U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    H2AX H2A.X variant histone [ Homo sapiens (human) ]

    Gene ID: 3014, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Overexpression of H2AFX gene in neuroblastoma is associated with worse prognosis.

    Overexpression of H2AFX gene in neuroblastoma is associated with worse prognosis.
    Ognibene M, Parodi S, Amoroso L, Zara F, Pezzolo A.

    07/29/2024
    H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours.

    H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours.
    Dibitetto D, Liptay M, Vivalda F, Dogan H, Gogola E, González Fernández M, Duarte A, Schmid JA, Decollogny M, Francica P, Przetocka S, Durant ST, Forment JV, Klebic I, Siffert M, de Bruijn R, Kousholt AN, Marti NA, Dettwiler M, Sørensen CS, Tille JC, Undurraga M, Labidi-Galy I, Lopes M, Sartori AA, Jonkers J, Rottenberg S., Free PMC Article

    06/11/2024
    Hypoxia-responsive lncRNA G077640 promotes ESCC tumorigenesis via the H2AX-HIF1alpha-glycolysis axis.

    Hypoxia-responsive lncRNA G077640 promotes ESCC tumorigenesis via the H2AX-HIF1α-glycolysis axis.
    Huang X, Liu C, Li H, Dai T, Luo G, Zhang C, Li T, Lü M.

    08/22/2023
    Machine learning extracts oncogenic-specific gamma-H2AX foci formation pattern upon genotoxic stress.

    Machine learning extracts oncogenic-specific γ-H2AX foci formation pattern upon genotoxic stress.
    Furuya K, Ikura M, Ikura T.

    03/16/2023
    USP49 is a novel deubiquitylating enzyme for gamma H2AX in DNA double-strand break repair.

    USP49 is a novel deubiquitylating enzyme for γ H2AX in DNA double-strand break repair.
    Matsui M, Kajita S, Tsuchiya Y, Torii W, Tamekuni S, Nishi R.

    07/2/2022
    Genetic variations in ATM and H2AX loci contribute to risk of hematological abnormalities in individuals exposed to BTEX chemicals.

    Genetic variations in ATM and H2AX loci contribute to risk of hematological abnormalities in individuals exposed to BTEX chemicals.
    Jafari Roshan S, Mansoori Y, Hosseini SR, Sabour D, Daraei A., Free PMC Article

    04/23/2022
    Pyruvate Facilitates FACT-Mediated gammaH2AX Loading to Chromatin and Promotes the Radiation Resistance of Glioblastoma.

    Pyruvate Facilitates FACT-Mediated γH2AX Loading to Chromatin and Promotes the Radiation Resistance of Glioblastoma.
    Wu S, Cao R, Tao B, Wu P, Peng C, Gao H, Liang J, Yang W., Free PMC Article

    04/16/2022
    Phosphorylation state of the histone variant H2A.X controls human stem and progenitor cell fate decisions.

    Phosphorylation state of the histone variant H2A.X controls human stem and progenitor cell fate decisions.
    Orlando L, Tanasijevic B, Nakanishi M, Reid JC, García-Rodríguez JL, Chauhan KD, Porras DP, Aslostovar L, Lu JD, Shapovalova Z, Mitchell RR, Boyd AL, Bhatia M.

    03/19/2022
    Cleavage-embryo genes and transposable elements are regulated by histone variant H2A.X.

    Cleavage-embryo genes and transposable elements are regulated by histone variant H2A.X.
    Sun KY, Guo SM, Cheng GP, Yin Y, He X, Zhou LQ., Free PMC Article

    02/12/2022
    Human mesenchymal stromal cells maintain their stem cell traits after high-LET particle irradiation - Potential implications for particle radiotherapy and manned space missions.

    Human mesenchymal stromal cells maintain their stem cell traits after high-LET particle irradiation - Potential implications for particle radiotherapy and manned space missions.
    Rühle A, Ping D, Lopez Perez R, Strack M, Brons S, Yijia Q, Debus J, Wuchter P, Grosu AL, Huber PE, Nicolay NH.

    01/8/2022
    Dysfunctional activity of classical DNA end-joining renders acquired resistance to carboplatin in human ovarian cancer cells.

    Dysfunctional activity of classical DNA end-joining renders acquired resistance to carboplatin in human ovarian cancer cells.
    Yoon MJ, Cha H, Ahn J, Lee D, Jeong HS, Koo HS, Kang YJ.

    01/8/2022
    Detection and quantification of gamma-H2AX using a dissociation enhanced lanthanide fluorescence immunoassay.

    Detection and quantification of γ-H2AX using a dissociation enhanced lanthanide fluorescence immunoassay.
    Noubissi FK, McBride AA, Leppert HG, Millet LJ, Wang X, Davern SM., Free PMC Article

    11/13/2021
    FLYWCH1, a Multi-Functional Zinc Finger Protein Contributes to the DNA Repair Pathway.

    FLYWCH1, a Multi-Functional Zinc Finger Protein Contributes to the DNA Repair Pathway.
    Almozyan S, Coulton J, Babaei-Jadidi R, Nateri AS., Free PMC Article

    10/23/2021
    Sarcoma stratification by combined pH2AX and MAP17 (PDZK1IP1) levels for a better outcome on doxorubicin plus olaparib treatment.

    Sarcoma stratification by combined pH2AX and MAP17 (PDZK1IP1) levels for a better outcome on doxorubicin plus olaparib treatment.
    Perez M, García-Heredia JM, Felipe-Abrio B, Muñoz-Galván S, Martín-Broto J, Carnero A., Free PMC Article

    10/16/2021
    Evaluation of Calyculin A Effect on gammaH2AX/53BP1 Focus Formation and Apoptosis in Human Umbilical Cord Blood Lymphocytes.

    Evaluation of Calyculin A Effect on γH2AX/53BP1 Focus Formation and Apoptosis in Human Umbilical Cord Blood Lymphocytes.
    Zastko L, Račková A, Petrovičová P, Durdík M, Míšek J, Marková E, Belyaev I., Free PMC Article

    06/19/2021
    Profilin-1; a novel regulator of DNA damage response and repair machinery in keratinocytes.

    Profilin-1; a novel regulator of DNA damage response and repair machinery in keratinocytes.
    Lee CJ, Yoon MJ, Kim DH, Kim TU, Kang YJ., Free PMC Article

    05/22/2021
    Evaluating Individual Radiosensitivity for the Prediction of Acute Toxicities of Chemoradiotherapy in Esophageal Cancer Patients.

    Evaluating Individual Radiosensitivity for the Prediction of Acute Toxicities of Chemoradiotherapy in Esophageal Cancer Patients.
    Imano N, Nishibuchi I, Kawabata E, Kinugasa Y, Shi L, Sakai C, Ishida M, Sakane H, Akita T, Ishida T, Kimura T, Murakami Y, Tanaka K, Horikoshi Y, Sun J, Nagata Y, Tashiro S.

    05/1/2021
    ADP-ribosylation of histone variant H2AX promotes base excision repair.

    ADP-ribosylation of histone variant H2AX promotes base excision repair.
    Chen Q, Bian C, Wang X, Liu X, Ahmad Kassab M, Yu Y, Yu X., Free PMC Article

    04/24/2021
    DNA damage signalling as an anti-cancer barrier in gastric intestinal metaplasia.

    DNA damage signalling as an anti-cancer barrier in gastric intestinal metaplasia.
    Krishnan V, Lim DXE, Hoang PM, Srivastava S, Matsuo J, Huang KK, Zhu F, Ho KY, So JBY, Khor C, Tsao S, Teh M, Fock KM, Ang TL, Jeyasekharan AD, Tan P, Yeoh KG, Ito Y., Free PMC Article

    04/13/2021
    Changes in gammaH2AX and H4K16ac levels are involved in the biochemical response to a competitive soccer match in adolescent players.

    Changes in γH2AX and H4K16ac levels are involved in the biochemical response to a competitive soccer match in adolescent players.
    Kozioł K, Zebrowski J, Betlej G, Bator E, Czarny W, Bajorek W, Czarnota B, Czaja R, Król P, Kwiatkowska A., Free PMC Article

    03/6/2021
    Dual RNA 3'-end processing of H2A.X messenger RNA maintains DNA damage repair throughout the cell cycle.

    Dual RNA 3'-end processing of H2A.X messenger RNA maintains DNA damage repair throughout the cell cycle.
    Griesbach E, Schlackow M, Marzluff WF, Proudfoot NJ., Free PMC Article

    02/6/2021
    In vivo analysis of gammaH2AX+ cells in skeletal muscle from aged and obese humans.

    In vivo analysis of γH2AX+ cells in skeletal muscle from aged and obese humans.
    Dungan CM, Peck BD, Walton RG, Huang Z, Bamman MM, Kern PA, Peterson CA., Free PMC Article

    02/2/2021
    The RNA transport factor PHAX is required for proper histone H2AX expression and DNA damage response.

    The RNA transport factor PHAX is required for proper histone H2AX expression and DNA damage response.
    Machitani M, Taniguchi I, McCloskey A, Suzuki T, Ohno M., Free PMC Article

    01/23/2021
    Unscheduled MRE11 activity triggers cell death but not chromosome instability in polymerase eta-depleted cells subjected to UV irradiation.

    Unscheduled MRE11 activity triggers cell death but not chromosome instability in polymerase eta-depleted cells subjected to UV irradiation.
    Federico MB, Siri SO, Calzetta NL, Paviolo NS, de la Vega MB, Martino J, Campana MC, Wiesmüller L, Gottifredi V.

    11/28/2020
    Repurposing sodium diclofenac as a radiation countermeasure agent: A cytogenetic study in human peripheral blood lymphocytes.

    Repurposing sodium diclofenac as a radiation countermeasure agent: A cytogenetic study in human peripheral blood lymphocytes.
    Alok A, Agrawala PK.

    11/21/2020
    firstprevious page of 13 nextlast