| Stimulation of brain alpha7-nicotinic acetylcholine receptors suppresses the rat micturition through brain GABAergic receptors. | Stimulation of brain α7-nicotinic acetylcholine receptors suppresses the rat micturition through brain GABAergic receptors.
Shimizu Y, Shimizu T, Zou S, Ono H, Hata Y, Yamamoto M, Aratake T, Shimizu S, Higashi Y, Karashima T, Saito M. | 09/11/2021 |
| In inhibitory transmission onto hippocampal CA1 pyramidal cells, deletion of all beta subunits 1, 2, and 3 completely eliminated inhibitory responses. In addition, only knockout of beta3, alone or in combination with another beta subunit, impaired inhibitory synaptic transmission. expression of beta3 alone on the background of the beta1-3 subunit knockout was sufficient to restore synaptic and extrasynaptic inhibitory ... | The GABA(A) Receptor β Subunit Is Required for Inhibitory Transmission.
Nguyen QA, Nicoll RA., Free PMC Article | 08/3/2019 |
| we conclude that is a greater contribution of beta(1) -subunit-containing GABA(A) receptors following oxygen and glucose deprivation in cerebellar Purkinje cells | Alterations in Purkinje cell GABAA receptor pharmacology following oxygen and glucose deprivation and cerebral ischemia reveal novel contribution of β1 -subunit-containing receptors.
Kelley MH, Ortiz J, Shimizu K, Grewal H, Quillinan N, Herson PS., Free PMC Article | 11/16/2013 |
| Bone marrow stem cells and adult stem cells were found to express GABA-A alpha2 and beta3, but not beta1 mRNA transcripts. | Expression of functional γ-aminobutyric acid type A receptors in Schwann-like adult stem cells.
Faroni A, Terenghi G, Magnaghi V. | 04/13/2013 |
| The endogenous sleep pathway in the hypothalamus operates through the beta1- containing GABAAR whereas inhibition of neuronal firing (anaesthesia) by low propofol doses relies on beta3- containing GABAAR. | GABAA receptors involved in sleep and anaesthesia: β1- versus β3-containing assemblies.
Yanovsky Y, Schubring S, Fleischer W, Gisselmann G, Zhu XR, Lübbert H, Hatt H, Rudolph U, Haas HL, Sergeeva OA. | 06/23/2012 |
| Following spinal nerve ligation, activated microglia in the spinal cord modulate peripheral nerve injury-induced downregulation of GABA(B)R1a receptor expression in the spinal dorsal horn. | p38/MAPK inhibitor modulates the expression of dorsal horn GABA(B) receptors in the spinal nerve ligation model of neuropathic pain.
Wu J, Xu Y, Pu S, Jiang W, Du D. | 02/11/2012 |
| beta1-containing GABA(A)Rs are expressed in the hypothalamus | Fragrant dioxane derivatives identify beta1-subunit-containing GABAA receptors.
Sergeeva OA, Kletke O, Kragler A, Poppek A, Fleischer W, Schubring SR, Görg B, Haas HL, Zhu XR, Lübbert H, Gisselmann G, Hatt H., Free PMC Article | 09/20/2010 |
| GABA(B) receptors expressed by neurones in solitary nucleus may be involved in cardiovascular regulation and that changes in GABA(B) mRNA expression levels may contribute to the hypertensive state in SHR | Increased GABA B receptor subtype expression in the nucleus of the solitary tract of the spontaneously hypertensive rat.
Spary EJ, Maqbool A, Saha S, Batten TF. | 01/21/2010 |
| falling progesterone levels may be associated with expression of new receptors of the alpha4beta1delta subtype in periaqueductal gray | Withdrawal from progesterone increases expression of alpha4, beta1, and delta GABA(A) receptor subunits in neurons in the periaqueductal gray matter in female Wistar rats.
Griffiths J, Lovick T. | 01/21/2010 |
| In rats with hepatic encephalopathy, mRNA expression levels of GABA(A) receptor subunits alpha(1), beta(1), gamma(2) increase significantly in basal nuclei, substantia nigra and hippocampi | Expression of gamma-aminobutyric acid A receptor subunits alpha1, beta1, gamma2 mRNA in rats with hepatic encephalopathy.
Li XQ, Dong L, Liu ZH, Luo JY., Free PMC Article | 01/21/2010 |
| a serine at position 265 is critical in conferring an open state of the beta1 subunit-containing GABAA receptors in the absence of agonist | A TM2 residue in the beta1 subunit determines spontaneous opening of homomeric and heteromeric gamma-aminobutyric acid-gated ion channels.
Miko A, Werby E, Sun H, Healey J, Zhang L. | 01/21/2010 |
| Increased expression of GABA(A) receptor beta 1 subunit in the interneurones of the periaqueductal gray matter could render the panic circuitry abnormally excitable by disinhibiting ongoing GABAergic inhibition. | Changes in GABA(A) receptor subunit expression in the midbrain during the oestrous cycle in Wistar rats.
Lovick TA, Griffiths JL, Dunn SM, Martin IL. | 01/21/2010 |
| Results provide evidence for a conserved pore opening mechanism in anion-selective members of the ligand-gated ion channel family, including glycine receptors (GlyR) and gamma-aminobutyric acid, type A receptors (GABA(A)R). | Comparative surface accessibility of a pore-lining threonine residue (T6') in the glycine and GABA(A) receptors.
Shan Q, Haddrill JL, Lynch JW. | 01/21/2010 |
| Activity-dependent bidirectional regulation of receptor channels by the 5-HT(4) receptor-mediated signalling in rat prefrontal cortical pyramidal neurons. | Activity-dependent bidirectional regulation of GABA(A) receptor channels by the 5-HT(4) receptor-mediated signalling in rat prefrontal cortical pyramidal neurons.
Cai X, Flores-Hernandez J, Feng J, Yan Z., Free PMC Article | 01/21/2010 |
| GABA(B1) subunit mRNA signals were moderately expressed in the cerebral cortex neuroepithelium of discrete brain regions on gestational day (GD) 11.5 and 12.5 and were highly expressed in the brain and spinal cord on GD 13.5 and 15.5. | Prenatal alteration and distribution of the GABA(B1) and GABA(B2) receptor subunit mRNAs during rat central nervous system development.
Li S, Park MS, Kim MO. | 01/21/2010 |