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    FOS Fos proto-oncogene, AP-1 transcription factor subunit [ Homo sapiens (human) ]

    Gene ID: 2353, updated on 28-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Lack of FOS/FOSB Gene Rearrangements in Ischemic Fasciitis Indicates Distinct Pathogenesis from Proliferative Fasciitis and Proliferative Myositis.

    Lack of FOS/FOSB Gene Rearrangements in Ischemic Fasciitis Indicates Distinct Pathogenesis from Proliferative Fasciitis and Proliferative Myositis.
    Zilla ML, Naous R, John I.

    06/25/2024
    Single cell RNA-seq identifies a FOS/JUN-related monocyte signature associated with clinical response of heart failure patients with mesenchymal stem cell therapy.

    Single cell RNA-seq identifies a FOS/JUN-related monocyte signature associated with clinical response of heart failure patients with mesenchymal stem cell therapy.
    Yuan H, Zhang P, Xin Y, Liu Z, Gao B., Free PMC Article

    04/12/2024
    Iron overload promotes the progression of MLL-AF9 induced acute myeloid leukemia by upregulation of FOS.

    Iron overload promotes the progression of MLL-AF9 induced acute myeloid leukemia by upregulation of FOS.
    Yang F, Cui X, Wang H, Zhang D, Luo S, Li Y, Dai Y, Yang D, Zhang X, Wang L, Zheng G, Zhang X.

    02/6/2024
    Expression of PVRL4, a molecular target for cancer treatment, is transcriptionally regulated by FOS.

    Expression of PVRL4, a molecular target for cancer treatment, is transcriptionally regulated by FOS.
    Nanamiya T, Takane K, Yamaguchi K, Okawara Y, Arakawa M, Saku A, Ikenoue T, Fujiyuki T, Yoneda M, Kai C, Furukawa Y., Free PMC Article

    01/10/2024
    Molecular profiling of clinical remission in psoriatic arthritis reveals dysregulation of FOS and CCDC50 genes: a gene expression study.

    Molecular profiling of clinical remission in psoriatic arthritis reveals dysregulation of FOS and CCDC50 genes: a gene expression study.
    Angioni MM, Floris A, Cangemi I, Congia M, Chessa E, Naitza MR, Piga M, Cauli A., Free PMC Article

    11/20/2023
    Suppressing c-FOS expression by G-quadruplex ligands inhibits osimertinib-resistant non-small cell lung cancer.

    Suppressing c-FOS expression by G-quadruplex ligands inhibits osimertinib-resistant non-small cell lung cancer.
    Lu K, Wang HC, Tu YC, Chang CC, Lou PJ, Chang TC, Lin JJ.

    11/15/2023
    Over-expression of cFos by the Transcription Factors NFATc2 and Sp1 in Pancreatic Cancer Cells.

    Over-expression of cFos by the Transcription Factors NFATc2 and Sp1 in Pancreatic Cancer Cells.
    Malsy M, Graf B, Bruendl E, Maier-Stocker C, Bundscherer A.

    11/3/2023
    New kids on the block: FOS and FOSB gene.

    New kids on the block: FOS and FOSB gene.
    Cordier F, Creytens D.

    10/28/2023
    Overexpression of MiR-181c-5p Attenuates Human Umbilical Vascular Endothelial Cell Injury in Deep Vein Thrombosis by Targeting FOS.

    Overexpression of MiR-181c-5p Attenuates Human Umbilical Vascular Endothelial Cell Injury in Deep Vein Thrombosis by Targeting FOS.
    Yang F, Chen D, Liu Y, Zhang X, Su Y, Zhang X, Yin Z, Wu J.

    10/25/2023
    Protection of c-Fos from autophagic degradation by PRMT1-mediated methylation fosters gastric tumorigenesis.

    Protection of c-Fos from autophagic degradation by PRMT1-mediated methylation fosters gastric tumorigenesis.
    Kim E, Rahmawati L, Aziz N, Kim HG, Kim JH, Kim KH, Yoo BC, Parameswaran N, Kang JS, Hur H, Manavalan B, Lee J, Cho JY., Free PMC Article

    08/16/2023
    c-FOS is an integral component of the IKZF1 transactivator complex and mediates lenalidomide resistance in multiple myeloma.

    c-FOS is an integral component of the IKZF1 transactivator complex and mediates lenalidomide resistance in multiple myeloma.
    Osada N, Kikuchi J, Iha H, Yasui H, Ikeda S, Takahashi N, Furukawa Y., Free PMC Article

    08/16/2023
    Metabolic rewiring controlled by c-Fos governs cartilage integrity in osteoarthritis.

    Metabolic rewiring controlled by c-Fos governs cartilage integrity in osteoarthritis.
    Matsuoka K, Bakiri L, Bilban M, Toegel S, Haschemi A, Yuan H, Kasper M, Windhager R, Wagner EF., Free PMC Article

    08/16/2023
    Loss of function of GATA3 regulates FRA1 and c-FOS to activate EMT and promote mammary tumorigenesis and metastasis.

    Loss of function of GATA3 regulates FRA1 and c-FOS to activate EMT and promote mammary tumorigenesis and metastasis.
    Liu X, Bai F, Wang Y, Wang C, Chan HL, Zheng C, Fang J, Zhu WG, Pei XH., Free PMC Article

    06/30/2023
    C-Fos-activated circRPPH1 contributes to glioma stemness.

    C-Fos-activated circRPPH1 contributes to glioma stemness.
    Xu G, Qu J, Zhang M, Wang Q.

    04/26/2023
    Toll-Like Receptor Signaling in the Pathogenesis of Chronic Dacryocystitis: Implication of c-FOS Transcription Factor and its Downstream Effector Chemokine Genes CCL2, CCL4, CXCL3, CXCR4 with a Shift of the M1/M2 Macrophage Phenotype.

    Toll-Like Receptor Signaling in the Pathogenesis of Chronic Dacryocystitis: Implication of c-FOS Transcription Factor and its Downstream Effector Chemokine Genes CCL2, CCL4, CXCL3, CXCR4 with a Shift of the M1/M2 Macrophage Phenotype.
    Edris NA, Aboulhoda BE, El-Din SS, Fouad AM, Albadawi E, Rashed LA, Elessawy KB.

    03/9/2023
    Inflammatory lobular hemangioma (T-cell-rich angiomatoid polypoid pseudolymphoma)-Assessment of FOS/FOSB and lymphoid markers and comparison with epithelioid hemangioma.

    Inflammatory lobular hemangioma (T-cell-rich angiomatoid polypoid pseudolymphoma)-Assessment of FOS/FOSB and lymphoid markers and comparison with epithelioid hemangioma.
    Vargas AC, Maclean FM, Tsu KY, Ma L, Moir D.

    12/10/2022
    c-FOS Expression Analysis in Pterygia Cell Spot Arrays.

    c-FOS Expression Analysis in Pterygia Cell Spot Arrays.
    Mastronikolis S, Tsiambas E, Pagkalou M, Makri OE, Thomopoulou VK, Peschos D, Ragos V, Roukas D, Georgakopoulos CD., Free PMC Article

    10/1/2022
    Combinatorial Treatment with PARP-1 Inhibitors and Cisplatin Attenuates Cervical Cancer Growth through Fos-Driven Changes in Gene Expression.

    Combinatorial Treatment with PARP-1 Inhibitors and Cisplatin Attenuates Cervical Cancer Growth through Fos-Driven Changes in Gene Expression.
    Gupte R, Lin KY, Nandu T, Lea JS, Kraus WL., Free PMC Article

    08/13/2022
    Interleukin-1beta activated c-FOS transcription factor binds preferentially to a specific allele of the matrix metalloproteinase-13 promoter and increases susceptibility to endometriosis.

    Interleukin-1β activated c-FOS transcription factor binds preferentially to a specific allele of the matrix metalloproteinase-13 promoter and increases susceptibility to endometriosis.
    Pandit A, Das Mahapatra P, Saha P, Srivastava AK, Swarnakar S.

    07/23/2022
    FOS gene associated immune infiltration signature in perivascular adipose tissues of abdominal aortic aneurysm.

    FOS gene associated immune infiltration signature in perivascular adipose tissues of abdominal aortic aneurysm.
    Ding S, Gan T, Xiang Y, Zhu X, Jin Y, Ning H, Guo T, Zhao S, Xie J, Yuan Z.

    06/11/2022
    Role of Innate Immune Regulatory Genes, FOXP3 and FOS in Chronic Hepatitis B Infection.

    Role of Innate Immune Regulatory Genes, FOXP3 and FOS in Chronic Hepatitis B Infection.
    Borkakoty B, Sarmah MD, Majumdar T, Bhattacharjee CK, Baruah PJ, Biswas D, Kaur H.

    05/28/2022
    LncRNA CRART16/miR-122-5p/FOS axis promotes angiogenesis of gastric cancer by upregulating VEGFD expression.

    LncRNA CRART16/miR-122-5p/FOS axis promotes angiogenesis of gastric cancer by upregulating VEGFD expression.
    Zhang J, Pang X, Lei L, Zhang J, Zhang X, Chen Z, Zhu J, Jiang Y, Chen G, Wu Y, Wu T, Pan Y, Liu Y, Cui Y, Wang X., Free PMC Article

    05/28/2022
    Integrative epigenomic profiling reveal AP-1 is a key regulator in intrahepatich cholangiocarcinoma.

    Integrative epigenomic profiling reveal AP-1 is a key regulator in intrahepatich cholangiocarcinoma.
    He K, Feng Y, An S, Liu F, Xiang G.

    04/9/2022
    Regulation of c-Fos gene transcription by stimulus-responsive protein kinases.

    Regulation of c-Fos gene transcription by stimulus-responsive protein kinases.
    Dalhäusser AK, Rössler OG, Thiel G.

    03/19/2022
    Topoisomerase IIalpha represses transcription by enforcing promoter-proximal pausing.

    Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing.
    Herrero-Ruiz A, Martínez-García PM, Terrón-Bautista J, Millán-Zambrano G, Lieberman JA, Jimeno-González S, Cortés-Ledesma F., Free PMC Article

    02/19/2022
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