| The Biological Implication of Semicarbazide-Sensitive Amine Oxidase (SSAO) Upregulation in Rat Systemic Inflammatory Response under Simulated Aerospace Environment. | The Biological Implication of Semicarbazide-Sensitive Amine Oxidase (SSAO) Upregulation in Rat Systemic Inflammatory Response under Simulated Aerospace Environment.
Yan L, Sun C, Zhang Y, Zhang P, Chen Y, Deng Y, Er T, Deng Y, Wang Z, Ma H., Free PMC Article | 03/22/2023 |
| Comparison of Inhibitor and Substrate Selectivity between Rodent and Human Vascular Adhesion Protein-1. | Comparison of Inhibitor and Substrate Selectivity between Rodent and Human Vascular Adhesion Protein-1.
Kubota R, Reid MJ, Lieu KL, Orme M, Diamond C, Tulberg N, Henry SH., Free PMC Article | 07/10/2021 |
| In acute mesenteric ischemia, Vap-1 levels are significantly increased and correlated with ischemic changes. | Comparison of the diagnostic values of vascular adhesion protein-1 and intestinal fatty acid-binding protein in the diagnosis of acute mesenteric ischemia.
Sahin A, Altay DA, Demir S, Yulug E, Menteşe A, Tatli O, Karaca Y, Ardic S, Gunduz A, Turedi S. | 01/4/2020 |
| Data show that 35 potential amine oxidase copper containing 3 (SSAO)-interacting proteins were found to be altered in type 2 Diabetes (T2D). | Alteration of SSAO interactome reveals weakened cell adhesion and motor function of adipocytes in T2D.
Ke M, Zhang Y, Deng Y. | 08/18/2018 |
| VAP-1 plays a critical role in the pathophysiology of renal ischemia/reperfusion injury by enhancement of neutrophil infiltration generating a local hydrogen peroxide gradient. | Vascular adhesion protein-1 enhances neutrophil infiltration by generation of hydrogen peroxide in renal ischemia/reperfusion injury.
Tanaka S, Tanaka T, Kawakami T, Takano H, Sugahara M, Saito H, Higashijima Y, Yamaguchi J, Inagi R, Nangaku M. | 04/7/2018 |
| The changes of K(M) and k(c)/K(M) values of copper amine oxidase appear due to the presence of positively charged groups in the substrate molecules. | Preliminary kinetic characterization of a copper amine oxidase from rat liver mitochondria matrix.
Stevanato R, Cardillo S, Braga M, De Iuliis A, Battaglia V, Toninello A, Agostinelli E, Vianello F. | 05/28/2011 |
| Provide evidence for a role for VAP-1 in the inflammatory outcome of diabetic retinopathy. Specifically, VAP-1 plays a central role in regulating leukocyte transmigration rate during chronic low-grade inflammation. | Vascular adhesion protein-1 regulates leukocyte transmigration rate in the retina during diabetes.
Noda K, Nakao S, Zandi S, Engelstädter V, Mashima Y, Hafezi-Moghadam A., Free PMC Article | 02/8/2010 |
| evidence for an important role of VAP-1 in the recruitment of macrophages to choroidal neovascularization lesions, establishing a novel link between VAP-1 and angiogenesis | Vascular adhesion protein-1 blockade suppresses choroidal neovascularization.
Noda K, She H, Nakazawa T, Hisatomi T, Nakao S, Almulki L, Zandi S, Miyahara S, Ito Y, Thomas KL, Garland RC, Miller JW, Gragoudas ES, Mashima Y, Hafezi-Moghadam A., Free PMC Article | 01/21/2010 |
| It was concluded that hydroxylamine exerts hypotension partly through conversion to nitric oxide and partly by a "hydralazine-like" mechanism involving SSAO inhibition | Hypotensive effect of hydroxylamine, an endogenous nitric oxide donor and SSAO inhibitor.
Vidrio H, Medina M. | 01/21/2010 |
| BZA + V treatment did not reduce HbA(1C) levels,but it reduced the elevated serum SSAO activity, decreased advanced-glycation end products and increased nitric oxide in diabetic animals. | Studies on the insulinomimetic effects of benzylamine, exogenous substrate of semicarbazide-sensitive amine oxidase enzyme in streptozotocin induced diabetic rats.
Soltész Z, Tábi T, Halász AS, Pálfi M, Kocsis E, Magyar K, Tóth M, Szökö E. | 01/21/2010 |
| Our parsimonious conclusion is that there is a relation between the risk factors of AD and vascular dementia (diabetes, oxidative stress and chronic inflammation) and SSAO activity, which may originate from the vessel wall. | Soluble semicarbazide-sensitive amine oxidase (SSAO) activity is related to oxidative stress and subchronic inflammation in streptozotocin-induced diabetic rats.
Somfai GM, Knippel B, Ruzicska E, Stadler K, Tóth M, Salacz G, Magyar K, Somogyi A. | 01/21/2010 |
| Enzymatic activity of the atypical endothelial adhesion molecule AOC3, and possibly that of other related oxidases, is crucial for leukocyte exit from the vessels in inflamed joints in vivo. | Vascular amine oxidases are needed for leukocyte extravasation into inflamed joints in vivo.
Marttila-Ichihara F, Smith DJ, Stolen C, Yegutkin GG, Elima K, Mercier N, Kiviranta R, Pihlavisto M, Alaranta S, Pentikäinen U, Pentikäinen O, Fülöp F, Jalkanen S, Salmi M. | 01/21/2010 |