| Diagnostic and prognostic utility of TROP-2, SLP-2, and CXCL12 expression in papillary thyroid carcinoma. | Diagnostic and prognostic utility of TROP-2, SLP-2, and CXCL12 expression in papillary thyroid carcinoma.
Attia AS, Hussein S, Sameh H, Khalil A, Waley AB, Matar I, Sameh R., Free PMC Article | 04/2/2024 |
| Overexpressing lipid raft protein STOML2 modulates the tumor microenvironment via NF-kappaB signaling in colorectal cancer. | Overexpressing lipid raft protein STOML2 modulates the tumor microenvironment via NF-κB signaling in colorectal cancer.
Gong H, Chen S, Liu S, Hu Q, Li Y, Li Y, Li G, Huang K, Li R, Fang L., Free PMC Article | 02/6/2024 |
| STOML2 restricts mitophagy and increases chemosensitivity in pancreatic cancer through stabilizing PARL-induced PINK1 degradation. | STOML2 restricts mitophagy and increases chemosensitivity in pancreatic cancer through stabilizing PARL-induced PINK1 degradation.
Qin C, Wang Y, Zhao B, Li Z, Li T, Yang X, Zhao Y, Wang W., Free PMC Article | 03/16/2023 |
| CHCHD10 and SLP2 control the stability of the PHB complex: a key factor for motor neuron viability. | CHCHD10 and SLP2 control the stability of the PHB complex: a key factor for motor neuron viability.
Genin EC, Bannwarth S, Ropert B, Lespinasse F, Mauri-Crouzet A, Augé G, Fragaki K, Cochaud C, Donnarumma E, Lacas-Gervais S, Wai T, Paquis-Flucklinger V. | 10/29/2022 |
| Characterization of the interactome of c-Src within the mitochondrial matrix by proximity-dependent biotin identification. | Characterization of the interactome of c-Src within the mitochondrial matrix by proximity-dependent biotin identification.
Guedouari H, Ould Amer Y, Pichaud N, Hebert-Chatelain E. | 11/6/2021 |
| Stomatinlike protein 2 induces metastasis by regulating the expression of a ratelimiting enzyme of the hexosamine biosynthetic pathway in pancreatic cancer. | Stomatin‑like protein 2 induces metastasis by regulating the expression of a rate‑limiting enzyme of the hexosamine biosynthetic pathway in pancreatic cancer.
Chao D, Ariake K, Sato S, Ohtsuka H, Takadate T, Ishida M, Masuda K, Maeda S, Miura T, Mitachi K, Yu XJ, Fujishima F, Mizuma M, Nakagawa K, Morikawa T, Kamei T, Unno M., Free PMC Article | 11/6/2021 |
| Stomatin-Like Protein-2: A Potential Target to Treat Mitochondrial Cardiomyopathy. | Stomatin-Like Protein-2: A Potential Target to Treat Mitochondrial Cardiomyopathy.
Hu Y, Xu Y, Chen W, Qiu Z. | 10/2/2021 |
| Stomatin-like protein 2 (SLP2) regulates the proliferation and invasion of trophoblast cells by modulating mitochondrial functions. | Stomatin-like protein 2 (SLP2) regulates the proliferation and invasion of trophoblast cells by modulating mitochondrial functions.
Zhang X, Li BY, Fu LJ, Adu-Gyamfi EA, Xu BR, Liu TH, Chen XM, Lan X, Wang YX, Xu HB, Ding YB. | 08/14/2021 |
| STOML2 potentiates metastasis of hepatocellular carcinoma by promoting PINK1-mediated mitophagy and regulates sensitivity to lenvatinib. | STOML2 potentiates metastasis of hepatocellular carcinoma by promoting PINK1-mediated mitophagy and regulates sensitivity to lenvatinib.
Zheng Y, Huang C, Lu L, Yu K, Zhao J, Chen M, Liu L, Sun Q, Lin Z, Zheng J, Chen J, Zhang J., Free PMC Article | 06/19/2021 |
| Clinical significance of SLP-2 in epithelial ovarian cancer and its regulatory effect on the Notch signaling pathway. | Clinical significance of SLP-2 in epithelial ovarian cancer and its regulatory effect on the Notch signaling pathway.
Guo XY, Guo HF, Guo HM. | 03/6/2021 |
| SLP-2 promotes non-small cell lung cancer cell proliferation by enhancing survivin expression mediated through the TCF4/beta-catenin pathway. | Stomatin-like protein 2 regulates survivin expression in non-small cell lung cancer cells through β-catenin signaling pathway.
Yang CT, Li JM, Li LF, Ko YS, Chen JT., Free PMC Article | 03/28/2020 |
| Hyperphosphorylated paratarg-7 carrier state is a strong molecularly defined risk factor for the development of Waldenstrom's macroglobulinaemia. | Incidence and inheritance of hyperphosphorylated paratarg-7 in patients with Waldenstrom's macroglobulinaemia in Sweden.
Brandefors L, Lindh J, Preuss KD, Fadle N, Pfreundschuh M, Kimby E. | 10/26/2019 |
| The downregulation of SLP-2 by siRNA inhibited cell proliferation, elevated caspase3 activity, and decreased CCBE1 expression | The regulatory role of SLP-2 and mechanism on CCBE1 gene expression in rectal carcinoma and adjacent lymphatic tube tissues.
Guo RL, Wang XR, Wang QG, Li Z, Lu X, Miao RZ, Chang H. | 10/5/2019 |
| These findings demonstrated a positive feedback loop of SLP2 which leads to acceleration of tumor progression and poor survival of gastric cancer patients. This finding also provided evidence for the reason of SLP2 elevation. | A Positive Feedback Loop of SLP2 Activates MAPK Signaling Pathway to Promote Gastric Cancer Progression.
Ma W, Xu Z, Wang Y, Li W, Wei Z, Chen T, Mou T, Cheng M, Luo J, Luo T, Chen Y, Yu J, Zhou W, Li G., Free PMC Article | 09/7/2019 |
| that SLP-2 may predict a poor prognosis in colorectal cancer patients as a novel marker | Enhanced SLP-2 promotes invasion and metastasis by regulating Wnt/β-catenin signal pathway in colorectal cancer and predicts poor prognosis.
Zhou C, Li Y, Wang G, Niu W, Zhang J, Wang G, Zhao Q, Fan L. | 02/9/2019 |
| The knockdown of STOML2 significantly repressed the viability, migration, and invasion of LM3 cells. Authors observed that silencing STOML2 markedly downregulated the expression levels of MMP-2, MMP-9,MTA1, and nuclear factor kappa B (NF-kappaB), and upregulated levels of E-cadherin, tissue inhibitor of metalloproteinases 2 (TIMP2), and the inhibitor of kappa B (IkappaB). | Silence of Stomatin-Like Protein 2 Represses Migration and Invasion Ability of Human Liver Cancer Cells via Inhibiting the Nuclear Factor Kappa B (NF-κB) Pathway.
Zhu W, Li W, Geng Q, Wang X, Sun W, Jiang H, Pu X., Free PMC Article | 01/12/2019 |
| TROP-2, SLP-2 and CD56 were effective diagnostic markers for PTC, especially when they were combined to use. | The diagnostic value of TROP-2, SLP-2 and CD56 expression in papillary thyroid carcinoma.
Yang X, Hu Y, Shi H, Zhang C, Wang Z, Liu X, Chen H, Zhang L, Cui D. | 10/27/2018 |
| Data show that SLP-2 is upregulated by high cisplatin concentrations, leading to increased protein turnover. Overexpression of SLP-2 activates the MEK/ERK signaling pathway, and suppresses the mitochondrial apoptosis pathway, indicating that SLP-2 inhibits apoptosis by activating the MEK/ERK pathway and inhibiting the mitochondrial apoptosis pathway in cervical cancer cells. | Stomatin-like protein 2 inhibits cisplatin-induced apoptosis through MEK/ERK signaling and the mitochondrial apoptosis pathway in cervical cancer cells.
Hu G, Zhang J, Xu F, Deng H, Zhang W, Kang S, Liang W., Free PMC Article | 06/23/2018 |
| The expression of STOML2, a gene that plays a key role in mitochondrial function and T-cell activation, is associated with both IL-6 signaling and asthma risk. | Identification of STOML2 as a putative novel asthma risk gene associated with IL6R.
Revez JA, Matheson MC, Hui J, Baltic S, Australian Asthma Genetics Consortium (AAGC) collaborators, James A, Upham JW, Dharmage S, Thompson PJ, Martin NG, Hopper JL, Ferreira MA., Free PMC Article | 11/25/2017 |
| results reveal an important role of SLP2 membrane scaffolds for the spatial organization of inner membrane proteases regulating mitochondrial dynamics, quality control, and cell survival. | The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L.
Wai T, Saita S, Nolte H, Müller S, König T, Richter-Dennerlein R, Sprenger HG, Madrenas J, Mühlmeister M, Brandt U, Krüger M, Langer T., Free PMC Article | 09/9/2017 |
| Slp2 is involved in endometrial stromal cell proliferation and differentiation during decidualization in mice and humans | Stomatin-like protein 2 is involved in endometrial stromal cell proliferation and differentiation during decidualization in mice and humans.
Feng Q, Hu ZY, Liu XQ, Zhang X, Lan X, Geng YQ, Chen XM, He JL, Wang YX, Ding YB. | 08/12/2017 |
| The significant association of SLP-2 overexpression with unfavorable clinicopathological characteristics and BRAFV600E mutation indicates that SLP-2 may have a role in aggressiveness of BRAF-mutated papillary thyroid carcinoma. | Stomatin-like protein 2 overexpression in papillary thyroid carcinoma is significantly associated with high-risk clinicopathological parameters and BRAFV600E mutation.
Bartolome A, Boskovic S, Paunovic I, Bozic V, Cvejic D. | 07/30/2016 |
| Stomatin-like protein 2 is overexpressed in epithelial ovarian cancer and predicts poor patient survival | Stomatin-like protein 2 is overexpressed in epithelial ovarian cancer and predicts poor patient survival.
Sun F, Ding W, He JH, Wang XJ, Ma ZB, Li YF., Free PMC Article | 07/2/2016 |
| STOML2 was correlated to progression in cervical cancer, and implicated it as a potential predictive factor for the prognosis of cervical cancer. | Stomatin-like protein 2 expression is associated with clinical survival in patients with cervical cancer.
Xiao B, Xie Z, Guo L, Wu J, Zhang H., Free PMC Article | 02/13/2016 |
| SLP-2 was upregulated by TGF-beta1, indicating a possible role of SLP-2 in Papillary thyroid cancer tumorigenesis. | Stomatin-like protein 2 is associated with the clinicopathological features of human papillary thyroid cancer and is regulated by TGF-β in thyroid cancer cells.
Liu Z, Yang Y, Zhang Y, Ye X, Wang L, Xu G. | 09/6/2014 |