| SIRT5 promote malignant advancement of chordoma by regulating the desuccinylation of c-myc. | SIRT5 promote malignant advancement of chordoma by regulating the desuccinylation of c-myc.
Jiang M, Huang Z, Chen L, Deng T, Liu J, Wu Y., Free PMC Article | 03/29/2024 |
| SIRT5 rs12216101 T>G variant is associated with liver damage and mitochondrial dysfunction in patients with non-alcoholic fatty liver disease. | SIRT5 rs12216101 T>G variant is associated with liver damage and mitochondrial dysfunction in patients with non-alcoholic fatty liver disease.
Salomone F, Pipitone RM, Longo M, Malvestiti F, Amorini AM, Distefano A, Casirati E, Ciociola E, Iraci N, Leggio L, Zito R, Vicario N, Saoca C, Pennisi G, Cabibi D, Lazzarino G, Fracanzani AL, Dongiovanni P, Valenti L, Petta S, Volti GL, Grimaudo S. | 01/8/2024 |
| LDHA Desuccinylase Sirtuin 5 as A Novel Cancer Metastatic Stimulator in Aggressive Prostate Cancer. | LDHA Desuccinylase Sirtuin 5 as A Novel Cancer Metastatic Stimulator in Aggressive Prostate Cancer.
Kwon OK, Bang IH, Choi SY, Jeon JM, Na AY, Gao Y, Cho SS, Ki SH, Choe Y, Lee JN, Ha YS, Bae EJ, Kwon TG, Park BH, Lee S., Free PMC Article | 07/27/2023 |
| Role of SIRT5 in cancer. Friend or Foe? | Role of SIRT5 in cancer. Friend or Foe?
Lagunas-Rangel FA. | 06/1/2023 |
| The deacylase sirtuin 5 reduces malonylation in nonmitochondrial metabolic pathways in diabetic kidney disease. | The deacylase sirtuin 5 reduces malonylation in nonmitochondrial metabolic pathways in diabetic kidney disease.
Baek J, Sas K, He C, Nair V, Giblin W, Inoki A, Zhang H, Yingbao Y, Hodgin J, Nelson RG, Brosius FC 3rd, Kretzler M, Stemmer PM, Lombard DB, Pennathur S., Free PMC Article | 04/6/2023 |
| Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection. | Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection.
Fabbrizi E, Fiorentino F, Carafa V, Altucci L, Mai A, Rotili D., Free PMC Article | 04/5/2023 |
| Circ-ATL1 silencing reverses the activation effects of SIRT5 on smooth muscle cellular proliferation, migration and contractility in intracranial aneurysm by adsorbing miR-455. | Circ-ATL1 silencing reverses the activation effects of SIRT5 on smooth muscle cellular proliferation, migration and contractility in intracranial aneurysm by adsorbing miR-455.
Xu J, Fang C., Free PMC Article | 02/4/2023 |
| SIRT5 reduces the inflammatory response and barrier dysfunction in IL-17A-induced epidermal keratinocytes. | SIRT5 reduces the inflammatory response and barrier dysfunction in IL-17A-induced epidermal keratinocytes.
Wang C, He D, Shi C. | 01/14/2023 |
| Sirtuin5 protects colorectal cancer from DNA damage by keeping nucleotide availability. | Sirtuin5 protects colorectal cancer from DNA damage by keeping nucleotide availability.
Wang HL, Chen Y, Wang YQ, Tao EW, Tan J, Liu QQ, Li CM, Tong XM, Gao QY, Hong J, Chen YX, Fang JY., Free PMC Article | 10/22/2022 |
| SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein. | SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein.
Walter M, Chen IP, Vallejo-Gracia A, Kim IJ, Bielska O, Lam VL, Hayashi JM, Cruz A, Shah S, Soveg FW, Gross JD, Krogan NJ, Jerome KR, Schilling B, Ott M, Verdin E., Free PMC Article | 10/8/2022 |
| Knockdown of circLRWD1 weakens DDP resistance via reduction of SIRT5 expression through releasing miR-507 in non-small cell lung cancer. | Knockdown of circLRWD1 weakens DDP resistance via reduction of SIRT5 expression through releasing miR-507 in non-small cell lung cancer.
Deng Z, Tu Q, Hu G, Xing M. | 10/8/2022 |
| Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis. | Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis.
Sun R, Zhang Z, Bao R, Guo X, Gu Y, Yang W, Wei J, Chen X, Tong L, Meng J, Zhong C, Zhang C, Zhang J, Sun Y, Ling C, Tong X, Yu FX, Yu H, Qu W, Zhao B, Guo W, Qian M, Saiyin H, Liu Y, Liu RH, Xie C, Liu W, Xiong Y, Guan KL, Shi Y, Wang P, Ye D. | 07/23/2022 |
| SIRT5 is involved in the proliferation and metastasis of breast cancer by promoting aerobic glycolysis. | SIRT5 is involved in the proliferation and metastasis of breast cancer by promoting aerobic glycolysis.
He S, Jia Q, Zhou L, Wang Z, Li M. | 06/25/2022 |
| LINC01234 regulates microRNA-27b-5p to induce the migration, invasion and self-renewal of ovarian cancer stem cells through targeting SIRT5. | LINC01234 regulates microRNA-27b-5p to induce the migration, invasion and self-renewal of ovarian cancer stem cells through targeting SIRT5.
Ke F, Ren C, Zhai Z, Gao X, Wei J, Zhu Y, Zhi Y., Free PMC Article | 05/7/2022 |
| SIRT5 functions as a tumor suppressor in renal cell carcinoma by reversing the Warburg effect. | SIRT5 functions as a tumor suppressor in renal cell carcinoma by reversing the Warburg effect.
Yihan L, Xiaojing W, Ao L, Chuanjie Z, Haofei W, Yan S, Hongchao H., Free PMC Article | 03/26/2022 |
| SIRT5 IS A DRUGGABLE METABOLIC VULNERABILITY IN ACUTE MYELOID LEUKEMIA. | SIRT5 IS A DRUGGABLE METABOLIC VULNERABILITY IN ACUTE MYELOID LEUKEMIA.
Yan D, Franzini A, Pomicter AD, Halverson BJ, Antelope O, Mason CC, Ahmann JM, Senina AV, Vellore NA, Jones CL, Zabriskie MS, Than H, Xiao MJ, van Scoyk A, Patel AB, Clair PM, Heaton WL, Owen SC, Andersen JL, Egbert CM, Reisz JA, D'Alessandro A, Cox JE, Gantz KC, Redwine HM, Iyer SM, Khorashad JS, Rajabi N, Olsen CA, O'Hare T, Deininger MW., Free PMC Article | 03/19/2022 |
| SIRT5 Directly Inhibits the PI3K/AKT Pathway in Prostate Cancer Cell Lines. | SIRT5 Directly Inhibits the PI3K/AKT Pathway in Prostate Cancer Cell Lines.
Choi SY, Jeon JM, Na AY, Kwon OK, Bang IH, Ha YS, Bae EJ, Park BH, Lee EH, Kwon TG, Lee JN, Lee S., Free PMC Article | 03/12/2022 |
| Sirtuin 5 promotes arterial thrombosis by blunting the fibrinolytic system. | Sirtuin 5 promotes arterial thrombosis by blunting the fibrinolytic system.
Liberale L, Akhmedov A, Vlachogiannis NI, Bonetti NR, Nageswaran V, Miranda MX, Puspitasari YM, Schwarz L, Costantino S, Paneni F, Beer JH, Ruschitzka F, Montecucco F, Lüscher TF, Stamatelopoulos K, Stellos K, Camici GG. | 02/26/2022 |
| Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression. | Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression.
Hu T, Shukla SK, Vernucci E, He C, Wang D, King RJ, Jha K, Siddhanta K, Mullen NJ, Attri KS, Murthy D, Chaika NV, Thakur R, Mulder SE, Pacheco CG, Fu X, High RR, Yu F, Lazenby A, Steegborn C, Lan P, Mehla K, Rotili D, Chaudhary S, Valente S, Tafani M, Mai A, Auwerx J, Verdin E, Tuveson D, Singh PK., Free PMC Article | 01/22/2022 |
| Dysregulation of mitochondrial sirtuin genes is associated with human male infertility. | Dysregulation of mitochondrial sirtuin genes is associated with human male infertility.
Bello JH, Khan MJ, Amir S, Kakakhel HG, Tahir F, Sultan S, Raza SQ, Mamoulakis C, Zachariou A, Tsatsakis A, Sofikitis N, Shah STA. | 01/15/2022 |
| Role of mitochondrial sirtuins in rheumatoid arthritis. | Role of mitochondrial sirtuins in rheumatoid arthritis.
Hussain MZ, Haris MS, Khan MS, Mahjabeen I. | 01/8/2022 |
| The role of SIRT5 and p53 proteins in the sensitivity of colon cancer cells to chemotherapeutic agent 5-Fluorouracil. | The role of SIRT5 and p53 proteins in the sensitivity of colon cancer cells to chemotherapeutic agent 5-Fluorouracil.
Ekremoglu O, Koc A. | 01/8/2022 |
| Dysregulation of the Sirt5/IDH2 axis contributes to sunitinib resistance in human renal cancer cells. | Dysregulation of the Sirt5/IDH2 axis contributes to sunitinib resistance in human renal cancer cells.
Meng L, Chen D, Meng G, Lu L, Han C., Free PMC Article | 01/1/2022 |
| Mitochondrial sirtuins genetic variations and gastric cancer risk: Evidence from retrospective observational study. | Mitochondrial sirtuins genetic variations and gastric cancer risk: Evidence from retrospective observational study.
Mahjabeen I, Rizwan M, Fareen G, Waqar Ahmed M, Farooq Khan A, Akhtar Kayani M. | 10/23/2021 |
| The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics. | The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics.
Giblin W, Bringman-Rodenbarger L, Guo AH, Kumar S, Monovich AC, Mostafa AM, Skinner ME, Azar M, Mady AS, Chung CH, Kadambi N, Melong KA, Lee HJ, Zhang L, Sajjakulnukit P, Trefely S, Varner EL, Iyer S, Wang M, Wilmott JS, Soyer HP, Sturm RA, Pritchard AL, Andea AA, Scolyer RA, Stark MS, Scott DA, Fullen DR, Bosenberg MW, Chandrasekaran S, Nikolovska-Coleska Z, Verhaegen ME, Snyder NW, Rivera MN, Osterman AL, Lyssiotis CA, Lombard DB., Free PMC Article | 10/9/2021 |