| The Atypical Chemerin Receptor GPR1 Displays Different Modes of Interaction with beta-Arrestins in Humans and Mice with Important Consequences on Subcellular Localization and Trafficking. | The Atypical Chemerin Receptor GPR1 Displays Different Modes of Interaction with β-Arrestins in Humans and Mice with Important Consequences on Subcellular Localization and Trafficking.
Degroot GN, Lepage V, Parmentier M, Springael JY., Free PMC Article | 04/23/2022 |
| Chemerin causes lipid metabolic imbalance and induces passive lipid accumulation in human hepatoma cell line via the receptor GPR1. | Chemerin causes lipid metabolic imbalance and induces passive lipid accumulation in human hepatoma cell line via the receptor GPR1.
Zhu L, Huang J, Wang Y, Yang Z, Chen X. | 07/10/2021 |
| Chemerin Isoform-Specific Effects on Hepatocyte Migration and Immune Cell Inflammation. | Chemerin Isoform-Specific Effects on Hepatocyte Migration and Immune Cell Inflammation.
Feder S, Bruckmann A, McMullen N, Sinal CJ, Buechler C., Free PMC Article | 02/27/2021 |
| GPR1 protein and gene levels were significantly decreased in gestational diabetes mellitus patient placentas. | Impact of GPR1 signaling on maternal high-fat feeding and placenta metabolism in mice.
Huang B, Huang C, Zhao H, Zhu W, Wang B, Wang H, Chen J, Xiao T, Niu J, Zhang J. | 01/4/2020 |
| The majority of presented data report down-regulation of chemerin in cancer tissue and suggest a tumor-suppressing role of chemerin in most cancer types, being mediated by recruiting innate immune defenses and by growth-inhibitory downstream signaling by chemerin receptors CMKLR1 and GPR1. (Review) | Chemerin and Cancer.
Treeck O, Buechler C, Ortmann O., Free PMC Article | 01/4/2020 |
| CMKLR1 and GPR1 were widely expressed in vascular smooth muscle. | Chemerin Elicits Potent Constrictor Actions via Chemokine-Like Receptor 1 (CMKLR1), not G-Protein-Coupled Receptor 1 (GPR1), in Human and Rat Vasculature.
Kennedy AJ, Yang P, Read C, Kuc RE, Yang L, Taylor EJ, Taylor CW, Maguire JJ, Davenport AP., Free PMC Article | 12/23/2017 |
| The Gene-based analyses revealed four significant associations in the WT1, ZC3H12C, DLGAP2, and GPR1 genes at p < 0.05. in this study. | Genetic variation in imprinted genes is associated with risk of late-onset Alzheimer's disease.
Chaudhry M, Wang X, Bamne MN, Hasnain S, Demirci FY, Lopez OL, Kamboh MI., Free PMC Article | 10/31/2015 |
| GPR1 gene is imprinted and paternally expressed in human and mouse. | A tripartite paternally methylated region within the Gpr1-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chip.
Hiura H, Sugawara A, Ogawa H, John RM, Miyauchi N, Miyanari Y, Horiike T, Li Y, Yaegashi N, Sasaki H, Kono T, Arima T., Free PMC Article | 10/22/2013 |
| identified homologous amino acid sequences in amino-terminal regions between CCR5 and GPR1/ sequences are important for G protein-coupled receptors to make the conformation critical for the interaction with the Env protein of HIV-1. | Short communication: identification of the conformational requirement for the specificities of coreceptors for human and simian immunodeficiency viruses.
Shimizu N, Tanaka A, Jinno-Oue A, Mori T, Ohtsuki T, Hoshino H. | 06/14/2010 |
| Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size.
Soranzo N, Rivadeneira F, Chinappen-Horsley U, Malkina I, Richards JB, Hammond N, Stolk L, Nica A, Inouye M, Hofman A, Stephens J, Wheeler E, Arp P, Gwilliam R, Jhamai PM, Potter S, Chaney A, Ghori MJ, Ravindrarajah R, Ermakov S, Estrada K, Pols HA, Williams FM, McArdle WL, van Meurs JB, Loos RJ, Dermitzakis ET, Ahmadi KR, Hart DJ, Ouwehand WH, Wareham NJ, Barroso I, Sandhu MS, Strachan DP, Livshits G, Spector TD, Uitterlinden AG, Deloukas P., Free PMC Article | 08/12/2009 |
| Observational study of gene-disease association. (HuGE Navigator) | G protein-coupled receptor for asthma susceptibility associates with respiratory distress syndrome.
Pulkkinen V, Haataja R, Hannelius U, Helve O, Pitkänen OM, Karikoski R, Rehn M, Marttila R, Lindgren CM, Hästbacka J, Andersson S, Kere J, Hallman M, Laitinen T. | 03/13/2008 |
| GPR1 is a senescence-associated gene in normal human oral keratinocytes. | Senescence-associated genes in normal human oral keratinocytes.
Kang MK, Kameta A, Shin KH, Baluda MA, Kim HR, Park NH. | 01/21/2010 |
| Data report that a synthetic peptide derived from the NH2-terminal extracellular region of an orphan GPCR, GPR1, inhibited infection of not only an HIV-1 variant that uses GPR1 as a co-receptor, but also X4, R5, and R5X4 viruses. | The synthetic peptide derived from the NH2-terminal extracellular region of an orphan G protein-coupled receptor, GPR1, preferentially inhibits infection of X4 HIV-1.
Jinno-Oue A, Shimizu N, Soda Y, Tanaka A, Ohtsuki T, Kurosaki D, Suzuki Y, Hoshino H. | 01/21/2010 |