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    MYCBP MYC binding protein [ Homo sapiens (human) ]

    Gene ID: 26292, updated on 19-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Circ_0002669 promotes osteosarcoma tumorigenesis through directly binding to MYCBP and sponging miR-889-3p.

    Circ_0002669 promotes osteosarcoma tumorigenesis through directly binding to MYCBP and sponging miR-889-3p.
    Zhang Y, Zhan Y, Liu Z, Guo H, Liu D, Chen C., Free PMC Article

    04/8/2024
    MiR-26b-5p inhibits cell proliferation and EMT by targeting MYCBP in triple-negative breast cancer.

    MiR-26b-5p inhibits cell proliferation and EMT by targeting MYCBP in triple-negative breast cancer.
    Ma S, Wei H, Wang C, Han J, Chen X, Li Y., Free PMC Article

    03/19/2022
    TAZ is indispensable for c-MYC-induced hepatocarcinogenesis.

    TAZ is indispensable for c-MYC-induced hepatocarcinogenesis.
    Wang H, Zhang S, Zhang Y, Jia J, Wang J, Liu X, Zhang J, Song X, Ribback S, Cigliano A, Evert M, Liang B, Wu H, Calvisi DF, Zeng Y, Chen X., Free PMC Article

    02/19/2022
    lncRNA LUNAR1 accelerates colorectal cancer progression by targeting the miR4953p/MYCBP axis.

    lncRNA LUNAR1 accelerates colorectal cancer progression by targeting the miR‑495‑3p/MYCBP axis.
    Qian J, Garg A, Li F, Shen Q, Xiao K., Free PMC Article

    09/18/2021
    Weighted gene co-expression network analysis identifies specific modules and hub genes related to subsyndromal symptomatic depression.

    Weighted gene co-expression network analysis identifies specific modules and hub genes related to subsyndromal symptomatic depression.
    Geng R, Li Z, Yu S, Yuan C, Hong W, Wang Z, Wang Q, Yi Z, Fang Y.

    03/13/2021
    lnc-XLEC1 had inhibitive effects that may result from its collaboration with MBP-1 (MYCBP).

    X chromosome-linked long noncoding RNA lnc-XLEC1 regulates c-Myc-dependent cell growth by collaborating with MBP-1 in endometrial cancer.
    Li F, Li H, Zhang L, Li W, Deng J, An M, Wu S, Lu X, Ma R, Wang Y, Guo B, Lu J, Zhou Y.

    12/14/2019
    Data found that MYCBP was highly expressed in hepatocellular carcinoma (HCC) tissues. Its overexpression is correlated with poor prognosis which indicates that MYCBP might play a cancer-promoting role in HCC. Further results found that EYA4 suppressed HCC tumor cell growth by repressing MYCBP by dephosphorylating beta-catenin S552.

    EYA4 inhibits hepatocellular carcinoma by repressing MYCBP by dephosphorylating β-catenin at Ser552.
    Zhu XX, Li JH, Cai JP, Hou X, Huang CS, Huang XT, Wang JQ, Li SJ, Xu QC, Yin XY., Free PMC Article

    10/12/2019
    Through activating MYCBP and by sponging miR-574-5p.

    Non-coding RNA MFI2-AS1 promotes colorectal cancer cell proliferation, migration and invasion through miR-574-5p/MYCBP axis.
    Li C, Tan F, Pei Q, Zhou Z, Zhou Y, Zhang L, Wang D, Pei H., Free PMC Article

    08/3/2019
    c-Myc expression is reduced in pterygium compared with normal conjunctiva.

    Downregulation of c-Myc in pterygium and cultured pterygial cells.
    Cui D, Pan Z, Zhang S, Zheng J, Huang Q, Wu K.

    03/3/2012
    Suppression of telomerase activity mediated by PinX1 is involved in the Mad1/c-Myc pathway.

    PinX1 inhibits telomerase activity in gastric cancer cells through Mad1/c-Myc pathway.
    Wang HB, Wang XW, Zhou G, Wang WQ, Sun YG, Yang SM, Fang DC.

    11/13/2010
    miR-22 acts as a tumor suppressor through direct repression of MYCBP expression and subsequent reduction of oncogenic c-Myc activities.

    Tumor-suppressive microRNA-22 inhibits the transcription of E-box-containing c-Myc target genes by silencing c-Myc binding protein.
    Xiong J, Du Q, Liang Z.

    10/23/2010
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
    An important role for MBP-1 in the altered cell proliferation and energy utilization that occur in response to an altered glucose concentration.

    c-myc promoter binding protein regulates the cellular response to an altered glucose concentration.
    Sedoris KC, Thomas SD, Miller DM.

    01/21/2010
    identified a novel AMY-1-binding protein, AAT-1, and determied its expression profiles, genes, and cellular localization; results showed that AAT-1 was specifically expressed in the testis throughout spermatogenesis and was also present in mature sperm

    AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex with AMY-1, A-kinase anchor protein 84, and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase.
    Yukitake H, Furusawa M, Taira T, Iguchi-Ariga SM, Ariga H.

    01/21/2010
    interacts with S-AKAP84 and AKAP95 in the cytoplasm and the nucleus, respectively, and inhibits enzyme acdtivity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex

    AMY-1 interacts with S-AKAP84 and AKAP95 in the cytoplasm and the nucleus, respectively, and inhibits cAMP-dependent protein kinase activity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex.
    Furusawa M, Taira T, Iguchi-Ariga SM, Ariga H.

    01/21/2010
    AMY-1 coordinates ADP-Ribosylation Factors-mediated membrane trafficking and signaling pathways.

    AMY-1 (associate of Myc-1) localization to the trans-Golgi network through interacting with BIG2, a guanine-nucleotide exchange factor for ADP-ribosylation factors.
    Ishizaki R, Shin HW, Iguchi-Ariga SM, Ariga H, Nakayama K.

    01/21/2010
    AMY-1 was localized in the mitochondria of HeLa and sperm in association with AKAP149 and S-AKAP84, respectively. These results suggest that AMY-1 plays a role in spermatogenesis

    AMY-1, a c-Myc-binding protein, is localized in the mitochondria of sperm by association with S-AKAP84, an anchor protein of cAMP-dependent protein kinase.
    Furusawa M, Ohnishi T, Taira T, Iguchi-Ariga SM, Ariga H.

    10/17/2001
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