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    Ets1 E26 avian leukemia oncogene 1, 5' domain [ Mus musculus (house mouse) ]

    Gene ID: 23871, updated on 21-Aug-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    M2 macrophages independently promote beige adipogenesis via blocking adipocyte Ets1.

    M2 macrophages independently promote beige adipogenesis via blocking adipocyte Ets1.
    Wu S, Qiu C, Ni J, Guo W, Song J, Yang X, Sun Y, Chen Y, Zhu Y, Chang X, Sun P, Wang C, Li K, Han X., Free PMC Article

    02/28/2024
    Lysine demethylase KDM3A alleviates hyperoxia-induced bronchopulmonary dysplasia in mice by promoting ETS1 expression.

    Lysine demethylase KDM3A alleviates hyperoxia-induced bronchopulmonary dysplasia in mice by promoting ETS1 expression.
    Yang M, Chen Y, Huang X, Shen F, Meng Y.

    02/21/2024
    Ets1 and IL17RA cooperate to regulate autoimmune responses and skin immunity to Staphylococcus aureus.

    Ets1 and IL17RA cooperate to regulate autoimmune responses and skin immunity to Staphylococcus aureus.
    Battaglia M, Sunshine AC, Luo W, Jin R, Stith A, Lindemann M, Miller LS, Sinha S, Wohlfert E, Garrett-Sinha LA., Free PMC Article

    09/28/2023
    ETS1 Ameliorates Hyperoxia-Induced Bronchopulmonary Dysplasia in Mice by Activating Nrf2/HO-1 Mediated Ferroptosis.

    ETS1 Ameliorates Hyperoxia-Induced Bronchopulmonary Dysplasia in Mice by Activating Nrf2/HO-1 Mediated Ferroptosis.
    Yang M, Chen Y, Huang X, Shen F, Meng Y., Free PMC Article

    08/30/2023
    Transcription factor ETS proto-oncogene 1 contributes to neuropathic pain by regulating histone deacetylase 1 in primary afferent neurons.

    Transcription factor ETS proto-oncogene 1 contributes to neuropathic pain by regulating histone deacetylase 1 in primary afferent neurons.
    Zheng HL, Sun SY, Jin T, Zhang M, Zeng Y, Liu Q, Yang K, Wei R, Pan Z, Lin F., Free PMC Article

    02/12/2023
    ETS1 loss in mice impairs cardiac outflow tract septation via a cell migration defect autonomous to the neural crest.

    ETS1 loss in mice impairs cardiac outflow tract septation via a cell migration defect autonomous to the neural crest.
    Lin L, Pinto A, Wang L, Fukatsu K, Yin Y, Bamforth SD, Bronner ME, Evans SM, Nie S, Anderson RH, Terskikh AV, Grossfeld PD., Free PMC Article

    12/24/2022
    B Cell Activation Results in IKK-Dependent, but Not c-Rel- or RelA-Dependent, Decreases in Transcription of the B Cell Tolerance-Inducing Gene Ets1.

    B Cell Activation Results in IKK-Dependent, but Not c-Rel- or RelA-Dependent, Decreases in Transcription of the B Cell Tolerance-Inducing Gene Ets1.
    Kearly A, Ottens K, Battaglia MC, Satterthwaite AB, Garrett-Sinha LA., Free PMC Article

    12/3/2022
    GATA4 Regulates Developing Endocardium Through Interaction With ETS1.

    GATA4 Regulates Developing Endocardium Through Interaction With ETS1.
    Zhou P, Zhang Y, Sethi I, Ye L, Trembley MA, Cao Y, Akerberg BN, Xiao F, Zhang X, Li K, Jardin BD, Mazumdar N, Ma Q, He A, Zhou B, Pu WT., Free PMC Article

    11/19/2022
    Endothelial Loss of ETS1 Impairs Coronary Vascular Development and Leads to Ventricular Non-Compaction.

    Endothelial Loss of ETS1 Impairs Coronary Vascular Development and Leads to Ventricular Non-Compaction.
    Wang L, Lin L, Qi H, Chen J, Grossfeld P., Free PMC Article

    08/27/2022
    Ets1 Promotes the Differentiation of Post-Selected iNKT Cells through Regulation of the Expression of Valpha14Jalpha18 T Cell Receptor and PLZF.

    Ets1 Promotes the Differentiation of Post-Selected iNKT Cells through Regulation of the Expression of Vα14Jα18 T Cell Receptor and PLZF.
    Chuang YT, Chuang WC, Liu CC, Liu CW, Huang YW, Yang HY, Ho IC, Tai TS., Free PMC Article

    12/18/2021
    Ets1 regulates the differentiation and function of iNKT cells through both Pointed domain-dependent and domain-independent mechanisms.

    Ets1 regulates the differentiation and function of iNKT cells through both Pointed domain-dependent and domain-independent mechanisms.
    Tai TS, Tsao HW, Chuang WC, Liu CC, Huang YW, Oettgen P, Chuang YT, Ho IC., Free PMC Article

    10/2/2021
    Gut commensals suppress interleukin-2 production through microRNA-200/BCL11B and microRNA-200/ETS-1 axes in lamina propria leukocytes of murine large intestine.

    Gut commensals suppress interleukin-2 production through microRNA-200/BCL11B and microRNA-200/ETS-1 axes in lamina propria leukocytes of murine large intestine.
    Ohsaka F, Karatsu Y, Kadota Y, Tochio T, Takemura N, Sonoyama K.

    04/17/2021
    Expression of ETS1 in gastric epithelial cells positively regulate inflammatory response in Helicobacter pylori-associated gastritis.

    Expression of ETS1 in gastric epithelial cells positively regulate inflammatory response in Helicobacter pylori-associated gastritis.
    Teng Y, Cang B, Mao F, Chen W, Cheng P, Peng L, Luo P, Lu D, You N, Zou Q, Zhuang Y., Free PMC Article

    03/27/2021
    miR-532-3p inhibits osteogenic differentiation in MC3T3-E1 cells by downregulating ETS1.

    miR-532-3p inhibits osteogenic differentiation in MC3T3-E1 cells by downregulating ETS1.
    Fan Q, Li Y, Sun Q, Jia Y, He C, Sun T.

    11/21/2020
    Batf Pioneers the Reorganization of Chromatin in Developing Effector T Cells via Ets1-Dependent Recruitment of Ctcf.

    Batf Pioneers the Reorganization of Chromatin in Developing Effector T Cells via Ets1-Dependent Recruitment of Ctcf.
    Pham D, Moseley CE, Gao M, Savic D, Winstead CJ, Sun M, Kee BL, Myers RM, Weaver CT, Hatton RD., Free PMC Article

    09/26/2020
    Ets-1 has an adverse impact on hepatocyte survival under TGF-beta1 treatment and accelerates the development of nonalcoholic steatohepatitis in mice.

    Ets-1 deficiency alleviates nonalcoholic steatohepatitis via weakening TGF-β1 signaling-mediated hepatocyte apoptosis.
    Liu D, Wang K, Li K, Xu R, Chang X, Zhu Y, Sun P, Han X., Free PMC Article

    07/18/2020
    Ets1 in restricting pathogenic Th cell responses and suggest a potential therapeutic target for atopic dermatitis treatment.

    Ets1 suppresses atopic dermatitis by suppressing pathogenic T cell responses.
    Lee CG, Kwon HK, Kang H, Kim Y, Nam JH, Won YH, Park S, Kim T, Kang K, Rudra D, Jun CD, Park ZY, Im SH., Free PMC Article

    06/6/2020
    Compressive force upregulated the expression of Ets-1 and Tks5.

    Orthodontic compressive force modulates Ets-1/Tks5 pathway to promote the formation of circumferential invadopodia and the fusion of osteoclast precursors.
    Wang Y, Zeng Z, Cheng Y, Zhao L, Yan Q, Qiu Y, Hu J, Guo J.

    05/16/2020
    Ets1 suppresses hepatic gluconeogenesis through modulating FoxO1 activity.

    Ets1-Mediated Acetylation of FoxO1 Is Critical for Gluconeogenesis Regulation during Feed-Fast Cycles.
    Li K, Qiu C, Sun P, Liu DC, Wu TJ, Wang K, Zhou YC, Chang XA, Yin Y, Chen F, Zhu YX, Han X.

    04/18/2020
    ETS-1 regulates endothelial-tomesenchymal transition in the murine heart

    Endothelial-specific deletion of Ets-1 attenuates Angiotensin II-induced cardiac fibrosis via suppression of endothelial-to-mesenchymal transition.
    Xu L, Fu M, Chen D, Han W, Ostrowski MC, Grossfeld P, Gao P, Ye M., Free PMC Article

    03/14/2020
    These results demonstrate that Ets1 is required in B cells to prevent autoimmune responses but that loss of Ets1 activity in other cell types is required for maximal autoimmune phenotypes.

    Ets1 Controls the Development of B Cell Autoimmune Responses in a Cell-Intrinsic Manner.
    Sunshine A, Goich D, Stith A, Sortino K, Dalton J, Metcalfe S, Svensson EC, Garrett-Sinha LA., Free PMC Article

    02/29/2020
    gene-targeted deletion of Ets-1 in mice results in some of the most common congenital kidney defects occurring in Jacobsen syndrome, including: duplicated kidney, hypoplastic kidney, and dilated renal pelvis and calyces... our results implicate Ets-1 in normal mammalian kidney development and, potentially, in the pathogenesis of some of the most common types of human structural kidney defects

    Gene-targeted deletion in mice of the Ets-1 transcription factor, a candidate gene in the Jacobsen syndrome kidney "critical region," causes abnormal kidney development.
    Ye M, Xu L, Fu M, Chen D, Mattina T, Zufardi O, Rossi E, Bush KT, Nigam SK, Grossfeld P.

    02/15/2020
    High ETS1 expression is associated with leukemic transformation.

    Ets1 Plays a Critical Role in MLL/EB1-Mediated Leukemic Transformation in a Mouse Bone Marrow Transplantation Model.
    Fu JF, Yen TH, Huang YJ, Shih LY., Free PMC Article

    11/30/2019
    Ets-1 transcription factor (Ets1) deletion in T cells induces systemic lupus erythematosus (SLE)-like autoimmunity in mice.

    The Transcription Factor Ets1 Suppresses T Follicular Helper Type 2 Cell Differentiation to Halt the Onset of Systemic Lupus Erythematosus.
    Kim CJ, Lee CG, Jung JY, Ghosh A, Hasan SN, Hwang SM, Kang H, Lee C, Kim GC, Rudra D, Suh CH, Im SH.

    06/1/2019
    Findings support the notion of a targeting mechanism for the selective diversification of antibody genes with limited genome wide mutagenesis by recruitment of Activation-induced cytidine deaminase by PAX5 and ETS1 in a transcription factor complex.

    ETS1 and PAX5 transcription factors recruit AID to Igh DNA.
    Grundström C, Kumar A, Priya A, Negi N, Grundström T.

    04/6/2019
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