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    ITGB3BP integrin subunit beta 3 binding protein [ Homo sapiens (human) ]

    Gene ID: 23421, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Integrated profiling identifies ITGB3BP as prognostic biomarker for hepatocellular carcinoma.

    Integrated profiling identifies ITGB3BP as prognostic biomarker for hepatocellular carcinoma.
    Liang Q, Tan C, Xiao F, Yin F, Liu M, Lei L, Wu L, Yang Y, Tan HJJ, Liu S, Zeng X., Free PMC Article

    01/29/2022
    beta3-Endonexin interacts with ninein in vascular endothelial cells to promote angiogenesis.

    β3-Endonexin interacts with ninein in vascular endothelial cells to promote angiogenesis.
    Cao Z, Ge S, Xu Z, Ma YQ.

    11/22/2021
    Identification of genes in hepatocellular carcinoma induced by non-alcoholic fatty liver disease.

    Identification of genes in hepatocellular carcinoma induced by non-alcoholic fatty liver disease.
    Cai C, Song X, Yu C., Free PMC Article

    06/12/2021
    The beta3-endonexin can act as a novel anti-angiogenic factor specifically in the response to hypoxia due to its negative impact on the activation of HIF-1.

    The β3-integrin binding protein β3-endonexin is a novel negative regulator of hypoxia-inducible factor-1.
    Kračun D, Riess F, Kanchev I, Gawaz M, Görlach A., Free PMC Article

    02/28/2015
    Data propose that CENP-P/O/R/Q/U self-assembles on kinetochores with varying stoichiometry and undergoes a pre-mitotic maturation step that could be important for kinetochores switching into the correct conformation for microtubule-attachment.

    Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U kinetochore sub-complex.
    Eskat A, Deng W, Hofmeister A, Rudolphi S, Emmerth S, Hellwig D, Ulbricht T, Döring V, Bancroft JM, McAinsh AD, Cardoso MC, Meraldi P, Hoischen C, Leonhardt H, Diekmann S., Free PMC Article

    03/9/2013
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
    findings suggest that NRIF3-Ser28 is a physiologic target of Pak1 signaling and contributes to the enhanced NRIF3 co-activator activity, leading to coordinated potentiation of ERalpha transactivation

    Serine 28 phosphorylation of NRIF3 confers its co-activator function for estrogen receptor-alpha transactivation.
    Talukder AH, Li DQ, Manavathi B, Kumar R., Free PMC Article

    01/21/2010
    Results suggest that breast cancer cells contain a novel "death switch" that can be specifically triggered by NRIF3 or death domain 1.

    The NRIF3 family of transcriptional coregulators induces rapid and profound apoptosis in breast cancer cells.
    Li D, Das S, Yamada T, Samuels HH., Free PMC Article

    01/21/2010
    This protein downregulates urokinase-type plasminogen activator receptor promoter activity.

    Role of beta(3)-endonexin in the regulation of NF-kappaB-dependent expression of urokinase-type plasminogen activator receptor.
    Besta F, Massberg S, Brand K, Müller E, Page S, Grüner S, Lorenz M, Sadoul K, Kolanus W, Lengyel E, Gawaz M.

    01/21/2010
    Metastasis-associated protein 1 interacts with NRIF3, an estrogen-inducible nuclear receptor coregulator

    Metastasis-associated protein 1 interacts with NRIF3, an estrogen-inducible nuclear receptor coregulator.
    Talukder AH, Gururaj A, Mishra SK, Vadlamudi RK, Kumar R., Free PMC Article

    01/21/2010
    The presence of various isoforms and the relationship between subcellular localization and integrin-activating function of beta(3)-endonexin is described.

    Novel alternatively spliced form of beta(3)-endonexin.
    Fujimoto TT, Katsutani S, Shimomura T, Fujimura K.

    01/21/2010
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