| Association of Glutathione Transferase M1, T1, P1 and A1 Gene Polymorphism and Susceptibility to IgA Vasculitis. | Association of Glutathione Transferase M1, T1, P1 and A1 Gene Polymorphism and Susceptibility to IgA Vasculitis.
Juras A, Crkvenac Gornik K, Held M, Sestan M, Turudic D, Sapina M, Srsen S, Huljev Frkovic S, Frkovic M, Gagro A, Jelusic M., Free PMC Article | 08/13/2024 |
| Genomic investigation on genes related to mercury metabolism in Amazonian indigenous populations. | Genomic investigation on genes related to mercury metabolism in Amazonian indigenous populations.
Carvalho VHV, Rodrigues JCG, Vinagre LWMS, Pereira EEB, Monte N, Fernandes MR, Ribeiro-Dos-Santos AM, Guerreiro JF, Ribeiro-Dos-Santos Â, Dos Santos SEB, Dos Santos NPC. | 06/10/2024 |
| Influence of Glutathione-S-Transferase A1*B Allele on the Metabolism of the Aromatase Inhibitor, Exemestane, in Human Liver Cytosols and in Patients Treated With Exemestane. | Influence of Glutathione-S-Transferase A1*B Allele on the Metabolism of the Aromatase Inhibitor, Exemestane, in Human Liver Cytosols and in Patients Treated With Exemestane.
Teslenko I, Trudeau J, Luo S, Watson CJW, Chen G, Truica CI, Lazarus P., Free PMC Article | 09/3/2022 |
| The analysis of GSTA1 promoter genetic and functional diversity of human populations. | The analysis of GSTA1 promoter genetic and functional diversity of human populations.
Mlakar V, Curtis PH, Armengol M, Ythier V, Dupanloup I, Hassine KB, Lesne L, Murr R, Mlakar SJ, Nava T, Ansari M., Free PMC Article | 12/18/2021 |
| Comparison of the tissue expressions of glutathione S transferase isoenzymes among patients with morphea and healthy controls: A preliminary study. | Comparison of the tissue expressions of glutathione S transferase isoenzymes among patients with morphea and healthy controls: A preliminary study.
Uzuncakmak TK, Koska MC, Ozkanli S, Kaya Kocdogan A, Oguztuzun S, Karadag AS, Akdeniz N, Wollina U. | 08/21/2021 |
| The Interaction of Human Glutathione Transferase GSTA1-1 with Reactive Dyes. | The Interaction of Human Glutathione Transferase GSTA1-1 with Reactive Dyes.
Alqarni MH, Foudah AI, Muharram MM, Labrou NE., Free PMC Article | 05/22/2021 |
| Population pharmacokinetic analysis of intravenous busulfan: GSTA1 genotype is not a predictive factor of initial dose in Chinese adult patients undergoing hematopoietic stem cell transplantation. | Population pharmacokinetic analysis of intravenous busulfan: GSTA1 genotype is not a predictive factor of initial dose in Chinese adult patients undergoing hematopoietic stem cell transplantation.
Sun Y, Huang J, Hao C, Li Z, Liang W, Zhang W, Chen B, Yang W, Hu J. | 08/15/2020 |
| GSTA1, GSTM1, and GSTT1 polymorphisms in patients undergoing hematopoietic stem cell transplantation may have affected busulfan pharmacokinetics, but these effects were obscured by other factors, such as underlying disease, systemic conditions, treatment history, and race. | Influence of GST polymorphisms on busulfan pharmacokinetics in Japanese children.
Nishikawa T, Yamaguchi H, Ikawa K, Nakayama K, Higashi E, Miyahara E, Abematsu T, Nakagawa S, Kodama Y, Tanabe T, Shigemi A, Shinkoda Y, Okamoto Y, Takeda Y, Kawano Y. | 01/4/2020 |
| Genotypes with lower or null activity of the GSTA1, GSTM1 or GSTT1 did not contribute independently to psoriasis susceptibility in our patients. However, we observed significant associations of genotype combinations with the risk of psoriasis development. | Combinations of common polymorphisms within GSTA1 and GSTT1 as a risk factor for psoriasis in a central European population: a case-control study.
Hruska P, Rybecka S, Novak J, Zlamal F, Splichal Z, Slaby O, Vasku V, Bienertova-Vasku J. | 07/6/2019 |
| For glutathione S-transferase alpha 1(GSTA1) and glutathione S-transferase mu 1(GSTM1) polymorphisms, an association was observed with dietary fiber intake | Association of Glutathione S-Transferase Polymorphisms with Dietary Composition but Not Anthropometry in Obese as Well as Nonobese Individuals.
Klánová B, Zlámal F, Pohořalá A, Slabý O, Pikhart H, Bienertová-Vašků J. | 03/30/2019 |
| With the use of siRNAs to compare the roles of GSTP1, GSTM2 and GSTA1 in three representative cisplatinresistant solid cancer cells, it is preliminarily concluded that GSTA predominates over the other two isozymes in the cisplatin resistance of the tested lungs, ovaries and stomach cancer cells. | Glutathione S‑transferase isozyme alpha 1 is predominantly involved in the cisplatin resistance of common types of solid cancer.
Zou M, Hu X, Xu B, Tong T, Jing Y, Xi L, Zhou W, Lu J, Wang X, Yang X, Liao F. | 02/9/2019 |
| GSTA1 Expression Is Correlated With Aldosterone Level in KCNJ5-Mutated Adrenal Aldosterone-Producing Adenoma. | GSTA1 Expression Is Correlated With Aldosterone Level in KCNJ5-Mutated Adrenal Aldosterone-Producing Adenoma.
Li X, Wang B, Tang L, Zhang Y, Chen L, Gu L, Zhang F, Ouyang J, Zhang X. | 06/9/2018 |
| Data (including data from studies using single-molecule fluorescence imaging) suggest that, for GSTA1, there are at least two conformations of the protein, consistent with model that ligand binding promotes closure of carboxy-terminal helix over active site; study involved binding of glutathione analogs and enzyme inhibitors. | Dual Lifetimes for Complexes between Glutathione-S-transferase (hGSTA1-1) and Product-like Ligands Detected by Single-Molecule Fluorescence Imaging.
Pettersson JR, Lanni F, Rule GS. | 08/19/2017 |
| Combined GSTM1, GSTT1, GSTA1 and GSTP1 polymorphisms might be associated to the risk of clear cell renal cell carcinoma. | Combined GSTM1-Null, GSTT1-Active, GSTA1 Low-Activity and GSTP1-Variant Genotype Is Associated with Increased Risk of Clear Cell Renal Cell Carcinoma.
Coric VM, Simic TP, Pekmezovic TD, Basta-Jovanovic GM, Savic Radojevic AR, Radojevic-Skodric SM, Matic MG, Dragicevic DP, Radic TM, Bogdanovic LM, Dzamic ZM, Pljesa-Ercegovac MS., Free PMC Article | 08/5/2017 |
| Data show that the glutathione S-transferase alpha 1(GSTA1) TT genotype was more frequent in hepatocellular carcinoma (HCC) than in non-HCC patients, suggesting that individuals carrying this genotype could be associated with 2-fold higher risk of developing HCCs. | The rs3957357C>T SNP in GSTA1 Is Associated with a Higher Risk of Occurrence of Hepatocellular Carcinoma in European Individuals.
Akhdar H, El Shamieh S, Musso O, Désert R, Joumaa W, Guyader D, Aninat C, Corlu A, Morel F., Free PMC Article | 07/29/2017 |
| Nrf-2 and Gst-a were more abundant in bone morrow of chronic myeloid leukemia(CML) patients compared with that of healthy donors. In addition, Nrf-2 and Gst-a were further up-regulated in samples of patients with weak response to IM. In conclusion, our study shows that rapid clearance of 4-HNE by Nrf-2/GST may represents a novel molecular basis of IM resistance in CML. | Nrf-2/Gst-α mediated imatinib resistance through rapid 4-HNE clearance.
Wang X, Li Y, Chen W, Wang Y, Hui L, Liu J, Li N, Zhang L, Zou Y, Wang F. | 05/27/2017 |
| Study found an association, although not statistically significant between GSTA1 gene variants and perioperative serum alpha-GST level, an indicator for liver hepatotoxicity. | Impact of CYP2E1, GSTA1 and GSTP1 gene variants on serum alpha glutathione S-transferase level in patients undergoing anaesthesia.
Mikstacki A, Skrzypczak-Zielinska M, Zakerska-Banaszak O, Tamowicz B, Skibinska M, Molinska-Glura M, Szalata M, Slomski R., Free PMC Article | 05/6/2017 |
| common polymorphisms in GSTA1, GSTM1 and GSTT1 are associated with susceptibility to bladder cancer in individuals from Balkan endemic nephropathy areas of Serbia. | Common Polymorphisms in GSTA1, GSTM1 and GSTT1 Are Associated with Susceptibility to Urinary Bladder Cancer in Individuals from Balkan Endemic Nephropathy Areas of Serbia.
Matic M, Dragicevic B, Pekmezovic T, Suvakov S, Savic-Radojevic A, Pljesa-Ercegovac M, Dragicevic D, Smiljic J, Simic T. | 04/1/2017 |
| Data show that a higher concentration of fluoride in the saliva was detected in children with a higher glutathione S-transferase (GST) activity. | Enzymatic Activity of Glutathione S-Transferase and Dental Fluorosis Among Children Receiving Two Different Levels of Naturally Fluoridated Water.
Bonola-Gallardo I, Irigoyen-Camacho ME, Vera-Robles L, Campero A, Gómez-Quiroz L. | 03/4/2017 |
| polymorphisms not associated with bladder cancer susceptibility [meta-analysis] | The relationship between GSTA1, GSTM1, GSTP1, and GSTT1 genetic polymorphisms and bladder cancer susceptibility: A meta-analysis.
Yu Y, Li X, Liang C, Tang J, Qin Z, Wang C, Xu W, Hua Y, Shao P, Xu T., Free PMC Article | 02/18/2017 |
| Influence of glutathione S-transferase gene polymorphisms on busulfan pharmacokinetics and outcome of hematopoietic stem-cell transplantation in thalassemia pediatric patients. | Influence of glutathione S-transferase gene polymorphisms on busulfan pharmacokinetics and outcome of hematopoietic stem-cell transplantation in thalassemia pediatric patients.
Ansari M, Huezo-Diaz P, Rezgui MA, Marktel S, Duval M, Bittencourt H, Cappelli B, Krajinovic M., Free PMC Article | 12/17/2016 |
| The frequency of GSTA1, GSTM1 and GSTP1 genotypes was not significantly different between progressive myoclonus epilepsy patients and controls | GSTA1, GSTM1, GSTP1 and GSTT1 polymorphisms in progressive myoclonus epilepsy: A Serbian case-control study.
Ercegovac M, Jovic N, Sokic D, Savic-Radojevic A, Coric V, Radic T, Nikolic D, Kecmanovic M, Matic M, Simic T, Pljesa-Ercegovac M. | 08/20/2016 |
| GSTA1 polymorphism is associated with different pregnancy-related conditions | GSTA1 gene variation associated with gestational hypertension and its involvement in pregnancy-related pathogenic conditions.
Iorio A, Spinelli M, Polimanti R, Lorenzi F, Valensise H, Manfellotto D, Fuciarelli M. | 08/13/2016 |
| this is the first population pharmacokinetic study to suggest that GSTA1 polymorphisms in adults are associated with busulfan pharmacokinetics | Population pharmacokinetics and pharmacodynamics of busulfan with GSTA1 polymorphisms in patients undergoing allogeneic hematopoietic stem cell transplantation.
Choi B, Kim MG, Han N, Kim T, Ji E, Park S, Kim IW, Oh JM. | 07/30/2016 |
| GST genotyping before hematopoietic stem cell transplantation may allow better prediction of busulfan pharmacokinetics and drug toxicity, and thereby improve outcome after busulfan and cyclophosphamide conditioning | Glutathione Transferase Gene Variants Influence Busulfan Pharmacokinetics and Outcome After Myeloablative Conditioning.
Bremer S, Fløisand Y, Brinch L, Gedde-Dahl T, Bergan S., Free PMC Article | 05/14/2016 |