U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    DCAF13 DDB1 and CUL4 associated factor 13 [ Homo sapiens (human) ]

    Gene ID: 25879, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    DCAF13 promotes ovarian cancer progression by activating FRAS1-mediated FAK signaling pathway.

    DCAF13 promotes ovarian cancer progression by activating FRAS1-mediated FAK signaling pathway.
    Tang ZY, Wang XM, Xu CW, Sun QQ, Hua YX, Zhou QY, Hu HY, Liu SB, Guo YJ, Ao L, Che X, Zhang XC, Heger M, Zheng X, Liu AJ, Wang Q, Zhan ZJ, Cheng SQ, Pan WW., Free PMC Article

    10/7/2024
    CRL4[DCAF13] E3 ubiquitin ligase targets MeCP2 for degradation to prevent DNA hypermethylation and ensure normal transcription in growing oocytes.

    CRL4(DCAF13) E3 ubiquitin ligase targets MeCP2 for degradation to prevent DNA hypermethylation and ensure normal transcription in growing oocytes.
    Ren P, Tong X, Li J, Jiang H, Liu S, Li X, Lai M, Yang W, Rong Y, Zhang Y, Jin J, Ma Y, Pan W, Fan HY, Zhang S, Zhang YL., Free PMC Article

    04/10/2024
    A biallelic variant of DCAF13 implicated in a neuromuscular disorder in humans.

    A biallelic variant of DCAF13 implicated in a neuromuscular disorder in humans.
    Manzoor H, Zahid H, Emerling CA, Kumar KR, Hussain HMJ, Seo GH, Wajid M, Naz S., Free PMC Article

    06/21/2023
    A multidimensional pan-cancer analysis of DCAF13 and its protumorigenic effect in lung adenocarcinoma.

    A multidimensional pan-cancer analysis of DCAF13 and its protumorigenic effect in lung adenocarcinoma.
    Wei S, Lu K, Xing J, Yu W.

    03/10/2023
    DCAF13 is essential for the pathogenesis of preeclampsia through its involvement in endometrial decidualization.

    DCAF13 is essential for the pathogenesis of preeclampsia through its involvement in endometrial decidualization.
    Yan X, Rong M, Zhou Q, Zhang C.

    09/24/2022
    DCAF13 promotes breast cancer cell proliferation by ubiquitin inhibiting PERP expression.

    DCAF13 promotes breast cancer cell proliferation by ubiquitin inhibiting PERP expression.
    Shan BQ, Wang XM, Zheng L, Han Y, Gao J, Lv MD, Zhang Y, Liu YX, Zhang H, Chen HS, Ao L, Zhang YL, Lu X, Wu ZJ, Xu Y, Che X, Heger M, Cheng SQ, Pan WW, Zhang X., Free PMC Article

    05/28/2022
    Doxorubicin promotes breast cancer cell migration and invasion via DCAF13.

    Doxorubicin promotes breast cancer cell migration and invasion via DCAF13.
    Sun Z, Zhou D, Yang J, Zhang D., Free PMC Article

    04/9/2022
    DCAF13 promotes triple-negative breast cancer metastasis by mediating DTX3 mRNA degradation.

    DCAF13 promotes triple-negative breast cancer metastasis by mediating DTX3 mRNA degradation.
    Liu J, Li H, Mao A, Lu J, Liu W, Qie J, Pan G., Free PMC Article

    12/4/2021
    The DCAF13 deficiency resulted in pre-rRNA accumulation in oocytes, whereas the total mRNA level was not altered. Further exploration showed that DCAF13 participated in the 18S rRNA processing in growing oocytes.

    Mammalian nucleolar protein DCAF13 is essential for ovarian follicle maintenance and oocyte growth by mediating rRNA processing.
    Zhang J, Zhang YL, Zhao LW, Guo JX, Yu JL, Ji SY, Cao LR, Zhang SY, Shen L, Ou XH, Fan HY., Free PMC Article

    09/26/2020
    Two novel variants in the DCAF13 and NOV genes were identified that are associated with familial cortical myoclonic tremor with epilepsy in a Chinese pedigree.

    Whole exome sequencing reveals novel NOV and DCAF13 variants in a Chinese pedigree with familial cortical myoclonic tremor with epilepsy.
    Lin H, Hu N, Zhang Y, Wang Y, Macdonald RL.

    02/23/2019
    our findings revealed that the overexpression of DCAF13 in hepatocellular carcinoma was significantly associated with poor survival and may participate in the regulation of cell cycle progression

    The overexpression and prognostic role of DCAF13 in hepatocellular carcinoma.
    Cao J, Hou P, Chen J, Wang P, Wang W, Liu W, Liu C, He X.

    07/22/2017
    This study suggests that non-synonymous WDSOF1 polymorphisms play a role in the genetic susceptibility to osteoporosis.

    Identification of non-synonymous polymorphisms in the WDSOF1 gene as novel susceptibility markers for low bone mineral density in Japanese postmenopausal women.
    Urano T, Shiraki M, Usui T, Sasaki N, Ouchi Y, Inoue S, Urano T, Shiraki M, Usui T, Sasaki N, Ouchi Y, Inoue S.

    01/29/2011
    Observational study of gene-disease association. (HuGE Navigator)

    Identification of non-synonymous polymorphisms in the WDSOF1 gene as novel susceptibility markers for low bone mineral density in Japanese postmenopausal women.
    Urano T, Shiraki M, Usui T, Sasaki N, Ouchi Y, Inoue S, Urano T, Shiraki M, Usui T, Sasaki N, Ouchi Y, Inoue S.

    09/15/2010
    firstprevious page of 1 nextlast