| Emerging Role of the IL-36/IL-36R Axis in Multiple Inflammatory Skin Diseases. | Emerging Role of the IL-36/IL-36R Axis in Multiple Inflammatory Skin Diseases.
Ahmad F, Alam MA, Ansari AW, Jochebeth A, Leo R, Al-Abdulla MN, Al-Khawaga S, AlHammadi A, Al-Malki A, Al Naama K, Ahmad A, Buddenkotte J, Steinhoff M. | 02/6/2024 |
| Altered Gene Expression of IL-35 and IL-36alpha in the Skin of Patients with Atopic Dermatitis. | Altered Gene Expression of IL-35 and IL-36α in the Skin of Patients with Atopic Dermatitis.
Zysk W, Sitko K, Tukaj S, Zaryczańska A, Trzeciak M., Free PMC Article | 01/16/2024 |
| The Emerging Roles of IL-36, IL-37, and IL-38 in Diabetes Mellitus and its Complications. | The Emerging Roles of IL-36, IL-37, and IL-38 in Diabetes Mellitus and its Complications.
Huang G, Li M, Tian X, Jin Q, Mao Y, Li Y. | 09/24/2022 |
| IL-36 Cytokines: Their Roles in Asthma and Potential as a Therapeutic. | IL-36 Cytokines: Their Roles in Asthma and Potential as a Therapeutic.
Dong H, Hao Y, Li W, Yang W, Gao P., Free PMC Article | 08/6/2022 |
| IL-36 is Closely Related to Neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease. | IL-36 is Closely Related to Neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease.
Huang S, Feng T, Wang J, Dong L., Free PMC Article | 06/18/2022 |
| Interleukin-36alpha is elevated in diffuse systemic sclerosis and may potentiate fibrosis. | Interleukin-36α is elevated in diffuse systemic sclerosis and may potentiate fibrosis.
O'Reilly S. | 06/18/2022 |
| IL-36alpha and IL-36gamma expressions in the differential diagnosis of palmoplantar psoriasis and palmoplantar eczema: A retrospective histopathologic and immunohistochemical study. | IL-36α and IL-36γ expressions in the differential diagnosis of palmoplantar psoriasis and palmoplantar eczema: A retrospective histopathologic and immunohistochemical study.
Erdem O, Leblebici C, Koku Aksu AE, Erdil D, Kara Polat A, Gürel MS. | 03/19/2022 |
| Interleukin-36alpha inhibits colorectal cancer metastasis by enhancing the infiltration and activity of CD8(+) T lymphocytes. | Interleukin-36α inhibits colorectal cancer metastasis by enhancing the infiltration and activity of CD8(+) T lymphocytes.
Wei X, Yao Y, Wang X, Sun J, Zhao W, Qiu L, Zhai W, Qi Y, Gao Y, Wu Y. | 02/12/2022 |
| Interleukin-36alpha suppresses growth of non-small cell lung cancer in vitro by reducing angiogenesis. | Interleukin-36α suppresses growth of non-small cell lung cancer in vitro by reducing angiogenesis.
Xie X, Hu H, He J, Liu Y, Guo F, Luo F, Jiang M, Wang L., Free PMC Article | 01/8/2022 |
| Decreased serum profile of the interleukin-36alpha in polycystic ovary syndrome. | Decreased serum profile of the interleukin-36α in polycystic ovary syndrome.
Eroglu S, Cakmakliogullari EK. | 12/11/2021 |
| Elevated urinary IL-36alpha and IL-18 levels are associated with diabetic nephropathy in patients with type 2 diabetes mellitus. | Elevated urinary IL-36α and IL-18 levels are associated with diabetic nephropathy in patients with type 2 diabetes mellitus.
Chakraborty R, Parveen R, Varshney P, Kapur P, Khatoon S, Saha N, Agarwal NB. | 11/6/2021 |
| Serum IL-36 cytokines levels in type 2 diabetes mellitus patients and their association with obesity, insulin resistance, and inflammation. | Serum IL-36 cytokines levels in type 2 diabetes mellitus patients and their association with obesity, insulin resistance, and inflammation.
Li Y, Chen S, Zhao T, Li M., Free PMC Article | 10/30/2021 |
| Role of IL-36 Cytokines in the Regulation of Angiogenesis Potential of Trophoblast Cells. | Role of IL-36 Cytokines in the Regulation of Angiogenesis Potential of Trophoblast Cells.
Murrieta-Coxca JM, Gutiérrez-Samudio RN, El-Shorafa HM, Groten T, Rodríguez-Martínez S, Cancino-Diaz ME, Cancino-Diaz JC, Favaro RR, Markert UR, Morales-Prieto DM., Free PMC Article | 09/18/2021 |
| Association of interleukin-36alpha gene expression in Egyptian patients with systemic lupus erythematosus with organ involvement and disease activity. | Association of interleukin-36α gene expression in Egyptian patients with systemic lupus erythematosus with organ involvement and disease activity.
Mohamed AE, Zaki HM, Hosny MM, Fouad MM, Moneim NHA. | 07/3/2021 |
| Structural insights into heme binding to IL-36alpha proinflammatory cytokine. | Structural insights into heme binding to IL-36α proinflammatory cytokine.
Wißbrock A, Goradia NB, Kumar A, Paul George AA, Kühl T, Bellstedt P, Ramachandran R, Hoffmann P, Galler K, Popp J, Neugebauer U, Hampel K, Zimmermann B, Adam S, Wiendl M, Krönke G, Hamza I, Heinemann SH, Frey S, Hueber AJ, Ohlenschläger O, Imhof D., Free PMC Article | 11/21/2020 |
| Biology of IL-36 Signaling and Its Role in Systemic Inflammatory Diseases. | Biology of IL-36 Signaling and Its Role in Systemic Inflammatory Diseases.
Yuan ZC, Xu WD, Liu XY, Liu XY, Huang AF, Su LC., Free PMC Article | 10/24/2020 |
| IL-36 s in the colorectal cancer: is interleukin 36 good or bad for the development of colorectal cancer? | IL-36 s in the colorectal cancer: is interleukin 36 good or bad for the development of colorectal cancer?
Chen F, Qu M, Zhang F, Tan Z, Xia Q, Hambly BD, Bao S, Tao K., Free PMC Article | 10/3/2020 |
| These findings highlight the relevance of TGFBR2-IL-36 interplay in joint homeostasis. | TGF-β type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis.
Li T, Chubinskaya S, Esposito A, Jin X, Tagliafierro L, Loeser R, Hakimiyan AA, Longobardi L, Ozkan H, Spagnoli A., Free PMC Article | 07/18/2020 |
| The interleukin-36 (IL-36) pathway appears to be central to generalized pustular psoriasis (GPP) pathogenesis. | An update on generalized pustular psoriasis.
Gooderham MJ, Van Voorhees AS, Lebwohl MG. | 06/20/2020 |
| interleukin-36 alpha levels are elevated in the serum and cerebrospinal fluid of patients with neuromyelitis optica spectrum disorder and correlate with disease activity | Interleukin-36 alpha levels are elevated in the serum and cerebrospinal fluid of patients with neuromyelitis optica spectrum disorder and correlate with disease activity.
Song Y, Zhu M, Liu C, Zheng C, Zhou Y, Zhu J, Jin T. | 02/29/2020 |
| IL36A expression is significantly downregulated in healhty palatal mucosa of smokers | Whole transcriptome analysis of smoker palatal mucosa identifies multiple downregulated innate immunity genes.
Wang Y, Anderson EP, Tatakis DN. | 11/18/2019 |
| The molecular analysis revealed strong cooperative effects of IL-17A and IL-36 cytokines in regulating target genes, which was dependent on the proteolytic activation of the latter. Together these findings suggest an amplification cycle that can be initiated by IL-17A, involving IL-36 cytokines and immune cell derived proteases and resulting in active IL-36 cytokines which synergize with IL-17A | The psoriasis-associated IL-17A induces and cooperates with IL-36 cytokines to control keratinocyte differentiation and function.
Pfaff CM, Marquardt Y, Fietkau K, Baron JM, Lüscher B., Free PMC Article | 07/6/2019 |
| PTX3 and IL36alpha serum levels are increased in systemic lupus erythematosus patients when compared to normal control subjects | Serum Levels of Pentraxin3 and Interlukin36 in Patients with Systemic Lupus and their Relation to Disease Activity.
Ismail SM, Abd-ELWahab MK, Mohamed MS. | 05/18/2019 |
| The authors report that, in Mycobacterium tuberculosis-infected macrophages, IL-36 signaling modulates cholesterol biosynthesis and efflux via LXR. | IL-36/LXR axis modulates cholesterol metabolism and immune defense to Mycobacterium tuberculosis.
Ahsan F, Maertzdorf J, Guhlich-Bornhof U, Kaufmann SHE, Moura-Alves P., Free PMC Article | 12/22/2018 |
| serum IL-36alpha levels were higher in active systemic lupus erythematosus patients and correlated with disease activity and arthritis | Increased serum IL-36α and IL-36γ levels in patients with systemic lupus erythematosus: Association with disease activity and arthritis.
Mai SZ, Li CJ, Xie XY, Xiong H, Xu M, Zeng FQ, Guo Q, Han YF. | 10/27/2018 |