusitis with Nasal Polyps in Smoking and Non-Smoking Patients Correlated with Interleukin-17 and Tumor Necrosis Factor-alpha Levels.

    Expression of Major Lipid Raft Protein Raftlin in Chronic Rhinosinusitis with Nasal Polyps in Smoking and Non-Smoking Patients Correlated with Interleukin-17 and Tumor Necrosis Factor-α Levels.
    Lin YT, Tsai MH, Su YY, Chen WC, Huang SC, Chien CY., Free PMC Article

    10/8/2022
    RFTN1 facilitates gastric cancer progression by modulating AKT/p38 signaling pathways.

    RFTN1 facilitates gastric cancer progression by modulating AKT/p38 signaling pathways.
    Deng C, Zhang L, Ma X, Cai S, Jia Y, Zhao L.

    06/11/2022
    Raftlin is recruited by neuropilin-1 to the activated VEGFR2 complex to control proangiogenic signaling.

    Raftlin is recruited by neuropilin-1 to the activated VEGFR2 complex to control proangiogenic signaling.
    Bayliss AL, Sundararaman A, Granet C, Mellor H., Free PMC Article

    07/10/2021
    this study shows that raftlin appears to modulate cargo selection as an accessary protein of clathrin-associated adaptor protein-2 in clathrin-mediated endocytosis of TLR3/4 ligands

    Raftlin Controls Lipopolysaccharide-Induced TLR4 Internalization and TICAM-1 Signaling in a Cell Type-Specific Manner.
    Tatematsu M, Yoshida R, Morioka Y, Ishii N, Funami K, Watanabe A, Saeki K, Seya T, Matsumoto M.

    08/12/2017
    Mitogen-inducible Gene-2 expression is reduced in breast cancer.

    Mitogen-inducible Gene-2 (MIG2) and migfilin expression is reduced in samples of human breast cancer.
    Gkretsi V, Papanikolaou V, Zacharia LC, Athanassiou E, Wu C, Tsezou A.

    06/29/2013
    combination of ATOH7 and RFTN1 SNPs increased risk to POAG, indicating their diversified effects in the complex genetics of glaucoma.

    Interactive effects of ATOH7 and RFTN1 in association with adult-onset primary open-angle glaucoma.
    Chen JH, Wang D, Huang C, Zheng Y, Chen H, Pang CP, Zhang M.

    03/31/2012
    Raftlin cooperates with the uptake receptor to mediate cell entry of poly(I:C), which is critical for activation of TLR3.

    Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation.
    Watanabe A, Tatematsu M, Saeki K, Shibata S, Shime H, Yoshimura A, Obuse C, Seya T, Matsumoto M., Free PMC Article

    06/18/2011
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
    Observational study of gene-disease association. (HuGE Navigator)

    Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.
    Wheeler HE, Metter EJ, Tanaka T, Absher D, Higgins J, Zahn JM, Wilhelmy J, Davis RW, Singleton A, Myers RM, Ferrucci L, Kim SK., Free PMC Article

    12/2/2009
    These data suggest that Raftlin plays a pivotal role in the formation and/or maintenance of lipid rafts, therefore regulating B-cell antigen receptor-mediated signaling.

    The B cell-specific major raft protein, Raftlin, is necessary for the integrity of lipid raft and BCR signal transduction.
    Saeki K, Miura Y, Aki D, Kurosaki T, Yoshimura A., Free PMC Article

    01/21/2010
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