| RAD54B promotes gastric cancer cell migration and angiogenesis via the Wnt/beta-catenin pathway. | RAD54B promotes gastric cancer cell migration and angiogenesis via the Wnt/β-catenin pathway.
Li J, Geng H, Li X, Zou S, Xu X., Free PMC Article | 02/23/2024 |
| RNA-sequencing analysis reveals the potential molecular mechanism of RAD54B in the proliferation of inflamed human dental pulp cells. | RNA-sequencing analysis reveals the potential molecular mechanism of RAD54B in the proliferation of inflamed human dental pulp cells.
Huang P, Wang F, Wang X, Meng X, Qiao W, Meng L. | 12/17/2022 |
| RAD54B mutations enhance the sensitivity of ovarian cancer cells to poly(ADP-ribose) polymerase (PARP) inhibitors. | RAD54B mutations enhance the sensitivity of ovarian cancer cells to poly(ADP-ribose) polymerase (PARP) inhibitors.
Liu P, Lin C, Liu L, Lu Z, Tu Z, Liu H., Free PMC Article | 10/29/2022 |
| Integrated study of miR-215 promoting breast cancer cell apoptosis by targeting RAD54B. | Integrated study of miR-215 promoting breast cancer cell apoptosis by targeting RAD54B.
Wang M, Liao J, Tan C, Zhou H, Wang J, Wang K, Li Y, Wu W., Free PMC Article | 09/18/2021 |
| RAD54B exerts an oncogenic role in lung cancer cell proliferation. | Knockdown of RAD54B expression reduces cell proliferation and induces apoptosis in lung cancer cells.
Xu C, Liu D, Mei H, Hu J, Luo M., Free PMC Article | 05/9/2020 |
| the biological role of RAD54B in the neoplastic process of luminal A breast cancer, is reported. | RAD54B potentiates tumor growth and predicts poor prognosis of patients with luminal A breast cancer.
Zhang Z, Li X, Han Y, Ji T, Huang X, Gao Q, Ma D. | 02/8/2020 |
| Results demonstrate that the patched 1 protein (PTCH1) rs10512248 and DNA repair and recombination protein RAD54B (RAD54B) rs12681366 were significantly associated with non-syndromic orofacial clefts (NSOC) in a Northern Chinese population. | Association between PTCH1 and RAD54B single-nucleotide polymorphisms and non-syndromic orofacial clefts in a northern Chinese population.
Liu X, Yang S, Meng L, Chen C, Hui X, Jiang Y, Jiao X, Lv K, Song T. | 09/21/2019 |
| miR-139-3p target genes ISG20L2, RAD54B, KIAA0101, and PIGS were significantly negatively correlated with miR-139-3p expression in patients with hepatocellular carcinoma. | High miR-139-3p expression predicts a better prognosis for hepatocellular carcinoma: a pooled analysis.
Zhu Y, Zhou C, He Q., Free PMC Article | 06/8/2019 |
| High RAD54B expression is associated with hepatoma. | Inhibition of RAD54B suppresses proliferation and promotes apoptosis in hepatoma cells.
Wang R, Li Y, Chen Y, Wang L, Wu Q, Guo Y, Li Y, Liu J, Wang L., Free PMC Article | 11/10/2018 |
| Review of structural aspects of RAD54B, molecular functions associated with its cellular roles in preventing genome instability, and how aberrant function contributes to oncogenesis. | The enigmatic oncogene and tumor suppressor-like properties of RAD54B: Insights into genome instability and cancer.
McAndrew EN, McManus KJ. | 09/16/2017 |
| RAD54B expression has potential to serve as a novel prognostic biomarker, particularly for distant recurrence in colorectal cancer | High RAD54B expression: an independent predictor of postoperative distant recurrence in colorectal cancer patients.
Nagai Y, Yamamoto Y, Yasuhara T, Hata K, Nishikawa T, Tanaka T, Tanaka J, Kiyomatsu T, Kawai K, Nozawa H, Kazama S, Yamaguchi H, Ishihara S, Sunami E, Yamanaka T, Miyagawa K, Watanabe T., Free PMC Article | 06/28/2016 |
| Patients with expression of both FEN1 and RAD54B were prone to have advanced nodal involvement and significantly poor prognosis. | The Overexpression of FEN1 and RAD54B May Act as Independent Prognostic Factors of Lung Adenocarcinoma.
Hwang JC, Sung WW, Tu HP, Hsieh KC, Yeh CM, Chen CJ, Tai HC, Hsu CT, Shieh GS, Chang JG, Yeh KT, Liu TC., Free PMC Article | 06/11/2016 |
| The scaffolding function of Rad54B dynamically regulates the maintenance of genome integrity by limiting checkpoint strength. | Rad54B serves as a scaffold in the DNA damage response that limits checkpoint strength.
Yasuhara T, Suzuki T, Katsura M, Miyagawa K. | 02/27/2016 |
| support a model in which RAD54L and RAD54B counteract genome-destabilizing effects of direct binding of RAD51 to dsDNA in tumor cells | RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells.
Mason JM, Dusad K, Wright WD, Grubb J, Budke B, Heyer WD, Connell PP, Weichselbaum RR, Bishop DK., Free PMC Article | 06/27/2015 |
| RAD54B-deficient cells are selectively killed relative to controls via siRNA-based silencing of SOD1 | Synthetic lethal targeting of superoxide dismutase 1 selectively kills RAD54B-deficient colorectal cancer cells.
Sajesh BV, Bailey M, Lichtensztejn Z, Hieter P, McManus KJ., Free PMC Article | 06/7/2014 |
| RAD54B and GREB1 gene polymorphisms may not be associated with PCOS in the Han Chinese population. | Replication study of RAD54B and GREB1 polymorphisms and risk of PCOS in Han Chinese.
Wang Z, Li T, Xing X, Gao X, Zhang X, You L, Zhao H, Ma J, Chen ZJ. | 04/12/2014 |
| These results suggest that hINO80 assists double-strand break repair by positively regulating the expression of the Rad54B and XRCC3 genes. | Human INO80 chromatin-remodelling complex contributes to DNA double-strand break repair via the expression of Rad54B and XRCC3 genes.
Park EJ, Hur SK, Kwon J. | 10/23/2010 |
| Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | Gamma-radiation sensitivity and polymorphisms in RAD51L1 modulate glioma risk.
Liu Y, Shete S, Wang LE, El-Zein R, Etzel CJ, Liang FW, Armstrong G, Tsavachidis S, Gilbert MR, Aldape KD, Xing J, Wu X, Wei Q, Bondy ML., Free PMC Article | 09/15/2010 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array.
Kweekel DM, Antonini NF, Nortier JW, Punt CJ, Gelderblom H, Guchelaar HJ., Free PMC Article | 08/12/2009 |
| RAD54B-deficient human colorectal cancer cells are sensitive to synthetic lethal killing by reduced FEN1 expression, while isogenic RAD54B proficient cells are not | Specific synthetic lethal killing of RAD54B-deficient human colorectal cancer cells by FEN1 silencing.
McManus KJ, Barrett IJ, Nouhi Y, Hieter P., Free PMC Article | 01/21/2010 |
| S100A11 targets Rad54B to sites of DNA DSB repair sites and has a role in p21-based regulation of cell cycle | Rad54B targeting to DNA double-strand break repair sites requires complex formation with S100A11.
Murzik U, Hemmerich P, Weidtkamp-Peters S, Ulbricht T, Bussen W, Hentschel J, von Eggeling F, Melle C., Free PMC Article | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (3) articlesVariation within DNA repair pathway genes and risk of multiple sclerosis.
Briggs FB, Goldstein BA, McCauley JL, Zuvich RL, De Jager PL, Rioux JD, Ivinson AJ, Compston A, Hafler DA, Hauser SL, Oksenberg JR, Sawcer SJ, Pericak-Vance MA, Haines JL, Barcellos LF, International Multiple Sclerosis Genetics Consortium. Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk.
McWilliams RR, Bamlet WR, de Andrade M, Rider DN, Couch FJ, Cunningham JM, Matsumoto ME, Rabe KG, Hammer TJ, Petersen GM. Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.
Mavaddat N, Dunning AM, Ponder BA, Easton DF, Pharoah PD. | 02/11/2009 |
| RAD54B binding may affect the quaternary structure of DMC1. | Biochemical analysis of the N-terminal domain of human RAD54B.
Sarai N, Kagawa W, Fujikawa N, Saito K, Hikiba J, Tanaka K, Miyagawa K, Kurumizaka H, Yokoyama S., Free PMC Article | 01/21/2010 |
| Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) | Common variants in immune and DNA repair genes and risk for human papillomavirus persistence and progression to cervical cancer.
Wang SS, Bratti MC, Rodríguez AC, Herrero R, Burk RD, Porras C, González P, Sherman ME, Wacholder S, Lan ZE, Schiffman M, Chanock SJ, Hildesheim A., Free PMC Article | 11/26/2008 |
| Rad54B is a DNA-dependent ATPase and has biochemical properties different from its structural homolog in yeast, Tid1/Rdh54 | Human Rad54B is a double-stranded DNA-dependent ATPase and has biochemical properties different from its structural homolog in yeast, Tid1/Rdh54.
Tanaka K, Kagawa W, Kinebuchi T, Kurumizaka H, Miyagawa K., Free PMC Article | 01/21/2010 |