| ACKR1 gene polymorphisms in Bombay blood group (Oh) individuals of Indian origin. | ACKR1 gene polymorphisms in Bombay blood group (O(h)) individuals of Indian origin.
Shaikh R, Kanjaksha G, Kashivishwanath V, Kulkarni S, Jadhav S, Maru H, Gorakshakar A. | 09/20/2024 |
| Allelic frequency variation of ACKR1 in three Algerian populations: Zenata, Reguibat, and Oran. | Allelic frequency variation of ACKR1 in three Algerian populations: Zenata, Reguibat, and Oran.
Adda Neggaz L, Deba T, Bekada A, Meroufel Sebaa DN, Mediene Benchekor S, Benhamamouch S. | 02/9/2024 |
| Clinical and immunological features in ACKR1/DARC-associated neutropenia. | Clinical and immunological features in ACKR1/DARC-associated neutropenia.
Palmblad J, Sohlberg E, Nilsson CC, Lindqvist H, Deneberg S, Ratcliffe P, Meinke S, Mörtberg A, Klimkowska M, Höglund P., Free PMC Article | 01/30/2024 |
| Single-cell Transcriptomic Analysis Reveals an Immunosuppressive Network Between POSTN CAFs and ACKR1 ECs in TKI-resistant Lung Cancer. | Single-cell Transcriptomic Analysis Reveals an Immunosuppressive Network Between POSTN CAFs and ACKR1 ECs in TKI-resistant Lung Cancer.
Wang Z, Yan N, Sheng H, Xiao Y, Sun J, Cao C., Free PMC Article | 01/5/2024 |
| Structural basis for DARC binding in reticulocyte invasion by Plasmodium vivax. | Structural basis for DARC binding in reticulocyte invasion by Plasmodium vivax.
Moskovitz R, Pholcharee T, DonVito SM, Guloglu B, Lowe E, Mohring F, Moon RW, Higgins MK., Free PMC Article | 06/23/2023 |
| Endothelial ACKR1 is induced by neutrophil contact and down-regulated by secretion in extracellular vesicles. | Endothelial ACKR1 is induced by neutrophil contact and down-regulated by secretion in extracellular vesicles.
Guo X, Khosraviani N, Raju S, Singh J, Farahani NZ, Abramian M, Torres VJ, Howe KL, Fish JE, Kapus A, Lee WL., Free PMC Article | 05/18/2023 |
| Presence of ""ACKR1/DARC null"" polymorphism in Arabs from Jisr az-Zarqa with benign ethnic neutropenia. | Presence of "ACKR1/DARC null" polymorphism in Arabs from Jisr az-Zarqa with benign ethnic neutropenia.
Elhadad D, Simon AJ, Bronstein Y, Yana M, Sharon N. | 07/30/2022 |
| Association Between a Common, Benign Genotype and Unnecessary Bone Marrow Biopsies Among African American Patients. | Association Between a Common, Benign Genotype and Unnecessary Bone Marrow Biopsies Among African American Patients.
Van Driest SL, Abul-Husn NS, Glessner JT, Bastarache L, Nirenberg S, Schildcrout JS, Eswarappa MS, Belbin GM, Shaffer CM, Mentch F, Connolly J, Shi M, Stein CM, Roden DM, Hakonarson H, Cox NJ, Borinstein SC, Mosley JD., Free PMC Article | 03/19/2022 |
| The dimeric form of CXCL12 binds to atypical chemokine receptor 1. | The dimeric form of CXCL12 binds to atypical chemokine receptor 1.
Gutjahr JC, Crawford KS, Jensen DR, Naik P, Peterson FC, Samson GPB, Legler DF, Duchene J, Veldkamp CT, Rot A, Volkman BF., Free PMC Article | 01/22/2022 |
| Investigation of triple-negative breast cancer risk alleles in an International African-enriched cohort. | Investigation of triple-negative breast cancer risk alleles in an International African-enriched cohort.
Martini R, Chen Y, Jenkins BD, Elhussin IA, Cheng E, Hoda SA, Ginter PS, Hanover J, Zeidan RB, Oppong JK, Adjei EK, Jibril A, Chitale D, Bensenhaver JM, Awuah B, Bekele M, Abebe E, Kyei I, Aitpillah FS, Adinku MO, Ankomah K, Osei-Bonsu EB, Nathansan SD, Jackson L, Jiagge E, Petersen LF, Proctor E, Nikolinakos P, Gyan KK, Yates C, Kittles R, Newman LA, Davis MB., Free PMC Article | 11/13/2021 |
| ACKR1 Alleles at 5.6 kb in a Well-Characterized Renewable US Food and Drug Administration (FDA) Reference Panel for Standardization of Blood Group Genotyping. | ACKR1 Alleles at 5.6 kb in a Well-Characterized Renewable US Food and Drug Administration (FDA) Reference Panel for Standardization of Blood Group Genotyping.
Srivastava K, Khil PP, Sippert E, Volkova E, Dekker JP, Rios M, Flegel WA., Free PMC Article | 11/6/2021 |
| Diversity of variant alleles encoding Kidd, Duffy, and Kell antigens in individuals with sickle cell disease using whole genome sequencing data from the NHLBI TOPMed Program. | Diversity of variant alleles encoding Kidd, Duffy, and Kell antigens in individuals with sickle cell disease using whole genome sequencing data from the NHLBI TOPMed Program.
Dinardo CL, Oliveira TGM, Kelly S, Ashley-Koch A, Telen M, Schmidt LC, Castilho S, Melo K, Dezan MR, Wheeler MM, Johnsen JM, Nickerson DA, Jain D, Custer B, Pereira AC, Sabino EC, NHLBI Recipient Epidemiology Donor Evaluation Study (REDS-III) International Component-Brazil, the Outcome Modifying Genes in SCD (OMG) study and the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program Sickle Cell Disease Working Group. | 07/10/2021 |
| Identification of ACKR1 variants associated with altered Duffy phenotype expression in blood donors from southern Brazil. | Identification of ACKR1 variants associated with altered Duffy phenotype expression in blood donors from southern Brazil.
Höher G, Rodrigues MMO, Waskow G, Agnes G, Von Burg PV, Onsten T, Fiegenbaum M, Almeida S. | 06/12/2021 |
| The DARC-null trait is associated with moderate modulation of NK cell profiles and unaltered cytolytic T cell profiles in black South Africans. | The DARC-null trait is associated with moderate modulation of NK cell profiles and unaltered cytolytic T cell profiles in black South Africans.
Naidoo KK, Shangase ZB, Rashid T, Ngubane A, Ismail N, Ndung'u T, Thobakgale CF., Free PMC Article | 01/9/2021 |
| Differential interaction between DARC and SDF-1 on erythrocytes and their precursors. | Differential interaction between DARC and SDF-1 on erythrocytes and their precursors.
Klei TRL, Aglialoro F, Mul FPJ, Tol S, Ligthart PC, Seignette IM, Geissler J, van den Akker E, van Bruggen R., Free PMC Article | 11/21/2020 |
| Increased frequency of the single nucleotide polymorphism of the DARC/ACKR1 gene associated with ethnic neutropenia in a cohort of European patients with chronic idiopathic neutropenia. | Increased frequency of the single nucleotide polymorphism of the DARC/ACKR1 gene associated with ethnic neutropenia in a cohort of European patients with chronic idiopathic neutropenia.
Fragiadaki I, Papadakis S, Sevastaki G, Sfyridaki K, Mavroudi I, Goulielmos GN, Kanellou P, Mörtberg A, Höglund P, Gemenetzi K, Stamatopoulos K, Chatzidimitriou A, Palmblad J, Papadaki HA. | 08/22/2020 |
| Decreased expression of ACKR1 was associated with cervical cancer in comparison to normal cervical tissue. The lower AKCR1 expression levels in cervical tumors correlated with poor prognosis. | Co-expression network analysis identified atypical chemokine receptor 1 (ACKR1) association with lymph node metastasis and prognosis in cervical cancer.
Liu J, Li S, Lin L, Jiang Y, Wan Y, Zhou S, Cheng W. | 08/1/2020 |
| in an Indian population, DARC 298A carriage appeared to increase the risk of malaria, and of vivax malaria in particular | Duffy antigen receptor for chemokines gene polymorphisms and malaria in Mangaluru, India.
Gai PP, van Loon W, Siegert K, Wedam J, Kulkarni SS, Rasalkar R, Boloor A, Kumar A, Jain A, Mahabala C, Baliga S, Devi R, Shenoy D, Gai P, Mockenhaupt FP., Free PMC Article | 02/1/2020 |
| DARC rs12075 SNP is associated with liver fibrosis progression in patients with chronic hepatitis C. | Impact of DARC rs12075 Variants on Liver Fibrosis Progression in Patients with Chronic Hepatitis C: A Retrospective Study.
Jiménez-Sousa MÁ, Gómez-Moreno AZ, Pineda-Tenor D, Sánchez-Ruano JJ, Artaza-Varasa T, Martin-Vicente M, Fernández-Rodríguez A, Martínez I, Resino S., Free PMC Article | 01/11/2020 |
| The most significantly associated locus was driven by rs2814778 (beta = -0.9, P = 4.21 x 10-21), a known regulatory variant in the atypical chemokine receptor 1 (ACKR1) gene. Individuals homozygous for the C allele at rs2814778 were significantly more likely to develop neutropenia and have to stop clozapine treatment (OR = 20.4, P = 3.44 x 10-7). | A genome-wide association study in individuals of African ancestry reveals the importance of the Duffy-null genotype in the assessment of clozapine-related neutropenia.
Legge SE, Pardiñas AF, Helthuis M, Jansen JA, Jollie K, Knapper S, MacCabe JH, Rujescu D, Collier DA, O'Donovan MC, Owen MJ, Walters JTR. | 12/7/2019 |
| Our study suggested that rs12075 in DARC could serve as a key predictive factor of recurrence risk in breast cancer, especially for TNBC subtype. | Effect of functional genetic variants in chemokine decoy receptors on the recurrence risk of breast cancer.
Li DD, Yang C, Shao ZM, Yu KD., Free PMC Article | 11/16/2019 |
| The authors demonstrate that staphylococcal leukocidin LukED and gamma-hemolysin HlgAB cause vascular congestion and derangements in vascular fluid distribution that rapidly cause death in mice. The Duffy antigen receptor for chemokines (DARC) on endothelial cells, rather than leukocytes or erythrocytes, is the critical target for lethality. | Staphylococcus aureus Leukocidins Target Endothelial DARC to Cause Lethality in Mice.
Lubkin A, Lee WL, Alonzo F 3rd, Wang C, Aligo J, Keller M, Girgis NM, Reyes-Robles T, Chan R, O'Malley A, Buckley P, Vozhilla N, Vasquez MT, Su J, Sugiyama M, Yeung ST, Coffre M, Bajwa S, Chen E, Martin P, Kim SY, Loomis C, Worthen GS, Shopsin B, Khanna KM, Weinstock D, Lynch AS, Koralov SB, Loke P, Cadwell K, Torres VJ., Free PMC Article | 11/9/2019 |
| DARC polymorphisms modulate the susceptibility to clinical P. vivax malaria | Susceptibility to Plasmodium vivax malaria associated with DARC (Duffy antigen) polymorphisms is influenced by the time of exposure to malaria.
Kano FS, de Souza AM, de Menezes Torres L, Costa MA, Souza-Silva FA, Sanchez BAM, Fontes CJF, Soares IS, de Brito CFA, Carvalho LH, Sousa TN., Free PMC Article | 11/2/2019 |
| Presence of high level of DARC expression with high level of heterozygosity (FyA/FyB genotype) might have a role to play in the increased susceptibility to P. vivax malaria. | Duffy antigen receptor for chemokines (DARC) and susceptibility to Plasmodium vivax malaria.
Kaur H, Sehgal R, Rani S. | 06/23/2019 |
| High-throughput Kell, Kidd, and Duffy matrix-assisted laser desorption/ionization, time-of-flight mass spectrometry-based blood group genotyping of 4000 donors shows close to full concordance with serotyping and detects new alleles. | High-throughput Kell, Kidd, and Duffy matrix-assisted laser desorption/ionization, time-of-flight mass spectrometry-based blood group genotyping of 4000 donors shows close to full concordance with serotyping and detects new alleles.
Meyer S, Vollmert C, Trost N, Brönnimann C, Gottschalk J, Buser A, Frey BM, Gassner C. | 04/22/2019 |