| KIF13B mediates VEGFR2 recycling to modulate vascular permeability. | KIF13B mediates VEGFR2 recycling to modulate vascular permeability.
Cho HD, Nhàn NTT, Zhou C, Tu K, Nguyen T, Sarich NA, Yamada KH., Free PMC Article | 04/5/2023 |
| Transient accumulation and bidirectional movement of KIF13B in primary cilia. | Transient accumulation and bidirectional movement of KIF13B in primary cilia.
Juhl AD, Anvarian Z, Kuhns S, Berges J, Andersen JS, Wüstner D, Pedersen LB. | 05/28/2022 |
| Changes in Protein Glycosylation as a Result of Aptamer Interactions with Cancer Cells. | Changes in Protein Glycosylation as a Result of Aptamer Interactions with Cancer Cells.
Drabik A, Ner-Kluza J, Hartman K, Mayer G, Silberring J. | 11/21/2020 |
| Study provides evidence that KIF13B and NPHP4 are both required for establishment of a specialized caveolin-1 membrane microdomain at the ciliary transition zone, which is essential for Shh-induced accumulation of SMO in the primary cilium as well as for activation of GLI-mediated target gene expression. | KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling.
Schou KB, Mogensen JB, Morthorst SK, Nielsen BS, Aleliunaite A, Serra-Marques A, Fürstenberg N, Saunier S, Bizet AA, Veland IR, Akhmanova A, Christensen ST, Pedersen LB., Free PMC Article | 11/24/2018 |
| Findings show that the high-affinity binding of KIF13B to DLG guanylate kinase (GK) domain does not require phosphorylation of KIF13B and that DLG binds to an unphosphorylated and autonomously folded domain within its stalk region (MAGUK binding stalk [MBS] domain) with high specificity and affinity. | An Atypical MAGUK GK Target Recognition Mode Revealed by the Interaction between DLG and KIF13B.
Zhu J, Shang Y, Xia Y, Zhang R, Zhang M. | 07/15/2017 |
| lnc-KIF13B-1, a long non-coding RNA (rs6434720) is associated with corticobasal degeneration. | Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy.
Kouri N, Ross OA, Dombroski B, Younkin CS, Serie DJ, Soto-Ortolaza A, Baker M, Finch NCA, Yoon H, Kim J, Fujioka S, McLean CA, Ghetti B, Spina S, Cantwell LB, Farlow MR, Grafman J, Huey ED, Ryung Han M, Beecher S, Geller ET, Kretzschmar HA, Roeber S, Gearing M, Juncos JL, Vonsattel JPG, Van Deerlin VM, Grossman M, Hurtig HI, Gross RG, Arnold SE, Trojanowski JQ, Lee VM, Wenning GK, White CL, Höglinger GU, Müller U, Devlin B, Golbe LI, Crook J, Parisi JE, Boeve BF, Josephs KA, Wszolek ZK, Uitti RJ, Graff-Radford NR, Litvan I, Younkin SG, Wang LS, Ertekin-Taner N, Rademakers R, Hakonarsen H, Schellenberg GD, Dickson DW., Free PMC Article | 04/9/2016 |
| KIF13B is an essential molecular motor required for the trafficking of VEGFR2 from the Golgi, and its delivery to the endothelial cell surface mediates angiogenesis. | KIF13B regulates angiogenesis through Golgi to plasma membrane trafficking of VEGFR2.
Yamada KH, Nakajima Y, Geyer M, Wary KK, Ushio-Fukai M, Komarova Y, Malik AB., Free PMC Article | 11/14/2015 |
| Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin alpha1. | Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin alpha1.
Tong Y, Tempel W, Wang H, Yamada K, Shen L, Senisterra GA, MacKenzie F, Chishti AH, Park HW., Free PMC Article | 01/22/2011 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| These results reveal that GAKIN/KIF13B is a key intermediate linking Par1b to the regulation of axon formation. | Par1b/MARK2 phosphorylates kinesin-like motor protein GAKIN/KIF13B to regulate axon formation.
Yoshimura Y, Terabayashi T, Miki H., Free PMC Article | 05/3/2010 |
| Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | Human variation in alcohol response is influenced by variation in neuronal signaling genes.
Joslyn G, Ravindranathan A, Brush G, Schuckit M, White RL. | 04/7/2010 |
| Binding of the SH3-I3-GUK module of hDlg to GAKIN activates the microtubule-stimulated ATPase activity of GAKIN by approximately 10-fold. We propose: the cargo-mediated regulation of motor activity is a general paradigm for the activation of kinesins. | The effector domain of human Dlg tumor suppressor acts as a switch that relieves autoinhibition of kinesin-3 motor GAKIN/KIF13B.
Yamada KH, Hanada T, Chishti AH., Free PMC Article | 01/21/2010 |
| These results suggest that, in neurons, the GAKIN-PIP3BP complex transports PIP3 to the neurite ends and regulates neuronal polarity formation. | Transport of PIP3 by GAKIN, a kinesin-3 family protein, regulates neuronal cell polarity.
Horiguchi K, Hanada T, Fukui Y, Chishti AH., Free PMC Article | 01/21/2010 |