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    ANXA5 annexin A5 [ Homo sapiens (human) ]

    Gene ID: 308, updated on 10-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    ANXA5: A Key Regulator of Immune Cell Infiltration in Hepatocellular Carcinoma.

    ANXA5: A Key Regulator of Immune Cell Infiltration in Hepatocellular Carcinoma.
    Wang W, Liu D, Yao J, Yuan Z, Yan L, Cao B., Free PMC Article

    06/10/2024
    The Relevance, Predictability, and Utility of Annexin A5 for Human Physiopathology.

    The Relevance, Predictability, and Utility of Annexin A5 for Human Physiopathology.
    Jing J., Free PMC Article

    03/20/2024
    Hepatitis C Virus Disrupts Annexin 5-Mediated Occludin Integrity through Downregulation of Protein Kinase Calpha (PKCalpha) and PKCeta Expression, Thereby Promoting Viral Propagation.

    Hepatitis C Virus Disrupts Annexin 5-Mediated Occludin Integrity through Downregulation of Protein Kinase Cα (PKCα) and PKCη Expression, Thereby Promoting Viral Propagation.
    Abe T, Marutani Y, Deng L, Matsui C, Fukasawa M, Suzuki R, Wakita T, Matsuura Y, Shoji I., Free PMC Article

    07/12/2023
    Annexin-A5 and annexin-A6 silencing prevents metastasis of breast cancer cells in zebrafish.

    Annexin-A5 and annexin-A6 silencing prevents metastasis of breast cancer cells in zebrafish.
    Gounou C, Bouvet F, Liet B, Prouzet-Mauléon V, d'Agata L, Harté E, Argoul F, Siegfried G, Iggo R, Khatib AM, Bouter A.

    06/9/2023
    Increased ANXA5 expression in stomach adenocarcinoma infers a poor prognosis and high level of immune infiltration.

    Increased ANXA5 expression in stomach adenocarcinoma infers a poor prognosis and high level of immune infiltration.
    Su Z, Shu K, Li G.

    10/29/2022
    Annexin A5 as a targeting agent for cancer treatment.

    Annexin A5 as a targeting agent for cancer treatment.
    Woodward A, Faria GNF, Harrison RG.

    09/24/2022
    Association between ANXA5 haplotypes and the risk of recurrent pregnancy loss.

    Association between ANXA5 haplotypes and the risk of recurrent pregnancy loss.
    Zheng M, Yan J, Jiang L, Dai Z, Liu X., Free PMC Article

    08/6/2022
    Clinicopathological study and immunohistochemical analysis of expression of annexin A5 and apelin in human placentae of gestational diabetes mellitus.

    Clinicopathological study and immunohistochemical analysis of expression of annexin A5 and apelin in human placentae of gestational diabetes mellitus.
    Dasgupta S, Banerjee U, Mukhopadhyay P, Maity P, Saha S, Das B.

    04/9/2022
    Genetic analysis of ANXA5 haplotype and its effect on recurrent pregnancy loss.

    Genetic analysis of ANXA5 haplotype and its effect on recurrent pregnancy loss.
    Cai Z, Zheng X, Chen Y, Chen F, Chen L, Deng X.

    03/12/2022
    Differential expression of Lumican, Mimecan, Annexin A5 and Serotransferrin in ectopic and matched eutopic endometrium in ovarian endometriosis: a case-control study.

    Differential expression of Lumican, Mimecan, Annexin A5 and Serotransferrin in ectopic and matched eutopic endometrium in ovarian endometriosis: a case-control study.
    Sahar T, Nigam A, Anjum S, Waziri F, Jain SK, Wajid S.

    10/23/2021
    Maternal and paternal carriage of the annexin A5 M2 haplotype: a possible risk factor for recurrent implantation failure (RIF).

    Maternal and paternal carriage of the annexin A5 M2 haplotype: a possible risk factor for recurrent implantation failure (RIF).
    Rogenhofer N, Markoff A, Ennerst X, Bogdanova N, Thaler C., Free PMC Article

    07/3/2021
    Human L-Dopa decarboxylase interaction with annexin V and expression during apoptosis.

    Human L-Dopa decarboxylase interaction with annexin V and expression during apoptosis.
    Chalatsa I, Arvanitis N, Arvanitis D, Tsakou AC, Kalantzis ED, Vassiliou AG, Sideris DC, Frakolaki E, Vassilaki N, Vassilacopoulou D.

    05/29/2021
    High-resolution structures of annexin A5 in a two-dimensional array.

    High-resolution structures of annexin A5 in a two-dimensional array.
    Hong S, Na S, Kim OH, Jeong S, Oh BC, Ha NC.

    04/17/2021
    Annexin A5 is essential for PKCtheta translocation during T-cell activation.

    Annexin A5 is essential for PKCθ translocation during T-cell activation.
    Hu Z, Li L, Zhu B, Huang Y, Wang X, Lin X, Li M, Xu P, Zhang X, Zhang J, Hua Z., Free PMC Article

    02/20/2021
    Correlation of single nucleotide polymorphisms in the promoter region of the ANXA5 (annexin A5) gene with recurrent miscarriages in women of Greek origin.

    Correlation of single nucleotide polymorphisms in the promoter region of the ANXA5 (annexin A5) gene with recurrent miscarriages in women of Greek origin.
    Dryllis G, Giannopoulos A, Zoi C, Pouliakis A, Logothetis E, Voulgarelis M, Zoi K, Kouskouni E, Dinou A, Stavropoulos-Giokas C, Kreatsas G, Konstantopoulos K, Politou M.

    01/23/2021
    Matrix vesicle biomimetics harboring Annexin A5 and alkaline phosphatase bind to the native collagen matrix produced by mineralizing vascular smooth muscle cells.

    Matrix vesicle biomimetics harboring Annexin A5 and alkaline phosphatase bind to the native collagen matrix produced by mineralizing vascular smooth muscle cells.
    Bolean M, Izzi B, van Kerckhoven S, Bottini M, Ramos AP, Millán JL, Hoylaerts MF, Ciancaglini P., Free PMC Article

    12/26/2020
    Annexin V in children with idiopathic nephrotic syndrome treated with cyclosporine A.

    Annexin V in children with idiopathic nephrotic syndrome treated with cyclosporine A.
    Jakubowska A, Kiliś-Pstrusińska K.

    10/10/2020
    The activity of ANXA5 as well as the mRNA/protein expression of ANXA5 was significantly downregulated in RPL patients.

    Genetic variations and haplotypes in the annexin A5 gene are associated with the risk of recurrent pregnancy loss.
    Lan Y, Wang J, Zhang Q, Yang X, Li L, Yin J, Li H, Song X, Chen Z, Liu Y.

    05/30/2020
    CD4+ ANXA5+ T cells represent a novel unique Treg cell subset exhibiting similarities to conventional Treg cells but with a distinct phenotype and function.

    Annexin V expression on CD4(+) T cells with regulatory function.
    Bollinger AL, Bollinger T, Rupp J, Shima K, Gross N, Padayachy L, Chicheportiche R, Puga Yung GL, Seebach JD., Free PMC Article

    02/8/2020
    Clinical Impact on Pregnancy Outcome and Relationship with the M2 Haplotype in the Annexin A5 (ANXA5) Gene

    Antiphospholipid Antibodies in a General Obstetric Population: Clinical Impact on Pregnancy Outcome and Relationship with the M2 Haplotype in the Annexin A5 (ANXA5) Gene.
    Villani M, Colaizzo D, Martinelli P, Cappucci F, Fischetti L, Maruotti GM, Intrieri M, Greco L, Chinni E, Tiscia GL, Margaglione M, Grandone E, PRENACEL Study Group.

    01/4/2020
    Athough the infertile patient groups had a higher prevalence of promoter variants, we could not demonstrate any biologically relevant effect of lower levels of annexin A5 on most male fertility parameters. A deficiency in an anticoagulation factor does not seem to impact male fertility.

    The relevance of ANXA5 genetic variants on male fertility.
    Lavorato HL, Markoff A, Altholz V, Bogdanova N, Wieacker P, Kliesch S, Schlatt S., Free PMC Article

    12/14/2019
    Anxa5 was able to mediate hepatocellular carcinoma carcinogenesis via integrin and MEK-ERK pathways.

    Annexin A5 regulates hepatocarcinoma malignancy via CRKI/II-DOCK180-RAC1 integrin and MEK-ERK pathways.
    Sun X, Liu S, Wang J, Wei B, Guo C, Chen C, Sun MZ., Free PMC Article

    11/30/2019
    The transbilayer movement of phospholipids facilitates the transport of annexins A2 and A5 across membranes in cells and in liposomes.

    Transbilayer phospholipid movement facilitates the translocation of annexin across membranes.
    Stewart SE, Ashkenazi A, Williamson A, Rubinsztein DC, Moreau K., Free PMC Article

    10/26/2019
    This meta-analysis ascertains that women with the M2/ANXA5 haplotype have a higher risk of experiencing repeated pregnancy loss.

    Association between M2/ANXA5 haplotype and repeated pregnancy loss: a meta-analysis.
    Ang KC, Bogdanova N, Markoff A, Ch'ng ES, Tang TH.

    09/7/2019
    Our results imply that ANXA5 plays a potential role in asthma pathogenesis and may be a promising marker for exacerbated bronchial asthma and exposure to air pollutants.

    Annexin A5 Protein as a Potential Biomarker for the Diagnosis of Asthma.
    Lee SH, Lee PH, Kim BG, Hong J, Jang AS.

    07/20/2019
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