Ubiquitin-Specific Protease 22 Plays a Key Role in Increasing Extracellular Vesicle Secretion and Regulating Cell Motility of Lung Adenocarcinoma. | Ubiquitin-Specific Protease 22 Plays a Key Role in Increasing Extracellular Vesicle Secretion and Regulating Cell Motility of Lung Adenocarcinoma. Zhen F, Sun Y, Wang H, Liu W, Liang X, Wang Y, Wang Q, Hu J., Free PMC Article | 10/22/2024 |
USP22 is required for human endometrial stromal cell proliferation and decidualization by deubiquitinating FoxM1. | USP22 is required for human endometrial stromal cell proliferation and decidualization by deubiquitinating FoxM1. Zhou M, Gao Y, Wu S, Wang Y, Yang J. | 09/4/2024 |
USP22 as a key regulator of glycolysis pathway in osteosarcoma: insights from bioinformatics and experimental approaches. | USP22 as a key regulator of glycolysis pathway in osteosarcoma: insights from bioinformatics and experimental approaches. Zhang Q, Zhu J, Xie J, Gu Y, Chen L., Free PMC Article | 06/7/2024 |
USP22 supports the aggressive behavior of basal-like breast cancer by stimulating cellular respiration. | USP22 supports the aggressive behavior of basal-like breast cancer by stimulating cellular respiration. Prokakis E, Bamahmoud H, Jansari S, Fritsche L, Dietz A, Boshnakovska A, Rehling P, Johnsen SA, Gallwas J, Wegwitz F., Free PMC Article | 02/20/2024 |
ADAM9 deubiquitination induced by USP22 suppresses proliferation, migration, invasion, and epithelial-mesenchymal transition of trophoblast cells in preeclampsia. | ADAM9 deubiquitination induced by USP22 suppresses proliferation, migration, invasion, and epithelial-mesenchymal transition of trophoblast cells in preeclampsia. Liu J, Wang Y, Zhang S, Sun L, Shi Y. | 02/6/2024 |
USP22-JMJD8 axis promotes Lenvatinib resistance in hepatocellular carcinoma. | USP22-JMJD8 axis promotes Lenvatinib resistance in hepatocellular carcinoma. Guo J, Zhao J. | 11/29/2023 |
USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma. | USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma. Zeng K, Xie W, Wang C, Wang S, Liu W, Su Y, Lin L, Zou R, Sun G, Zhou B, Wang M, Luan R, Bai Y, Huo Y, Kato S, Zhong X, Zhao Y., Free PMC Article | 03/16/2023 |
Transcription factor AP2 enhances malignancy of non-small cell lung cancer through upregulation of USP22 gene expression. | Transcription factor AP2 enhances malignancy of non-small cell lung cancer through upregulation of USP22 gene expression. Sun T, Zhang K, Li W, Liu Y, Pangeni RP, Li A, Arvanitis L, Raz DJ., Free PMC Article | 10/1/2022 |
Immune Evasion and Drug Resistance Mediated by USP22 in Cancer: Novel Targets and Mechanisms. | Immune Evasion and Drug Resistance Mediated by USP22 in Cancer: Novel Targets and Mechanisms. Guo J, Zhao J, Fu W, Xu Q, Huang D., Free PMC Article | 08/13/2022 |
USP22 controls type III interferon signaling and SARS-CoV-2 infection through activation of STING. | USP22 controls type III interferon signaling and SARS-CoV-2 infection through activation of STING. Karlowitz R, Stanifer ML, Roedig J, Andrieux G, Bojkova D, Bechtel M, Smith S, Kowald L, Schubert R, Boerries M, Cinatl J Jr, Boulant S, van Wijk SJL., Free PMC Article | 08/13/2022 |
USP22 regulates lipidome accumulation by stabilizing PPARgamma in hepatocellular carcinoma. | USP22 regulates lipidome accumulation by stabilizing PPARγ in hepatocellular carcinoma. Ning Z, Guo X, Liu X, Lu C, Wang A, Wang X, Wang W, Chen H, Qin W, Liu X, Zhou L, Ma C, Du J, Lin Z, Luo H, Otkur W, Qi H, Chen D, Xia T, Liu J, Tan G, Xu G, Piao HL., Free PMC Article | 05/7/2022 |
Upregulation of USP22 and ABCC1 during Sorafenib Treatment of Hepatocellular Carcinoma Contribute to Development of Resistance. | Upregulation of USP22 and ABCC1 during Sorafenib Treatment of Hepatocellular Carcinoma Contribute to Development of Resistance. Chang YS, Su CW, Chen SC, Chen YY, Liang YJ, Wu JC., Free PMC Article | 04/16/2022 |
USP22-mediated deubiquitination of PTEN inhibits pancreatic cancer progression by inducing p21 expression. | USP22-mediated deubiquitination of PTEN inhibits pancreatic cancer progression by inducing p21 expression. Ren D, Sun Y, Li D, Wu H, Jin X., Free PMC Article | 04/16/2022 |
Long noncoding RNA CTBP1AS2 upregulates USP22 to promote pancreatic carcinoma progression by sponging miR1413p. | Long non‑coding RNA CTBP1‑AS2 upregulates USP22 to promote pancreatic carcinoma progression by sponging miR‑141‑3p. Zhang M, Ma S, Li X, Yu H, Tan Y, He J, Wei X, Ma J., Free PMC Article | 04/2/2022 |
USP22 deficiency in melanoma mediates resistance to T cells through IFNgamma-JAK1-STAT1 signal axis. | USP22 deficiency in melanoma mediates resistance to T cells through IFNγ-JAK1-STAT1 signal axis. Li M, Xu Y, Liang J, Lin H, Qi X, Li F, Han P, Gao Y, Yang X., Free PMC Article | 04/2/2022 |
Ring finger 220 promotes the stemness and progression of colon cancer cells via Ubiquitin specific peptidase 22-BMI1 axis. | Ring finger 220 promotes the stemness and progression of colon cancer cells via Ubiquitin specific peptidase 22-BMI1 axis. Yan J, Tan M, Yu L, Jin X, Li Y., Free PMC Article | 02/19/2022 |
USP22 regulates the formation and function of placental vasculature during the development of fetal growth restriction. | USP22 regulates the formation and function of placental vasculature during the development of fetal growth restriction. Liu Z, Wang J, Gao Y, Guo Y, Zhu Y, Sun Y, Yang H. | 02/5/2022 |
Ubiquitin-specific protease 22 ameliorates chronic alcohol-associated liver disease by regulating BRD4. | Ubiquitin-specific protease 22 ameliorates chronic alcohol-associated liver disease by regulating BRD4. Yan R, Chu J, Zhou Y, Shan W, Hu Y, Lin M, Zhao Y, Sun R, Wang Z, Lv L, Wang L, Yao J, Zhang N. | 01/22/2022 |
USP22 promotes HER2-driven mammary carcinoma aggressiveness by suppressing the unfolded protein response. | USP22 promotes HER2-driven mammary carcinoma aggressiveness by suppressing the unfolded protein response. Prokakis E, Dyas A, Grün R, Fritzsche S, Bedi U, Kazerouni ZB, Kosinsky RL, Johnsen SA, Wegwitz F., Free PMC Article | 01/15/2022 |
Targeting USP22 with miR305p to inhibit the hypoxiainduced expression of PDL1 in lung adenocarcinoma cells. | Targeting USP22 with miR‑30‑5p to inhibit the hypoxia‑induced expression of PD‑L1 in lung adenocarcinoma cells. Hua X, Chu H, Wang C, Shi X, Wang A, Zhang Z. | 01/8/2022 |
Deubiquitination of the repressor E2F6 by USP22 facilitates AKT activation and tumor growth in hepatocellular carcinoma. | Deubiquitination of the repressor E2F6 by USP22 facilitates AKT activation and tumor growth in hepatocellular carcinoma. Jing T, Wang B, Yang Z, Liu Y, Xu G, Xu X, Jiao K, Chen Z, Xiang L, Zhang L, Liu Y. | 01/8/2022 |
[Role of ubiquitin-specific peptidase 22 in multidrug resistance of colorectal cancer and its correlation with multidrug resistance gene P-gp]. | [Role of ubiquitin-specific peptidase 22 in multidrug resistance of colorectal cancer and its correlation with multidrug resistance gene P-gp]. Zhang L, Wang JY, Li X, Chen XY, Wu WX. | 01/1/2022 |
microRNA-362-3p targets USP22 to retard retinoblastoma growth via reducing deubiquitination of LSD1. | microRNA-362-3p targets USP22 to retard retinoblastoma growth via reducing deubiquitination of LSD1. Rong J, Li Z, Xu L, Lang L, Zheng G., Free PMC Article | 12/4/2021 |
USP22 positively modulates ERalpha action via its deubiquitinase activity in breast cancer. | USP22 positively modulates ERα action via its deubiquitinase activity in breast cancer. Wang S, Zhong X, Wang C, Luo H, Lin L, Sun H, Sun G, Zeng K, Zou R, Liu W, Sun N, Song H, Liu W, Zhang Q, Liao Z, Teng X, Zhou T, Sun X, Zhao Y., Free PMC Article | 11/22/2021 |
The SAGA complex regulates early steps in transcription via its deubiquitylase module subunit USP22. | The SAGA complex regulates early steps in transcription via its deubiquitylase module subunit USP22. Stanek TJ, Gennaro VJ, Tracewell MA, Di Marcantonio D, Pauley KL, Butt S, McNair C, Wang F, Kossenkov AV, Knudsen KE, Butt T, Sykes SM, McMahon SB., Free PMC Article | 11/22/2021 |