| Identification and validation of an H2AZ1-based index model: a novel prognostic tool for hepatocellular carcinoma. | Identification and validation of an H2AZ1-based index model: a novel prognostic tool for hepatocellular carcinoma.
Gao J, Lu Q, Zhong J, Li Z, Pan L, Feng C, Tang S, Wang X, Tao Y, Zhou X, Wang Q., Free PMC Article | 02/23/2024 |
| SENP5 promotes homologous recombination-mediated DNA damage repair in colorectal cancer cells through H2AZ deSUMOylation. | SENP5 promotes homologous recombination-mediated DNA damage repair in colorectal cancer cells through H2AZ deSUMOylation.
Liu T, Wang H, Chen Y, Wan Z, Du Z, Shen H, Yu Y, Ma S, Xu Y, Li Z, Yu N, Zhang F, Cao K, Cai J, Zhang W, Gao F, Yang Y., Free PMC Article | 09/11/2023 |
| MicroRNA-455-3p accelerate malignant progression of tumor by targeting H2AFZ in colorectal cancer. | MicroRNA-455-3p accelerate malignant progression of tumor by targeting H2AFZ in colorectal cancer.
Ye L, Fan T, Qin Y, Qiu C, Li L, Dai M, Zhou Y, Chen Y, Jiang Y., Free PMC Article | 03/16/2023 |
| Interplay Between the Histone Variant H2A.Z and the Epigenome in Pancreatic Cancer. | Interplay Between the Histone Variant H2A.Z and the Epigenome in Pancreatic Cancer.
Ávila-López PA, Nuñez-Martínez HN, Peralta-Alvarez CA, Martinez-Calvillo S, Recillas-Targa F, Hernández-Rivas R. | 03/3/2023 |
| The H2A.Z-KDM1A complex promotes tumorigenesis by localizing in the nucleus to promote SFRP1 promoter methylation in cholangiocarcinoma cells. | The H2A.Z-KDM1A complex promotes tumorigenesis by localizing in the nucleus to promote SFRP1 promoter methylation in cholangiocarcinoma cells.
Wang Q, Qi Y, Xiong F, Wang D, Wang B, Chen Y., Free PMC Article | 11/19/2022 |
| Analysis of histone variant constraint and tissue expression suggests five potential novel human disease genes: H2AFY2, H2AFZ, H2AFY, H2AFV, H1F0. | Analysis of histone variant constraint and tissue expression suggests five potential novel human disease genes: H2AFY2, H2AFZ, H2AFY, H2AFV, H1F0.
Lubin E, Bryant L, Aicher J, Li D, Bhoj E. | 08/6/2022 |
| H2A Histone Family Member Z (H2AFZ) Serves as a Prognostic Biomarker in Lung Adenocarcinoma: Bioinformatic Analysis and Experimental Validation. | H2A Histone Family Member Z (H2AFZ) Serves as a Prognostic Biomarker in Lung Adenocarcinoma: Bioinformatic Analysis and Experimental Validation.
Li Z, Hu M, Qiu J, Feng J, Zhang R, Wu H, Hu G, Ren J., Free PMC Article | 03/19/2022 |
| Characterization of Cancer Stem Cell Characteristics and Development of a Prognostic Stemness Index Cell-Related Signature in Oral Squamous Cell Carcinoma. | Characterization of Cancer Stem Cell Characteristics and Development of a Prognostic Stemness Index Cell-Related Signature in Oral Squamous Cell Carcinoma.
Feng J, Li Y, Wen N., Free PMC Article | 03/12/2022 |
| Linking nuclear matrix-localized PIAS1 to chromatin SUMOylation via direct binding of histones H3 and H2A.Z. | Linking nuclear matrix-localized PIAS1 to chromatin SUMOylation via direct binding of histones H3 and H2A.Z.
Chen Z, Zhang Y, Guan Q, Zhang H, Luo J, Li J, Wei W, Xu X, Liao L, Wong J, Li J., Free PMC Article | 11/27/2021 |
| H2A.Z acetylation by lincZNF337-AS1 via KAT5 implicated in the transcriptional misregulation in cancer signaling pathway in hepatocellular carcinoma. | H2A.Z acetylation by lincZNF337-AS1 via KAT5 implicated in the transcriptional misregulation in cancer signaling pathway in hepatocellular carcinoma.
Yuan Y, Cao W, Zhou H, Qian H, Wang H., Free PMC Article | 11/6/2021 |
| Deficient H2A.Z deposition is associated with genesis of uterine leiomyoma. | Deficient H2A.Z deposition is associated with genesis of uterine leiomyoma.
Berta DG, Kuisma H, Välimäki N, Räisänen M, Jäntti M, Pasanen A, Karhu A, Kaukomaa J, Taira A, Cajuso T, Nieminen S, Penttinen RM, Ahonen S, Lehtonen R, Mehine M, Vahteristo P, Jalkanen J, Sahu B, Ravantti J, Mäkinen N, Rajamäki K, Palin K, Taipale J, Heikinheimo O, Bützow R, Kaasinen E, Aaltonen LA. | 10/30/2021 |
| The N-terminal and C-terminal halves of histone H2A.Z independently function in nucleosome positioning and stability. | The N-terminal and C-terminal halves of histone H2A.Z independently function in nucleosome positioning and stability.
Sato S, Tanaka N, Arimura Y, Kujirai T, Kurumizaka H., Free PMC Article | 07/3/2021 |
| Structural basis of nucleosome dynamics modulation by histone variants H2A.B and H2A.Z.2.2. | Structural basis of nucleosome dynamics modulation by histone variants H2A.B and H2A.Z.2.2.
Zhou M, Dai L, Li C, Shi L, Huang Y, Guo Z, Wu F, Zhu P, Zhou Z., Free PMC Article | 06/26/2021 |
| Multiple roles of H2A.Z in regulating promoter chromatin architecture in human cells. | Multiple roles of H2A.Z in regulating promoter chromatin architecture in human cells.
Cole L, Kurscheid S, Nekrasov M, Domaschenz R, Vera DL, Dennis JH, Tremethick DJ., Free PMC Article | 05/29/2021 |
| Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation. | Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation.
Lamaa A, Humbert J, Aguirrebengoa M, Cheng X, Nicolas E, Côté J, Trouche D., Free PMC Article | 04/13/2021 |
| VPS72/YL1-Mediated H2A.Z Deposition Is Required for Nuclear Reassembly after Mitosis. | VPS72/YL1-Mediated H2A.Z Deposition Is Required for Nuclear Reassembly after Mitosis.
Moreno-Andrés D, Yokoyama H, Scheufen A, Holzer G, Lue H, Schellhaus AK, Weberruss M, Takagi M, Antonin W., Free PMC Article | 03/6/2021 |
| these results illuminate the mechanism underlying a human syndrome and uncover selective functions of H2A.Z subtypes during development. | Single Amino Acid Change Underlies Distinct Roles of H2A.Z Subtypes in Human Syndrome.
Greenberg RS, Long HK, Swigut T, Wysocka J., Free PMC Article | 06/20/2020 |
| results suggest that the histone variant H2A.Z epigenetically regulates the licensing and activation of early replication origins and maintains replication timing through the SUV420H1-H4K20me2-ORC1 axis | H2A.Z facilitates licensing and activation of early replication origins.
Long H, Zhang L, Lv M, Wen Z, Zhang W, Chen X, Zhang P, Li T, Chang L, Jin C, Wu G, Wang X, Yang F, Pei J, Chen P, Margueron R, Deng H, Zhu M, Li G. | 05/9/2020 |
| Conclusively, chromatin immunoprecipitation-deep sequencing, confirmed the predominant association of OGDH and ACAA2 with H2A.Z-occupied transcription start sites and enhancers, the former of which we confirmed is conserved in both mouse and human tissue. | Oxoglutarate dehydrogenase and acetyl-CoA acyltransferase 2 selectively associate with H2A.Z-occupied promoters and are required for histone modifications.
Choi S, Pfleger J, Jeon YH, Yang Z, He M, Shin H, Sayed D, Astrof S, Abdellatif M., Free PMC Article | 02/1/2020 |
| Data show that loading and acetylation of H2A.Z are required to assure tight control of canonical notch receptor (Notch) activation. | Histone variant H2A.Z deposition and acetylation directs the canonical Notch signaling response.
Giaimo BD, Ferrante F, Vallejo DM, Hein K, Gutierrez-Perez I, Nist A, Stiewe T, Mittler G, Herold S, Zimmermann T, Bartkuhn M, Schwarz P, Oswald F, Dominguez M, Borggrefe T., Free PMC Article | 08/17/2019 |
| FBXL10-RNF68-RNF2 ubiquitin ligase complex (FRRUC) is rapidly and transiently recruited to sites of DNA damage in a PARP1- and TIMELESS-dependent manner to promote mono-ubiquitylation of H2A at Lys119. | PARP1-dependent recruitment of the FBXL10-RNF68-RNF2 ubiquitin ligase to sites of DNA damage controls H2A.Z loading.
Rona G, Roberti D, Yin Y, Pagan JK, Homer H, Sassani E, Zeke A, Busino L, Rothenberg E, Pagano M., Free PMC Article | 03/30/2019 |
| H2A.Z associates with epigenetic gene activation in prostate cancer.Acetylated H2A.Z role in activation of newly formed enhancers in prostate cancer. | Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer.
Valdés-Mora F, Gould CM, Colino-Sanguino Y, Qu W, Song JZ, Taylor KM, Buske FA, Statham AL, Nair SS, Armstrong NJ, Kench JG, Lee KML, Horvath LG, Qiu M, Ilinykh A, Yeo-Teh NS, Gallego-Ortega D, Stirzaker C, Clark SJ., Free PMC Article | 09/22/2018 |
| The present study demonstrated that H2A.Z is overexpressed in ICC and expression of H2A.Z correlated with poor prognosis in patients with ICC. H2A.Z regulated cell proliferation in vitro and in vivo via H2A.Z/S-phase kinase-associated protein 2/p27/p21 signaling. | H2A.Z regulates tumorigenesis, metastasis and sensitivity to cisplatin in intrahepatic cholangiocarcinoma.
Yang B, Tong R, Liu H, Wu J, Chen D, Xue Z, Ding C, Zhou L, Xie H, Wu J, Zheng S., Free PMC Article | 09/1/2018 |
| study identifies GAS41 as a histone acetylation reader that promotes histone H2A.Z deposition in non-small cell lung cancer. | Recognition of histone acetylation by the GAS41 YEATS domain promotes H2A.Z deposition in non-small cell lung cancer.
Hsu CC, Shi J, Yuan C, Zhao D, Jiang S, Lyu J, Wang X, Li H, Wen H, Li W, Shi X., Free PMC Article | 06/9/2018 |
| Two possible modes of pioneering associated with combinations of H2A.Z and p300/CBP at nucleosome-occupied enhancers. | Two possible modes of pioneering associated with combinations of H2A.Z and p300/CBP at nucleosome-occupied enhancers.
Cauchy P, Koch F, Andrau JC., Free PMC Article | 02/10/2018 |