| TFIP11 promotes replication fork reversal to preserve genome stability. | TFIP11 promotes replication fork reversal to preserve genome stability.
Chen J, Wu M, Yang Y, Ruan C, Luo Y, Song L, Wu T, Huang J, Yang B, Liu T., Free PMC Article | 02/16/2024 |
| DHX15-independent roles for TFIP11 in U6 snRNA modification, U4/U6.U5 tri-snRNP assembly and pre-mRNA splicing fidelity. | DHX15-independent roles for TFIP11 in U6 snRNA modification, U4/U6.U5 tri-snRNP assembly and pre-mRNA splicing fidelity.
Duchemin A, O'Grady T, Hanache S, Mereau A, Thiry M, Wacheul L, Michaux C, Perpète E, Hervouet E, Peixoto P, Ernst FGM, Audic Y, Dequiedt F, Lafontaine DLJ, Mottet D., Free PMC Article | 12/18/2021 |
| the high expression and activation effect on the ERK1/2 signaling of STIP in lymphoblastic leukemia suggest that STIP would be a potential therapy target or diagnosis marker for leukemia. | STIP Regulates ERK1/2 Signaling Pathway Involved in Interaction with PP1γ in Lymphoblastic Leukemia.
Sun S, Wang Y, Chen H, Fang L, Cui Y, Han X, Wu D, Li H, Ye M, Zhao X, Liu J. | 10/7/2017 |
| We now report the identification of a novel molecular function of STIP that links USP7 to the p53-Mdm2 pathway | STIP is a critical nuclear scaffolding protein linking USP7 to p53-Mdm2 pathway regulation.
Ye M, Tang Y, Tang S, Liu J, Wu K, Yao S, Sun Y, Zhou L, Deng T, Chen Y, Huang C, Tan W., Free PMC Article | 12/23/2016 |
| Results suggest that Sip1/tuftelin-interacting protein (STIP, also referred to as TFIP11) may be a novel potential diagnostic and therapeutic target for non-small cell lung cancer (NSCLC). | STIP overexpression confers oncogenic potential to human non-small cell lung cancer cells by regulating cell cycle and apoptosis.
Tang Y, Yan G, Song X, Wu K, Li Z, Yang C, Deng T, Sun Y, Hu X, Yang C, Bai H, Li H, Tan W, Ye M, Liu J., Free PMC Article | 12/17/2016 |
| the statistically significant association of rs2337359 upstream of TUFT1 with dental caries experience via meta-analysis across adult samples (p < 0.002) and the suggestive association for multiple variants in TFIP11 across child samples | Effects of enamel matrix genes on dental caries are moderated by fluoride exposures.
Shaffer JR, Carlson JC, Stanley BO, Feingold E, Cooper M, Vanyukov MM, Maher BS, Slayton RL, Willing MC, Reis SE, McNeil DW, Crout RJ, Weyant RJ, Levy SM, Vieira AR, Marazita ML., Free PMC Article | 04/18/2015 |
| Associations between TFIP11 (p=0.02), ENAM (p=0.00001), and AMELX (p=0.01) could be seen with caries independent of having MIH or genomic DNA copies of Streptococcus mutans detected by real time PCR in the Brazilian sample. | Genes expressed in dental enamel development are associated with molar-incisor hypomineralization.
Jeremias F, Koruyucu M, Küchler EC, Bayram M, Tuna EB, Deeley K, Pierri RA, Souza JF, Fragelli CM, Paschoal MA, Gencay K, Seymen F, Caminaga RM, dos Santos-Pinto L, Vieira AR., Free PMC Article | 04/26/2014 |
| These data help define the mechanism of nuclear/nuclear speckle localization of the splicing factor TFIP11, with implications for it's function. | Identification of a novel nuclear localization signal and speckle-targeting sequence of tuftelin-interacting protein 11, a splicing factor involved in spliceosome disassembly.
Tannukit S, Crabb TL, Hertel KJ, Wen X, Jans DA, Paine ML., Free PMC Article | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesComprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients.
Saus E, Brunet A, Armengol L, Alonso P, Crespo JM, Fernández-Aranda F, Guitart M, Martín-Santos R, Menchón JM, Navinés R, Soria V, Torrens M, Urretavizcaya M, Vallès V, Gratacòs M, Estivill X. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.
Gratacòs M, Costas J, de Cid R, Bayés M, González JR, Baca-García E, de Diego Y, Fernández-Aranda F, Fernández-Piqueras J, Guitart M, Martín-Santos R, Martorell L, Menchón JM, Roca M, Sáiz-Ruiz J, Sanjuán J, Torrens M, Urretavizcaya M, Valero J, Vilella E, Estivill X, Carracedo A, Psychiatric Genetics Network Group. | 01/11/2009 |
| Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) | Enamel formation genes are associated with high caries experience in Turkish children.
Patir A, Seymen F, Yildirim M, Deeley K, Cooper ME, Marazita ML, Vieira AR., Free PMC Article | 09/24/2008 |
| TFIP11 is a novel splicing factor and transfected TFIP11-GFP fusion protein was found to locate in a novel subnuclear TFIP body. | Structural organization and cellular localization of tuftelin-interacting protein 11 (TFIP11).
Wen X, Lei YP, Zhou YL, Okamoto CT, Snead ML, Paine ML. | 01/21/2010 |