| HDAC2 promotes autophagy-associated HCC malignant progression by transcriptionally activating LAPTM4B. | HDAC2 promotes autophagy-associated HCC malignant progression by transcriptionally activating LAPTM4B.
Wang M, Liao J, Wang J, Xu M, Cheng Y, Wei L, Huang A., Free PMC Article | 09/26/2024 |
| ACAP3 negatively regulated by HDAC2 inhibits the malignant development of papillary thyroid carcinoma cells. | ACAP3 negatively regulated by HDAC2 inhibits the malignant development of papillary thyroid carcinoma cells.
Zhan F, Zhang R, Qiu L, Ren Y. | 08/30/2024 |
| HDAC4 influences the DNA damage response and counteracts senescence by assembling with HDAC1/HDAC2 to control H2BK120 acetylation and homology-directed repair. | HDAC4 influences the DNA damage response and counteracts senescence by assembling with HDAC1/HDAC2 to control H2BK120 acetylation and homology-directed repair.
Di Giorgio E, Dalla E, Tolotto V, D'Este F, Paluvai H, Ranzino L, Brancolini C., Free PMC Article | 08/22/2024 |
| Inhibition of HDAC2 sensitises antitumour therapy by promoting NLRP3/GSDMD-mediated pyroptosis in colorectal cancer. | Inhibition of HDAC2 sensitises antitumour therapy by promoting NLRP3/GSDMD-mediated pyroptosis in colorectal cancer.
Guan X, Liu R, Wang B, Xiong R, Cui L, Liao Y, Ruan Y, Fang L, Lu X, Yu X, Su D, Ma Y, Dang T, Chen Z, Yao Y, Liu C, Zhang Y., Free PMC Article | 08/22/2024 |
| The Epigenetic Modifiers HDAC2 and HDAC7 Inversely Associate with Cancer Stemness and Immunity in Solid Tumors. | The Epigenetic Modifiers HDAC2 and HDAC7 Inversely Associate with Cancer Stemness and Immunity in Solid Tumors.
Maciejewski K, Giers M, Oleksiewicz U, Czerwinska P., Free PMC Article | 08/13/2024 |
| Inhibition of endothelial histone deacetylase 2 shifts endothelial-mesenchymal transitions in cerebral arteriovenous malformation models. | Inhibition of endothelial histone deacetylase 2 shifts endothelial-mesenchymal transitions in cerebral arteriovenous malformation models.
Zhao Y, Wu X, Yang Y, Zhang L, Cai X, Chen S, Vera A, Ji J, Boström KI, Yao Y., Free PMC Article | 08/4/2024 |
| Short communication: TNF-alpha and IGF-1 regulates epigenetic mechanisms of HDAC2 and HDAC10. | Short communication: TNF-α and IGF-1 regulates epigenetic mechanisms of HDAC2 and HDAC10.
Jiang W, Block ME, Boosani CS., Free PMC Article | 07/29/2024 |
| SARS-CoV-2 NSP5 antagonizes MHC II expression by subverting histone deacetylase 2. | SARS-CoV-2 NSP5 antagonizes MHC II expression by subverting histone deacetylase 2.
Taefehshokr N, Lac A, Vrieze AM, Dickson BH, Guo PN, Jung C, Blythe EN, Fink C, Aktar A, Dikeakos JD, Dekaban GA, Heit B., Free PMC Article | 06/7/2024 |
| SOX4/HDAC2 Axis Enhances Cell Survivability and Reduces Apoptosis by Activating AKT/MAPK Signaling in Colorectal Cancer. | SOX4/HDAC2 Axis Enhances Cell Survivability and Reduces Apoptosis by Activating AKT/MAPK Signaling in Colorectal Cancer.
S A, Chakraborty A, Patnaik S. | 03/26/2024 |
| HDAC2 counteracts vascular calcification by activating autophagy in chronic kidney disease. | HDAC2 counteracts vascular calcification by activating autophagy in chronic kidney disease.
Zhou G, Liu P, Zhang C, Huang Q, Zhao Z, Wu S, Li D, Liu H. | 02/16/2024 |
| HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-alpha5beta1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling. | HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-α5β1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling.
Terri M, Sandoval P, Bontempi G, Montaldo C, Tomero-Sanz H, de Turris V, Trionfetti F, Pascual-Antón L, Clares-Pedrero I, Battistelli C, Valente S, Zwergel C, Mai A, Rosanò L, Del Pozo MÁ, Sánchez-Álvarez M, Cabañas C, Tripodi M, López-Cabrera M, Strippoli R., Free PMC Article | 02/12/2024 |
| USP17 regulates preeclampsia by modulating the NF-kappaB signaling pathway via deubiquitinating HDAC2. | USP17 regulates preeclampsia by modulating the NF-κB signaling pathway via deubiquitinating HDAC2.
Li A, Wang T, Zhou S, Han J, Wu W. | 01/12/2024 |
| The epigenetic modifier HDAC2 and the checkpoint kinase ATM determine the responses of microsatellite instable colorectal cancer cells to 5-fluorouracil. | The epigenetic modifier HDAC2 and the checkpoint kinase ATM determine the responses of microsatellite instable colorectal cancer cells to 5-fluorouracil.
Kiweler N, Schwarz H, Nguyen A, Matschos S, Mullins C, Piée-Staffa A, Brachetti C, Roos WP, Schneider G, Linnebacher M, Brenner W, Krämer OH., Free PMC Article | 11/1/2023 |
| A novel GRK3-HDAC2 regulatory pathway is a key direct link between neuroendocrine differentiation and angiogenesis in prostate cancer progression. | A novel GRK3-HDAC2 regulatory pathway is a key direct link between neuroendocrine differentiation and angiogenesis in prostate cancer progression.
Naderinezhad S, Zhang G, Wang Z, Zheng D, Hulsurkar M, Bakhoum M, Su N, Yang H, Shen T, Li W., Free PMC Article | 09/1/2023 |
| Mechanism of histone deacetylase HDAC2 in FOXO3-mediated trophoblast pyroptosis in preeclampsia. | Mechanism of histone deacetylase HDAC2 in FOXO3-mediated trophoblast pyroptosis in preeclampsia.
Liu J, Yang W. | 05/15/2023 |
| Knockdown of FKBP3 suppresses nasopharyngeal carcinoma cell growth, invasion and migration, deactivated NF-kappaB/IL-6 signaling pathway through inhibiting histone deacetylase 2 expression. | Knockdown of FKBP3 suppresses nasopharyngeal carcinoma cell growth, invasion and migration, deactivated NF-κB/IL-6 signaling pathway through inhibiting histone deacetylase 2 expression.
Dong J, Chen J, Li Q, Qiu S. | 04/26/2023 |
| Human bone marrow mesenchymal stem cell-derived extracellular vesicles reduce inflammation and pyroptosis in acute kidney injury via miR-223-3p/HDAC2/SNRK. | Human bone marrow mesenchymal stem cell-derived extracellular vesicles reduce inflammation and pyroptosis in acute kidney injury via miR-223-3p/HDAC2/SNRK.
Xie Z, Tang J, Chen Z, Wei L, Chen J, Liu Q., Free PMC Article | 03/21/2023 |
| Regulation of osteogenesis in bone marrow-derived mesenchymal stem cells via histone deacetylase 1 and 2 co-cultured with human gingival fibroblasts and periodontal ligament cells. | Regulation of osteogenesis in bone marrow-derived mesenchymal stem cells via histone deacetylase 1 and 2 co-cultured with human gingival fibroblasts and periodontal ligament cells.
Iwata T, Kaneda-Ikeda E, Takahashi K, Takeda K, Nagahara T, Kajiya M, Sasaki S, Ishida S, Yoshioka M, Matsuda S, Ouhara K, Fujita T, Kurihara H, Mizuno N. | 01/21/2023 |
| Peroxiredoxin2 regulates trophoblast proliferation and migration through SPIB-HDAC2 pathway. | Peroxiredoxin2 regulates trophoblast proliferation and migration through SPIB-HDAC2 pathway.
Wu F, Tian F, Qin C, Qin X, Zeng W, Liu X, Chen C, Lin Y. | 01/14/2023 |
| Interaction of HDAC2 with SARS-CoV-2 NSP5 and IRF3 Is Not Required for NSP5-Mediated Inhibition of Type I Interferon Signaling Pathway. | Interaction of HDAC2 with SARS-CoV-2 NSP5 and IRF3 Is Not Required for NSP5-Mediated Inhibition of Type I Interferon Signaling Pathway.
Naik NG, Lee SC, Veronese BHS, Ma Z, Toth Z., Free PMC Article | 11/5/2022 |
| ELK1 suppresses SYTL1 expression by recruiting HDAC2 in bladder cancer progression. | ELK1 suppresses SYTL1 expression by recruiting HDAC2 in bladder cancer progression.
Wang J, Luo J, Wu X, Li Z. | 10/8/2022 |
| LncRNA SNHG1 regulates neuroblastoma cell fate via interactions with HDAC1/2. | LncRNA SNHG1 regulates neuroblastoma cell fate via interactions with HDAC1/2.
Hsu CL, Yin CF, Chang YW, Fan YC, Lin SH, Wu YC, Huang HC, Juan HF., Free PMC Article | 10/1/2022 |
| Micropillar-based phenotypic screening platform uncovers involvement of HDAC2 in nuclear deformability. | Micropillar-based phenotypic screening platform uncovers involvement of HDAC2 in nuclear deformability.
Martewicz S, Zhu X, Qu S, Cui M, Grespan E, Luni C, Jiang B, Yang G, Elvassore N. | 06/25/2022 |
| MicroRNA-455-3p functions as a tumor suppressor by targeting HDAC2 to regulate cell cycle in hepatocellular carcinoma. | MicroRNA-455-3p functions as a tumor suppressor by targeting HDAC2 to regulate cell cycle in hepatocellular carcinoma.
Ma F, Huang J, Li W, Li P, Liu M, Xue H. | 06/18/2022 |
| GATA binding protein 1 recruits histone deacetylase 2 to the promoter region of nuclear receptor binding protein 2 to affect the tumor microenvironment and malignancy of thyroid carcinoma. | GATA binding protein 1 recruits histone deacetylase 2 to the promoter region of nuclear receptor binding protein 2 to affect the tumor microenvironment and malignancy of thyroid carcinoma.
Li M, Jiang H, Chen S, Ma Y., Free PMC Article | 05/14/2022 |