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    CXCR3 C-X-C motif chemokine receptor 3 [ Homo sapiens (human) ]

    Gene ID: 2833, updated on 22-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The IFN-gamma-CXCL9/CXCL10-CXCR3 axis in vitiligo: Pathological mechanism and treatment.

    The IFN-γ-CXCL9/CXCL10-CXCR3 axis in vitiligo: Pathological mechanism and treatment.
    Liu H, Wang Y, Le Q, Tong J, Wang H.

    04/17/2024
    Hyperactivation of beta-catenin signal in hepatocellular carcinoma recruits myeloid-derived suppressor cells through PF4-CXCR3 axis.

    Hyperactivation of β-catenin signal in hepatocellular carcinoma recruits myeloid-derived suppressor cells through PF4-CXCR3 axis.
    Wang K, Wu J, Yang Z, Zheng B, Shen S, Wang RR, Zhang Y, Wang HY, Chen L, Qiu X.

    03/19/2024
    The CXCL10-CXCR3 axis plays an important role in Kawasaki disease.

    The CXCL10-CXCR3 axis plays an important role in Kawasaki disease.
    Hosaka S, Imagawa K, Yano Y, Lin L, Shiono J, Takahashi-Igari M, Hara H, Hayashi D, Imai H, Morita A, Fukushima H, Takada H.,

    03/13/2024
    CXCL9 and its Receptor CXCR3, an Important Link Between Inflammation and Cardiovascular Risks in RA Patients.

    CXCL9 and its Receptor CXCR3, an Important Link Between Inflammation and Cardiovascular Risks in RA Patients.
    Shamsi A, Roghani SA, Abdan Z, Soufivand P, Pournazari M, Bahrehmand F, Vafaei A, Salari N, Soroush MG, Taghadosi M.

    11/30/2023
    Role of CXCR3 in fibrotic tissue responses.

    Role of CXCR3 in fibrotic tissue responses.
    Wells A.

    11/15/2023
    IL-2/GM-CSF enhances CXCR3 expression in CAR-T cells via the PI3K/AKT and ERK1/2 pathways.

    IL-2/GM-CSF enhances CXCR3 expression in CAR-T cells via the PI3K/AKT and ERK1/2 pathways.
    Liu L, Cheng Y, Zhang F, Chen J, Tian P, Shi W, Zhou F, Yang M, Zhou M, Liu B.

    07/27/2023
    EBV-positive pyothorax-associated lymphoma expresses CXCL9 and CXCL10 chemokines that attract cytotoxic lymphocytes via CXCR3.

    EBV-positive pyothorax-associated lymphoma expresses CXCL9 and CXCL10 chemokines that attract cytotoxic lymphocytes via CXCR3.
    Higuchi T, Hashida Y, Matsuo K, Kitahata K, Ujihara T, Murakami I, Nakayama T, Daibata M., Free PMC Article

    06/7/2023
    Cxcr3 constrains pancreatic cancer dissemination through instructing T cell fate.

    Cxcr3 constrains pancreatic cancer dissemination through instructing T cell fate.
    Burrack AL, Spartz EJ, Rollins MR, Miller EA, Firulyova M, Cruz E, Goldberg MF, Wang IX, Nanda H, Shen S, Zaitsev K, Stromnes IM., Free PMC Article

    05/30/2023
    Clinical Significance of the Pre-Transplant CXCR3 and CCR6 Expression on T Cells In Kidney Graft Recipients.

    Clinical Significance of the Pre-Transplant CXCR3 and CCR6 Expression on T Cells In Kidney Graft Recipients.
    Alfaro R, Llorente S, Gonzalez-Martínez G, Jimenez-Coll V, Martínez-Banaclocha H, Galián JA, Botella C, Moya-Quiles MR, de la Peña-Moral J, Minguela A, Legaz I, Muro M.

    03/15/2023
    Reciprocal expression of the immune response genes CXCR3 and IFI44L as module hubs are associated with patient survivals in primary central nervous system lymphoma.

    Reciprocal expression of the immune response genes CXCR3 and IFI44L as module hubs are associated with patient survivals in primary central nervous system lymphoma.
    Takashima Y, Hamano M, Yoshii K, Hayano A, Fukai J, Iwadate Y, Kajiwara K, Hondoh H, Yamanaka R.

    03/8/2023
    CXCR3 predicts the prognosis of endometrial adenocarcinoma.

    CXCR3 predicts the prognosis of endometrial adenocarcinoma.
    Dong H, Sun M, Li H, Yue Y., Free PMC Article

    02/13/2023
    Relationship between dry eye and expressions of CXCR3 and CCR5 after ocular acid burn.

    Relationship between dry eye and expressions of CXCR3 and CCR5 after ocular acid burn.
    Jiang B, Hu Q, Li T, She M, Li C, Zhou X., Free PMC Article

    12/24/2022
    CXCR3 isoform A promotes head and neck cancer progression by enhancing stem-like property and chemoresistance.

    CXCR3 isoform A promotes head and neck cancer progression by enhancing stem-like property and chemoresistance.
    Sun WH, Peng TJ, Tang SJ, Lin JY, Wang CY, Fang HJ, Sun KH.

    10/22/2022
    Lower CXCR3 expression in both patients with neovascular AMD and advanced stages of chronic myeloproliferative blood cancers.

    Lower CXCR3 expression in both patients with neovascular AMD and advanced stages of chronic myeloproliferative blood cancers.
    Liisborg C, Skov V, Kjær L, Hasselbalch HC, Lykke Sørensen T., Free PMC Article

    06/25/2022
    Chemokine receptor CXCR3 is required for lethal brain pathology but not pathogen clearance during cryptococcal meningoencephalitis.

    Chemokine receptor CXCR3 is required for lethal brain pathology but not pathogen clearance during cryptococcal meningoencephalitis.
    Xu J, Neal LM, Ganguly A, Kolbe JL, Hargarten JC, Elsegeiny W, Hollingsworth C, He X, Ivey M, Lopez R, Zhao J, Segal B, Williamson PR, Olszewski MA., Free PMC Article

    04/23/2022
    TNF-alpha augments CXCL10/CXCR3 axis activity to induce Epithelial-Mesenchymal Transition in colon cancer cell.

    TNF-α augments CXCL10/CXCR3 axis activity to induce Epithelial-Mesenchymal Transition in colon cancer cell.
    Wang Z, Ao X, Shen Z, Ao L, Wu X, Pu C, Guo W, Xing W, He M, Yuan H, Yu J, Li L, Xu X., Free PMC Article

    03/19/2022
    Cxcl10 Chemokine Induces Migration of ING4-Deficient Breast Cancer Cells via a Novel Cross Talk Mechanism between the Cxcr3 and Egfr Receptors.

    Cxcl10 Chemokine Induces Migration of ING4-Deficient Breast Cancer Cells via a Novel Cross Talk Mechanism between the Cxcr3 and Egfr Receptors.
    Tsutsumi E, Stricklin J, Peterson EA, Schroeder JA, Kim S., Free PMC Article

    03/5/2022
    Dual role for CXCR3 and CCR5 in asthmatic type 1 inflammation.

    Dual role for CXCR3 and CCR5 in asthmatic type 1 inflammation.
    Gauthier M, Kale SL, Oriss TB, Scholl K, Das S, Yuan H, Hu S, Chen J, Camiolo M, Ray P, Wenzel S, Ray A., Free PMC Article

    03/5/2022
    Increased Activation of Innate Immunity and Pro-Apoptotic CXCR3B in Normal-Appearing Skin on the Lesional Site of Patients with Segmental Vitiligo.

    Increased Activation of Innate Immunity and Pro-Apoptotic CXCR3B in Normal-Appearing Skin on the Lesional Site of Patients with Segmental Vitiligo.
    Passeron T, Malmqvst VEA, Bzioueche H, Marchetti S, Rocchi S, Tulic MK.

    02/5/2022
    GPR182 limits antitumor immunity via chemokine scavenging in mouse melanoma models.

    GPR182 limits antitumor immunity via chemokine scavenging in mouse melanoma models.
    Torphy RJ, Sun Y, Lin R, Caffrey-Carr A, Fujiwara Y, Ho F, Miller EN, McCarter MD, Lyons TR, Schulick RD, Kedl RM, Zhu Y., Free PMC Article

    01/29/2022
    Role of the CXCR3mediated TLRs/MyD88 signaling pathway in promoting the development of hepatitis B into cirrhosis and liver cancer.

    Role of the CXCR3‑mediated TLRs/MyD88 signaling pathway in promoting the development of hepatitis B into cirrhosis and liver cancer.
    Yuan G, Chen B, Meng Y, Lu J, Shi X, Hu A, Hu Y, Wang D., Free PMC Article

    01/8/2022
    A Regulatory Role of Chemokine Receptor CXCR3 in the Pathogenesis of Chronic Obstructive Pulmonary Disease and Emphysema.

    A Regulatory Role of Chemokine Receptor CXCR3 in the Pathogenesis of Chronic Obstructive Pulmonary Disease and Emphysema.
    Li L, Liu Y, Chiu C, Jin Y, Zhou W, Peng M, Chen LC, Sun Q, Gao J.

    12/11/2021
    Tebentafusp, A TCR/Anti-CD3 Bispecific Fusion Protein Targeting gp100, Potently Activated Antitumor Immune Responses in Patients with Metastatic Melanoma.

    Tebentafusp, A TCR/Anti-CD3 Bispecific Fusion Protein Targeting gp100, Potently Activated Antitumor Immune Responses in Patients with Metastatic Melanoma.
    Middleton MR, McAlpine C, Woodcock VK, Corrie P, Infante JR, Steven NM, Evans TRJ, Anthoney A, Shoushtari AN, Hamid O, Gupta A, Vardeu A, Leach E, Naidoo R, Stanhope S, Lewis S, Hurst J, O'Kelly I, Sznol M., Free PMC Article

    11/27/2021
    CXCR3 and Cognate Ligands are Associated with Immune Cell Alteration and Aggressiveness of Pancreatic Ductal Adenocarcinoma.

    CXCR3 and Cognate Ligands are Associated with Immune Cell Alteration and Aggressiveness of Pancreatic Ductal Adenocarcinoma.
    Cannon A, Thompson CM, Maurer HC, Atri P, Bhatia R, West S, Ghersi D, Olive KP, Kumar S, Batra SK., Free PMC Article

    11/27/2021
    Both T cell priming in lymph node and CXCR3-dependent migration are the key events for predicting the response of atezolizumab.

    Both T cell priming in lymph node and CXCR3-dependent migration are the key events for predicting the response of atezolizumab.
    Iwai T, Sugimoto M, Patil NS, Bower D, Suzuki M, Kato C, Yorozu K, Kurasawa M, Shames DS, Kondoh O., Free PMC Article

    11/6/2021
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