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    IFNL3 interferon lambda 3 [ Homo sapiens (human) ]

    Gene ID: 282617, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Predictive Potential Of Il28b Gene In Hcv Patients, Resistant To Daclatasvir And Sofosbuvir In KPK Population.

    Predictive Potential Of Il28b Gene In Hcv Patients, Resistant To Daclatasvir And Sofosbuvir In KPK Population.
    Sardar S, Muhammad S, Haq M, Haq NU, Kashif Khan AM.

    02/28/2024
    IFN-lambda3 is induced by Leishmania donovani and can inhibit parasite growth in cell line models but not in the mouse model, while it shows a significant association with leishmaniasis in humans.

    IFN-λ3 is induced by Leishmania donovani and can inhibit parasite growth in cell line models but not in the mouse model, while it shows a significant association with leishmaniasis in humans.
    De M, Sukla S, Bharatiya S, Keshri S, Roy DG, Roy S, Dutta D, Saha S, Ejazi SA, Ravichandiran V, Ali N, Chatterjee M, Chinnaswamy S., Free PMC Article

    02/20/2024
    Its all about IFN-lambda4: Protective role of IFNL4 polymorphism against COVID-19-related pneumonia in females.

    Its all about IFN-λ4: Protective role of IFNL4 polymorphism against COVID-19-related pneumonia in females.
    Matic S, Milovanovic D, Mijailovic Z, Djurdjevic P, Sazdanovic P, Stefanovic S, Todorovic D, Popovic S, Vitosevic K, Vukicevic V, Vukic M, Vukovic N, Milivojevic N, Zivanovic M, Jakovljevic V, Filipovic N, Djordjevic N, Baskic D.

    10/10/2023
    IFN-lambda3 and CCL17 as predictors of disease progression in patients with mild to moderate COVID-19: A cohort study in a real-world setting.

    IFN-λ3 and CCL17 as predictors of disease progression in patients with mild to moderate COVID-19: A cohort study in a real-world setting.
    Sekimoto Y, Sekiya M, Nojiri S, Hayakawa E, Masui Y, Tajima M, Nishino K, Nishizaki Y, Takahashi K., Free PMC Article

    03/1/2023
    IFNL3/4 polymorphisms as a two-edged sword: An association with COVID-19 outcome.

    IFNL3/4 polymorphisms as a two-edged sword: An association with COVID-19 outcome.
    Matic S, Milovanovic D, Mijailovic Z, Djurdjevic P, Sazdanovic P, Stefanovic S, Todorovic D, Popovic S, Vitosevic K, Vukicevic V, Vukic M, Vukovic N, Milivojevic N, Zivanovic M, Jakovljevic V, Filipovic N, Baskic D, Djordjevic N.

    03/1/2023
    The Impact of interferon lambda 3 Polymorphism on Hepato-Cellular Carcinoma Progression in Hepatitis C Virus Patients: Treatment-Naive and Experienced.

    The Impact of interferon lambda 3 Polymorphism on Hepato-Cellular Carcinoma Progression in Hepatitis C Virus Patients: Treatment-Naïve and Experienced.
    Abd Elrahman M, Ibrahim MK, Khairy A, Yosry A, Zayed N, Tawefeek S, Barakat AZ, Elbatae H, Bader El Din NG., Free PMC Article

    02/4/2023
    Assessment of serum interleukin-28 as a biomarker to predict mortality in traumatic patients with sepsis.

    Assessment of serum interleukin-28 as a biomarker to predict mortality in traumatic patients with sepsis.
    Yang Y, Chen J, Yi C, Yang F, Tang M, Li Z, Bai X.

    08/20/2022
    IL28B, TLR7 SNPs, and cytomegalovirus infection are risk factors for advanced liver disease in chronic hepatitis C patients.

    IL28B, TLR7 SNPs, and cytomegalovirus infection are risk factors for advanced liver disease in chronic hepatitis C patients.
    Khalil FO, Alsebaey A, Kasemy ZA, Abdelmageed SM, Bedair HM, Abdelsattar S.

    04/30/2022
    PNPLA3 and IL 28B signature for predicting susceptibility to chronic hepatitis C infection and fibrosis progression.

    PNPLA3 and IL 28B signature for predicting susceptibility to chronic hepatitis C infection and fibrosis progression.
    Youssef SS, Abbas EAER, Youness RA, Elemeery MN, Nasr AS, Seif S.

    04/9/2022
    The association between interferon lambda 3 and 4 gene single-nucleotide polymorphisms and the recovery of COVID-19 patients.

    The association between interferon lambda 3 and 4 gene single-nucleotide polymorphisms and the recovery of COVID-19 patients.
    Rahimi P, Tarharoudi R, Rahimpour A, Mosayebi Amroabadi J, Ahmadi I, Anvari E, Siadat SD, Aghasadeghi M, Fateh A., Free PMC Article

    01/29/2022
    Possible relationship between IL28B rs12979860 and TLR2 -196 to -174 del/ins polymorphisms and the liver fibrosis stage in hepatitis C patients.

    Possible relationship between IL28B rs12979860 and TLR2 -196 to -174 del/ins polymorphisms and the liver fibrosis stage in hepatitis C patients.
    Öksüz Z, Üçbilek E, Serin MS, Yaraş S, Temel GÖ, Sezgin O.

    01/22/2022
    Association Between IL28B, IL29 Gene Polymorphisms and Clinical Manifestations of Behcet's Disease.

    Association Between IL28B, IL29 Gene Polymorphisms and Clinical Manifestations of Behçet's Disease.
    Cakmak Genc G, Karakas Celık S, Kocaaga A, Koca R, Dursun A.

    01/22/2022
    Functional genetic variants of the IFN-lambda3 (IL28B) gene and transcription factor interactions on its promoter.

    Functional genetic variants of the IFN-λ3 (IL28B) gene and transcription factor interactions on its promoter.
    Roy S, Guha Roy D, Bhushan A, Bharatiya S, Chinnaswamy S., Free PMC Article

    01/22/2022
    Evaluation of miR-122 Serum Level and IFN-lambda3 Genotypes in Patients with Chronic HCV and HCV-Infected Liver Transplant Candidate.

    Evaluation of miR-122 Serum Level and IFN-λ3 Genotypes in Patients with Chronic HCV and HCV-Infected Liver Transplant Candidate.
    Moayedi J, Hashempour T, Musavi Z, Arefian E, Naderi M, Heidari MR, Dehghani B, Hasanshahi Z, Merat S.

    01/22/2022
    Association between interleukin 28B polymorphism and sustained virological response to sofosbuvir plus daclatasvir in chronic hepatitis C genotype 4 Egyptian patients.

    Association between interleukin 28B polymorphism and sustained virological response to sofosbuvir plus daclatasvir in chronic hepatitis C genotype 4 Egyptian patients.
    Hassanien KS, El-Sayed EM, Ismail RS, Zakarya ZM, Helal GK.

    12/4/2021
    Correlation between IL-28 polymorphism and spontaneous clearance in HCV patients: systematic review and meta-analysis.

    Correlation between IL-28 polymorphism and spontaneous clearance in HCV patients: systematic review and meta-analysis.
    Miri HH, Fazeli P, Ali-Hassanzadeh M, Bemani P, Kabelitz D, Kalantar K.

    10/23/2021
    Interferon-gamma inducible protein-10 and interleukin 28B gene polymorphism as predictive markers for genotype 4 hepatitis C virus treatment response.

    Interferon-γ inducible protein-10 and interleukin 28B gene polymorphism as predictive markers for genotype 4 hepatitis C virus treatment response.
    Abd El-Maksoud E, Salem AM, Maher AM, Hegazy MGA.

    10/16/2021
    Association of IL28 B and IL10 Polymorphism with HCV Infection and Direct Antiviral Treatment.

    Association of IL28 B and IL10 Polymorphism with HCV Infection and Direct Antiviral Treatment.
    Junaid K, Rasool H, Ul Mustafa A, Ejaz H, Alsrhani A, Yasmeen H, Younas S, Abdalla AE, Abdalla Abosalif KO, Mohamed Hamam SS.

    09/11/2021
    [Investigation of the Relationship Between IL28B Polymorphisms and Plasma IL28B Levels in Patients with Chronic Hepatitis B or C].", trans "Kronik Hepatit B veya C Hastalarinda IL28B Polimorfizmleri ve Plazma IL28B Duzeyleri Arasindaki Iliskinin Arastirilmasi.

    [Investigation of the Relationship Between IL28B Polymorphisms and Plasma IL28B Levels in Patients with Chronic Hepatitis B or C].
    Koç Kuralay Z, Tuğ E, Fidan I.

    09/4/2021
    Intrahepatic TLR3 and IFNL3 Expressions Are Associated with Stages of Fibrosis in Chronic Hepatitis C.

    Intrahepatic TLR3 and IFNL3 Expressions Are Associated with Stages of Fibrosis in Chronic Hepatitis C.
    Guedes de Sá KS, Amoras EDSG, Conde SRSDS, Queiroz MAF, Cayres-Vallinoto IMV, Ishak R, Vallinoto ACR., Free PMC Article

    08/21/2021
    Impact of IL28B gene polymorphism on efficacy and safety of direct acting antivirals in hepatitis C Egyptian patients.

    Impact of IL28B gene polymorphism on efficacy and safety of direct acting antivirals in hepatitis C Egyptian patients.
    Ebid AIM, Ahmed OA, Agwa SH, Abdel-Motaleb SM, Hagag RS.

    08/21/2021
    Rotavirus NSP1 Inhibits Type I and Type III Interferon Induction.

    Rotavirus NSP1 Inhibits Type I and Type III Interferon Induction.
    Iaconis G, Jackson B, Childs K, Boyce M, Goodbourn S, Blake N, Iturriza-Gomara M, Seago J., Free PMC Article

    08/14/2021
    Genetic Association of Hepatitis C-Related Mixed Cryoglobulinemia: A 10-Year Prospective Study of Asians Treated with Antivirals.

    Genetic Association of Hepatitis C-Related Mixed Cryoglobulinemia: A 10-Year Prospective Study of Asians Treated with Antivirals.
    Chang ML, Chang SW, Chen SC, Chien RN, Hsu CL, Chang MY, Fann CSJ., Free PMC Article

    08/14/2021
    Multi-ancestry fine mapping of interferon lambda and the outcome of acute hepatitis C virus infection.

    Multi-ancestry fine mapping of interferon lambda and the outcome of acute hepatitis C virus infection.
    Vergara C, Duggal P, Thio CL, Valencia A, O'Brien TR, Latanich R, Timp W, Johnson EO, Kral AH, Mangia A, Goedert JJ, Piazzola V, Mehta SH, Kirk GD, Peters MG, Donfield SM, Edlin BR, Busch MP, Alexander G, Murphy EL, Kim AY, Lauer GM, Chung RT, Cramp ME, Cox AL, Khakoo SI, Rosen HR, Alric L, Wheelan SJ, Wojcik GL, Thomas DL, Taub MA., Free PMC Article

    08/14/2021
    Impact of Interleukin 28B and ICAM-1 Genetic Polymorphisms on Response to Direct Antiviral Treatment Among HCV Infected Patients.

    Impact of Interleukin 28B and ICAM-1 Genetic Polymorphisms on Response to Direct Antiviral Treatment Among HCV Infected Patients.
    Elsheredy AG, Almaeen AH, Ghazy AA, Helaly GF, Amer I, Ghazy HA, Haydara T.

    08/7/2021
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