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    HDAC1 histone deacetylase 1 [ Homo sapiens (human) ]

    Gene ID: 3065, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    PHF12 regulates HDAC1 to promote tumorigenesis via EGFR/AKT signaling pathway in non-small cell lung cancer.

    PHF12 regulates HDAC1 to promote tumorigenesis via EGFR/AKT signaling pathway in non-small cell lung cancer.
    Kong Y, Jiang R, Zhou H, Ge M, Lin H, Wang Y, Yao R, Wang Q, Liang X, Li J, Zhou X., Free PMC Article

    09/6/2024
    Interplay between DOT1L and HDAC1 regulates Leishmania donovani infection in human THP-1 cells.

    Interplay between DOT1L and HDAC1 regulates Leishmania donovani infection in human THP-1 cells.
    Kanojia A, Roy G, Madhubala R, Muthuswami R.

    09/5/2024
    HDAC4 influences the DNA damage response and counteracts senescence by assembling with HDAC1/HDAC2 to control H2BK120 acetylation and homology-directed repair.

    HDAC4 influences the DNA damage response and counteracts senescence by assembling with HDAC1/HDAC2 to control H2BK120 acetylation and homology-directed repair.
    Di Giorgio E, Dalla E, Tolotto V, D'Este F, Paluvai H, Ranzino L, Brancolini C., Free PMC Article

    08/22/2024
    Unveiling the role of HP1alpha-HDAC1-STAT1 axis as a therapeutic target for HP1alpha-positive intrahepatic cholangiocarcinoma.

    Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma.
    Xiong F, Wang D, Xiong W, Wang X, Huang WH, Wu GH, Liu WZ, Wang Q, Chen JS, Kuai YY, Wang B, Chen YJ., Free PMC Article

    06/6/2024
    HDAC1-Mediated Downregulation of NEU1 Exacerbates the Aggressiveness of Cervical Cancer.

    HDAC1-Mediated Downregulation of NEU1 Exacerbates the Aggressiveness of Cervical Cancer.
    Xie N, Mei S, Dai C, Chen W.

    03/21/2024
    ZNF787 and HDAC1 Mediate Blood-Brain Barrier Permeability in an In Vitro Model of Alzheimer's Disease Microenvironment.

    ZNF787 and HDAC1 Mediate Blood-Brain Barrier Permeability in an In Vitro Model of Alzheimer's Disease Microenvironment.
    Zhang L, Zhu B, Zhou X, Ning H, Zhang F, Yan B, Chen J, Ma T.

    02/13/2024
    HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-alpha5beta1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling.

    HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-α5β1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling.
    Terri M, Sandoval P, Bontempi G, Montaldo C, Tomero-Sanz H, de Turris V, Trionfetti F, Pascual-Antón L, Clares-Pedrero I, Battistelli C, Valente S, Zwergel C, Mai A, Rosanò L, Del Pozo MÁ, Sánchez-Álvarez M, Cabañas C, Tripodi M, López-Cabrera M, Strippoli R., Free PMC Article

    02/12/2024
    Homeobox Protein PROX1 Expression is Negatively Regulated by Histone Deacetylase 1 and c-JUN Complex in MDA-MB-231 Human Breast Cancer Cells.

    Homeobox Protein PROX1 Expression is Negatively Regulated by Histone Deacetylase 1 and c-JUN Complex in MDA-MB-231 Human Breast Cancer Cells.
    Jeong M, Jung E, Oh S, Shin SY.

    01/17/2024
    GSE1 links the HDAC1/CoREST co-repressor complex to DNA damage.

    GSE1 links the HDAC1/CoREST co-repressor complex to DNA damage.
    Vcelkova T, Reiter W, Zylka M, Hollenstein DM, Schuckert S, Hartl M, Seiser C., Free PMC Article

    12/1/2023
    HDAC1 suppresses radiotherapy sensitivity in cervical cancer via regulating HIF-1alpha/VEGF signaling pathway.

    HDAC1 suppresses radiotherapy sensitivity in cervical cancer via regulating HIF-1α/VEGF signaling pathway.
    Liu L, Gu K, Hua D.

    12/1/2023
    Genomic analysis reveals HDAC1 regulates clinically relevant transcriptional programs in Pancreatic cancer.

    Genomic analysis reveals HDAC1 regulates clinically relevant transcriptional programs in Pancreatic cancer.
    Wright CA, Gordon ER, Cooper SJ., Free PMC Article

    11/28/2023
    BCL11B and the NuRD complex cooperatively guard T-cell fate and inhibit OPA1-mediated mitochondrial fusion in T cells.

    BCL11B and the NuRD complex cooperatively guard T-cell fate and inhibit OPA1-mediated mitochondrial fusion in T cells.
    Liao R, Wu Y, Qin L, Jiang Z, Gou S, Zhou L, Hong Q, Li Y, Shi J, Yao Y, Lai L, Li Y, Liu P, Thiery JP, Qin D, Graf T, Liu X, Li P., Free PMC Article

    11/8/2023
    Evaluation of epigenetic-related gene expression (DNMT, HDAC1) in Iranian patients with systemic lupus erythematosus.

    Evaluation of epigenetic-related gene expression (DNMT, HDAC1) in Iranian patients with systemic lupus erythematosus.
    Abbasifard M, Mohammadiranjbar F, Mohammad-Sadeghipour M, Mahmoodi M, Hassanshahi G, Swann J, Zarei S, Hosseiniara R, Hajizadeh MR.

    11/6/2023
    HDAC1 regulates the chromatin landscape to control transcriptional dependencies in chronic lymphocytic leukemia.

    HDAC1 regulates the chromatin landscape to control transcriptional dependencies in chronic lymphocytic leukemia.
    Lai TH, Ozer HG, Gasparini P, Nigita G, Distefano R, Yu L, Ravikrishnan J, Yilmaz S, Gallegos J, Shukla S, Puduvalli V, Woyach J, Lapalombella R, Blachly J, Byrd JC, Sampath D., Free PMC Article

    06/22/2023
    HDAC1 mediates epithelial-mesenchymal transition and promotes cancer cell invasion in glioblastoma.

    HDAC1 mediates epithelial-mesenchymal transition and promotes cancer cell invasion in glioblastoma.
    Cheng Z, Li S, Yuan J, Li Y, Cheng S, Huang S, Dong J.

    05/28/2023
    Proteomics-based trapping with single or multiple inactive mutants reproducibly profiles histone deacetylase 1 substrates.

    Proteomics-based trapping with single or multiple inactive mutants reproducibly profiles histone deacetylase 1 substrates.
    Herath KE, Kodikara IKM, Pflum MKH.

    02/11/2023
    Regulation of osteogenesis in bone marrow-derived mesenchymal stem cells via histone deacetylase 1 and 2 co-cultured with human gingival fibroblasts and periodontal ligament cells.

    Regulation of osteogenesis in bone marrow-derived mesenchymal stem cells via histone deacetylase 1 and 2 co-cultured with human gingival fibroblasts and periodontal ligament cells.
    Iwata T, Kaneda-Ikeda E, Takahashi K, Takeda K, Nagahara T, Kajiya M, Sasaki S, Ishida S, Yoshioka M, Matsuda S, Ouhara K, Fujita T, Kurihara H, Mizuno N.

    01/21/2023
    Histone deacetylase 1, Sirtuin 1, and Sirtuin 3 single-nucleotide polymorphisms and the risk of endometriosis in South Indian women.

    Histone deacetylase 1, Sirtuin 1, and Sirtuin 3 single-nucleotide polymorphisms and the risk of endometriosis in South Indian women.
    Veena KV, Siddamalla S, Deenadayal M, Sisinthy S, Bhanoori M.

    01/14/2023
    Histone deacetylases 1 and 2 target gene regulatory networks of nephron progenitors to control nephrogenesis.

    Histone deacetylases 1 and 2 target gene regulatory networks of nephron progenitors to control nephrogenesis.
    Liu H, Ngo NYN, Herzberger KF, Gummaraju M, Hilliard S, Chen CH.

    12/10/2022
    HDAC1/3-dependent moderate liquid-liquid phase separation of YY1 promotes METTL3 expression and AML cell proliferation.

    HDAC1/3-dependent moderate liquid-liquid phase separation of YY1 promotes METTL3 expression and AML cell proliferation.
    Li M, Li M, Xia Y, Li G, Su X, Wang D, Ye J, Lu F, Sun T, Ji C., Free PMC Article

    12/3/2022
    The emerging role of histone deacetylase 1 in allergic diseases.

    The emerging role of histone deacetylase 1 in allergic diseases.
    Wang Y, Wang H., Free PMC Article

    11/5/2022
    Epigenetic master regulators HDAC1 and HDAC5 control pathobiont Enterobacteria colonization in ileal mucosa of Crohn's disease patients.

    Epigenetic master regulators HDAC1 and HDAC5 control pathobiont Enterobacteria colonization in ileal mucosa of Crohn's disease patients.
    Chervy M, Sivignon A, Dambrine F, Buisson A, Sauvanet P, Godfraind C, Allez M, Le Bourhis L, The Remind Group, Barnich N, Denizot J., Free PMC Article

    10/8/2022
    LncRNA SNHG1 regulates neuroblastoma cell fate via interactions with HDAC1/2.

    LncRNA SNHG1 regulates neuroblastoma cell fate via interactions with HDAC1/2.
    Hsu CL, Yin CF, Chang YW, Fan YC, Lin SH, Wu YC, Huang HC, Juan HF., Free PMC Article

    10/1/2022
    Identification and Validation of CDKN1A and HDAC1 as Senescence-Related Hub Genes in Chronic Obstructive Pulmonary Disease.

    Identification and Validation of CDKN1A and HDAC1 as Senescence-Related Hub Genes in Chronic Obstructive Pulmonary Disease.
    Yang J, Zhang MY, Du YM, Ji XL, Qu YQ., Free PMC Article

    08/27/2022
    [(11)C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease.

    [(11)C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease.
    Pascoal TA, Chamoun M, Lax E, Wey HY, Shin M, Ng KP, Kang MS, Mathotaarachchi S, Benedet AL, Therriault J, Lussier FZ, Schroeder FA, DuBois JM, Hightower BG, Gilbert TM, Zürcher NR, Wang C, Hopewell R, Chakravarty M, Savard M, Thomas E, Mohaddes S, Farzin S, Salaciak A, Tullo S, Cuello AC, Soucy JP, Massarweh G, Hwang H, Kobayashi E, Hyman BT, Dickerson BC, Guiot MC, Szyf M, Gauthier S, Hooker JM, Rosa-Neto P., Free PMC Article

    07/30/2022
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