| Identifying ALOX15-initiated lipid peroxidation increases susceptibility to ferroptosis in asthma epithelial cells. | Identifying ALOX15-initiated lipid peroxidation increases susceptibility to ferroptosis in asthma epithelial cells.
Zhang W, Huang F, Ding X, Qin J, Wang W, Luo L. | 05/29/2024 |
| Association between arachidonate lipoxygenase 15,c.-292 C > T gene polymorphism and non-cystic fibrosis bronchiectasis in children: a pilot study on the effects on airway lipoxin A4 and disease phenotype. | Association between arachidonate lipoxygenase 15,c.-292 C > T gene polymorphism and non-cystic fibrosis bronchiectasis in children: a pilot study on the effects on airway lipoxin A4 and disease phenotype.
Hussein MM, Fouda EM, Shehab Y, Nabih ES, Osman AM, Ishak SR., Free PMC Article | 05/1/2024 |
| Epigenetic regulation of 15-lipoxygenase-1 expression in human chondrocytes by promoter methylation. | Epigenetic regulation of 15-lipoxygenase-1 expression in human chondrocytes by promoter methylation.
Alsabri SG, Guedi GG, Najar M, Merimi M, Lavoie F, Grabs D, Fernandes J, Pelletier JP, Martel-Pelletier J, Benderdour M, Fahmi H. | 11/29/2023 |
| A review on the relationship between Arachidonic acid 15-Lipoxygenase (ALOX15) and diabetes mellitus. | A review on the relationship between Arachidonic acid 15-Lipoxygenase (ALOX15) and diabetes mellitus.
He K, Zhou X, Du H, Zhao J, Deng R, Wang J., Free PMC Article | 10/30/2023 |
| 15-lipoxygenase and cyclooxygenase expression profile and their related modulators in COVID-19 infection. | 15-lipoxygenase and cyclooxygenase expression profile and their related modulators in COVID-19 infection.
Kianfar S, Salimi V, Jahangirifard A, Mirtajani SB, Vaezi MA, Yavarian J, Mokhtari-Azad T, Tavakoli-Yaraki M. | 10/11/2023 |
| CircRNA 06209 inhibits cataract development by sponging miR-6848-5p and regulating ALOX15 expression. | CircRNA 06209 inhibits cataract development by sponging miR-6848-5p and regulating ALOX15 expression.
Fang R, Li JH, Li HL, Yue PL, Ding XF, Jia YX, Liu ZC, Zhou HG, Yang C, Song XD. | 10/2/2023 |
| Photothermal lipolysis accelerates ECM production via macrophage-derived ALOX15-mediated p38 MAPK activation in fibroblasts. | Photothermal lipolysis accelerates ECM production via macrophage-derived ALOX15-mediated p38 MAPK activation in fibroblasts.
Wu S, Wang C, Yao M, Han D, Li Q. | 04/6/2023 |
| Poly(rC)-binding protein 1 represses ferritinophagy-mediated ferroptosis in head and neck cancer. | Poly(rC)-binding protein 1 represses ferritinophagy-mediated ferroptosis in head and neck cancer.
Lee J, You JH, Roh JL., Free PMC Article | 04/23/2022 |
| 15LO1 dictates glutathione redox changes in asthmatic airway epithelium to worsen type 2 inflammation. | 15LO1 dictates glutathione redox changes in asthmatic airway epithelium to worsen type 2 inflammation.
Nagasaki T, Schuyler AJ, Zhao J, Samovich SN, Yamada K, Deng Y, Ginebaugh SP, Christenson SA, Woodruff PG, Fahy JV, Trudeau JB, Stoyanovsky D, Ray A, Tyurina YY, Kagan VE, Wenzel SE., Free PMC Article | 02/19/2022 |
| Characterization of Mice Ubiquitously Overexpressing Human 15-Lipoxygenase-1: Effect of Diabetes on Peripheral Neuropathy and Treatment with Menhaden Oil. | Characterization of Mice Ubiquitously Overexpressing Human 15-Lipoxygenase-1: Effect of Diabetes on Peripheral Neuropathy and Treatment with Menhaden Oil.
Coppey L, Obrosov A, Shevalye H, Davidson E, Paradee W, Yorek MA., Free PMC Article | 11/27/2021 |
| 12/15-Lipoxygenase choreographs the resolution of IgG-mediated skin inflammation. | 12/15-Lipoxygenase choreographs the resolution of IgG-mediated skin inflammation.
Sezin T, Ferreirós N, Jennrich M, Ochirbold K, Seutter M, Attah C, Mousavi S, Zillikens D, Geisslinger G, Sadik CD. | 10/16/2021 |
| Enhanced 15-Lipoxygenase 1 Production is Related to Periostin Expression and Eosinophil Recruitment in Eosinophilic Chronic Rhinosinusitis. | Enhanced 15-Lipoxygenase 1 Production is Related to Periostin Expression and Eosinophil Recruitment in Eosinophilic Chronic Rhinosinusitis.
Imoto Y, Takabayashi T, Sakashita M, Kato Y, Yoshida K, Kidoguchi M, Koyama K, Adachi N, Kimura Y, Ogi K, Ito Y, Kanno M, Okamoto M, Narita N, Fujieda S., Free PMC Article | 09/11/2021 |
| Association between ALOX15 gene polymorphism and brick-tea type skeletal fluorosis in Tibetans, Kazaks and Han, China. | Association between ALOX15 gene polymorphism and brick-tea type skeletal fluorosis in Tibetans, Kazaks and Han, China.
Chu Y, Liu Y, Guo N, Lou Q, Wang L, Huang W, Wu L, Wang J, Zhang M, Yin F, Gao Y, Yang Y. | 07/24/2021 |
| The Emerging Role of COX-2, 15-LOX and PPARgamma in Metabolic Diseases and Cancer: An Introduction to Novel Multi-target Directed Ligands (MTDLs). | The Emerging Role of COX-2, 15-LOX and PPARγ in Metabolic Diseases and Cancer: An Introduction to Novel Multi-target Directed Ligands (MTDLs).
Alaaeddine RA, Elzahhar PA, AlZaim I, Abou-Kheir W, Belal ASF, El-Yazbi AF. | 05/29/2021 |
| Biosynthesis of the Maresin Intermediate, 13S,14S-Epoxy-DHA, by Human 15-Lipoxygenase and 12-Lipoxygenase and Its Regulation through Negative Allosteric Modulators. | Biosynthesis of the Maresin Intermediate, 13S,14S-Epoxy-DHA, by Human 15-Lipoxygenase and 12-Lipoxygenase and Its Regulation through Negative Allosteric Modulators.
Freedman C, Tran A, Tourdot BE, Kalyanaraman C, Perry S, Holinstat M, Jacobson MP, Holman TR., Free PMC Article | 01/23/2021 |
| A role of Gln596 in fine-tuning mammalian ALOX15 specificity, protein stability and allosteric properties. | A role of Gln596 in fine-tuning mammalian ALOX15 specificity, protein stability and allosteric properties.
Cruz A, Di Venere A, Mei G, Zhuravlev A, Golovanov A, Stehling S, Heydeck D, Lluch JM, González-Lafont À, Kuhn H, Ivanov I. | 10/24/2020 |
| Stereochemical analysis revealed that Trihydroxyoctadecenoic acids produced by eosinophils predominantly evidenced the 13(S) configuration, suggesting 15-lipoxygenase (15-LOX)-mediated synthesis. | Eosinophils synthesize trihydroxyoctadecenoic acids (TriHOMEs) via a 15-lipoxygenase dependent process.
Fuchs D, Tang X, Johnsson AK, Dahlén SE, Hamberg M, Wheelock CE. | 07/18/2020 |
| High ALOX15 expression is associated with Rett syndrome OxInflammation. | 13-HODE, 9-HODE and ALOX15 as potential players in Rett syndrome OxInflammation.
Pecorelli A, Cervellati C, Cordone V, Amicarelli F, Hayek J, Valacchi G. | 04/25/2020 |
| Low 15-LOX-1 expression is associated with lung carcinogenesis. | Ambient fine particulate matter inhibits 15-lipoxygenases to promote lung carcinogenesis.
Li MY, Liu LZ, Li W, Ng CSH, Liu Y, Kong AWY, Zhao Z, Wang S, Qi H, Jia H, Yang S, Du J, Long X, Ho RLK, Chak ECW, Wan IYP, Mok TSK, Underwood MJ, Gali NK, Ning Z, Chen GG., Free PMC Article | 02/15/2020 |
| ALOX15 expression and up-regulation in the functional and non-functional pituitary adenomas. | Up-regulation of 15-lipoxygenase enzymes and products in functional and non-functional pituitary adenomas.
Barooni AB, Ghorbani M, Salimi V, Alimohammadi A, Khamseh ME, Akbari H, Imani M, Nourbakhsh M, Sheikhi A, Shirian FI, Ameri M, Tavakoli-Yaraki M., Free PMC Article | 01/4/2020 |
| The activity of 15-Lipoxygenase expression levels were increased in patients with multiple sclerosis compared to healthy controls. | The role of expression and activity of 15-Lipoxygenase isoforms and related cytokines in patients with Multiple Sclerosis and healthy controls.
Safizadeh B, Hoshyar R, Mehrpour M, Eftekhar M, Salimi V, Yazdani S, Bijari B, Khodakhah F, Tavakoli-Yaraki M. | 10/5/2019 |
| 5-LOX does not react with 5,15-diHpETE, although it can produce lipoxin A4 when 15-HpETE is the substrate. In contrast, both 12-LOX and 15-LOX-1 react with 5,15-diHpETE, forming specifically lipoxin B4. | 5 S,15 S-Dihydroperoxyeicosatetraenoic Acid (5,15-diHpETE) as a Lipoxin Intermediate: Reactivity and Kinetics with Human Leukocyte 5-Lipoxygenase, Platelet 12-Lipoxygenase, and Reticulocyte 15-Lipoxygenase-1.
Green AR, Freedman C, Tena J, Tourdot BE, Liu B, Holinstat M, Holman TR., Free PMC Article | 08/3/2019 |
| ALOX15 expression was positive in pauci-eosinophilic biopsies from children with eosinophilic esophagitis and negative in healthy controls. | ALOX15 Immunohistochemistry Aids in the Diagnosis of Eosinophilic Esophagitis on Pauci-eosinophilic Biopsies in Children.
Hui Y, Chen S, Lombardo KA, Resnick MB, Mangray S, Matoso A. | 05/25/2019 |
| This review summarizes our current knowledge on the role of 12/15-LOX in inflammation and various human diseases. [Review] | Emerging role of 12/15-Lipoxygenase (ALOX15) in human pathologies.
Singh NK, Rao GN., Free PMC Article | 05/11/2019 |
| MAO-A expression is co-induced with 15-lipoxygenase (15-LO) in interleukin 13 (IL-13)-activated primary human monocytes and A549 non-small cell lung carcinoma cells. | Regulation of monoamine oxidase A (MAO-A) expression, activity, and function in IL-13-stimulated monocytes and A549 lung carcinoma cells.
Dhabal S, Das P, Biswas P, Kumari P, Yakubenko VP, Kundu S, Cathcart MK, Kundu M, Biswas K, Bhattacharjee A., Free PMC Article | 03/2/2019 |