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    SIRT3 sirtuin 3 [ Homo sapiens (human) ]

    Gene ID: 23410, updated on 24-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Sex-related differences in SIRT3-mediated mitochondrial dynamics in renal ischemia/reperfusion injury.

    Sex-related differences in SIRT3-mediated mitochondrial dynamics in renal ischemia/reperfusion injury.
    Yao H, Zhao H, Du Y, Zhang Y, Li Y, Zhu H.

    06/21/2024
    SIRT3 and SIRT4 double-genes remodeled the mitochondrial network to induce hepatocellular carcinoma cell line differentiation and suppress malignant phenotypes.

    SIRT3 and SIRT4 double-genes remodeled the mitochondrial network to induce hepatocellular carcinoma cell line differentiation and suppress malignant phenotypes.
    Zhang L, Dai Z, Shi S, Yan Z, Yang J, Xue W, He Y, Mi S, Cheng C, Wang L, Li N, Tan W, Jiang Z, Sun H, Li S.

    04/25/2024
    Sirtuin 3 regulates astrocyte activation by reducing Notch1 signaling after status epilepticus.

    Sirtuin 3 regulates astrocyte activation by reducing Notch1 signaling after status epilepticus.
    Zhu J, Park S, Kim SH, Kim CH, Jeong KH, Kim WJ.

    04/24/2024
    The protective mechanism of SIRT3 and potential therapy in acute kidney injury.

    The protective mechanism of SIRT3 and potential therapy in acute kidney injury.
    Yuan J, Zhao J, Qin Y, Zhang Y, Wang A, Ma R, Han M, Hui Y, Guo S, Ning X, Sun S.

    04/17/2024
    Sirt3 Protects Retinal Pigment Epithelial Cells From High Glucose-Induced Injury by Promoting Mitophagy Through the AMPK/mTOR/ULK1 Pathway.

    Sirt3 Protects Retinal Pigment Epithelial Cells From High Glucose-Induced Injury by Promoting Mitophagy Through the AMPK/mTOR/ULK1 Pathway.
    Yang W, Qiu C, Lv H, Zhang Z, Yao T, Huang L, Wu G, Zhang X, Chen J, He Y., Free PMC Article

    04/4/2024
    Role of Argininosuccinate Synthase 1 -Dependent L-Arginine Biosynthesis in the Protective Effect of Endothelial Sirtuin 3 Against Atherosclerosis.

    Role of Argininosuccinate Synthase 1 -Dependent L-Arginine Biosynthesis in the Protective Effect of Endothelial Sirtuin 3 Against Atherosclerosis.
    Cao X, Wu VWY, Han Y, Hong H, Wu Y, Kong APS, Lui KO, Tian XY., Free PMC Article

    03/28/2024
    Targeting SIRT3 sensitizes glioblastoma to ferroptosis by promoting mitophagy and inhibiting SLC7A11.

    Targeting SIRT3 sensitizes glioblastoma to ferroptosis by promoting mitophagy and inhibiting SLC7A11.
    Li X, Zhang W, Xing Z, Hu S, Zhang G, Wang T, Wang T, Fan Q, Chen G, Cheng J, Jiang X, Cai R., Free PMC Article

    03/8/2024
    SIRT3 Activation a Promise in Drug Development? New Insights into SIRT3 Biology and Its Implications on the Drug Discovery Process.

    SIRT3 Activation a Promise in Drug Development? New Insights into SIRT3 Biology and Its Implications on the Drug Discovery Process.
    Lambona C, Zwergel C, Valente S, Mai A., Free PMC Article

    02/23/2024
    Sirtuin3 promotes the degradation of hepatic Z alpha-1 antitrypsin through lipophagy.

    Sirtuin3 promotes the degradation of hepatic Z alpha-1 antitrypsin through lipophagy.
    Poole B, Oshins R, Huo Z, Aranyos A, West J, Duarte S, Clark VC, Beduschi T, Zarrinpar A, Brantly M, Khodayari N., Free PMC Article

    02/21/2024
    Context-dependent role of SIRT3 in cancer.

    Context-dependent role of SIRT3 in cancer.
    Zhang J, Ye J, Zhu S, Han B, Liu B.

    02/7/2024
    Reduced SIRT1 and SIRT3 and Lower Antioxidant Capacity of Seminal Plasma Is Associated with Shorter Sperm Telomere Length in Oligospermic Men.

    Reduced SIRT1 and SIRT3 and Lower Antioxidant Capacity of Seminal Plasma Is Associated with Shorter Sperm Telomere Length in Oligospermic Men.
    Dhillon VS, Shahid M, Deo P, Fenech M., Free PMC Article

    01/31/2024
    Melatonin attenuates sepsis-induced acute kidney injury by promoting mitophagy through SIRT3-mediated TFAM deacetylation.

    Melatonin attenuates sepsis-induced acute kidney injury by promoting mitophagy through SIRT3-mediated TFAM deacetylation.
    Deng Z, He M, Hu H, Zhang W, Zhang Y, Ge Y, Ma T, Wu J, Li L, Sun M, An S, Li J, Huang Q, Gong S, Zhang J, Chen Z, Zeng Z., Free PMC Article

    01/6/2024
    Evaluation of ARK5 and SIRT3 expression in renal cell carcinoma and their clinical significance.

    Evaluation of ARK5 and SIRT3 expression in renal cell carcinoma and their clinical significance.
    Elkady N, Aldesoky AI, Dawoud MM., Free PMC Article

    11/28/2023
    SIRT3 Is a Critical Regulator of Mitochondrial Function of Fibroblasts in Pulmonary Hypertension.

    SIRT3 Is a Critical Regulator of Mitochondrial Function of Fibroblasts in Pulmonary Hypertension.
    Li M, Plecitá-Hlavatá L, Dobrinskikh E, McKeon BA, Gandjeva A, Riddle S, Laux A, Prasad RR, Kumar S, Tuder RM, Zhang H, Hu CJ, Stenmark KR., Free PMC Article

    11/2/2023
    LINC00922 decoys SIRT3 to facilitate the metastasis of colorectal cancer through up-regulation the H3K27 crotonylation of ETS1 promoter.

    LINC00922 decoys SIRT3 to facilitate the metastasis of colorectal cancer through up-regulation the H3K27 crotonylation of ETS1 promoter.
    Liao M, Sun X, Zheng W, Wu M, Wang Y, Yao J, Ma Y, Gao S, Pei D., Free PMC Article

    10/5/2023
    Alterations of SIRT1/SIRT3 subcellular distribution in aging undermine cardiometabolic homeostasis during ischemia and reperfusion.

    Alterations of SIRT1/SIRT3 subcellular distribution in aging undermine cardiometabolic homeostasis during ischemia and reperfusion.
    Zhang J, Wang H, Slotabec L, Cheng F, Tan Y, Li J., Free PMC Article

    09/14/2023
    LncRNA LINC01197 inhibited the formation of calcium oxalate-induced kidney stones by regulating miR-516b-5p/SIRT3/FOXO1 signaling pathway.

    LncRNA LINC01197 inhibited the formation of calcium oxalate-induced kidney stones by regulating miR-516b-5p/SIRT3/FOXO1 signaling pathway.
    Xi J, Chen Y, Jing J, Qi W, Zhang Y.

    08/25/2023
    The lncRNA HOTAIR attenuates pyroptosis of diabetic cardiomyocytes by recruiting FUS to regulate SIRT3 expression.

    The lncRNA HOTAIR attenuates pyroptosis of diabetic cardiomyocytes by recruiting FUS to regulate SIRT3 expression.
    Xiong J, Zhou Q.

    08/25/2023
    SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes.

    SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes.
    Chang Y, Wang C, Zhu J, Zheng S, Sun S, Wu Y, Jiang X, Li L, Ma R, Li G., Free PMC Article

    07/27/2023
    SIRT3-and FAK-mediated acetylation-phosphorylation crosstalk of NFATc1 regulates N[epsilon]-carboxymethyl-lysine-induced vascular calcification in diabetes mellitus.

    SIRT3-and FAK-mediated acetylation-phosphorylation crosstalk of NFATc1 regulates N(ε)-carboxymethyl-lysine-induced vascular calcification in diabetes mellitus.
    Sun Z, Zhang L, Yin K, Zang G, Qian Y, Mao X, Li L, Jing Q, Wang Z.

    07/25/2023
    Radiation resistance of cancer cells caused by mitochondrial dysfunction depends on SIRT3-mediated mitophagy.

    Radiation resistance of cancer cells caused by mitochondrial dysfunction depends on SIRT3-mediated mitophagy.
    Wei Y, Xiao G, Xu H, Sun X, Shi Y, Wang F, Kang J, Peng J, Zhou F.

    07/21/2023
    Changes of energy metabolism in failing heart and its regulation by SIRT3.

    Changes of energy metabolism in failing heart and its regulation by SIRT3.
    Wang X, Huang Y, Zhang K, Chen F, Nie T, Zhao Y, He F, Ni J.

    06/26/2023
    SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.

    SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.
    Huang P, Zhao H, Pan X, Li J, Pan W, Dai H, Wang J, Xia C, Liu F.

    06/25/2023
    Role of SIRT3 in mitochondrial biology and its therapeutic implications in neurodegenerative disorders.

    Role of SIRT3 in mitochondrial biology and its therapeutic implications in neurodegenerative disorders.
    Mishra Y, Kaundal RK.

    06/7/2023
    Sirtuin3 Alleviated Influenza A Virus-Induced Mitochondrial Oxidative Stress and Inflammation in Lung Epithelial Cells via Regulating Poly (ADP-Ribose) Polymerase 1 Activity.

    Sirtuin3 Alleviated Influenza A Virus-Induced Mitochondrial Oxidative Stress and Inflammation in Lung Epithelial Cells via Regulating Poly (ADP-Ribose) Polymerase 1 Activity.
    Yuan J, Li R, Song H, Liu X.

    06/2/2023
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