| A1CF Binding to the p65 Interaction Site on NKRF Decreased IFN-beta Expression and p65 Phosphorylation (Ser536) in Renal Carcinoma Cells. | A1CF Binding to the p65 Interaction Site on NKRF Decreased IFN-β Expression and p65 Phosphorylation (Ser536) in Renal Carcinoma Cells.
Liu Y, Yang J, Weng D, Xie Y., Free PMC Article | 04/17/2024 |
| High APOBEC1 Complementation Factor Expression Positively Modulates the Proliferation, Invasion, and Migration of Endometrial Cancer Cells Through Regulating P53/P21 Signaling Pathway. | High APOBEC1 Complementation Factor Expression Positively Modulates the Proliferation, Invasion, and Migration of Endometrial Cancer Cells Through Regulating P53/P21 Signaling Pathway.
Liu Q, Chen CY, Chen GL. | 11/26/2022 |
| Both variants of A1CF and BAZ1B genes are associated with gout susceptibility: a replication study and meta-analysis in a Japanese population. | Both variants of A1CF and BAZ1B genes are associated with gout susceptibility: a replication study and meta-analysis in a Japanese population.
Kawaguchi M, Nakayama A, Aoyagi Y, Nakamura T, Shimizu S, Kawamura Y, Takao M, Tamura T, Hishida A, Nagayoshi M, Nagase M, Ooyama K, Ooyama H, Shinomiya N, Matsuo H., Free PMC Article | 08/7/2021 |
| this study revealed that A1CF can upregulate the expression of FAM224A via strengthening its stability, which in turn, influenced the negative modulation of miR-590-3p on transcription factor ZNF143. | Inhibition of the aberrant A1CF-FAM224A-miR-590-3p-ZNF143 positive feedback loop attenuated malignant biological behaviors of glioma cells.
Song Y, Shao L, Xue Y, Ruan X, Liu X, Yang C, Zheng J, Shen S, Chen J, Li Z, Liu Y., Free PMC Article | 12/7/2019 |
| A1CF-Axin2 signal axis regulates Wilms tumor-derived cells' apoptosis and migration through Axin2. | A1CF-Axin2 signal axis regulates apoptosis and migration in Wilms tumor-derived cells through Wnt/β-catenin pathway.
Ni D, Liu J, Hu Y, Liu Y, Gu Y, Zhou Q, Xie Y. | 07/20/2019 |
| Interaction of any alcohol exposure with GCKR (rs780094) and A1CF (rs10821905) influenced the risk of gout in Europeans | Interaction of the GCKR and A1CF loci with alcohol consumption to influence the risk of gout.
Rasheed H, Stamp LK, Dalbeth N, Merriman TR., Free PMC Article | 04/21/2018 |
| Study reported that the deleted 8aa, EIYMNVPV, was just localized in the internal region of A1CF nuclear translocation signal. Also, A1CF (-8aa), but not its full-length counterpart, can promote proliferation of MDA-MB-231 cells accompanied with increased level of IL-6 mRNA. | EIYMNVPV Motif is Essential for A1CF Nucleus Localization and A1CF (-8aa) Promotes Proliferation of MDA-MB-231 Cells via Up-Regulation of IL-6.
Zhou L, Hao J, Yuan Y, Peng R, Wang H, Ni D, Gu Y, Huang L, Mao Z, Lyu Z, Du Y, Liu Z, Li Y, Ju P, Long Y, Liu J, Zhou Q., Free PMC Article | 03/18/2017 |
| hnRNP K and hnRNP L may serve as A1CF-like cofactors in AID-mediated class switch recombination and somatic hypermutation | Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase.
Hu W, Begum NA, Mondal S, Stanlie A, Honjo T., Free PMC Article | 08/8/2015 |
| The data presented in this report suggested that similar regulatory mechanisms controlling the functional interaction of APOBEC-1 with ACF might be operational during enterocyte differentiation. | The expression of apoB mRNA editing factors is not the sole determinant for the induction of editing in differentiating Caco-2 cells.
Galloway CA, Smith HC., Free PMC Article | 03/22/2010 |
| results suggested both AID and APOBEC-1 are equally likely to bind single-stranded DNA or RNA, which has implications for the identification of natural AID targets | The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1.
Xie K, Sowden MP, Dance GS, Torelli AT, Smith HC, Wedekind JE., Free PMC Article | 01/21/2010 |
| ACF plays a crucial role, which is independent of apobec-1 expression, in cell survival, particularly during early embryonic development | Targeted deletion of the murine apobec-1 complementation factor (acf) gene results in embryonic lethality.
Blanc V, Henderson JO, Newberry EP, Kennedy S, Luo J, Davidson NO., Free PMC Article | 01/21/2010 |