Hsa_circ_0001361 facilitates cell progression and glycolytic metabolism in neuroblastoma via interacting with mir-490-5p to induce TRIM2 upregulation. | Hsa_circ_0001361 facilitates cell progression and glycolytic metabolism in neuroblastoma via interacting with mir-490-5p to induce TRIM2 upregulation. Lv R, Lu F, Xu S. | 05/30/2023 |
Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity. | Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity. Esposito D, Dudley-Fraser J, Garza-Garcia A, Rittinger K., Free PMC Article | 12/24/2022 |
Expression and Role of TRIM2 in Human Diseases. | Expression and Role of TRIM2 in Human Diseases. Xiao M, Li J, Liu Q, He X, Yang Z, Wang D., Free PMC Article | 09/10/2022 |
Knockdown of long noncoding RNA DLEU2 suppresses idiopathic pulmonary fibrosis by regulating the microRNA3693p/TRIM2 axis. | Knockdown of long non‑coding RNA DLEU2 suppresses idiopathic pulmonary fibrosis by regulating the microRNA‑369‑3p/TRIM2 axis. Yi H, Luo D, Xiao Y, Jiang D., Free PMC Article | 11/13/2021 |
Long non-coding RNA NR2F1-AS1 promoted neuroblastoma progression through miR-493-5p/TRIM2 axis. | Long non-coding RNA NR2F1-AS1 promoted neuroblastoma progression through miR-493-5p/TRIM2 axis. Liu L, Zhao H, He HH, Huang J, Xu YY, Li XL, Wu Y, Wang J, Zhu YB. | 07/3/2021 |
Oncogenic function of TRIM2 in pancreatic cancer by activating ROS-related NRF2/ITGB7/FAK axis. | Oncogenic function of TRIM2 in pancreatic cancer by activating ROS-related NRF2/ITGB7/FAK axis. Sun Q, Ye Z, Qin Y, Fan G, Ji S, Zhuo Q, Xu W, Liu W, Hu Q, Liu M, Zhang Z, Xu X, Yu X. | 12/19/2020 |
TRIM2 expression was significantly higher in colorectal cancer tissues than in non-cancerous tissues and was significantly associated with some clinicopathological factors. The results indicate that TRIM2 is a novel promoter of human colorectal cancer. | TRIM2 is a novel promoter of human colorectal cancer. Cao H, Fang Y, Liang Q, Wang J, Luo B, Zeng G, Zhang T, Jing X, Wang X. | 03/14/2020 |
TRIM2, a novel member of the antiviral family, limits New World arenavirus entry. | TRIM2, a novel member of the antiviral family, limits New World arenavirus entry. Sarute N, Ibrahim N, Medegan Fagla B, Lavanya M, Cuevas C, Stavrou S, Otkiran-Clare G, Tyynismaa H, Henao-Mejia J, Ross SR., Free PMC Article | 11/30/2019 |
Study revealed that TRIM2 performs important functions in regulating the development and metastasis of osteosarcoma. | TRIM2 regulates the development and metastasis of tumorous cells of osteosarcoma. Qin Y, Ye J, Zhao F, Hu S, Wang S. | 12/22/2018 |
TRIM2 is associated with clinical fibrotic phenotypes of eosinophilic esophagitis. | Gene expression-phenotype associations in adults with eosinophilic esophagitis. Dellon ES, Selitsky SR, Genta RM, Lash RH, Parker JS., Free PMC Article | 11/17/2018 |
We found that CREBRF and TRIM2 mRNA were significantly upregulated by rHDL, particularly in response to its phospholipid component 1-palmitoyl-2-linoleoyl-phosphatidylcholine, however, protein expression was not significantly altered. | Exploring the Roles of CREBRF and TRIM2 in the Regulation of Angiogenesis by High-Density Lipoproteins. Wong NKP, Cheung H, Solly EL, Vanags LZ, Ritchie W, Nicholls SJ, Ng MKC, Bursill CA, Tan JTM., Free PMC Article | 10/27/2018 |
Studies indicate most-studied TRIpartite Motif (TRIM)-NHL proteins TRIM2, TRIM3, TRIM32 and TRIM71, and their mutations have been linked to diseases. | TRIM-NHL proteins in development and disease. Tocchini C, Ciosk R. | 10/1/2016 |
TRIM2 homozygous missense mutation (c.2000A>C; p.D667A) in a patient with peripheral neuropathy and bilateral vocal cord paralysis | Exome sequencing reveals homozygous TRIM2 mutation in a patient with early onset CMT and bilateral vocal cord paralysis. Pehlivan D, Coban Akdemir Z, Karaca E, Bayram Y, Jhangiani S, Yildiz EP, Muzny D, Uluc K, Gibbs RA, Baylor-Hopkins Center for Mendelian Genomics, Elcioglu N, Lupski JR, Harel T., Free PMC Article | 07/25/2015 |
The functional role of the C-terminal NHL domain was characterized in TRIM2. | Expression, purification, crystallization and preliminary X-ray diffraction analysis of the C-terminal NHL domain of human TRIM2. Guan X, Li J, Lü X, Dong Y, Chen W, Li X., Free PMC Article | 01/31/2015 |
TRIM2 is repressed by miR-9 and -181c, either alone or in combination. | Target gene repression mediated by miRNAs miR-181c and miR-9 both of which are down-regulated by amyloid-β. Schonrock N, Humphreys DT, Preiss T, Götz J. | 09/15/2012 |
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |