| Elevated expression of LCN13 through FXR activation ameliorates hepatocellular lipid accumulation and inflammation. | Elevated expression of LCN13 through FXR activation ameliorates hepatocellular lipid accumulation and inflammation.
Qin X, Tan Y, Ren W, Zhou W, Niu R, Liang L, Li J, Cao K, Wei G, Zhu X, Huang M. | 04/22/2024 |
| Tumor-derived OBP2A promotes prostate cancer castration resistance. | Tumor-derived OBP2A promotes prostate cancer castration resistance.
Jeong JH, Zhong S, Li F, Huang C, Chen X, Liu Q, Peng S, Park H, Lee YM, Dhillon J, Luo JL., Free PMC Article | 01/14/2023 |
| A polymorphism in the human gene encoding OBPIIa affects the perceived intensity of smelled odors. | A polymorphism in the human gene encoding OBPIIa affects the perceived intensity of smelled odors.
Sollai G, Melis M, Tomassini Barbarossa I, Crnjar R. | 04/30/2022 |
| Effect of the rs2890498 polymorphism of the OBPIIa gene on the human ability to smell single molecules. | Effect of the rs2890498 polymorphism of the OBPIIa gene on the human ability to smell single molecules.
Melis M, Tomassini Barbarossa I, Hummel T, Crnjar R, Sollai G. | 01/1/2022 |
| Changes of Taste, Smell and Eating Behavior in Patients Undergoing Bariatric Surgery: Associations with PROP Phenotypes and Polymorphisms in the Odorant-Binding Protein OBPIIa and CD36 Receptor Genes. | Changes of Taste, Smell and Eating Behavior in Patients Undergoing Bariatric Surgery: Associations with PROP Phenotypes and Polymorphisms in the Odorant-Binding Protein OBPIIa and CD36 Receptor Genes.
Melis M, Pintus S, Mastinu M, Fantola G, Moroni R, Pepino MY, Barbarossa IT., Free PMC Article | 09/11/2021 |
| Olfactory Function in Patients with Inflammatory Bowel Disease (IBD) Is Associated with Their Body Mass Index and Polymorphism in the Odor Binding-Protein (OBPIIa) Gene. | Olfactory Function in Patients with Inflammatory Bowel Disease (IBD) Is Associated with Their Body Mass Index and Polymorphism in the Odor Binding-Protein (OBPIIa) Gene.
Sollai G, Melis M, Mastinu M, Paduano D, Chicco F, Magri S, Usai P, Hummel T, Barbarossa IT, Crnjar R., Free PMC Article | 08/21/2021 |
| Importantly, OBPIIa gene polymorphism showed an effect on Parkinson's disease-related olfactory deficits only in women. | Odor Identification Performance in Idiopathic Parkinson's Disease Is Associated With Gender and the Genetic Variability of the Olfactory Binding Protein.
Melis M, Sollai G, Masala C, Pisanu C, Cossu G, Melis M, Sarchioto M, Oppo V, Morelli M, Crnjar R, Hummel T, Tomassini Barbarossa I. | 10/3/2020 |
| Association between the rs2590498 polymorphism of Odorant Binding Protein (OBPIIa) gene and olfactory performance in healthy subjects. | Association between the rs2590498 polymorphism of Odorant Binding Protein (OBPIIa) gene and olfactory performance in healthy subjects.
Sollai G, Melis M, Magri S, Usai P, Hummel T, Tomassini Barbarossa I, Crnjar R. | 09/12/2020 |
| This study demonstrated that the OBPIIa is associated with bitter sensitivity in human. | Variant in a common odorant-binding protein gene is associated with bitter sensitivity in people.
Tomassini Barbarossa I, Ozdener MH, Melania, Love-Gregory L, Mitreva M, Abumrad NA, Pepino MY., Free PMC Article | 03/17/2018 |
| Studied the crystallographic structure of human odorant-binding protein, OBPIIa at 2.6 A resolution. | Crystal structure of the human odorant binding protein, OBPIIa.
Schiefner A, Freier R, Eichinger A, Skerra A. | 02/6/2016 |
| Lys112 is the major determinant for governing hOBP-2A specificity towards aldehydes and small carboxylic acids. | A single lysyl residue defines the binding specificity of a human odorant-binding protein for aldehydes.
Tcatchoff L, Nespoulous C, Pernollet JC, Briand L. | 01/21/2010 |
| hOBPIIa(alpha) is expressed in the nasal mucus covering the olfactory cleft and is able to bind numerous odorants of diverse chemical structures, with a higher affinity for aldehydes and large fatty acids. | Evidence of an odorant-binding protein in the human olfactory mucus: location, structural characterization, and odorant-binding properties.
Briand L, Eloit C, Nespoulous C, Bézirard V, Huet JC, Henry C, Blon F, Trotier D, Pernollet JC. | 01/21/2010 |