| CircRNA RNF10 inhibits tumorigenicity by targeting miR-942-5p/GOLIM4 axis in breast cancer. | CircRNA RNF10 inhibits tumorigenicity by targeting miR-942-5p/GOLIM4 axis in breast cancer.
Kan B, Yan G, Shao Y, Zhang Z, Xue H. | 11/19/2022 |
| RBFOX2/GOLIM4 Splicing Axis Activates Vesicular Transport Pathway to Promote Nasopharyngeal Carcinogenesis. | RBFOX2/GOLIM4 Splicing Axis Activates Vesicular Transport Pathway to Promote Nasopharyngeal Carcinogenesis.
Luo CL, Xu XC, Liu CJ, He S, Chen JR, Feng YC, Liu SQ, Peng W, Zhou YQ, Liu YX, Wei PP, Li B, Mai HQ, Xia XJ, Bei JX., Free PMC Article | 12/25/2021 |
| MiR-105-3p acts as an oncogene to promote the proliferation and metastasis of breast cancer cells by targeting GOLIM4. | MiR-105-3p acts as an oncogene to promote the proliferation and metastasis of breast cancer cells by targeting GOLIM4.
Lin B, Liu C, Shi E, Jin Q, Zhao W, Wang J, Ji R., Free PMC Article | 05/8/2021 |
| This study found that GOLIM4, as the target gene downstream of STIM1, inhibited the proliferation of head and neck cancer, promoted apoptosis, and regulated cell cycle progression, and GOLIM4 is a novel oncogene in head and neck cancer and might help in developing promising targetted therapies for head and neck cancer patients. | Golgi integral membrane protein 4 manipulates cellular proliferation, apoptosis, and cell cycle in human head and neck cancer.
Bai Y, Cui X, Gao D, Wang Y, Wang B, Wang W., Free PMC Article | 04/20/2019 |
| Authors provide evidence that Mn-induced exit of GPP130 from the trans-Golgi network (TGN) toward lysosomes is mediated by the sorting receptor sortilin interacting with the lumenal stem domain of GPP130. | Manganese-induced trafficking and turnover of GPP130 is mediated by sortilin.
Venkat S, Linstedt AD., Free PMC Article | 12/2/2017 |
| Findings suggest the unexpected presence of quality control in the Golgi that recognizes aggregated Golgi proteins, GPP130, and targets them for degradation in lysosomes. | Induced oligomerization targets Golgi proteins for degradation in lysosomes.
Tewari R, Bachert C, Linstedt AD., Free PMC Article | 10/22/2016 |
| Characteristics of GPP130 and its STx/STx1 binding interface. | Shiga toxin-binding site for host cell receptor GPP130 reveals unexpected divergence in toxin-trafficking mechanisms.
Mukhopadhyay S, Redler B, Linstedt AD., Free PMC Article | 03/1/2014 |
| the stem domain of GPP130 is a novel Mn sensor in the Golgi lumen of mammalian cells | Manganese-induced trafficking and turnover of the cis-Golgi glycoprotein GPP130.
Mukhopadhyay S, Bachert C, Smith DR, Linstedt AD., Free PMC Article | 08/9/2010 |
| Multiple pH-regulated steps affect the trafficking of GPP130. | Both post-Golgi and intra-Golgi cycling affect the distribution of the Golgi phosphoprotein GPP130.
Starr T, Forsten-Williams K, Storrie B. | 01/21/2010 |
| both the translation and transcription are regulated independent of the cell cycle and dissociated from the duplication of the centrosome | Expression of Golgi membrane protein p138 is cell cycle-independent and dissociated from centrosome duplication.
Doi K, Noma S, Yamao F, Goko H, Yagura T. | 01/21/2010 |
| GPP130 mediates exit from endosomes and thereby underlies Shiga toxin invasion and retrieval-based targeting of other cycling Golgi proteines | A cycling cis-Golgi protein mediates endosome-to-Golgi traffic.
Natarajan R, Linstedt AD., Free PMC Article | 01/21/2010 |