| In vitro differentiation of human amniotic epithelial stem cells into keratinocytes regulated by OPN3. | In vitro differentiation of human amniotic epithelial stem cells into keratinocytes regulated by OPN3.
Jin S, Zhang W, Zeng W, Zhang Y, Feng J, Wang Y, Luo H, Liu T, Lu H. | 03/1/2024 |
| Opsin 3 expression in human Langerhans cell histiocytosis and its mediation of ELD-1 cellular function. | Opsin 3 expression in human Langerhans cell histiocytosis and its mediation of ELD-1 cellular function.
Ye T, Lan Y, Zhang W, Feng J, Luo H, Zeng W, Wang Y, Mou H, Dong X, Zuo L, Lu H. | 10/13/2023 |
| Opsin 3 mediates UVA-induced keratinocyte supranuclear melanin cap formation. | Opsin 3 mediates UVA-induced keratinocyte supranuclear melanin cap formation.
Lan Y, Zeng W, Wang Y, Dong X, Shen X, Gu Y, Zhang W, Lu H., Free PMC Article | 03/8/2023 |
| The effects of missense OPN3 mutations in melanocytic lesions on protein structure and light-sensitive function. | The effects of missense OPN3 mutations in melanocytic lesions on protein structure and light-sensitive function.
Zhang W, Zeng W, Li P, Feng J, Zhang Y, Jin S, Deng J, Qi S, Lu H. | 12/10/2022 |
| OPN3 Regulates Melanogenesis in Human Congenital Melanocytic Nevus Cells through Functional Interaction with BRAF(V600E). | OPN3 Regulates Melanogenesis in Human Congenital Melanocytic Nevus Cells through Functional Interaction with BRAF(V600E).
Dong X, Zeng W, Zhang W, Lan Y, Wang Y, Feng J, Gu L, Lu H. | 10/29/2022 |
| Identification of OPN3 as associated with non-syndromic oligodontia in a Japanese population. | Identification of OPN3 as associated with non-syndromic oligodontia in a Japanese population.
Inagaki Y, Ogawa T, Tabata MJ, Nagata Y, Watanabe R, Kawamoto T, Moriyama K, Tanaka T. | 12/11/2021 |
| TGFbeta2 Upregulates Tyrosinase Activity through Opsin-3 in Human Skin Melanocytes In Vitro. | TGFβ2 Upregulates Tyrosinase Activity through Opsin-3 in Human Skin Melanocytes In Vitro.
Wang Y, Lan Y, Yang X, Gu Y, Lu H. | 12/11/2021 |
| Expression of OPN3 in acral lentiginous melanoma and its associated with clinicohistopathologic features and prognosis. | Expression of OPN3 in acral lentiginous melanoma and its associated with clinicohistopathologic features and prognosis.
Zeng W, Zhang W, Feng J, He X, Lu H., Free PMC Article | 10/23/2021 |
| Expression of OPN3 in lung adenocarcinoma promotes epithelial-mesenchymal transition and tumor metastasis. | Expression of OPN3 in lung adenocarcinoma promotes epithelial-mesenchymal transition and tumor metastasis.
Xu C, Wang R, Yang Y, Xu T, Li Y, Xu J, Jiang Z., Free PMC Article | 03/6/2021 |
| Opsin3 Downregulation Induces Apoptosis of Human Epidermal Melanocytes via Mitochondrial Pathway. | Opsin3 Downregulation Induces Apoptosis of Human Epidermal Melanocytes via Mitochondrial Pathway.
Wang Y, Lan Y, Lu H., Free PMC Article | 02/13/2021 |
| Illuminating insights into opsin 3 function in the skin. | Illuminating insights into opsin 3 function in the skin.
Olinski LE, Lin EM, Oancea E., Free PMC Article | 02/2/2021 |
| Activation of an Endogenous Opsin 3 Light Receptor Mediates Photo-Relaxation of Pre-Contracting Late Gestation Human Uterine Smooth Muscle Ex Vivo. | Activation of an Endogenous Opsin 3 Light Receptor Mediates Photo-Relaxation of Pre-Contracting Late Gestation Human Uterine Smooth Muscle Ex Vivo.
Yim PD, Hyuga S, Wu AD, Dan W, Vink JY, Gallos G., Free PMC Article | 12/19/2020 |
| OPN3 and MC1R colocalize at both the plasma membrane. | Human nonvisual opsin 3 regulates pigmentation of epidermal melanocytes through functional interaction with melanocortin 1 receptor.
Ozdeslik RN, Olinski LE, Trieu MM, Oprian DD, Oancea E., Free PMC Article | 03/28/2020 |
| This is the first demonstration of photorelaxation in airway smooth muscle via an OPN receptor-mediated pathway. | Airway smooth muscle photorelaxation via opsin receptor activation.
Yim PD, Gallos G, Perez-Zoghbi JF, Zhang Y, Xu D, Wu A, Berkowitz DE, Emala CW., Free PMC Article | 11/16/2019 |
| OPN3 and the multimeric tyrosinase/tyrosinase-related protein complex induced after its activation appear as new potential targets for regulating melanogenesis but also to protect dark skins against blue light in physiological conditions and in pigmentary disorders. | Melanocytes Sense Blue Light and Regulate Pigmentation through Opsin-3.
Regazzetti C, Sormani L, Debayle D, Bernerd F, Tulic MK, De Donatis GM, Chignon-Sicard B, Rocchi S, Passeron T. | 03/30/2019 |
| Decreased OPN3 levels in Bel7402(5-FU) cells activated the anti-apoptotic pathway through increasing phospho-Akt and the Bcl2/Bax ratio, while overexpression of OPN3 inactivated this pathway. | Opsin3 sensitizes hepatocellular carcinoma cells to 5-fluorouracil treatment by regulating the apoptotic pathway.
Jiao J, Hong S, Zhang J, Ma L, Sun Y, Zhang D, Shen B, Zhu C. | 06/23/2012 |
| Polymorphisms in the OPN3 and CHML genes are associated with asthma and atopic asthma. | Identification of a novel asthma susceptibility gene on chromosome 1qter and its functional evaluation.
White JH, Chiano M, Wigglesworth M, Geske R, Riley J, White N, Hall S, Zhu G, Maurio F, Savage T, Anderson W, Cordy J, Ducceschi M, GAIN investigators, Vestbo J, Pillai SG, White JH, Chiano M, Wigglesworth M, Geske R, Riley J, White N, Hall S, Zhu G, Maurio F, Savage T, Anderson W, Cordy J, Ducceschi M, GAIN investigators, Vestbo J, Pillai SG. | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesFollow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis.
McCauley JL, Zuvich RL, Bradford Y, Kenealy SJ, Schnetz-Boutaud N, Gregory SG, Hauser SL, Oksenberg JR, Mortlock DP, Pericak-Vance MA, Haines JL. Identification of a novel asthma susceptibility gene on chromosome 1qter and its functional evaluation.
White JH, Chiano M, Wigglesworth M, Geske R, Riley J, White N, Hall S, Zhu G, Maurio F, Savage T, Anderson W, Cordy J, Ducceschi M, GAIN investigators, Vestbo J, Pillai SG, White JH, Chiano M, Wigglesworth M, Geske R, Riley J, White N, Hall S, Zhu G, Maurio F, Savage T, Anderson W, Cordy J, Ducceschi M, GAIN investigators, Vestbo J, Pillai SG. | 04/3/2008 |
| Assignment of panopsin (OPN3) to human chromosome band 1q43 | Assignment of panopsin (OPN3) to human chromosome band 1q43 by in situ hybridization and somatic cell hybrids.
Halford S, Bellingham J, Ocaka L, Fox M, Johnson S, Foster RG, Hunt DM. | 01/21/2010 |
| Human OPN3 gene consists of six exons and expresses various splice variants. | Different structural organization of the encephalopsin gene in man and mouse.
Kasper G, Taudien S, Staub E, Mennerich D, Rieder M, Hinzmann B, Dahl E, Schwidetzky U, Rosenthal A, Rump A. | 01/21/2010 |
| Related persons with heterozygous germline deletions of 1q42.3, which includes EXO1, RGS7, KMO, CHML, and OPN3, showed no phenotypic abnormalities other than multiple leiomyomatosis. | Germline deletions of EXO1 do not cause colorectal tumors and lesions which are null for EXO1 do not have microsatellite instability.
Alam NA, Gorman P, Jaeger EE, Kelsell D, Leigh IM, Ratnavel R, Murdoch ME, Houlston RS, Aaltonen LA, Roylance RR, Tomlinson IP. | 08/2/2005 |