| Prevalence and clinical characteristics of T2DM patients with OTUD3 gene rs78466831 SNP at a single academic center in China. | Prevalence and clinical characteristics of T2DM patients with OTUD3 gene rs78466831 SNP at a single academic center in China.
Liu JP, Yang AP, Lei G, Yu M, Peng Y, Le AP., Free PMC Article | 12/24/2022 |
| Silencing of LncRNA SNHG6 protects trophoblast cells through regulating miR-101-3p/OTUD3 axis in unexplained recurrent spontaneous abortion. | Silencing of LncRNA SNHG6 protects trophoblast cells through regulating miR-101-3p/OTUD3 axis in unexplained recurrent spontaneous abortion.
Zhao L, Liu X, Ren C, Zhang H, Gao L. | 12/10/2022 |
| The deubiquitinase OTUD3 stabilizes ACTN4 to drive growth and metastasis of hepatocellular carcinoma. | The deubiquitinase OTUD3 stabilizes ACTN4 to drive growth and metastasis of hepatocellular carcinoma.
Xie P, Chen Y, Zhang H, Zhou G, Chao Q, Wang J, Liu Y, Fang J, Xie J, Zhen J, Wang Z, Hao L, Huang D., Free PMC Article | 01/15/2022 |
| Nicotine-mediated OTUD3 downregulation inhibits VEGF-C mRNA decay to promote lymphatic metastasis of human esophageal cancer. | Nicotine-mediated OTUD3 downregulation inhibits VEGF-C mRNA decay to promote lymphatic metastasis of human esophageal cancer.
Wang M, Li Y, Xiao Y, Yang M, Chen J, Jian Y, Chen X, Shi D, Chen X, Ouyang Y, Kong L, Huang X, Bai J, Lin C, Song L., Free PMC Article | 01/1/2022 |
| Ubiquitin ligase CHIP regulates OTUD3 stability and suppresses tumour metastasis in lung cancer. | Ubiquitin ligase CHIP regulates OTUD3 stability and suppresses tumour metastasis in lung cancer.
Zhang P, Li C, Li H, Yuan L, Dai H, Peng Z, Deng Z, Chang Z, Cui CP, Zhang L., Free PMC Article | 11/22/2021 |
| miR-520h Stimulates Drug Resistance to Paclitaxel by Targeting the OTUD3-PTEN Axis in Breast Cancer. | miR-520h Stimulates Drug Resistance to Paclitaxel by Targeting the OTUD3-PTEN Axis in Breast Cancer.
Geng W, Song H, Zhao Q, Dong K, Pu Q, Gao H, Lv Y., Free PMC Article | 04/24/2021 |
| Tumor suppressor OTUD3 induces growth inhibition and apoptosis by directly deubiquitinating and stabilizing p53 in invasive breast carcinoma cells. | Tumor suppressor OTUD3 induces growth inhibition and apoptosis by directly deubiquitinating and stabilizing p53 in invasive breast carcinoma cells.
Pu Q, Lv YR, Dong K, Geng WW, Gao HD., Free PMC Article | 02/27/2021 |
| MicroRNA 32 promotes cell proliferation, migration, and suppresses apoptosis in colon cancer cells by targeting OTU domain containing 3. | MicroRNA 32 promotes cell proliferation, migration, and suppresses apoptosis in colon cancer cells by targeting OTU domain containing 3.
Jin Y, Cheng H, Cao J, Shen W. | 10/3/2020 |
| Acetylation-Dependent Deubiquitinase OTUD3 Controls MAVS Activation in Innate Antiviral Immunity. | Acetylation-Dependent Deubiquitinase OTUD3 Controls MAVS Activation in Innate Antiviral Immunity.
Zhang Z, Fang X, Wu X, Ling L, Chu F, Li J, Wang S, Zang J, Zhang B, Ye S, Zhang L, Yang B, Lin S, Huang H, Wang A, Zhou F. | 09/5/2020 |
| Knockdown of OTUD3 results in a decrease in the level of GRP78 protein, suppression of cell growth and migration, and tumorigenesis in lung cancer. | The deubiquitylase OTUD3 stabilizes GRP78 and promotes lung tumorigenesis.
Du T, Li H, Fan Y, Yuan L, Guo X, Zhu Q, Yao Y, Li X, Liu C, Yu X, Liu Z, Cui CP, Han C, Zhang L., Free PMC Article | 09/14/2019 |
| OTUD3 is an essential regulator of PTEN and the OTUD3-PTEN signalling axis plays a critical role in tumour suppression. | Deubiquitylase OTUD3 regulates PTEN stability and suppresses tumorigenesis.
Yuan L, Lv Y, Li H, Gao H, Song S, Zhang Y, Xing G, Kong X, Wang L, Li Y, Zhou T, Gao D, Xiao ZX, Yin Y, Wei W, He F, Zhang L. | 04/30/2016 |
| Single-nucleotide polymorphism in OTUD3 gene is associated with ulcerative colitis. | Genome-wide association study of ulcerative colitis in Koreans suggests extensive overlapping of genetic susceptibility with Caucasians.
Yang SK, Hong M, Zhao W, Jung Y, Tayebi N, Ye BD, Kim KJ, Park SH, Lee I, Shin HD, Cheong HS, Kim LH, Kim HJ, Jung SA, Kang D, Youn HS, Liu J, Song K. | 09/28/2013 |