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    FUS FUS RNA binding protein [ Homo sapiens (human) ]

    Gene ID: 2521, updated on 8-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    FUS-Mediated CircFGFR1 Accelerates the Development of Papillary Thyroid Carcinoma by Stabilizing FGFR1 Protein.

    FUS-Mediated CircFGFR1 Accelerates the Development of Papillary Thyroid Carcinoma by Stabilizing FGFR1 Protein.
    Zheng L, Tang T, Wang Z, Sun C, Chen X, Li W, Wang B.

    10/2/2024
    Frontotemporal dementia-like disease progression elicited by seeded aggregation and spread of FUS.

    Frontotemporal dementia-like disease progression elicited by seeded aggregation and spread of FUS.
    Vazquez-Sanchez S, Tilkin B, Gasset-Rosa F, Zhang S, Piol D, McAlonis-Downes M, Artates J, Govea-Perez N, Verresen Y, Guo L, Cleveland DW, Shorter J, Da Cruz S., Free PMC Article

    06/25/2024
    Post-translational modification sites are present in hydrophilic cavities of alpha-synuclein, tau, FUS, and TDP-43 fibrils: A molecular dynamics study.

    Post-translational modification sites are present in hydrophilic cavities of alpha-synuclein, tau, FUS, and TDP-43 fibrils: A molecular dynamics study.
    Kochen NN, Seaney D, Vasandani V, Murray M, Braun AR, Sachs JN.,

    06/14/2024
    FUS reads histone H3K36me3 to regulate alternative polyadenylation.

    FUS reads histone H3K36me3 to regulate alternative polyadenylation.
    Jia J, Fan H, Wan X, Fang Y, Li Z, Tang Y, Zhang Y, Huang J, Fang D., Free PMC Article

    06/11/2024
    Deciphering the role of FUS::DDIT3 expression and tumor microenvironment in myxoid liposarcoma development.

    Deciphering the role of FUS::DDIT3 expression and tumor microenvironment in myxoid liposarcoma development.
    Ranji P, Jonasson E, Andersson L, Filges S, Luna Santamaría M, Vannas C, Dolatabadi S, Gustafsson A, Myklebost O, Håkansson J, Fagman H, Landberg G, Åman P, Ståhlberg A., Free PMC Article

    05/23/2024
    A dynamic regulatory switch for phase separation of FUS protein: Zinc ions and zinc finger domain.

    A dynamic regulatory switch for phase separation of FUS protein: Zinc ions and zinc finger domain.
    Chen Y, Pei X, Chen L, Chen L.

    05/2/2024
    An aberrant fused in sarcoma liquid droplet of amyotrophic lateral sclerosis pathological variant, R495X, accelerates liquid-solid phase transition.

    An aberrant fused in sarcoma liquid droplet of amyotrophic lateral sclerosis pathological variant, R495X, accelerates liquid-solid phase transition.
    Shiramasa Y, Yamamoto R, Kashiwagi N, Sasaki F, Imai S, Ike M, Kitazawa S, Kameda T, Kitahara R., Free PMC Article

    05/2/2024
    RNA and the RNA-binding protein FUS act in concert to prevent TDP-43 spatial segregation.

    RNA and the RNA-binding protein FUS act in concert to prevent TDP-43 spatial segregation.
    Demongin C, Tranier S, Joshi V, Ceschi L, Desforges B, Pastré D, Hamon L., Free PMC Article

    04/16/2024
    Cell-Type-Dependent Recruitment Dynamics of FUS Protein at Laser-Induced DNA Damage Sites.

    Cell-Type-Dependent Recruitment Dynamics of FUS Protein at Laser-Induced DNA Damage Sites.
    Niu Y, Pal A, Szewczyk B, Japtok J, Naumann M, Glaß H, Hermann A., Free PMC Article

    04/2/2024
    FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease.

    FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease.
    Kodavati M, Wang H, Guo W, Mitra J, Hegde PM, Provasek V, Rao VHM, Vedula I, Zhang A, Mitra S, Tomkinson AE, Hamilton DJ, Van Den Bosch L, Hegde ML., Free PMC Article

    03/28/2024
    LncRNA ABHD11-AS1 activates EGFR signaling to promote cervical cancer progression by preventing FUS-mediated degradation of ABHD11 mRNA.

    LncRNA ABHD11-AS1 activates EGFR signaling to promote cervical cancer progression by preventing FUS-mediated degradation of ABHD11 mRNA.
    Yang T, Tian S, Zhao J, Pei M, Zhao M, Yang X., Free PMC Article

    03/8/2024
    Binding of the nuclear ribonucleoprotein family member FUS to RNA prevents R-loop RNA:DNA hybrid structures.

    Binding of the nuclear ribonucleoprotein family member FUS to RNA prevents R-loop RNA:DNA hybrid structures.
    Thompson VF, Wieland DR, Mendoza-Leon V, Janis HI, Lay MA, Harrell LM, Schwartz JC., Free PMC Article

    03/4/2024
    Circular RNA CircSATB2 facilitates osteosarcoma progression through regulating the miR-661/FUS-mediated mRNA of ZNFX1.

    Circular RNA CircSATB2 facilitates osteosarcoma progression through regulating the miR-661/FUS-mediated mRNA of ZNFX1.
    Wang Z, She D, Liu L, Hua X, Zhu H, Yu L, Wang H, Zhu Y, Fan G, Wang Y, Xu M, Zhou G.

    01/16/2024
    Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs.

    Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs.
    Zhu Y, Burg T, Neyrinck K, Vervliet T, Nami F, Vervoort E, Ahuja K, Sassano ML, Chai YC, Tharkeshwar AK, De Smedt J, Hu H, Bultynck G, Agostinis P, Swinnen JV, Van Den Bosch L, da Costa RFM, Verfaillie C., Free PMC Article

    01/9/2024
    Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions.

    Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions.
    Schöpf J, Uhrig S, Heilig CE, Lee KS, Walther T, Carazzato A, Dobberkau AM, Weichenhan D, Plass C, Hartmann M, Diwan GD, Carrero ZI, Ball CR, Hohl T, Kindler T, Rudolph-Hähnel P, Helm D, Schneider M, Nilsson A, Øra I, Imle R, Banito A, Russell RB, Jones BC, Lipka DB, Glimm H, Hübschmann D, Hartmann W, Fröhling S, Scholl C., Free PMC Article

    01/9/2024
    "Boundary residues" between the folded RNA recognition motif and disordered RGG domains are critical for FUS-RNA binding.

    "Boundary residues" between the folded RNA recognition motif and disordered RGG domains are critical for FUS-RNA binding.
    Balasubramanian S, Maharana S, Srivastava A., Free PMC Article

    01/9/2024
    FUS regulates the alternative splicing of cell proliferation genes related to atherosclerosis.

    FUS regulates the alternative splicing of cell proliferation genes related to atherosclerosis.
    Hou J, Yang S, Guo Y, Yan N, Jia S., Free PMC Article

    12/15/2023
    FUS RRM regulates poly(ADP-ribose) levels after transcriptional arrest and PARP-1 activation on DNA damage.

    FUS RRM regulates poly(ADP-ribose) levels after transcriptional arrest and PARP-1 activation on DNA damage.
    Mamontova EM, Clément MJ, Sukhanova MV, Joshi V, Bouhss A, Rengifo-Gonzalez JC, Desforges B, Hamon L, Lavrik OI, Pastré D.

    12/5/2023
    Nucleocapsid proteins from human coronaviruses possess phase separation capabilities and promote FUS pathological aggregation.

    Nucleocapsid proteins from human coronaviruses possess phase separation capabilities and promote FUS pathological aggregation.
    Dong H, Zhang H, Jalin J, He Z, Wang R, Huang L, Liu Z, Zhang S, Dai B, Li D.,

    11/30/2023
    LINC01133 can induce acquired ferroptosis resistance by enhancing the FSP1 mRNA stability through forming the LINC01133-FUS-FSP1 complex.

    LINC01133 can induce acquired ferroptosis resistance by enhancing the FSP1 mRNA stability through forming the LINC01133-FUS-FSP1 complex.
    Wang S, Chen J, Li P, Chen Y., Free PMC Article

    11/29/2023
    Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-kappaB inhibition.

    Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-κB inhibition.
    Pelaez MC, Desmeules A, Gelon PA, Glasson B, Marcadet L, Rodgers A, Phaneuf D, Pozzi S, Dutchak PA, Julien JP, Sephton CF., Free PMC Article

    11/21/2023
    lncRNA Sequencing Reveals Neurodegeneration-Associated FUS Mutations Alter Transcriptional Landscape of iPS Cells That Persists in Motor Neurons.

    lncRNA Sequencing Reveals Neurodegeneration-Associated FUS Mutations Alter Transcriptional Landscape of iPS Cells That Persists in Motor Neurons.
    Provasek VE, Kodavati M, Guo W, Wang H, Boldogh I, Van Den Bosch L, Britz G, Hegde ML., Free PMC Article

    11/16/2023
    Abl kinase-mediated FUS Tyr526 phosphorylation alters nucleocytoplasmic FUS localization in FTLD-FUS.

    Abl kinase-mediated FUS Tyr526 phosphorylation alters nucleocytoplasmic FUS localization in FTLD-FUS.
    Motaln H, Čerček U, Yamoah A, Tripathi P, Aronica E, Goswami A, Rogelj B., Free PMC Article

    10/10/2023
    The lncRNA HOTAIR attenuates pyroptosis of diabetic cardiomyocytes by recruiting FUS to regulate SIRT3 expression.

    The lncRNA HOTAIR attenuates pyroptosis of diabetic cardiomyocytes by recruiting FUS to regulate SIRT3 expression.
    Xiong J, Zhou Q.

    08/25/2023
    FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD.

    FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD.
    Fujino Y, Ueyama M, Ishiguro T, Ozawa D, Ito H, Sugiki T, Murata A, Ishiguro A, Gendron T, Mori K, Tokuda E, Taminato T, Konno T, Koyama A, Kawabe Y, Takeuchi T, Furukawa Y, Fujiwara T, Ikeda M, Mizuno T, Mochizuki H, Mizusawa H, Wada K, Ishikawa K, Onodera O, Nakatani K, Petrucelli L, Taguchi H, Nagai Y., Free PMC Article

    07/25/2023
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