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    FUT2 fucosyltransferase 2 (H blood group) [ Homo sapiens (human) ]

    Gene ID: 2524, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    FUT2 promotes colorectal cancer metastasis by reprogramming fatty acid metabolism via YAP/TAZ signaling and SREBP-1.

    FUT2 promotes colorectal cancer metastasis by reprogramming fatty acid metabolism via YAP/TAZ signaling and SREBP-1.
    Dong C, Zhang Y, Zeng J, Chong S, Liu Y, Bian Z, Fan S, Chen X., Free PMC Article

    10/21/2024
    Chemo-sensory loss and FUT2 gene in COVID-19 infected Iraqi dentists.

    Chemo-sensory loss and FUT2 gene in COVID-19 infected Iraqi dentists.
    Abdulrida FM, Diajil AR.

    09/16/2024
    Altered gut microbiome in FUT2 loss-of-function mutants in support of personalized medicine for inflammatory bowel diseases.

    Altered gut microbiome in FUT2 loss-of-function mutants in support of personalized medicine for inflammatory bowel diseases.
    Cheng S, Hu J, Wu X, Pan JA, Jiao N, Li Y, Huang Y, Lin X, Zou Y, Chen Y, Zhu L, Zhi M, Lan P.

    07/29/2024
    Association between antibiotic use during early life and early-onset colorectal cancer risk overall and according to polygenic risk and FUT2 genotypes.

    Association between antibiotic use during early life and early-onset colorectal cancer risk overall and according to polygenic risk and FUT2 genotypes.
    Jiang F, Boakye D, Sun J, Wang L, Yu L, Zhou X, Zhao J, Bian Z, Song P, He Y, Zhu Y, Chen J, Yuan S, Song M, Larsson SC, Giovannucci EL, Theodoratou E, Ding K, Li X., Free PMC Article

    09/12/2023
    Relationship between ABO Blood Group Alleles and Pancreatic Cancer Is Modulated by Secretor (FUT2) Genotype, but Not Lewis Antigen (FUT3) Genotype.

    Relationship between ABO Blood Group Alleles and Pancreatic Cancer Is Modulated by Secretor (FUT2) Genotype, but Not Lewis Antigen (FUT3) Genotype.
    Kim J, Yuan C, Amundadottir LT, Wolpin BM, Pancreatic Cancer Cohort Consortium (PanScan), Klein AP, Pancreatic Cancer Case–Control Consortium (PanC4), Risch HA, Kraft P., Free PMC Article

    09/6/2023
    FUT2 promotes the tumorigenicity and metastasis of colorectal cancer cells via the Wnt/betacatenin pathway.

    FUT2 promotes the tumorigenicity and metastasis of colorectal cancer cells via the Wnt/β‑catenin pathway.
    Liu P, Liu J, Ding M, Liu Y, Zhang Y, Chen X, Zhou Z., Free PMC Article

    02/11/2023
    Audiologic Measures in an Indigenous Community with A2ML1- and FUT2-Related Otitis Media.

    Audiologic Measures in an Indigenous Community with A2ML1- and FUT2-Related Otitis Media.
    Santos-Cortez RLP, Ong KMC, Carlos-Hiceta A, Tantoco MLC, Yarza TKL, San Agustin ML, Pedro M, Cruz TLG, Cutiongco-de la Paz EM, Abes GT, Llanes EGDV, Chan AL, Chiong CM, Reyes-Quintos MRT., Free PMC Article

    02/11/2023
    Gut Microbiome Composition and Metabolic Capacity Differ by FUT2 Secretor Status in Exclusively Breastfed Infants.

    Gut Microbiome Composition and Metabolic Capacity Differ by FUT2 Secretor Status in Exclusively Breastfed Infants.
    Thorman AW, Adkins G, Conrey SC, Burrell AR, Yu Y, White B, Burke R, Haslam D, Payne DC, Staat MA, Morrow AL, Newburg DS., Free PMC Article

    01/28/2023
    FUT2 Facilitates Autophagy and Suppresses Apoptosis via p53 and JNK Signaling in Lung Adenocarcinoma Cells.

    FUT2 Facilitates Autophagy and Suppresses Apoptosis via p53 and JNK Signaling in Lung Adenocarcinoma Cells.
    Zhang Y, Yao E, Liu Y, Zhang Y, Ding M, Liu J, Chen X, Fan S., Free PMC Article

    01/11/2023
    Maternal and child FUT2 and FUT3 status demonstrate relationship with gut health, body composition and growth of children in Bangladesh.

    Maternal and child FUT2 and FUT3 status demonstrate relationship with gut health, body composition and growth of children in Bangladesh.
    Gazi MA, Fahim SM, Hasan MM, Hossaini F, Alam MA, Hossain MS, Hossain MD, Das S, Haque R, Mahfuz M, Ahmed T., Free PMC Article

    11/12/2022
    Effect of the variant rs602662 of FUT2 gene on anthropometric and metabolic parameters in a Caucasian obese population.

    Effect of the variant rs602662 of FUT2 gene on anthropometric and metabolic parameters in a Caucasian obese population.
    de Luis D, Izaola O, Primo D.

    10/29/2022
    The FUT2 Variant c.461G>A (p.Trp154*) Is Associated With Differentially Expressed Genes and Nasopharyngeal Microbiota Shifts in Patients With Otitis Media.

    The FUT2 Variant c.461G>A (p.Trp154*) Is Associated With Differentially Expressed Genes and Nasopharyngeal Microbiota Shifts in Patients With Otitis Media.
    Elling CL, Scholes MA, Streubel SO, Larson ED, Wine TM, Bootpetch TC, Yoon PJ, Kofonow JM, Gubbels SP, Cass SP, Robertson CE, Jenkins HA, Prager JD, Frank DN, Chan KH, Friedman NR, Ryan AF, Santos-Cortez RLP., Free PMC Article

    06/18/2022
    Two novel alleles on Fucosyltransferase 2 from northern Thai para-Bombay family and computational prediction on mutation effect.

    Two novel alleles on Fucosyltransferase 2 from northern Thai para-Bombay family and computational prediction on mutation effect.
    Anukul N, Wita R, Leetrakool N, Sirikul C, Veeraphan N, Wongchai S.

    04/23/2022
    A one-year study of human milk oligosaccharide profiles in the milk of healthy UK mothers and their relationship to maternal FUT2 genotype.

    A one-year study of human milk oligosaccharide profiles in the milk of healthy UK mothers and their relationship to maternal FUT2 genotype.
    Durham SD, Robinson RC, Olga L, Ong KK, Chichlowski M, Dunger DB, Barile D.

    03/26/2022
    Association of fucosyltransferase 2 gene with norovirus infection: A systematic review and meta-analysis.

    Association of fucosyltransferase 2 gene with norovirus infection: A systematic review and meta-analysis.
    Hong X, Xue L, Liao Y, Wu A, Jiang Y, Kou X.

    03/19/2022
    Fucosyltransferase 2 Mutations Are Associated With a Favorable Clinical Course in Crohn's Disease.

    Fucosyltransferase 2 Mutations Are Associated With a Favorable Clinical Course in Crohn's Disease.
    Battat R, Qatomah A, Kopylov U, Wyse J, Cohen A, Afif W, Lakatos PL, Seidman E, Bitton A, Bessissow T.

    03/12/2022
    Survey and characterization of nonfunctional alleles of FUT2 in a database.

    Survey and characterization of nonfunctional alleles of FUT2 in a database.
    Soejima M, Koda Y., Free PMC Article

    11/22/2021
    Rapid detection of phenotypes Bombay se(del) and nonsecretor rs200157007 SNP (302C > T) by real-time PCR-based methods.

    Rapid detection of phenotypes Bombay se(del) and nonsecretor rs200157007 SNP (302C > T) by real-time PCR-based methods.
    Soejima M, Koda Y., Free PMC Article

    11/13/2021
    Estimation of genetic variation in the Secretor and Lewis genes in Iranian hospitalized children.

    Estimation of genetic variation in the Secretor and Lewis genes in Iranian hospitalized children.
    Farahmand M, Jalilvand S, Arashkia A, Izadi A, Forouzannia SM, Mollaei-Kandelous Y, Shoja Z.

    10/30/2021
    Enhanced Protection Against Diarrhea Among Breastfed Infants of Nonsecretor Mothers.

    Enhanced Protection Against Diarrhea Among Breastfed Infants of Nonsecretor Mothers.
    Muthumuni D, Miliku K, Wade KH, Timpson NJ, Azad MB.

    09/25/2021
    Maternal Fucosyltransferase 2 Status Associates with the Profiles of Human Milk Oligosaccharides and the Fecal Microbiota Composition of Breastfed Infants.

    Maternal Fucosyltransferase 2 Status Associates with the Profiles of Human Milk Oligosaccharides and the Fecal Microbiota Composition of Breastfed Infants.
    Liu F, Yan J, Wang X, Wang C, Chen L, Li Y, Chen J, Guo H.

    06/26/2021
    The role of the blood group-related glycosyltransferases FUT2 and B4GALNT2 in susceptibility to infectious disease.

    The role of the blood group-related glycosyltransferases FUT2 and B4GALNT2 in susceptibility to infectious disease.
    Galeev A, Suwandi A, Cepic A, Basu M, Baines JF, Grassl GA.

    06/26/2021
    ""FUT2"" a potential genetic modifier in NCF1 deficiency.

    "FUT2" a potential genetic modifier in NCF1 deficiency.
    Bargir UA, Hule GP, Kambli P, Kulkarni M, Donta AK, Taur P, Gorakshakar A, Desai M, Madkaikar MR.

    06/12/2021
    Can the FUT 2 Gene Variant Have an Effect on the Body Weight of Patients Undergoing Bariatric Surgery?-Preliminary, Exploratory Study.

    Can the FUT 2 Gene Variant Have an Effect on the Body Weight of Patients Undergoing Bariatric Surgery?-Preliminary, Exploratory Study.
    Komorniak N, Martynova-Van Kley A, Nalian A, Wardziukiewicz W, Skonieczna-Żydecka K, Styburski D, Palma J, Kowalewski B, Kaseja K, Stachowska E., Free PMC Article

    04/3/2021
    Genetic Manipulation of Human Intestinal Enteroids Demonstrates the Necessity of a Functional Fucosyltransferase 2 Gene for Secretor-Dependent Human Norovirus Infection.

    Genetic Manipulation of Human Intestinal Enteroids Demonstrates the Necessity of a Functional Fucosyltransferase 2 Gene for Secretor-Dependent Human Norovirus Infection.
    Haga K, Ettayebi K, Tenge VR, Karandikar UC, Lewis MA, Lin SC, Neill FH, Ayyar BV, Zeng XL, Larson G, Ramani S, Atmar RL, Estes MK., Free PMC Article

    03/13/2021
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