| ANGPTL2 promotes VEGF-A synthesis in human lung cancer and facilitates lymphangiogenesis. | ANGPTL2 promotes VEGF-A synthesis in human lung cancer and facilitates lymphangiogenesis.
Liu PI, Jiang YJ, Chang AC, Huang CL, Fong YC, Guo JH, Liu CL, Wang SW, Liu JF, Chang SL, Tang CH., Free PMC Article | 03/27/2023 |
| Angiopoietin-like protein 2 deficiency promotes periodontal inflammation and alveolar bone loss. | Angiopoietin-like protein 2 deficiency promotes periodontal inflammation and alveolar bone loss.
Jiang C, Yao S, Guo Y, Ma L, Wang X, Chen Y, Zhang H, Cao Z. | 11/5/2022 |
| Angptl2 is a Marker of Cellular Senescence: The Physiological and Pathophysiological Impact of Angptl2-Related Senescence. | Angptl2 is a Marker of Cellular Senescence: The Physiological and Pathophysiological Impact of Angptl2-Related Senescence.
Thorin-Trescases N, Labbé P, Mury P, Lambert M, Thorin E., Free PMC Article | 12/18/2021 |
| Angiopoietin-like 2 is a potential biomarker for diabetic foot patients. | Angiopoietin-like 2 is a potential biomarker for diabetic foot patients.
Wang Y, Zheng Z, Yang Y, Lang J, Zhang N, Yang L, Zhao D., Free PMC Article | 10/2/2021 |
| Vitreous levels of vascular endothelial growth factor, stromal cell-derived factor-1alpha, and angiopoietin-like protein 2 in patients with active proliferative diabetic retinopathy. | Vitreous levels of vascular endothelial growth factor, stromal cell-derived factor-1α, and angiopoietin-like protein 2 in patients with active proliferative diabetic retinopathy.
Keles A, Sonmez K, Erol YO, Ayyıldız SN, Ogus E. | 09/25/2021 |
| Angiopoietin-like protein 2 decreases peritoneal metastasis of ovarian cancer cells by suppressing anoikis resistance. | Angiopoietin-like protein 2 decreases peritoneal metastasis of ovarian cancer cells by suppressing anoikis resistance.
Takeshita Y, Motohara T, Kadomatsu T, Doi T, Obayashi K, Oike Y, Katabuchi H, Endo M. | 09/18/2021 |
| CSN5 Promotes Carcinogenesis of Thyroid Carcinoma Cells Through ANGPTL2. | CSN5 Promotes Carcinogenesis of Thyroid Carcinoma Cells Through ANGPTL2.
Xie P, Wang H, Fang J, Du D, Tian Z, Zhen J, Liu Y, Ding Y, Fu B, Liu F, Huang D, Yu J. | 09/11/2021 |
| Circulating angiopoietin-like protein 2 levels and arterial stiffness in patients receiving maintenance hemodialysis: A cross-sectional study. | Circulating angiopoietin-like protein 2 levels and arterial stiffness in patients receiving maintenance hemodialysis: A cross-sectional study.
Fukami H, Morinaga J, Okadome Y, Nishiguchi Y, Iwata Y, Kanki T, Nakagawa T, Izumi Y, Kakizoe Y, Kuwabara T, Horiguchi H, Sato M, Kadomatsu T, Miyata K, Tajiri T, Oike Y, Mukoyama M. | 08/28/2021 |
| Knockdown of ANGPTL2 Protects Renal Tubular Epithelial Cells Against Hypoxia/Reoxygenation-Induced Injury via Suppressing TLR4/NF-kappaB Signaling Pathway and Activating Nrf2/HO-1 Signaling Pathway. | Knockdown of ANGPTL2 Protects Renal Tubular Epithelial Cells Against Hypoxia/Reoxygenation-Induced Injury via Suppressing TLR4/NF-κB Signaling Pathway and Activating Nrf2/HO-1 Signaling Pathway.
Xiang H, Xue W, Li Y, Zheng J, Ding C, Dou M, Wu X., Free PMC Article | 07/24/2021 |
| Myositis ossificans-like soft tissue aneurysmal bone cyst: a clinical, radiological, and pathological study of seven cases with COL1A1-USP6 fusion and a novel ANGPTL2-USP6 fusion. | Myositis ossificans-like soft tissue aneurysmal bone cyst: a clinical, radiological, and pathological study of seven cases with COL1A1-USP6 fusion and a novel ANGPTL2-USP6 fusion.
Zhang L, Hwang S, Benayed R, Zhu GG, Mullaney KA, Rios KM, Sukhadia PY, Agaram N, Zhang Y, Bridge JA, Healey JH, Athanasian EA, Hameed M., Free PMC Article | 07/10/2021 |
| TGF-beta1 aggravates degenerative nucleus pulposus cells inflammation and fibrosis through the upregulation of angiopoietin-like protein 2 expression. | TGF-β1 aggravates degenerative nucleus pulposus cells inflammation and fibrosis through the upregulation of angiopoietin-like protein 2 expression.
Cui L, Wei H, Li ZM, Dong XB, Wang PY. | 06/26/2021 |
| Anti-inflammatory activity of berberine in non-alcoholic fatty liver disease via the Angptl2 pathway. | Anti-inflammatory activity of berberine in non-alcoholic fatty liver disease via the Angptl2 pathway.
Lu Z, He B, Chen Z, Yan M, Wu L., Free PMC Article | 06/5/2021 |
| Angiopoietin-like protein 2 as a novel marker for patients with primary Sjogren's syndrome-related interstitial lung disease. | Angiopoietin-like protein 2 as a novel marker for patients with primary Sjogren's syndrome-related interstitial lung disease.
Shi L, Fu Q, Chen N, Liu R, Zheng Y. | 05/29/2021 |
| Stroma-derived ANGPTL2 establishes an anti-tumor microenvironment during intestinal tumorigenesis. | Stroma-derived ANGPTL2 establishes an anti-tumor microenvironment during intestinal tumorigenesis.
Horiguchi H, Kadomatsu T, Miyata K, Terada K, Sato M, Torigoe D, Morinaga J, Moroishi T, Oike Y. | 04/17/2021 |
| Association of serum angiopoietin-like protein 2 with elevated risk of cardiovascular diseases in subjects with type 2 diabetes. | Association of serum angiopoietin-like protein 2 with elevated risk of cardiovascular diseases in subjects with type 2 diabetes.
El-Lebedy D. | 04/13/2021 |
| Circulating angiopoietin-like protein 2 levels and mortality risk in patients receiving maintenance hemodialysis: a prospective cohort study. | Circulating angiopoietin-like protein 2 levels and mortality risk in patients receiving maintenance hemodialysis: a prospective cohort study.
Morinaga J, Kakuma T, Fukami H, Hayata M, Uchimura K, Mizumoto T, Kakizoe Y, Miyoshi T, Shiraishi N, Adachi M, Izumi Y, Kuwabara T, Okadome Y, Sato M, Horiguchi H, Sugizaki T, Kadomatsu T, Miyata K, Tajiri S, Tajiri T, Tomita K, Kitamura K, Oike Y, Mukoyama M. | 11/21/2020 |
| Characterization of Tumor Blood Vasculature Expression of Human Invasive Bladder Cancer by Laser Capture Microdissection and Transcriptional Profiling. | Characterization of Tumor Blood Vasculature Expression of Human Invasive Bladder Cancer by Laser Capture Microdissection and Transcriptional Profiling.
Roudnicky F, Poyet C, Buser L, Saba K, Wild P, Otto VI, Detmar M. | 09/26/2020 |
| this work suggests that tumor cell-derived ANGPTL2 accelerates activities associated with glycolytic metabolism in lung cancer cells by activating TGF-beta-ZEB1-GLUT3 signaling. | Tumor cell-derived angiopoietin-like protein 2 establishes a preference for glycolytic metabolism in lung cancer cells.
Osumi H, Horiguchi H, Kadomatsu T, Tashiro K, Morinaga J, Takahashi T, Ikeda K, Ito T, Suzuki M, Endo M, Oike Y., Free PMC Article | 04/25/2020 |
| In younger patients with lower levels of tissue inflammation and arterial senescence load, ANGPTL2 decreased after cardiac surgery, suggesting that circulating ANGPTL2 reflects tissue inflammation and senescence. | Reduction of plasma angiopoietin-like 2 after cardiac surgery is related to tissue inflammation and senescence status of patients.
Noly PE, Labbé P, Thorin-Trescases N, Fortier A, Nguyen A, Thorin E, Carrier M. | 03/7/2020 |
| ANGPTL2 secreted by human chondrocytes plays a negative role in the pathogenesis of osteoarthritis. | Angiopoietin-like 2 upregulation promotes human chondrocyte injury via NF-κB and p38/MAPK signaling pathway.
Shan W, Cheng C, Huang W, Ding Z, Luo S, Cui G, Lu W, Liu F, Xu J, He W, Yin Z. | 02/15/2020 |
| ANGPTL2 might be directly involved in podocyte dysfunction and independently associated with the progression of Diabetic Kidney Disease stages | Angiopoietin-Like Protein 2 Promotes the Progression of Diabetic Kidney Disease.
Ishii T, Furuya F, Takahashi K, Shikata M, Takamura T, Kobayashi H, Miyazaki A, Morinaga J, Terada K, Oike Y, Kanda E, Kitamura K. | 12/7/2019 |
| Enhanced ANGPTL2 expression in adipose tissues is associated with insulin resistance in obese women. | Enhanced ANGPTL2 expression in adipose tissues and its association with insulin resistance in obese women.
Kim J, Lee SK, Jang YJ, Park HS, Kim JH, Hong JP, Lee YJ, Heo YS., Free PMC Article | 11/16/2019 |
| Studied association of promoter methylation of angiopoietin like 2 (ANGPTL2) in coronary heart disease (CHD) and found that in females, lower methylation in the promoter region of the ANGPTL2 gene is associated with CHD. | Preliminary study of the relationship between promoter methylation of the ANGPTL2 gene and coronary heart disease.
Zhou J, Chen L, Yang X, Huang X, Wang Z, Peng P, Lian J., Free PMC Article | 05/4/2019 |
| Circulating ANGPTL2 levels increase in HF patients. Increased circulating ANGPTL2 levels in HF patients reflect, rather than promote, cardiac dysfunction. | Circulating ANGPTL2 Levels Increase in Humans and Mice Exhibiting Cardiac Dysfunction.
Tian Z, Miyata K, Morinaga J, Horiguchi H, Kadomatsu T, Endo M, Zhao J, Zhu S, Sugizaki T, Sato M, Terada K, Okumura T, Murohara T, Oike Y. | 02/23/2019 |
| Plasma level of Angptl2 increases in arteriosclerotic occlusion patients. Its level is remarkably increased when the disease progressions to critical limb ischemia. | Change of Serum Angiopoietin-like Protein 2 and Its Significance in Patients with Arteriosclerotic Occlusion.
Liang Y, Nie H, Ren H, Li F, Tian C, Li H, Zheng Y. | 02/9/2019 |