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    PDCD4 programmed cell death 4 [ Homo sapiens (human) ]

    Gene ID: 27250, updated on 12-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    PDCD4 interacting with PIK3CB and CTSZ promotes the apoptosis of multiple myeloma cells.

    PDCD4 interacting with PIK3CB and CTSZ promotes the apoptosis of multiple myeloma cells.
    Liu L, Feng X, Fan C, Kong D, Feng X, Sun C, Xu Y, Li B, Jiang Y, Zheng C.

    09/4/2024
    STAT1 mediated downregulation of the tumor suppressor gene PDCD4, is driven by the atypical cadherin FAT1, in glioblastoma.

    STAT1 mediated downregulation of the tumor suppressor gene PDCD4, is driven by the atypical cadherin FAT1, in glioblastoma.
    Khan MT, Almas M, Malik N, Jalota A, Sharma S, Ali SA, Luthra K, Suri V, Suri A, Basak S, Seth P, Chosdol K, Sinha S.

    06/5/2024
    MicroRNA-181b-5p Facilitates Thyroid Cancer Growth via Targeting Programmed Cell Death 4.

    MicroRNA-181b-5p Facilitates Thyroid Cancer Growth via Targeting Programmed Cell Death 4.
    Geng X, Li Y, Sun Y, Cao L, Song Z.

    05/30/2024
    PDCD4 deficiency improved 4-vinylcyclohexene dioxide-induced mouse premature ovarian insufficiency.

    PDCD4 deficiency improved 4-vinylcyclohexene dioxide-induced mouse premature ovarian insufficiency.
    Zhang J, Qin M, Kao C, Shi Y, Yang Z, Chen T, Liu M, Fang L, Gao F, Qin Y, Ding L.

    05/9/2024
    Progress on the relationship between tumor suppressor PDCD4 and diseases based on the analysis of structural characteristics.

    Progress on the relationship between tumor suppressor PDCD4 and diseases based on the analysis of structural characteristics.
    Li H, Wu GM.

    05/1/2024
    [PDCD4 knockdown ameliorates lipopolysaccharide-induced endothelial cell damage by improving mitochondrial dynamics].

    [PDCD4 knockdown ameliorates lipopolysaccharide-induced endothelial cell damage by improving mitochondrial dynamics].
    Yu J, Li R, Xia T, Wang J, Jin J, Yuan M, Li M., Free PMC Article

    02/8/2024
    Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4.

    Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4.
    Sun RW, Zhang H, Mehdi SJ, Richter GT, Bowman HH, Sifford J, Smith C, Burnett AK, Layman A, Washam CL, Byrum SD, Bennett JT, Jensen DM, Dmyterko V, Perkins JA, Shawber CJ, Wu JK, Strub GM.,

    09/25/2023
    PRMT5 knockdown enhances cell viability and suppresses cell apoptosis, oxidative stress, inflammation and endothelial dysfunction in ox-LDL-induced vascular endothelial cells via interacting with PDCD4.

    PRMT5 knockdown enhances cell viability and suppresses cell apoptosis, oxidative stress, inflammation and endothelial dysfunction in ox-LDL-induced vascular endothelial cells via interacting with PDCD4.
    Fei X, Cen X, Zhao R, Wang J, Cui H.

    08/28/2023
    Cryo-EM Structure of Human Tumor Suppressor Protein Pdcd4 Bound to the Ribosome.

    Cryo-EM Structure of Human Tumor Suppressor Protein Pdcd4 Bound to the Ribosome.
    Querido JB, Sokabe M, Díaz-López I, Gordiyenko Y, Zuber P, Du Y, Albacete-Albacete L, Fraser CS, Ramakrishnan V.

    08/25/2023
    Gastric Cancer Growth Modulated by circSNTB2/miR-6938-5p/G0S2 and PDCD4.

    Gastric Cancer Growth Modulated by circSNTB2/miR-6938-5p/G0S2 and PDCD4.
    Rong B, Chen X, Xie G, Han L, Chen H, Sun Q, Zhou Y., Free PMC Article

    06/22/2023
    MiR-93-5p inhibits retinal neurons apoptosis by regulating PDCD4 in acute ocular hypertension model.

    MiR-93-5p inhibits retinal neurons apoptosis by regulating PDCD4 in acute ocular hypertension model.
    Tan C, Shi W, Zhang Y, Liu C, Hu T, Chen D, Huang J., Free PMC Article

    06/15/2023
    Induction of premature senescence and a less-fibrogenic phenotype by programmed cell death 4 knockdown in the human hepatic stellate cell line Lieming Xu-2.

    Induction of premature senescence and a less-fibrogenic phenotype by programmed cell death 4 knockdown in the human hepatic stellate cell line Lieming Xu-2.
    Perveen R, Ozaki I, Manirujjaman M, Mine K, Murata Y, Tanaka K, Xia J, Takahashi H, Anzai K, Matsuhashi S., Free PMC Article

    02/28/2023
    Tumor Suppressor p53 Down-Regulates Programmed Cell Death Protein 4 (PDCD4) Expression.

    Tumor Suppressor p53 Down-Regulates Programmed Cell Death Protein 4 (PDCD4) Expression.
    Yang WH, George AP, Wang CM, Yang RH, Duncan AM, Patel D, Neil ZD, Yang WH., Free PMC Article

    02/28/2023
    eIF4A/PDCD4 Pathway, a Factor for Doxorubicin Chemoresistance in a Triple-Negative Breast Cancer Cell Model.

    eIF4A/PDCD4 Pathway, a Factor for Doxorubicin Chemoresistance in a Triple-Negative Breast Cancer Cell Model.
    González-Ortiz A, Pulido-Capiz A, Castañeda-Sánchez CY, Ibarra-López E, Galindo-Hernández O, Calderón-Fernández MA, López-Cossio LY, Díaz-Molina R, Chimal-Vega B, Serafín-Higuera N, Córdova-Guerrero I, García-González V., Free PMC Article

    01/11/2023
    Downregulation of PDCD4 by deSUMOylation associates with the progression of gestational trophoblastic disease.

    Downregulation of PDCD4 by deSUMOylation associates with the progression of gestational trophoblastic disease.
    Wang YX, Cui L, Wu WB, Quinn MJ, Menon R, Zhao JR, Zhang HJ.

    12/10/2022
    Circ_0030998 Restrains Cisplatin Resistance Through Mediating miR-1323/PDCD4 Axis in Non-small Cell Lung Cancer.

    Circ_0030998 Restrains Cisplatin Resistance Through Mediating miR-1323/PDCD4 Axis in Non-small Cell Lung Cancer.
    Zhu C, Jiang X, Xiao H, Guan J.

    11/5/2022
    Circular RNA hsa_circ_0026344 suppresses gastric cancer cell proliferation, migration and invasion via the miR-590-5p/PDCD4 axis.

    Circular RNA hsa_circ_0026344 suppresses gastric cancer cell proliferation, migration and invasion via the miR-590-5p/PDCD4 axis.
    Lv L, Du J, Wang D, Yan Z.

    08/27/2022
    LncRNA SLC16A1-AS1 regulates the miR-182/PDCD4 axis and inhibits the triple-negative breast cancer cell cycle.

    LncRNA SLC16A1-AS1 regulates the miR-182/PDCD4 axis and inhibits the triple-negative breast cancer cell cycle.
    Jiang B, Liu Q, Gai J, Guan J, Li Q.

    08/6/2022
    TRIM27 regulates the expression of PDCD4 by the ubiquitinproteasome pathway in ovarian and endometrial cancer cells.

    TRIM27 regulates the expression of PDCD4 by the ubiquitin‑proteasome pathway in ovarian and endometrial cancer cells.
    Yu H, Wan L, Tang Z, Yao C, Zhang D, Jiang M, Wang C, Liu Y, Xue C, Wang X, Shi Y, Zhang L, Wang X, Wei Z.

    05/28/2022
    Knockdown of circ_0007290 alleviates oxygen-glucose deprivation-induced neuronal injury by regulating miR-496/PDCD4 axis.

    Knockdown of circ_0007290 alleviates oxygen-glucose deprivation-induced neuronal injury by regulating miR-496/PDCD4 axis.
    Wang F, Liu J, Wang D, Yao Y, Jiao X.

    04/16/2022
    MiR-429 prohibited NF-kappaB signalling to alleviate contrast-induced acute kidney injury via targeting PDCD4.

    MiR-429 prohibited NF-κB signalling to alleviate contrast-induced acute kidney injury via targeting PDCD4.
    Niu HM, Guo LQ, Qiao YH, Jiao HY.

    04/2/2022
    Low PDCD4 Expression Is Associated With Poor Prognosis of Colorectal Carcinoma.

    Low PDCD4 Expression Is Associated With Poor Prognosis of Colorectal Carcinoma.
    Kim JY, Lee H, Kim EK, Lee WM, Hong YO, Hong SA.

    03/12/2022
    Hsa_circ_0008259 modulates miR-21-5p and PDCD4 expression to restrain osteosarcoma progression.

    Hsa_circ_0008259 modulates miR-21-5p and PDCD4 expression to restrain osteosarcoma progression.
    Guan K, Liu S, Duan K, Zhang X, Liu H, Xu B, Wang X, Jin X., Free PMC Article

    02/19/2022
    MicroRNA-15a-5p plays a role in osteogenic MC3T3-E1 cells differentiation by targeting PDCD4 (programmed cell death 4) via Wnt/beta-catenin dependent signaling pathway.

    MicroRNA-15a-5p plays a role in osteogenic MC3T3-E1 cells differentiation by targeting PDCD4 (programmed cell death 4) via Wnt/β-catenin dependent signaling pathway.
    Wang Q, Miao Y, Qian Z, Chen L, Lu T, Xu Y, Jiang X, Shen Y., Free PMC Article

    02/19/2022
    Exosomal miR-208b related with oxaliplatin resistance promotes Treg expansion in colorectal cancer.

    Exosomal miR-208b related with oxaliplatin resistance promotes Treg expansion in colorectal cancer.
    Ning T, Li J, He Y, Zhang H, Wang X, Deng T, Liu R, Li H, Bai M, Fan Q, Zhu K, Ying G, Ba Y., Free PMC Article

    02/12/2022
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