Pyruvate metabolism dictates fibroblast sensitivity to GLS1 inhibition during fibrogenesis.
Contento G, Wilson JA, Selvarajah B, Platé M, Guillotin D, Morales V, Trevisani M, Pitozzi V, Bianchi K, Chambers RC., Free PMC Article

CircCOL1A1 promotes proliferation, migration, and invasion of colorectal cancer (CRC) cells and glutamine metabolism through GLS1 up-regulation by sponging miR-214-3p.
Liu J, Zhang X, Yang M, Zhang X., Free PMC Article

Glutaminase potentiates the glycolysis in esophageal squamous cell carcinoma by interacting with PDK1.
Zhu G, Guan F, Li S, Zhang Q, Zhang X, Qin Y, Sun Z, Peng S, Cheng J, Li Y, Ren R, Fan T, Liu H.

Glutaminase (GLS1) gene expression in primary breast cancer.
Vidula N, Yau C, Rugo HS.

SIRT4 protects against intestinal fibrosis by facilitating GLS1 degradation.
Xue X, Zeng X, Wu X, Mu K, Dai Y, Wei Z.

LncRNA PVT1 Confers Cisplatin Resistance of Esophageal Cancer Cells through Modulating the miR-181a-5p-Glutaminase (GLS) Axis.
Chen Z, Wang Q, Huang L, Xu G, Hu J.

Association between GLS Gene Polymorphisms and the Susceptibility to Lung Cancer in the Chinese Han Population.
Wang Y, Chen M, Yi F, Xu J, Liu C, Zhang Z, Wang P, Jin T, Chen M.

Combined thioredoxin reductase and glutaminase inhibition exerts synergistic anti-tumor activity in MYC-high high-grade serous ovarian carcinoma.
Raninga PV, He Y, Datta KK, Lu X, Maheshwari UR, Venkat P, Mayoh C, Gowda H, Kalimutho M, Hooper JD, Khanna KK., Free PMC Article

Regulation of Cardiac Fibroblast GLS1 Expression by Scleraxis.
Chattopadhyaya S, Nagalingam RS, Ledingham DA, Moffatt TL, Al-Hattab DS, Narhan P, Stecy MT, O'Hara KA, Czubryt MP., Free PMC Article

Increased C reactive protein, cardiac troponin I and GLS are associated with myocardial inflammation in patients with non-ischemic heart failure.
Schwuchow-Thonke S, Göbel S, Emrich T, Schmitt VH, Fueting F, Klank C, Escher F, Schultheiss HP, Münzel T, Keller K, Wenzel P., Free PMC Article

Circ_0000003 regulates glutamine metabolism and tumor progression of tongue squamous cell carcinoma via the miR‑330‑3p/GLS axis.
Qian C, Chen S, Li S, Wang Y, Yao J., Free PMC Article

A glutaminase isoform switch drives therapeutic resistance and disease progression of prostate cancer.
Xu L, Yin Y, Li Y, Chen X, Chang Y, Zhang H, Liu J, Beasley J, McCaw P, Zhang H, Young S, Groth J, Wang Q, Locasale JW, Gao X, Tang DG, Dong X, He Y, George D, Hu H, Huang J., Free PMC Article

GLS1 depletion inhibited colorectal cancer proliferation and migration via redox/Nrf2/autophagy-dependent pathway.
Liu HY, Zhang HS, Liu MY, Li HM, Wang XY, Wang M.

Glutaminase isoforms expression switches microRNA levels and oxidative status in glioblastoma cells.
de Los Santos-Jiménez J, Campos-Sandoval JA, Márquez-Torres C, Urbano-Polo N, Brøndegaard D, Martín-Rufián M, Lobo C, Peñalver A, Gómez-García MC, Martín-Campos J, Cardona C, Castilla L, da Costa Souza F, Cheng T, Segura JA, Alonso FJ, Curi R, Colquhoun A, DeBerardinis RJ, Márquez J, Matés JM., Free PMC Article

A facile and sensitive method of quantifying glutaminase binding to its inhibitor CB-839 in tissues.
Chen Y, Zhao Y, Bajor DL, Wang Z, Selfridge JE., Free PMC Article

Targeting Hepatic Glutaminase 1 Ameliorates Non-alcoholic Steatohepatitis by Restoring Very-Low-Density Lipoprotein Triglyceride Assembly.
Simon J, Nuñez-García M, Fernández-Tussy P, Barbier-Torres L, Fernández-Ramos D, Gómez-Santos B, Buqué X, Lopitz-Otsoa F, Goikoetxea-Usandizaga N, Serrano-Macia M, Rodriguez-Agudo R, Bizkarguenaga M, Zubiete-Franco I, Gutiérrez-de Juan V, Cabrera D, Alonso C, Iruzubieta P, Romero-Gomez M, van Liempd S, Castro A, Nogueiras R, Varela-Rey M, Falcón-Pérez JM, Villa E, Crespo J, Lu SC, Mato JM, Aspichueta P, Delgado TC, Martínez-Chantar ML., Free PMC Article

The role of CA-125, GLS and FASN in predicting cytoreduction for epithelial ovarian cancers.
Winarno GNA, Hidayat YM, Soetopo S, Krisnadi SR, Tobing MDL, Rauf S., Free PMC Article

SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells.
Tong Y, Guo D, Lin SH, Liang J, Yang D, Ma C, Shao F, Li M, Yu Q, Jiang Y, Li L, Fang J, Yu R, Lu Z.

SIRT4 is the molecular switch mediating cellular proliferation in colorectal cancer through GLS mediated activation of AKT/GSK3β/CyclinD1 pathway.
Cui Y, Bai Y, Yang J, Yao Y, Zhang C, Liu C, Shi J, Li Q, Zhang J, Lu X, Zhang Y.

Upregulation of GLS1 Isoforms KGA and GAC Facilitates Mitochondrial Metabolism and Cell Proliferation in Epstein-Barr Virus Infected Cells.
Krishna G, Soman Pillai V, Valiya Veettil M., Free PMC Article

GLS1-mediated glutaminolysis unbridled by MALT1 protease promotes psoriasis pathogenesis.
Xia X, Cao G, Sun G, Zhu L, Tian Y, Song Y, Guo C, Wang X, Zhong J, Zhou W, Li P, Zhang H, Hao J, Li Z, Deng L, Yin Z, Gao Y., Free PMC Article

Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders.
Johmura Y, Yamanaka T, Omori S, Wang TW, Sugiura Y, Matsumoto M, Suzuki N, Kumamoto S, Yamaguchi K, Hatakeyama S, Takami T, Yamaguchi R, Shimizu E, Ikeda K, Okahashi N, Mikawa R, Suematsu M, Arita M, Sugimoto M, Nakayama KI, Furukawa Y, Imoto S, Nakanishi M.

Inhibition of the MYC-Regulated Glutaminase Metabolic Axis Is an Effective Synthetic Lethal Approach for Treating Chemoresistant Ovarian Cancers.
Shen YA, Hong J, Asaka R, Asaka S, Hsu FC, Suryo Rahmanto Y, Jung JG, Chen YW, Yen TT, Tomaszewski A, Zhang C, Attarwala N, DeMarzo AM, Davidson B, Chuang CM, Chen X, Gaillard S, Le A, Shih IM, Wang TL., Free PMC Article

NUDT21 suppresses the growth of small cell lung cancer by modulating GLS1 splicing.
Gao CC, Xu QQ, Xiao FJ, Wang H, Wu CT, Wang LS.

Targeting cellular metabolism to reduce head and neck cancer growth.
Yang J, Guo Y, Seo W, Zhang R, Lu C, Wang Y, Luo L, Paul B, Yan W, Saxena D, Li X., Free PMC Article