| SOCS7-Derived BC-Box Motif Peptide Mediated Cholinergic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells. | SOCS7-Derived BC-Box Motif Peptide Mediated Cholinergic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells.
Kanno H, Matsumoto S, Yoshizumi T, Nakahara K, Shinonaga M, Kubo A, Fujii S, Ishizuka Y, Tanaka M, Ichihashi M, Murata H., Free PMC Article | 02/17/2023 |
| Lack of association between SOCS3 and SOCS7 polymorphisms and psoriasis. | Lack of association between SOCS3 and SOCS7 polymorphisms and psoriasis.
Özçep M, Atsü N, Solak N, Çelik SK., Free PMC Article | 10/8/2022 |
| The E3 ubiquitin ligase SOCS-7 reverses immunosuppression via Shc1 signaling in hepatocellular carcinoma. | The E3 ubiquitin ligase SOCS-7 reverses immunosuppression via Shc1 signaling in hepatocellular carcinoma.
Huang P, Zhao Z, Chen Y, Yang B, Xia J. | 06/11/2022 |
| Long noncoding RNA UCA1 regulates HCV replication and antiviral response via miR-145-5p/SOCS7/IFN pathway. | Long noncoding RNA UCA1 regulates HCV replication and antiviral response via miR-145-5p/SOCS7/IFN pathway.
Zeng H, Li L, Gao Y, Wu G, Hou Z, Liu S., Free PMC Article | 03/19/2022 |
| This study showed that increased protein levels of SOCS-4 and SOCS-7 in Alzheimer's disease brains. | Expression of suppressor of cytokine signaling genes in human elderly and Alzheimer's disease brains and human microglia.
Walker DG, Whetzel AM, Lue LF., Free PMC Article | 04/30/2016 |
| This SOCS7 knockdown-attributed effect could be due to a precise anti-PLCg-1 role. | In vitro and in vivo effects of suppressor of cytokine signalling 7 knockdown in breast cancer: the influence on cellular response to hepatocyte growth factor.
Sasi W, Ye L, Jiang WG, Sharma AK, Mokbel K., Free PMC Article | 05/30/2015 |
| genetic variants in the SOCS7 gene do not impact variation in glucose homeostasis traits and only minimally impact risk of T2DM in the Old Order Amish | Polymorphisms in the SOCS7 gene and glucose homeostasis traits.
Capuano MM, Sorkin JD, Chang YP, Ling H, O'Connell JR, Rothman PB, Mitchell BD, Silver KD., Free PMC Article | 04/4/2015 |
| Insulin Like Growth Factor I treatment and SOCS7 loss have synergistically resulted in increased growth and migration of MCF7 and in increased migration of MDA-MB-231 cells. | Observations on the effects of Suppressor of Cytokine Signaling 7 (SOCS7) knockdown in breast cancer cells: their in vitro response to Insulin Like Growth Factor I (IGF-I).
Sasi W, Ye L, Jiang WG, Mokbel K, Sharma A. | 12/27/2014 |
| The present report describes for the first time associations between common variants in SOCS7 gene and obesity, central obesity, insulin resistance and disorders of lipid metabolism in nondiabetic men from Argentina. | Common variants in SOCS7 gene predict obesity, disturbances in lipid metabolism and insulin resistance.
Tellechea ML, Steinhardt AP, Rodriguez G, Taverna MJ, Poskus E, Frechtel G. | 01/4/2014 |
| SOCS7 functioned as an oncogene, the finding that revealed a novel mechanism of carcinogenesis in bladder cancer cells. | socs7, a target gene of microRNA-145, regulates interferon-β induction through STAT3 nuclear translocation in bladder cancer cells.
Noguchi S, Yamada N, Kumazaki M, Yasui Y, Iwasaki J, Naito S, Akao Y., Free PMC Article | 06/22/2013 |
| LNCaP-S17 cells are resistant to exogenous IL-6-induced neuroendocrine differentiation due to increased levels of CIS/SOCS7 that block activation of JAK2-STAT3 pathways. | LNCaP prostate cancer cells with autocrine interleukin-6 expression are resistant to IL-6-induced neuroendocrine differentiation due to increased expression of suppressors of cytokine signaling.
Ge D, Gao AC, Zhang Q, Liu S, Xue Y, You Z., Free PMC Article | 10/6/2012 |
| Higher mRNA expression levels of SOCS1, 3, 4 and 7 are significantly associated with earlier tumour stage and better clinical outcome in human breast cancer. | Higher expression levels of SOCS 1,3,4,7 are associated with earlier tumour stage and better clinical outcome in human breast cancer.
Sasi W, Jiang WG, Sharma A, Mokbel K., Free PMC Article | 08/23/2010 |
| findings show that PPAR-gamma is involved in the regulation of SOCS-7 expression by hepatitis C virus core protein genotype 3a | Hepatitis C virus core protein genotype 3a increases SOCS-7 expression through PPAR-{gamma} in Huh-7 cells.
Pazienza V, Vinciguerra M, Andriulli A, Mangia A. | 07/12/2010 |
| Demonstrate connection between septins/SOCS7/NCK signaling and the DNA damage response. | Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7.
Kremer BE, Adang LA, Macara IG., Free PMC Article | 01/21/2010 |
| data suggest that SOCS7 is a potent regulator of glucose homeostasis and insulin signaling | Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans.
Banks AS, Li J, McKeag L, Hribal ML, Kashiwada M, Accili D, Rothman PB., Free PMC Article | 01/21/2010 |
| Results indicate that SOCS-7 is a dysregulator of prolactin, leptin, and growth hormone signaling and that its mode of action is a variation of SOCS protein inhibition of cytokine-inducible STAT3 and 5-mediated signal transduction. | Suppressor of cytokine signaling 7 inhibits prolactin, growth hormone, and leptin signaling by interacting with STAT5 or STAT3 and attenuating their nuclear translocation.
Martens N, Uzan G, Wery M, Hooghe R, Hooghe-Peters EL, Gertler A. | 01/21/2010 |
| Taken together, our data indicate that SOCS-7 interacts with vinexin and the actin cytoskeleton. | The suppressor of cytokine signaling (SOCS)-7 interacts with the actin cytoskeleton through vinexin.
Martens N, Wery M, Wang P, Braet F, Gertler A, Hooghe R, Vandenhaute J, Hooghe-Peters EL. | 01/21/2010 |