| Association between genetically proxied PCSK9 inhibition and systemic lupus erythematosus risk: A mendelian randomization study. | Association between genetically proxied PCSK9 inhibition and systemic lupus erythematosus risk: A mendelian randomization study.
Ji X, Guo HY, Han M, Peng H, Yuan H. | 04/8/2024 |
| The Impact of PCSK9 Gene Polymorphisms on Ischemic Stroke: A Systematic Review and Meta-Analysis. | The Impact of PCSK9 Gene Polymorphisms on Ischemic Stroke: A Systematic Review and Meta-Analysis.
Wang J, Li S, Ren Y, Wang G, Li W. | 04/3/2024 |
| Sex and statin-related genetic associations at the PCSK9 gene locus: results of genome-wide association meta-analysis. | Sex and statin-related genetic associations at the PCSK9 gene locus: results of genome-wide association meta-analysis.
Pott J, Kheirkhah A, Gadin JR, Kleber ME, Delgado GE, Kirsten H, Forer L, Hauck SM, Burkhardt R, Scharnagl H, Loeffler M, März W, Thiery J, Gieger C, Peters A, Silveira A, Hooft FV, Kronenberg F, Scholz M., Free PMC Article | 03/29/2024 |
| PCSK9 increases vulnerability of carotid plaque by promoting mitochondrial dysfunction and apoptosis of vascular smooth muscle cells. | PCSK9 increases vulnerability of carotid plaque by promoting mitochondrial dysfunction and apoptosis of vascular smooth muscle cells.
Xu R, Li T, Luo J, Zhang X, Wang T, Wang Y, Ma Y, Yang B, Jia J, Dmytriw AA, Li W, Jiao L., Free PMC Article | 02/26/2024 |
| Proteome-wide mendelian randomization investigates potential associations in heart failure and its etiology: emphasis on PCSK9. | Proteome-wide mendelian randomization investigates potential associations in heart failure and its etiology: emphasis on PCSK9.
Lin L, Yu H, Xue Y, Wang L, Zhu P., Free PMC Article | 02/26/2024 |
| GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal. | GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal.
Senftleber NK, Andersen MK, Jørsboe E, Stæger FF, Nøhr AK, Garcia-Erill G, Meisner J, Santander CG, Balboa RF, Gilly A, Bjerregaard P, Larsen CVL, Grarup N, Jørgensen ME, Zeggini E, Moltke I, Hansen T, Albrechtsen A., Free PMC Article | 02/15/2024 |
| Polymorphisms rs562556 and rs2479409 of the PCSK9 gene associated with obesity and cardiovascular disease. | Polymorphisms rs562556 and rs2479409 of the PCSK9 gene associated with obesity and cardiovascular disease.
Vašková H, Poráčová J, Šlebodová M, Kalafutová S, Konečná M, Sedlák V, Kimáková T, Mydlárová Blaščáková M. | 02/6/2024 |
| PCSK9 regulates myofibroblast transformation through the JAK2/STAT3 pathway to regulate fibrosis after myocardial infarction. | PCSK9 regulates myofibroblast transformation through the JAK2/STAT3 pathway to regulate fibrosis after myocardial infarction.
Bao H, Wang X, Zhou H, Zhou W, Liao F, Wei F, Yang S, Luo Z, Li W. | 02/2/2024 |
| Longitudinal variation of serum PCSK9 in ulcerative colitis: association with disease activity, T helper 1/2/17 cells, and clinical response of tumor necrosis factor inhibitor. | Longitudinal variation of serum PCSK9 in ulcerative colitis: association with disease activity, T helper 1/2/17 cells, and clinical response of tumor necrosis factor inhibitor.
Deng J, Jiang Y, Luan L, Fu S, Huang M, Dai Z, Liao Y, Guo S, Fu Y. | 01/30/2024 |
| Role of proprotein convertase subtilisin/kexin type 9 (PCSK9) in diabetic complications. | Role of proprotein convertase subtilisin/kexin type 9 (PCSK9) in diabetic complications.
Imaralu OE, Aluganti Narasimhulu C, Singal PK, Singla DK. | 01/8/2024 |
| Dynamics of the personalities of PCSK9 on missense variants (rs505151 and rs562556) from elderly cohort studies in Brazil. | Dynamics of the personalities of PCSK9 on missense variants (rs505151 and rs562556) from elderly cohort studies in Brazil.
Galvão Lopes V, Fernandes de Oliveira V, Mendonça Munhoz Dati L, Naslavsky MS, Ferreira GM, Hirata MH. | 12/26/2023 |
| Meta-GWAS on PCSK9 concentrations reveals associations of novel loci outside the PCSK9 locus in White populations. | Meta-GWAS on PCSK9 concentrations reveals associations of novel loci outside the PCSK9 locus in White populations.
Kheirkhah A, Schachtl-Riess JF, Lamina C, Di Maio S, Koller A, Schönherr S, Coassin S, Forer L, Sekula P, Gieger C, Peters A, Köttgen A, Eckardt KU, Kronenberg F. | 12/20/2023 |
| Screening and verifying the mutations in the LDLR and APOB genes in a Chinese family with familial hypercholesterolemia. | Screening and verifying the mutations in the LDLR and APOB genes in a Chinese family with familial hypercholesterolemia.
Lv X, Wang C, Liu L, Yin G, Zhang W, Abdu FA, Shi T, Zhang Q, Che W., Free PMC Article | 11/30/2023 |
| Induced alternative splicing an opportunity to study PCSK9 protein isoforms at physiologically relevant concentrations. | Induced alternative splicing an opportunity to study PCSK9 protein isoforms at physiologically relevant concentrations.
Cale JM, Ham KA, Li D, McIntosh CS, Watts GF, Wilton SD, Aung-Htut MT., Free PMC Article | 11/29/2023 |
| Data-driven transcriptomics analysis identifies PCSK9 as a novel key regulator in liver aging. | Data-driven transcriptomics analysis identifies PCSK9 as a novel key regulator in liver aging.
Arif M, Matyas C, Mukhopadhyay P, Yokus B, Trojnar E, Paloczi J, Paes-Leme B, Zhao S, Lohoff FW, Haskó G, Pacher P., Free PMC Article | 11/22/2023 |
| Exploring PCSK9 Genetic Impact on Lipoprotein(a) via Dual Approaches: Association and Mendelian Randomization. | Exploring PCSK9 Genetic Impact on Lipoprotein(a) via Dual Approaches: Association and Mendelian Randomization.
Chang YC, Hsu LA, Ko YL., Free PMC Article | 11/15/2023 |
| Elevated circulating PCSK9 level is associated with 28-day mortality in patients with sepsis: a prospective cohort study. | Elevated circulating PCSK9 level is associated with 28-day mortality in patients with sepsis: a prospective cohort study.
Shu Y, Deng Z, Deng Y, Zhou J, Wang J, Duan Z, Jiang T, Zhao X, Shi Z, Qiu C., Free PMC Article | 11/1/2023 |
| PCSK9, a novel immune and ferroptosis related gene in abdominal aortic aneurysm neck. | PCSK9, a novel immune and ferroptosis related gene in abdominal aortic aneurysm neck.
Zhuang J, Zhu H, Cheng Z, Hu X, Yu X, Li J, Liu H, Tang P, Zhang Y, Xiong X, Deng H., Free PMC Article | 10/20/2023 |
| Exploring the Link between Plasma Levels of PCSK9, Immune Dysregulation and Atherosclerosis in Patients with Primary Sjogren's Syndrome. | Exploring the Link between Plasma Levels of PCSK9, Immune Dysregulation and Atherosclerosis in Patients with Primary Sjögren's Syndrome.
Bianconi V, Cafaro G, Mannarino MR, Perricone C, Cosentini E, Bistoni O, Paltriccia R, Lombardini R, Gerli R, Pirro M, Bartoloni E., Free PMC Article | 10/5/2023 |
| Association of circulatory PCSK-9 with biomarkers of redox imbalance and inflammatory cascades in the prognosis of diabetes and associated complications: a pilot study in the Indian population. | Association of circulatory PCSK-9 with biomarkers of redox imbalance and inflammatory cascades in the prognosis of diabetes and associated complications: a pilot study in the Indian population.
Waiz M, Alvi SS, Khan MS. | 10/4/2023 |
| PCSK9 and the nervous system: a no-brainer? | PCSK9 and the nervous system: a no-brainer?
Jaafar AK, Techer R, Chemello K, Lambert G, Bourane S., Free PMC Article | 09/26/2023 |
| Proprotein convertase subtilisin/kexin type 9 targets megalin in the kidney proximal tubule and aggravates proteinuria in nephrotic syndrome. | Proprotein convertase subtilisin/kexin type 9 targets megalin in the kidney proximal tubule and aggravates proteinuria in nephrotic syndrome.
Skeby CK, Hummelgaard S, Gustafsen C, Petrillo F, Frederiksen KP, Olsen D, Kristensen T, Ivarsen P, Madsen P, Christensen EI, Nielsen R, Birn H, Glerup S, Weyer K. | 09/25/2023 |
| PCSK9 Involvement in Autism Etiology: Sequence Variations, Protein Concentration, and Promoter Methylation. | PCSK9 Involvement in Autism Etiology: Sequence Variations, Protein Concentration, and Promoter Methylation.
Salem S, Mosaad R, Lotfy R, Ashaat E, Ismail S. | 09/12/2023 |
| PCSK9 inhibition interrupts the cross-talk between keratinocytes and macrophages and prevents UVB-induced skin damage. | PCSK9 inhibition interrupts the cross-talk between keratinocytes and macrophages and prevents UVB-induced skin damage.
Luan C, He Y, Liu W, Rong Y, Gao J, Xu K, Yu H, Hu Y, Zhang J, Chen K, Guo W., Free PMC Article | 09/6/2023 |
| Proprotein convertase subtilisin/kexin type 9 (PCSK9) in the central nervous system. | Proprotein convertase subtilisin/kexin type 9 (PCSK9) in the central nervous system.
Bell AS, Wagner J, Rosoff DB, Lohoff FW. | 08/25/2023 |